Cov tshuaj "Sydnopharm" yog ib qho khoom siv peripheral uas tuaj yeem nthuav cov lumen ntawm cov hlab ntsha thiab txo qis hauv lawv. Tsis tas li ntawd, cov tshuaj pab tiv thaiv thiab txo qhov mob angina, yog siv los kho lwm cov tsos mob ntawm coronary insufficiency.
Yuav ua li cas cov tshuaj ua haujlwm
txhais tau tias "Sydnopharm" yog tus pub ntawm nitric oxide, tso tawm nrog kev pab los ntawm cov tshuaj nyob rau hauv cov txheej txheem ntawm metabolic tshua. Qhov no binary compound stimulates ntau lawm
soluble guanylate cyclase, qhov nce ntxiv uas ua rau kom so ntawm cov leeg nqaij hauv cov hlab ntsha. Yog li ntawd, lub nra ntawm lawv cov phab ntsa raug txo, thiab vim li ntawd, qhov sib npaug ntawm qhov xav tau oxygen thiab nws nkag mus rau hauv cov ntshav tau rov qab los. Cov hlab ntsha nqaim, uas muaj peev xwm ncab, nthuav dav hauv qab ntawm cov tshuaj "Sydnopharm".
Tsis tas li, cov tshuaj maj mam tso tawm thiab kev sib txuas ntawm thromboxane thiab serotonin, uasua rau kev tawm tsam ntawm cov theem pib ntawm kev sib sau ntawm cov enzymes thiab tiv thaiv cov ntshav txhaws.
Pharmacological action
Cov tshuaj "Sydnopharm" ua li cas rau tib neeg lub cev? Cov lus qhia rau kev siv hais tias raws li qhov tshwm sim ntawm kev siv tus neeg sawv cev no nyob rau hauv lub lateral (bypass) txoj kev ntawm cov ntshav khiav, cov ntshav khiav zoo. Tsis tas li ntawd, cov tshuaj no ua rau kom muaj kev ua siab ntev thiab txo qhov zaus ntawm angina tawm tsam uas tshwm sim nrog kev siv zog ntawm lub cev.
Ntawm lwm yam, cov tshuaj "Sydnopharm" nqaim cov chav hauv plawv thaum lub plawv tsis ua haujlwm, txo qis hauv cov hlab ntsha ntawm lub ntsws. Raws li qhov tshwm sim ntawm qhov tshwm sim no, sab laug ventricle ntawm tib neeg lub cev tseem ceeb yog cov ntshav tsis txaus, thiab cov leeg nqaij myocardial txo qis.
Lub sijhawm ntawm kev ua yeeb tshuaj
Tus neeg mob tus mob sai npaum li cas thaum nws noj Sydnopharm? Kev tshuaj xyuas ntawm ntau tus neeg mob thiab cov lus qhia rau kev siv qhia tau hais tias nws zoo thiab sai sai absorbed los ntawm digestive system. Cov nyhuv ntawm cov tshuaj "Sydnopharm" tuaj yeem pom 20 feeb tom qab nws noj lossis tom qab 5-10 feeb yog tias koj tso cov tshuaj hauv qab tus nplaig. Cov tshuaj tiv thaiv siab tshaj plaws ntawm lub cev rau cov tshuaj yog pom ntawm 30 thiab 60 feeb tom qab noj nws. Siv tau rau 6 teev.
Tshuaj "Sydnopharm" xyaum tsis khi rau plasma proteins. Cov txheej txheem ntawm cov tshuaj metabolism tshwm sim nyob rau hauv daim siab, thiab nws yog excretedfeem ntau yog los ntawm lub raum. Nyob rau hauv cov ntaub ntawv ntawm kev kho mus sij hawm ntev nrog cov tshuaj no, kuj tsis tshwm sim.
Sydnopharm ntsiav tshuaj: cov lus qhia rau kev siv
Cov tshuaj yog siv rau hauv cov tshuaj hauv qab no:
1. Rau kev pab thiab tiv thaiv angina tawm tsam.
2. Nrog myocardial infarction nyob rau theem ntawm stabilization ntawm hemodynamic tsis.
3. Nrog rau qhov tsis txaus ntawm sab laug ventricle ntawm lub plawv hauv daim ntawv mob.
4. Nrog nce siab nyob rau hauv lub pulmonary voj voog ntawm cov ntshav khiav.
5. Nrog mob plawv tsis ua hauj lwm.
Nyob rau tom kawg, muaj ib qho tshwj xeeb ntawm kev siv tshuaj "Sydnopharm". Cov lus qhia rau nws siv nyob rau hauv cov xwm txheej zoo li no yog cov kab mob uas yuav tsum tau noj ntau dua glycosides thiab diuretics ua ke nrog cov tshuaj qhia.
