"Eliquis" - ib yam tshuaj uas tsim nyob rau hauv Teb Chaws Asmeskas, yog ib qho kev xaiv inhibitor ntawm cov ntshav txhaws. Vim yog tus nqi siab, tib neeg feem ntau raug yuam kom nrhiav ib qho analogue. Eliquis muaj ob peb.
"Eliquis" - cov lus qhia rau kev siv
Cov khoom xyaw nquag hauv cov tshuaj muaj pes tsawg leeg yog apixaban. Muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm 2, 5 thiab 5 mg, 20 los yog 60 daim ib pob. Lub mechanism ntawm nws qhov kev txiav txim ntawm lub cev yog kom qeeb cov kev ua ntawm cov ntshav coagulation yam. Qhia rau siv rau kev tiv thaiv ntawm venous thromboembolism tom qab prosthetic lub hauv caug los yog lub duav pob qij txha. Cov tshuaj yog siv nyob rau hauv kev saib xyuas nruj ntawm ib tus kws kho mob tshwj xeeb, vim tias muaj kev pheej hmoo los ntshav. Qhov no yog qhov tseeb tshwj xeeb tshaj yog rau cov neeg mob los ntshav, kab mob peptic ulcers ntawm plab hnyuv, arterial hypertension, kab mob endocarditis, hemorrhagic stroke.
Tseem muaj kev pheej hmoo yog cov neeg uas tau txais kev phais ntawm lub hlwb lossis tus txha caj qaum, phais kho qhov muag. Contraindications: kev tsis haum tshuaj, kab mob ntawm daim siab, ob lub raum, cev xeeb tub,lactation, hnub nyoog qis dua 18 xyoo, cov kab mob cuam tshuam nrog cov ntshav txhaws tsis zoo thiab muaj feem yuav los ntshav. Cov neeg mob nco ntsoov nws cov kev ua haujlwm siab hauv lub sijhawm postoperative. Tab sis tus nqi siab (kwv yees li 2,500 rubles rau ib pob loj ntawm 60 ntsiav tshuaj) yuam koj xaiv cov analogues pheej yig dua li Eliquis.
Xarelto. Description
"Xarelto" ua nyob rau hauv lub teb chaws Yelemees - qhov nrov tshaj plaws analogue ("Eliquis" muaj ib tug txawv active ingredient). Cov tshuaj yog ib tug ncaj-acting anticoagulant. Muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm 5 thiab 10 pieces. Cov khoom xyaw nquag - rivaroxaban, uas yog ib qho ncaj qha inhibitor ntawm ntshav coagulation yam Xa, muaj bioavailability siab thaum noj sab hauv. Thaum kho, tsis tas yuav saib xyuas cov ntshav txhaws tas li.
Cov tshuaj yog nqus tau sai, qhov siab tshaj plaws tau pom 2-4 teev tom qab noj, tsis hais txog kev noj zaub mov. Excreted nrog zis thiab quav. Siv los tiv thaiv venous thromboembolism tom qab phais qis dua.
Contraindications thiab phiv
Ntau yam ntawm contraindications muaj ib qho analogue ("Eliquis" kuj nplua nuj nyob rau hauv lawv). Cov no suav nrog:
• hypersensitivity rau cov tshuaj tivthaiv, lactose intolerance;
• active los ntshav (intracranial, gastrointestinal);
• Cov kab mob cuam tshuam nrog kev pheej hmoo los ntshav (pas plab rwj, qog nqaij hlav cancer, mob hlwb lossis txha caj qaum, mob hlwb, thiab lwm yam);
• ib txhijsiv lwm cov tshuaj anticoagulants;
• kab mob siab nrog rau kev pheej hmoo los ntshav (cirrhosis B thiab C chav kawm);
• cev xeeb tub, lactation;
• Hnub nyoog qis dua 18 xyoo.
Tsis pom zoo rau lub raum tsis ua haujlwm hnyav. Ib yam li cov tshuaj Eliquis, cov tshuaj analogue muaj cov npe ntev ntawm qhov tshwm sim tsis zoo.
Cov kev mob tshwm sim tshwm sim hauv daim ntawv ntawm kev ua haujlwm tsis zoo:
- hematopoietic systems (anemia, thrombocythemia);
- kab mob plawv (hypotension, tachycardia);
- lub cev tsis pom kev (ocular hemorrhage);
- digestive system (pab plab los ntshav, pos hniav, qhov quav; mob, xeev siab, cem quav, raws plab, ntuav);
- liab (jaundice);
- paj hlwb (kiv taub hau, mob taub hau, tsis tshua muaj fainting);
- genitourinary system (los ntshav);
- ua pa (nosebleed);
- tiv thaiv kab mob (xws li tshuaj tiv thaiv kab mob);
- daim tawv nqaij (khaus, pob khaus).
Thaum kho nrog tshuaj, mob hauv caj dab, ua npaws, ua rau lub cev tsis zoo.
YWarfarin
"Warfarin" yog lwm qhov analogue ("Eliquis", tsis zoo li nws, yog cov tshuaj tiv thaiv kab mob ncaj qha). Nrov tsim nyob rau hauv Denmark "Warfarin Nycomed". Tsis tas li ntawd hauv khw muag tshuaj koj tuaj yeem nrhiav Latvian Varfarex, Finnish Marevan, Lavxias Warfarin. Piv nrog rau lwm yam hloov pauv rau Eliquis, cov analogues hauv tsev yog qhov pheej yig tshaj plaws.
