"Chorionic gonadotropin": cov lus qhia rau kev siv, analogues thiab tshuaj xyuas

Cov txheej txheem:

"Chorionic gonadotropin": cov lus qhia rau kev siv, analogues thiab tshuaj xyuas
"Chorionic gonadotropin": cov lus qhia rau kev siv, analogues thiab tshuaj xyuas

Video: "Chorionic gonadotropin": cov lus qhia rau kev siv, analogues thiab tshuaj xyuas

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Video: Tshuaj kho ncauj plab thiab ua kom txhob muaj muaj hnoos qeev thiab zoo ntau ntau yam 26 Aug 2017 2024, Kaum ib hlis
Anonim

Lo lus "tib neeg chorionic gonadotropin" yog hais txog cov tshuaj hormonal uas tuaj yeem pom hauv poj niam placenta. Nyob rau hauv cov ntshav ntawm cov txiv neej, nws kuj yog tam sim no, tab sis nyob rau hauv meager concentrations. Tam sim no, cov tshuaj nyob rau hauv lub npe lag luam Chorionic Gonadotropin tau tsim nyob rau hauv khw muag tshuaj. Nws yog ib qho lyophilisate rau kev daws rau kev txhaj tshuaj. Raws li txoj cai, cov tshuaj tau sau tseg raws li kev kho mob ntxiv rau cov poj niam thiab txiv neej.

Daim ntawv tso tawm
Daim ntawv tso tawm

Kev qhia

Chorionic gonadotropin yog ib yam tshuaj uas tsim los tswj lub cev luteum thaum cev xeeb tub. Vim li no, cov poj niam endocrine qog no tau txais lub sijhawm los tsim cov tshuaj progesterone thaum thawj 3 lub hlis ntawm kev yug menyuam. Qhov no hormone, nyob rau hauv nwstig, pab tsim ib daim nyias nyias ntawm cov hlab ntsha nyob rau hauv lub tsev me nyuam, vim hais tias lub fetus loj hlob yog ntse khaws cia nyob rau hauv nws. Tsis tas li ntawd, tib neeg chorionic gonadotropin repels niam cov hlwb tsim los ntawm kev tiv thaiv kab mob, yog li tiv thaiv tus menyuam hauv plab.

Qhov feem ntau ntawm cov tshuaj hormones yog poj niam tso zis. Qee cov tuam txhab khaws cov zis ntawm cov poj niam cev xeeb tub rau kev rho tawm tom qab ntawm tib neeg chorionic gonadotropin. Nyob rau hauv lub neej yav tom ntej, cov tshuaj no yog siv nyob rau hauv lub creation ntawm cov tshuaj tiv thaiv infertility.

Ntxiv rau, hauv cov poj niam, cov lus qhia rau kev siv tshuaj yog cov kab mob hauv qab no:

  • Hypofunction ntawm gonads cuam tshuam nrog cuam tshuam ntawm pituitary caj pas thiab hypothalamus.
  • Dysmenorrhea. Lo lus no hais txog qhov mob hauv plab, uas yog tshwm sim los ntawm spasms nyob rau hauv lub tsev menyuam thaum coj khaub ncaws los ntshav.
  • Ovarian dysfunction. Qhov no yog ib tug pathology cim los ntawm kev ua txhaum ntawm kev ua hauj lwm ntawm lub cev ua ke. Hauv particular, hormonal muaj nuj nqi yog suppressed.
  • Anovulatory infertility. Qhov no yog qhov tsis muaj peev xwm xeeb tub vim qhov tseeb tias tus poj niam lub cev tsis tso cov qe mus rau hauv txoj hlab ntshav.
  • Tsis muaj corpus luteum. Qhov no yog kab mob pathological nyob rau hauv uas progesterone yog tsim nyob rau hauv ib tug npaum li cas tsis txaus mus txuas ib lub qe fertilized mus rau lub endometrium thiab xyuas kom meej nws li qub kev loj hlob.

