Qhov kev kuaj pom tsis meej ntawm "folate deficiency anemia" tuaj yeem hnov ntau zaus. Nws txhais li cas? Ua ntej tshaj plaws, kev lees paub ntawm tus mob no qhia tau tias tsis txaus ntawm cov vitamin B12 lossis B9 (folate) hauv cov ntshav.
Folate (folic acid ntsev) yog xav tau los ntawm lub cev los tsim cov qe ntshav liab tshiab, lub luag haujlwm xa cov pa oxygen mus rau hauv nruab nrog cev. Nrog rau lawv cov lej qis, cov ntshav tsis txaus, ua rau tus neeg mob qaug zog thiab nkees.
Yog tias koj tau kuaj pom tias muaj vitamin B12-folate deficiency anemia thaum cev xeeb tub, muaj kev pheej hmoo ntawm fetal malformations xws li spina bifida. Qhov teeb meem no ua rau tus me nyuam tus txha nraub qaum deformation.
Nrog rau qhov kev kuaj pom tseeb, koj tuaj yeem siv cov tshuaj tshwj xeeb thiab cov khoom noj khoom haus lom neeg lom zem nrog cov ntsiab lus siab ntawm folic acid - qhov no yuav txo qhov kev pheej hmoo ntawm kev tsis zoo ntawm tus me nyuam hauv plab, thiab yog tias tsis muaj cov ntsiab lus hais txog. tsis cuam tshuam nrog ntshav qab zib, nws yuav tiv thaiv kev txhim kho ntawm qhov xwm txheej txaus ntshai.
BritishCov kws tshawb fawb tau xaus lus tias kev tswj hwm qib folate hauv cov ntshav ib txwm pab txo qis kev pheej hmoo ntawm cov kab mob plawv thiab mob qog noj ntshav.
folic acid yog dab tsi
Folic acid yog ib qho hluavtaws analogue ntawm vitamin B9, tseem hu ua folate. Cov vitamin no yog ntxuav tawm ntawm lub cev nrog hws thiab tso zis. Nws tsis khaws cia rau hauv lub cev, yog li txhua txhua hnub koj yuav tsum tau noj zaub mov uas muaj vitamin B9 txaus. Tib yam muaj tseeb rau vitamin B12, uas feem ntau qis tib lub sijhawm nrog cov folate hauv kev kuaj mob ntawm vitamin B-12-folate deficiency anemia.
Yog vim li cas
Qhov laj thawj tseem ceeb rau kev loj hlob ntawm cov kab mob pathological yog monotonous malnutrition. Feem ntau, kev noj zaub mov tsis muaj cov vitamins lossis kev kho cua sov ntau ntawm cov zaub mov (kib, stewing, steaming, boiling, grilling, siv lub qhov cub microwave) ua rau muaj kev pheej hmoo. Folic acid muaj nyob rau hauv me me nyob rau hauv feem ntau cov zaub mov, tab sis citrus txiv hmab txiv ntoo, ntsuab nplooj zaub, thiab fortified cereals thiab muesli tshwj xeeb tshaj yog nplua nuj nyob rau hauv nws. Muaj tsawg zaus, qhov tshwm sim tsis zoo - qhov tsis muaj peev xwm nqus tau cov folic acid txaus los ntawm cov zaub mov nkag mus rau hauv lub cev. Kev ntshav ntau dhau tuaj yeem ua rau mob ntshav qab zib.
Tsis tas li, vitamin B-12-folate deficiency anemia tuaj yeem tshwm sim los ntawm:
- Kev xeeb tub. Thaum lub sij hawm no, tus nqi ntawm assimilation ntawm folates txo. Tsis tas li ntawd,lub fetus loj hlob pib noj cov vitamin B9 los ntawm leej niam lub cev. Toxicosis cuam tshuam nrog ntuav kuj ua rau poob ntawm cov khoom tseem ceeb.
- Malabsorption (tsis txaus nqus). Qhov teeb meem no raug kuaj pom thaum muaj qhov nqus tsis txaus thiab assimilation ntawm qee cov vitamin lossis ntxhia. Folic acid nqus tau cuam tshuam los ntawm qee yam kab mob thiab cov tshuaj noj. Piv txwv li, kab mob celiac (gluten intolerance) los yog cov tshuaj tsim los tiv thaiv qaug dab peg tuaj yeem ua rau malabsorption.
Yog li, raws li koj tau nkag siab, tawm tsam keeb kwm ntawm tag nrho cov saum toj no, folic deficiency anemia tshwm sim. Lub pathogenesis suav nrog kev ua txhaum ntawm DNA synthesis vim qhov txo qis ntawm cov tshuaj folic acid hauv cov ntshav.