Yuav siv li cas
Yuav kom tsis txhob muaj teeb meem thiab noj ntau dhau, tsuas yog kws kho mob yuav tsum tau sau ntawv Sydnopharm. Cov lus qhia rau kev siv cov tshuaj no txiav txim siab nws siv hauv lub sijhawm lossis tom qab noj mov. Noj cov ntsiav tshuaj nrog dej kom ntau.
Txhawm rau tiv thaiv kev mob angina, cov tshuaj "Sydnopharm" tau muab 1-2 mg rau 4 mus rau 6 zaug hauv thawj hnub thiab thib ob ntawm kev kho mob, 2-4 mg yuav tsum tau noj 2-3 zaug. hauv txhua hnub tom ntej. Qee zaum cov koob tshuaj tau nce mus rau 6-8 mg lossis ntau dua, tab sis qhov siab tshaj plaws yog 12 mg.
Cov tshuaj yog txhaj ib tus zuj zus hauv txhua kis. Nwstus nqi yuav tsum tau kho yog nyob ntawm theem thiab hom kab mob, nrog rau cov tsos mob. Nyob ntawm tus kab mob no, lub sijhawm ntawm kev kho mob kuj tau sau tseg.
Side effects
Puas siv cov ntsiav tshuaj Sydnopharm muaj qhov tshwm sim tsis zoo? Cov lus qhia rau kev siv cov tshuaj qhia tau hais tias cov tshuaj yuav provoke qhov pib ntawm ib tug mob taub hau nyob rau hauv thawj theem ntawm nws cov thawj coj. Tom qab lub sijhawm luv luv, qhov kev xav ploj mus.
Tsis tas li ntawd, thaum siv cov tshuaj "Sydnopharm", qhov txo qis hauv cov ntshav siab tuaj yeem ua tau, qee zaum mus rau qhov tawg. Qee zaus, muaj kev qeeb hauv lub cev muaj zog thiab kev puas siab puas ntsws. Cov yam ntxwv ntawm cov tshuaj no thaum siv nws yuav tsum raug coj mus rau hauv tus account los ntawm cov neeg tsav tsheb thiab cov neeg ntawm lwm txoj haujlwm uas xav tau kev xav thiab kev txiav txim siab ceev hauv chaw ua haujlwm.
Ntawm lwm yam, vim yog siv cov ntsiav tshuaj Sydnopharm (cov neeg mob tshuaj xyuas kom paub meej cov ntaub ntawv), cov kev mob tshwm sim xws li xeev siab, khaus, kiv taub hau, tawv nqaij pob khaus thiab lwm yam kev tsis haum tshuaj tuaj yeem pom.
YContraindications
Pathologies uas siv cov tshuaj "Sydnopharm" yog contraindicated:
- mob hnyav ntawm myocardial infarction;
- glaucoma (tshwj xeeb yog lub kaum sab xis);
- craniocerebral, arterial hypertension;
- vascular collapse;
- kev mob plawv ntawm lub hlwb;
- cev xeeb tub (thawj lub hlis twg) thiab lactation;
- laus;
- tus neeg intolerance rau tshuaj.
Kev sib tham nrog lwm yam tshuaj
Puas tso cai siv cov ntsiav tshuaj nrog lwm cov tshuaj thaum lub sijhawm kho
Sydnopharm? Cov lus qhia rau kev siv cov tshuaj hais tias cov tshuaj yuav siv tau ib txhij nrog calcium antagonists thiab beta-adrenergic blockers.
Thaum siv cov tshuaj "Sydnopharm" rau cov hom phiaj tshuaj, nws yog ib qho tsim nyog yuav tsum tau tshem tawm tag nrho cov ingress ntawm cawv rau hauv lub cev.
Txoj kev siv tshuaj
Thaum twg kuv yuav tsum siv Sydnopharm nrog ceev faj heev? Cov lus qhia rau nws siv piav qhia tias ib tug yuav tsum ceev faj txog qhov tsis pom qhov tshwm sim ntawm lub cev rau cov tshuaj nyob rau hauv cov ntaub ntawv ntawm impaired ntshav ncig ntawm lub paj hlwb, muaj zog intracranial siab, nrog arterial hypotension, glaucoma, thiab kuj nyob rau hauv lub sij hawm tom qab hemorrhagic stroke. los yog tom qab myocardial infarction.
Cov neeg laus uas muaj lub raum lossis lub siab tsis ua haujlwm yuav tsum haus cov tshuaj Sydnopharm yam tsawg kawg nkaus. Cov lus qhia rau kev siv tshuaj kuj ceeb toom tias cov xim E110, uas muaj nyob rau hauv cov tshuaj no, tuaj yeem ua rau muaj kev tsis haum tshuaj.