Raws li cov lus qhia, "Chorionic gonadotropin" raug tshuaj thiab ua tiavqhov pib ntawm cev xeeb tub, thiab thaum lactation. Nws cov lus qhia yog pom zoo tsuas yog nyob rau hauv cov ntaub ntawv ntawm insufficiency ntawm luteal theem. Nyob rau hauv lub xub ntiag ntawm tus kab mob no pathological, lub active tshuaj txhim kho zus tau tej cov progesterone, uas, nyob rau hauv lem, muaj ib tug zoo ntxim rau lub xeev ntawm lub endometrium. Yog tias cev xeeb tub thiab lactation zoo li qub, kev qhia txog cov tshuaj uas muaj hCG (chorionic gonadotropin) tsis pom zoo.

Cov tshuaj hormone kuj ua haujlwm tseem ceeb hauv cov txiv neej lub cev. Nws yog tsim los normalize testosterone synthesis los ntawm cov noob qes. Rau cov txiv neej, chorionic gonadotropin yog ib qho tseem ceeb thaum lub sij hawm puberty thiab thaum lub sij hawm hloov tshuaj hormones. Cov tshuaj kuj tswj cov spermatogenesis.

Cov tshuaj "Chorionic gonadotropin"
Cov tshuaj "Chorionic gonadotropin"

Cov lus qhia rau kev tswj hwm tshuaj rau txiv neej:

  • Hypogenitalism. Lo lus no yog hais txog kev txhim kho tsis txaus ntawm cov gonads lossis kev puas tsuaj loj hauv lawv txoj haujlwm.
  • Eunuchoidism. Qhov no yog ib tug kab mob nyob rau hauv uas muaj ib tug disproportion ntawm lub cev pob txha los yog ib tug tseem ceeb nce nyob rau hauv lub cev hnyav. Cov chav kawm ntawm tus kab mob yog nrog los ntawm inhibition ntawm lub zog ntawm gonads.
  • Testicular hypoplasia. Qhov no yog ib tug underdevelopment ntawm cov txiv neej gonads, uas ua rau txo qhov luaj li cas ntawm cov noob qes.
  • Cryptorchism. Qhov no yog kab mob congenital uas cov noob qes tsis nqis los rau hauv lub scrotum.
  • Adiposogenital Syndrome. Qhov no yog pathological mob ntawm ib tug neuroendocrine xwm, uas muaj cov cim qhia ntawm underdevelopment ntawm gonads thiabrog rog.
  • YPituitary nanism. Lwm lub npe rau tus kab mob yog dwarfism (kev ncua lub cev thiab kev loj hlob).
  • Kev deev hluas nraug. Qhov no yog ib qho teeb meem uas ib txwm muaj kev loj hlob ntawm kev ua me nyuam nres, thiab kev tsim ntawm kev sib deev yog inhibited.
  • Oligoastenospermia. Qhov no yog qhov txo qis ntawm cov kab mob nquag.
  • Azoospermia. Qhov no yog ib tug kab mob uas tsis muaj active kev sib deev hlwb nyob rau hauv ejaculation.

Yog li, Chorionic Gonadotropin yog tshuaj rau ob leeg poj niam thiab txiv neej. Cov tshuaj nquag txhawb nqa ovulation thiab spermatogenesis, muaj kev kho mob ntawm ntau yam kab mob ntawm lub cev xeeb tub, thiab tseem muaj lub luag haujlwm rau kev loj hlob ntawm cov kabmob ntawm cov menyuam yaus.

poj niam cev xeeb tub
poj niam cev xeeb tub

Composition

Cov khoom xyaw nquag ntawm cov tshuaj yog chorionic gonadotropin (1000 IU, 1500 IU, 500 IU thiab 5000 IU). Mannitol yog siv los ua ib qho excipient. Nws yog 6-hydric cawv los ntawm pawg suab thaj.