Risk factors
Summarized, cov kev pheej hmoo ua rau kev loj hlob ntawm ib qho mob xws li vitamin-B12-folate deficiency anemia tuaj yeem raug sau tseg raws li hauv qab no:
- kev ua phem rau kev kho cua sov ntawm zaub mov;
- vitamin deficiency noj;
- nquag haus cawv (cawv cuam tshuam nrog kev nqus folate);
- qee yam kab mob (xws li mob qog ntshav ntshav ntshav);
- tshuaj (cov pab pawg no feem ntau suav nrog tshuaj kho mob qog noj ntshav, mob caj dab thiab qaug dab peg);
- pregnancy.
Cov tsos mob thiab cov tsos mob
Tam sim no, ntau thiab ntau tus neeg ntawm cov hnub nyoog sib txawv tau kuaj pomfolate deficiency anemia. Cov tsos mob ntawm tus mob no tau teev tseg hauv qab no. Nov yog:
- xav nkees;
- pom cov kab mob hauv qhov ncauj;
- plaub hau grey;
- tus nplaig o;
- kev loj hlob qeeb hauv menyuam yaus.
Txawm hais tias cov tsos mob no sib txawv nrog folate deficiency anemia, cov tsos mob ntawm qhov zoo sib xws tshwm sim hauv cov neeg mob uas tsis muaj folate, tsis cuam tshuam nrog ntshav ntshav, thiab hauv cov neeg uas noj zaub mov tsis txaus lossis tsis txaus.
Cov hauv qab no feem ntau ntxiv rau cov yam ntxwv tseem ceeb:
- kiv taub hau;
- chim siab;
- mob taub hau;
- ua tsis taus pa;
- daim tawv nqaij;
- mob plab;
- poob ceeb thawj;
- poob qab los;
- kev nyuaj siab.
Diagnosis
Vim cov tsos mob saum toj no yuav qhia tau tias muaj lwm yam kab mob ntshav, koj yuav tsum sab laj nrog tus kws kho mob kom paub qhov tseeb. Vitamin-B12-folate deficiency anemia yog txiav txim siab los ntawm cov txiaj ntsig ntawm cov ntshav suav. Txoj kev tshawb no pab tshawb nrhiav cov qe ntshav liab tsis txaus.
Tej zaum tus kws kho mob yuav sau cov kev tshawb fawb tshwj xeeb los txiav txim siab qib ntawm folic acid. Yog tias tus neeg mob yog ib tug poj niam uas muaj hnub nyoog yug me nyuam, nws yuav xav tau kev kuaj cev xeeb tub ntxiv, vim lub cev yuav coj cov folic acid ntau rau kev loj hlob ntawm tus menyuam hauv plab. Tsis tas li ntawd,Koj yuav tsum tau teb cov lus nug txog kev noj zaub mov kom txiav txim siab qhov ua tau ntawm pathology vim tsis muaj zaub mov noj.
Yog tias koj noj tshuaj, nco ntsoov qhia rau koj tus kws kho mob paub tias qee cov tshuaj tuaj yeem ua rau lossis ua rau folate thiab vitamin B12 tsis txaus.
Kev kho mob
Thaum kuaj pom ntawm folate deficiency anemia tau lees paub, kev kho mob yuav tsom mus rau kev nce qib folic acid. Txoj hauv kev yooj yim tshaj plaws los ua kom cov qib folate ntxiv yog noj cov tshuaj vitamin hauv cov ntsiav tshuaj kom txog thaum cov ntshav tsis ploj. Txawm li cas los xij, nrog rau qhov tshwj xeeb qis ntawm cov vitamin B9 hauv cov ntshav, cov tshuaj folic acid rau hauv cov hlab ntsha.
Tib lub sijhawm noj tshuaj thiab cov khoom noj khoom haus lom neeg lom zem, koj yuav tsum nce kev noj zaub mov nplua nuj ntawm cov khoom hais. Cov no suav nrog spinach thiab lwm cov nplooj ntsuab ntsuab, pinto taum, thiab txiv kab ntxwv. Noj zaub mov tshiab ntxiv thiab zam cov zaub mov kib uas muaj roj ntau thiab tsis muaj cov as-ham tiag tiag li ntau li ntau tau.