Thaum cev xeeb tub, nws yuav tsum ua tib zoo txheeb xyuas qhov piv ntawm kev pheej hmoo rau tus menyuam hauv plab thiab muaj txiaj ntsig zoo rau leej niam uas xav tau ua ntej pib kho nrog Sydnopharm. Kev siv cov tshuaj thaum lub sij hawm lactation yog nruj me ntsis contraindicated. Yog thovtshuaj yog ib qho tseem ceeb rau lub sij hawm no, ces yuav tsum tsis txhob pub mis niam. Cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo kuj raug txwv tsis pub siv cov tshuaj no.
Ntau tshaj
Dab tsi yog qhov tshwm sim thaum noj cov ntsiav tshuaj Sydnopharm ntau dhau? Ua ntej ntawm tag nrho cov, qhov no yog fraught nrog ib tug ntse txo nyob rau hauv cov ntshav siab. Qhov no ua rau kiv taub hau, xeev siab, ntuav.
Kev kho mob ntau dhau yog nyob ntawm cov tsos mob. Ib qho yuav tsum tau ua ua ntej yog kev ntsuas txhawm rau txhawm rau ntxuav lub cev sai ntawm cov tshuaj "Sydnopharm" - yuam diuresis los yog plab hnyuv.
Ib daim foos
Sydnopharm yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm 4 mg lossis 2 mg, ntxiv rau hauv daim ntawv ntawm cov tshuaj ntev-tso tawm ntawm 8 mg. Cov tshuaj yog ntim rau hauv daim hlau contour cellular. Txhua ntawm lawv muaj 10 ntsiav tshuaj. Cov ntaub ntawv tau ntim rau hauv cov thawv ntawv ntawm 3 daim (ib lub thawv muaj 30 ntsiav tshuaj).
Storage condition
Sydnopharm ntsiav tshuaj yog cov tshuaj muaj zog. Lawv yuav tsum khaws cia tsis pub ntau tshaj peb xyoos nyob rau hauv qhov chaw txias, qhuav ntawm qhov ncav cuag cov menyuam yaus, ntawm qhov kub ntawm 15 txog 25ºС.
Composition
Cov khoom xyaw tseem ceeb hauv Sydnopharm yog molsidomine. Cov koom haum pabcuam ntawm cov tshuaj muaj xws li Avicel PH 101, mint roj, starch, hydroxypropyl methylcellulose, lactose, magnesium stearate, aerosil 200,mannitol.
Analogues
Kuv puas tuaj yeem hloov cov ntsiav tshuaj Sydnopharm nrog lwm cov tshuaj? Analogues ntawm cov tshuaj no muaj. Cov no suav nrog cov tshuaj "Dilasid", "Corvamin" thiab "Corvaton". Cov yam ntxwv ntawm txhua tus muaj nyob hauv qab no.
Tshuaj "Dilasidom" ("Dilasidom"). Ua nyob rau hauv teb chaws Poland. Nws cov tshuaj nquag yog, xws li hauv Sidnopharm, molsidomine (molsidomine). Raws li kev faib tawm anatomical-therapeutic-chemical (ATC), cov tshuaj "Dilasid" yog hais txog peripheral vasodilators siv los kho cov kab mob plawv thiab cov tshuaj antianginal.
Means "Corvamin" ("Corvamin"). Ua nyob rau hauv Netherlands. Cov tshuaj nquag ntawm cov tshuaj kuj yog molsidomine. Raws li ATC kev faib tawm, cov tshuaj "Corvamin" yog hais txog cov tshuaj antianginal thiab peripheral vasodilators, uas yog siv los kho cov kab mob plawv.
Cov tshuaj "Corvaton". Ua nyob rau hauv lub teb chaws Yelemees. Lub luag haujlwm tseem ceeb ntawm cov tshuaj no yog, zoo li lwm cov analogues ntawm Sidnopharm ntsiav tshuaj, molsidomine. Raws li ATC kev faib tawm, cov tshuaj "Corvaton" suav nrog hauv pab pawg ntawm cov tshuaj antianginal thiab peripheral vasodilators, uas yog siv los kho mob plawv.
Tsis muaj qhov xwm txheej twg nws pom zoo kom siv cov ntsiav tshuaj Sydnopharm lossis lawv cov analogues yam tsis muaj kws kho mob cov tshuaj. Kev noj tshuaj rau tus kheej tuaj yeem ua rauirreversible tsis zoo txim. Nws tseem raug txwv nruj kom hloov cov koob tshuaj thiab lub sijhawm ntawm kev kho mob, raws li koj tus kheej xav, yam tsis tau sab laj nrog kws kho mob.