Cov kuab tshuaj yog sawv cev los ntawm sodium chloride thiab dej rau kev txhaj tshuaj. 1 ampoule muaj 1 ml ntawm kua.

Ib daim foos

Cov tshuaj yog muag raws li lyophilizate (cov hmoov qhuav) ntim rau hauv 5 ml vials. Txhua ntawm lawv muaj 500, 1000, 1500 lossis 5000 units ntawm tib neeg chorionic gonadotropin.

Cov kuab tshuaj rau cov hmoov yog nchuav rau hauv 1 ml ampoules. Tom qab ntawd cov khoom tau muab tso rau hauv cov ntim khoom thib ob - cov thawv ntawv cardboard. Txhua tus muaj 5 cov hmoov qhuav vials thiab 5 hnyav ampoules.

YContraindications

Chorionic Gonadotropin (1000 IU, 500 IU, 1500 IU lossis 5000 IU) tsis raug sau rau cov txiv neej thiab poj niam uas muaj cov kab mob hauv qab no:

  • Hypersensitivity rau ib lossis ntau yam ntawm cov tshuaj.
  • YPituitary qog (ob leeg malignant thiab benign).
  • qog nqaij hlav zes qe menyuam.
  • Neoplasms ntawm cov gonads ntawm qhov ua haujlwm hormonally.
  • Nyob rau hauv menopause.
  • Tsis muaj gonads (nws tuaj yeem yog congenital lossis kis tau).
  • YThrombophlebitis.
  • YHyperprolactinemia.
  • YAdrenal insufficiency.
  • Hypothyroidism.

"Horionic gonadotropin" (1000, 500, 1500, 5000 IU) tau sau tseg nrog kev ceev faj rau cov tub ntxhais hluas, nrog rau cov neeg muaj mob ntau zaus ntawm migraine, arterial hypertension, bronchial hawb pob, kab mob plawv thiab lub raum tsis ua haujlwm..

Nyob rau hauv chav kawm ntawm ib tus neeg sib tham nrog tus kws kho mob tuaj koom, daim ntawv teev cov contraindications tuaj yeem nthuav dav.

teem caij ntsib kws kho mob
teem caij ntsib kws kho mob

Txoj kev ntawm daim ntawv thov thiab koob tshuaj

Raws li cov lus qhia "Horionic gonadotropin" (1000, 1500, 500, 5000 IU) yog npaj rau kev txhaj tshuaj intramuscular. Kev txhaj tshuaj raug pom zoo kom ua nyob rau hauv lub tsev kho mob, tab sis nws raug tso cai nqa tawm ntawm nws tus kheej hauv tsev lossis lwm yam kev mob zoo rau tus neeg mob.

Algorithm rau intramuscularKev taw qhia ntawm "Horionic Gonadotropin" (1000, 500, 1500, 5000 IU):