Txhawm rau tiv thaiv qhov tshwm sim ntawm qhov teeb meem xws li vitamin-B12-folate deficiency anemia, cov kws tshawb fawb Askiv pom zoo kom noj 400 mg ntawm folic acid txhua hnub. Thaum cev xeeb tub, qee yam kab mob thiab cov kab mob pathological ntawm lub cev, qhov xav tau ntawm cov tshuaj no tuaj yeem nce ntxiv. Qhov siab tshaj plaws koob tshuaj uas tsis muaj kev phom sij ntau tshaj qhov ntsuas yog 1000 mg ntawm folic acid. Qhov tseeb txaus siab: daim ntawv hluavtaws ntawm vitamin B9 yog absorbed zoo dua li ntujfolate pom nyob rau hauv cov khoom noj. Qhov no yog vim li cas txawm tias cov neeg uas noj cov zaub mov uas muaj cov khoom noj muaj txiaj ntsig ntau li ntau tau feem ntau yuav tsum tau noj cov tshuaj folate ntxiv.
Tshawb xyuas nrog koj tus kws kho mob ua ntej siv folic acid thiab tshuaj noj tshwj xeeb.
Huab cua
Kev kho mob txaus ntawm B12-folate deficiency anemia ua rau muaj kev txhim kho ntawm qhov zoo thiab qhov kawg nyem ntawm cov tsos mob ntawm tus mob no. Cov neeg mob zoo, raws li txoj cai, tsis raug kev txom nyem los ntawm kev rov qab los. Kev kho mob hnyav feem ntau kav ntev li ob lub hlis.
Muaj Teeb Meem
Cov tsos mob ntawm lub xeev txheeb xyuas qhov sib txawv ua rau tsis xis nyob. Txij li thaum folate deficiency anemia feem ntau tshwm sim thaum cev xeeb tub, kev kuaj mob yuav tsum tau raws sijhawm thiab ua kom tiav raws li qhov ua tau txhawm rau txhawm rau tshem tawm cov kab mob hauv lub cev tsis zoo ntawm tus me nyuam hauv plab (koom nrog kev ua tsis zoo ntawm tus txha caj qaum thiab cov hlab ntsha neural).
Ntxiv rau, cov teeb meem hauv qab no tau raug sau tseg hauv kev tshawb fawb thiab kev kho mob:
- pom cov plaub hau grey ntxov ntxov (cov plaub hau ncaj feem ntau pib curl);
- nce daim tawv nqaij pigmentation;
- kev muaj menyuam;
- deterioration hauv kab mob plawv lossis lub plawv tsis ua haujlwm.
Kev Tiv Thaiv
Folic deficiency anemia yog ib yam mob uas yooj yim los tiv thaiv. txaus nojntau cov khoom noj uas muaj folic acid. Kev pom zoo noj txhua hnub ntawm 400 mg (ntxiv rau kev noj haus) yog tsim rau txhua tus poj niam. Koj yuav tsum tau ua raws li lub tswv yim ua ntej lub tswv yim npaj thiab thaum thawj peb lub hlis twg ntawm cev xeeb tub.
Zoo kawg
Txawm hais tias cov kev xav ntawm cov kws tshawb fawb txog kev xav tau kev tiv thaiv tshuaj tiv thaiv kab mob xws li folate deficiency anemia tseem txawv (tsis yog txhua tus kws kho mob paub tseeb tias cov txiaj ntsig ntawm kev noj tshuaj ntxiv ntawm folic acid), muaj pov thawj tseeb tias qee qhov kev mob tshwm sim nyob ntawm seb. vim tsis muaj folate thiab vitamin B12. Kev sib xyaw cov khoom noj nrog cov ntsiab lus siab ntawm cov khoom hais hauv cov khoom noj tsis tu ncua muaj nws qhov zoo:
- txo qhov kev pheej hmoo ntawm atherosclerosis;
- tiv thaiv qhov tshwm sim ntawm kev raug mob hauv hlwb;
- pab tiv thaiv cov hlab ntsha neural tsis xws luag hauv fetus thaum noj folic acid ua ntej thiab thaum cev xeeb tub;
- Pab txo qis kev pheej hmoo ntawm kev puas hlwb thiab kev puas siab puas ntsws cuam tshuam nrog ntshav qab zib gestational hauv cov menyuam yug tshiab.
Ntxiv cov folic acid yav dhau los xav kom txo qis kev pheej hmoo ntawm mob qog noj ntshav. Txawm li cas los xij, tam sim no muaj pov thawj ntawm qhov cuam tshuam tsis zoo: qee zaum, cov ntsiab lus ntxiv ntawm cov tshuaj no hauv lub cev ua rau kev loj hlob ntawm cov kab mob pathologically hloov pauv thiab ua rau muaj kev loj hlob ntawm cov kab mob oncological. Yog li, ua ntej siv folate, nws yuav tsum tau sab laj nrog kws kho mob thiab xyuas kom tseeb tias koj tsis muaj contraindications rau kev noj cov tshuaj folate.vitamin B9.