Cov khoom xyaw nquag muaj warfamin yog ib qho tshuaj tiv thaiv tsis ncaj, ib qho derivative ntawm coumarin. Nws tawm sai sai los ntawm lub cev los ntawm txoj hnyuv thiab daim tawv nqaij. Qhia rau siv nyob rau hauv kev kho mob thiab tiv thaiv cov hlab ntsha embolism, postoperative thrombosis, recurrent myocardial infarction, thiab prosthetic lub plawv li qub. Siv rau hauv kev kho mob thrombosis (phais lossis kho mob) raws li kev kho mob ntxiv.
YWarfamin contraindications
Vim muaj ntau cov kev mob tshwm sim, cov lus qhia rau kev siv yuav tsum tau ua tib zoo kawm ua ntej noj Eliquis. Analogues tsis poob qab hauv qhov no thiab muaj cov nram qab no contraindications:
- ntshav pathology, nws hloov pauv;
- kab mob uas txaus ntshai los ntshav;
- paj hlwb tsis ntev los no, qhov muag phais;
- GI plab;
- kab mob ntawm txoj hlab pa;
- aneurysms;
- DIC;
- mob siab thiab mob raum;
- kab mob ntawm cov kab mob genitourinary;
- hlab ntshav siab;
- pregnancy.
Txawm tias nws muaj kev nyab xeeb rau kev siv los ntawm cov neeg muaj hnub nyoog qis dua 18 xyoo tsis tau tsim.
Cov kev phiv tshwm sim:
- ntshav, ntshav liab, tawv nqaij necrosis;
- Dermatitis, pob tawm tawv nqaij, khaus, o;
- xeev siab, mob plab, ntuav, kab mob siab, raws plab;
- -ua daus no, vasculitis;
- mob taub hau, kiv taub hau, nkees nkees, saj cuam tshuam.
Pradaxa
"Pradaksa" - ua nyob rau hauv lub teb chaws Yelemees analogue ("Eliquis" txawv nyob rau hauv muaj pes tsawg leeg). Nws yog ib qho ncaj qha inhibitor ntawm thrombin. Cov khoom xyaw nquag yog dabigatran etexilate mesilate. Muaj nyob rau hauv daim ntawv ntawm cov tshuaj ntsiav ntawm 10 thiab 60 daim ib pob. Thaum noj, nws yog sai absorbed nyob rau hauv lub plab. Pradaxa yog siv los tiv thaiv:
- venous thromboembolism tom qab kev phais qis qis;
- mob stroke thiab kab mob thromboembolism;
- recurrent thrombosis;
- YPulmonary embolism.
Nws kuj yog ib qho kev kho mob rau mob thrombosis. Pradaxa txo tus neeg tuag vim yog cov kab mob no.
Contraindications rau kev siv "Pradaksa"
Muaj ntau yam kev mob tshwm sim tau hais txog cov tshuaj "Eliquis" tshuaj xyuas. Analogues kuj muaj lawv tus kheej contraindications thiab tej zaum yuav tsis zoo txim. Contraindications suav nrog:
- hypersensitivity rau active lossis auxiliary Cheebtsam ntawm cov tshuaj;
- lub raum tsis ua haujlwm (hnyav);
- ua haujlwm los ntshav, impaired hemostasis, hemorrhagic diathesis;
- lub cev puas tsuaj vim los ntshav;
- GI rwj;
- malignant qog;
- mob hlwb, raug mob qaum qaum, kev phais tsis ntev los no;
- yav dhau los intracranial hemorrhage;
- kab mob siab, ua haujlwm tsis zoo;
- vascular aneuryms;
- noj lwm cov tshuaj tiv thaiv kab mob.
Cov ntaub ntawv ntawm cov tshuaj muaj txiaj ntsig rau cov neeg mob hnub nyoog qis dua 18 xyoo tsis muaj. Nrog kev ceev faj, cov tshuaj siv nrog txo qis hauv lub raum ua haujlwm, tus neeg mob hnyav dua 50 kg, cov neeg muaj hnub nyoog tshaj 75 xyoo thiab muaj cov kab mob uas muaj feem yuav los ntshav.
Cov teebmeem uas yuav tshwm sim thaum noj zoo ib yam li cov tshuaj yav dhau los:
- xiav;
- daim tawv nqaij mob;
- mob plawv, digestive, ua pa, genitourinary systems;
- Kuv ua daus no, kub taub hau, mob taub hau, mob ib ce thiab lwm yam.
Sib piv tus nqi
Raws li nws tau pom meej lawm, hauv cov khw muag tshuaj koj tuaj yeem yuav cov tshuaj hloov pauv rau Eliquis. Analogues yog pheej yig dua, tab sis tsis muaj tsawg-zoo, lawv yog tsim nyob rau hauv ntau lub teb chaws, nrog ib tug sib txawv muaj pes tsawg leeg ntawm ib leeg. Yog li ntawd, lawv cov nqi sib txawv. Yog li, tus nqi nruab nrab ntawm "Xarelto" yog nyob rau hauv 1500 rubles. Yuav "Pradaksa" yuav raug nqi 700-800 rubles. Qhov kev xaiv peev nyiaj tshaj plaws yog kev npaj raws li warfamin. Lawv tau tsim los ntawm cov tuam txhab tshuaj hauv ntau lub tebchaws. "Warfarin Nycomed" Danish ntau lawm - txog 150 rubles. Tus nqi ntawm Finnish "Marevan" yog nyob rau tib yam. Tsis zoo li cov tshuaj kim kim Eliquis, analogues yog pheej yig dua, tab sis tsis qis dua qhov zoo. Qhov no tau lees paub los ntawm ntau qhov xwm txheej ntawm kev ua tiav ntawm lub sijhawm postoperative. Cov analogues pheej yig tshaj plaws ntawm kev tsim khoom hauv tsev, xws li "Warfarin", nws yuav raug nqi txog 70 rubles.