  1. Thaum xub thawj, koj yuav tsum npaj txhua yam khoom siv thiab cov cuab yeej uas koj xav tau. Cov no suav nrog: cov tshuaj tov tshuaj (lyophilisate tov nrog cov kua los ntawm lub ampoule), ib lub syringe sterile syringe, kev kho mob cawv los yog cov ntaub so tshwj xeeb so rau hauv nws (lawv tuaj yeem hloov nrog paj rwb ntaub plaub). Ua ntej tuav, ntxuav koj txhais tes kom huv si nrog xab npum thiab dej.
  2. Tom qab ntawd koj yuav tsum xaiv qhov chaw txhaj tshuaj. Nws tuaj yeem yog anterior ncej puab leeg lossis gluteus maximus. Cov tom kawg yog qhov tsim kho tshaj plaws. Tsis tas li ntawd, thaum cov tshuaj txhaj rau hauv cov leeg pob txha anterior, qhov kev pheej hmoo ntawm ntau yam teeb meem yog siab dua (vim kev txhaj tshuaj tsis raug). Hauv qhov no, nws raug nquahu kom xaiv gluteal.
  3. Nws yog qhov tsim nyog los suav qhov chaw txhaj tshuaj. Txhawm rau ua qhov no, cov leeg gluteal yuav tsum pom qhov muag faib ua 4 ntu. Lub sab qaum teb cheeb tsam yog lub sab nrauv quadrant. Lub ntsiab lus xav tau yog raws nraim hauv nruab nrab ntawm nws. Kev taw qhia cov tshuaj rau hauv thaj chaw no yog qhov lees paub tias rab koob tsis kov cov hlab ntsha, cov hlab ntsha lossis cov pob txha.
  4. Qhib lub koob txhaj tshuaj, sau cov tshuaj uas yuav tsum tau ua. Tom qab ntawd nws yog ib qho tseem ceeb uas yuav tsum tau tso cov huab cua los ntawm cov cuab yeej kho mob. Muab lub syringe tso rau ntawm lub tais huv, tom qab kaw nws nrog lub hau.
  5. Muab koj tus kheej tso rau pem hauv ntej ntawm daim iav kom pom koj lub pob tw thiab qhov chaw txhaj tshuaj. Khawb cheeb tsam no. Hloov qhov hnyav mus rau lwm ceg kom qhov tsim nyog ntawm lub cev tau so kom ntau li ntau tau.
  6. Cov ntaub so ntswg los yognrog ib daim ntawm paj rwb soaked nyob rau hauv cawv, so qhov chaw txhaj tshuaj. Nqa cov koob txhaj tshuaj ntsug hauv koj txhais tes, tshem lub hau thiab coj mus rau hauv lub pob tw.
  7. Nrog lub zog nrawm, ua rau txhaj tshuaj rau hauv cov leeg kom qhov ntev ntawm qhov qhib ntawm rab koob saum daim tawv nqaij yog li 1 cm. Maj mam nias lub plunger kom txog thaum cov tshuaj sau tawm ntawm lub koob txhaj tshuaj.
  8. Ntxig lub koob thiab siv cov paj rwb los yog cawv so rau qhov chaw txhaj tshuaj. Tuav kom txog thaum cov ntshav nres tag. Qhov chaw txhaj tshuaj kuj pom zoo kom massaged. Qhov no yuav pab kom tsis txhob muaj cov ntsaws ruaj ruaj thiab txhawb nqa kev nqus zoo ntawm cov tshuaj.
  9. Kev txhaj tshuaj intramuscular
    Kev txhaj tshuaj intramuscular

Lub sijhawm ntawm chav kawm thiab qhov ntau npaum li cas ntawm Chorionic Gonadotropin (1500 IU, 500 IU, 1000 IU, 5000 IU) yog txiav txim los ntawm tus kws kho mob tuaj koom ntawm tus kheej. Tshwj tsis yog tus kws tshaj lij tau qhia lwm yam, koj yuav tsum ua raws li cov lus pom zoo:

  • Rau cov txiv neej, cov tshuaj tau muab ob zaug lossis peb zaug hauv ib lub lis piam. Lub sijhawm kho yog 28 hnub. Tom qab ntawd koj yuav tsum tau so rau 4 lub lis piam. Tom qab ntawd, chav kawm yuav tsum tau rov ua dua. Muaj 3 lossis 6 ntawm lawv tag nrho rau 6 lub hlis lossis 1 xyoos. Yog tias koj nkag mus rau "Chorionic gonadotropin" (1500, 500, 1000 lossis 5000 IU) yam tsis muaj kev cuam tshuam thiab ntev, kev pheej hmoo ntawm kev tsim cov tshuaj tiv thaiv thiab kev ua haujlwm tsis zoo ntawm cov qog pituitary yuav nce ntxiv.
  • Txoj kev ntawm daim ntawv thov rau anovulation, cov chav kawm uas yog nrog los ntawm ib txwm maturation ntawm lub hauv paus, yog raws li nram no. Kev kho mob yuav tsum tau pib txij hnub tim 10 lossis 12 hnub ntawm kev coj khaub ncaws ob zaug lossis peb zaug hauv ib hnub ntawm qhov koob tshuaj ntawm 3000 IU. Ces koj xav tauso 2 lossis 3 hnub. Nws tseem raug tso cai los tswj cov tshuaj ntawm ib koob ntawm 1500 units 6 lossis 7 zaug hauv ib hnub.
  • Siv rau pituitary dwarfism thiab kev sib deev infantilism raws li hauv qab no. Chorionic gonadotropin (5000, 1500, 1000, 500) yog muab 1 lossis 2 zaug hauv ib lub lis piam ntawm qhov ntau npaum li 1000 IU. Lub sijhawm kawm - 1-2 lub hlis. Yog tias tsim nyog, nws tuaj yeem rov ua dua.
  • Txhawm rau ua kom ovulation, cov tshuaj tau muab tshuaj ib zaug ntawm qhov tshuaj ntawm 5000-10,000 IU. Ib qho qauv zoo sib xws yuav tsum tau ua raws li thaum ua cov dej num ntxiv me nyuam.
  • Thaum muaj pituitary insufficiency, nws raug nquahu kom pib kho tsuas yog tom qab kev kho ua ntej follicle-stimulating.

Ntau zaus, cov tshuaj tau muab rau cov txiv neej rau kev kuaj mob. Hauv qhov no, tus neeg sawv cev yuav tsum tau muab tshuaj rau 5 hnub ntawm qhov ntau npaum li 1500 lossis 3000 IU.

Hauv cov menyuam yaus, kev kho mob nrog Chorionic Gonadotropin yog qhov zoo tshaj plaws kom txog thaum lawv muaj hnub nyoog 10 xyoo. Kev noj ntau npaum li cas thiab lub sijhawm ntawm kev kho mob yog txiav txim siab los ntawm tus kws kho mob hauv lub hauv paus ntawm tus kab mob uas twb muaj lawm, nws qhov hnyav, nrog rau tus kheej tus yam ntxwv ntawm tus menyuam txoj kev noj qab haus huv. Thaum tsis muaj cov lus pom zoo los ntawm tus kws kho mob tshwj xeeb, nws yog qhov yuav tsum tau ua raws li cov txheej txheem kev kho mob. Raws li cov lus qhia rau cov me nyuam, cov tshuaj yuav tsum tau muab ob zaug ib lub lim tiam rau 1-1.5 lub hlis ntawm ib koob ntawm 1000 los yog 1500 IU.

Side effects

Raws li kev tshuaj xyuas, Chorionic Gonadotropin tau txais txiaj ntsig zoo los ntawm cov neeg mob feem ntau. Txawm li cas los xij, qhov kev pheej hmoo ntawm kev tsis zoo tshwm sim tseem nyob.

Rau lawvsuav nrog:

  • Headache.
  • mob siab, hyperemia ntawm qhov chaw txhaj tshuaj.
  • Tshuaj tawv nqaij.
  • Nyob rau hauv qhov kev xav ntawm qaug zog.
  • Psycho-emotional instability.
  • Kev xav tsis meej txog kev ntxhov siab.
  • Kev nyuaj siab.
  • YPituitary dysfunction.

Tsis tas li ntawd, txiv neej kuj tseem muaj cov kev mob tshwm sim hauv qab no:

  • Nyob ntawm qhov extremities.
  • Kev tso zis.
  • High degree ntawm lub txiv mis rhiab heev.
  • Ntxhais qe menyuam loj.

Tawm tsam keeb kwm yav dhau los ntawm kev siv mus sij hawm ntev, kev hloov pauv hauv cov qog nqaij hlav tuaj yeem tshwm sim. Kuj tseem muaj kev pheej hmoo ntawm kev tsim atrophy ntawm cov tubules seminiferous thiab txo cov spermatozoa hauv ejaculate.

Kev mob tshwm sim
Kev mob tshwm sim

Ntau tshaj

Tus mob no yuav tshwm sim thaum noj cov tshuaj ntau dua li qhov siab tshaj plaws uas tau tso cai.

Cov tsos mob hauv qab no yog ceeb:

  • mob plab;
  • xav nroo ib tsam;
  • ntua;
  • ua tsis taus pa;
  • mob plab.

Nyob rau hauv cov poj niam uas muaj kev noj ntau dhau ntawm Chorionic Gonadotropin, hlwv tsim ntawm zes qe menyuam, uas tuaj yeem tawg tau txhua lub sijhawm. Tsis tas li ntawd, cov kua dej tuaj yeem pib ua rau hauv plab thiab pleural kab noj hniav.

Tus tshuaj tiv thaiv tsis paub. Kev kho mob ntau dhau suav nrog kev kho cov tsos mob.

Analogues

Tam sim no, ntau hom tshuaj tau muag hauv khw muag tshuaj, cov khoom siv uas yog tib neeg chorionic gonadotropin.

Cov tshuaj siv dav dav tshaj plaws:

  • "Ua ntej". Nws kuj yog ib qho lyophilisate rau kev npaj tshuaj. Cov npe ntawm cov lus qhia zoo ib yam rau Chorionic Gonadotropin, tab sis cov tshuaj muaj kev phiv ntau dua.
  • "Profazi". Muaj nyob rau hauv ob koob tshuaj - 2000 thiab 5000 IU. Cov cuab yeej muaj qhov qhia tib yam, thaum daim ntawv teev cov kev txwv yog dav dua.
  • "Horagon". Cov lyophilisate yog muag tag nrog cov kuab tshuaj ntawm ib koob ntawm 1500 thiab 5000 IU. Ntawm tag nrho cov analogues, nws muaj cov npe zoo tshaj plaws ntawm contraindications.
  • "Choral". Cov lus qhia rau kev siv yog tib yam rau Chorionic Gonadotropin.
  • "Ecostimulin". Muaj nyob rau hauv daim ntawv ntawm lyophilisate rau kev npaj cov tshuaj npaj rau ob leeg intramuscular thiab subcutaneous tswj.

Yog tias, vim li cas, tus neeg mob xav yuav cov tshuaj analogue, nws yuav tsum tau txais kev tso cai los ntawm tus kws kho mob. Qhov no yog vim qhov tseeb tias txhua yam tshuaj muaj qee yam contraindications, ntau npaum li cas thiab kev kho mob.

Reviews

Raws li cov neeg mob, Chorionic Gonadotropin tau txais txiaj ntsig zoo los ntawm cov neeg feem coob. Tib lub sijhawm, cov cuab yeej muaj kev ua haujlwm siab.

Cov kws kho mob feem ntau sau tshuaj chorionic Gonadotropin rau lawv cov neeg mob vim qhov tseeb tias cov tshuaj hauv lub sijhawm luv luvpab tiv nrog cov kab mob uas twb muaj lawm lossis txhim kho nws txoj kev kawm. Tsis tas li ntawd, koj tuaj yeem yuav nws ntawm yuav luag txhua lub tsev muag tshuaj.

Tshuaj kho mob
Tshuaj kho mob

Nyob hauv kaw

Chorionic gonadotropin yog ib yam tshuaj muaj nyob hauv poj niam placenta. Nyob rau tib lub sijhawm, cov tuam txhab tsim khoom feem ntau tso tawm cov tshuaj los ntawm cov zis ntawm cov poj niam cev xeeb tub.

Cov tshuaj "Chorionic gonadotropin" yog npaj rau kev kho mob ntawm cov kab mob ntawm cov menyuam yaus hauv cov poj niam thiab cov txiv neej. Cov tshuaj yog muab intramuscularly nyob rau hauv cov koob tshuaj qhia los ntawm tus kws kho mob. Thaum tsis muaj cov lus pom zoo tshwj xeeb, cov txheej txheem kho mob yuav tsum ua raws.

Pom zoo: