Muaj tsawg tus neeg xav tias cov kab no yog cov kab zoo. Nyob rau hauv lub caij ntuj sov lawv tshwm, feem ntau nyob rau hauv cov huab cua kub. Wasps tsis tuaj yeem ya dhau cov khoom qab zib. Lawv mob heev. Yog hais tias ib tug neeg laus raug tom los ntawm ib tug Wasp, ces nws yuav muaj kev tsis haum tshuaj. Tab sis muaj ib qho txiaj ntsig zoo heev los ntawm lawv. Cov venom ntawm qee qhov wasps muaj zog tiv thaiv qog noj ntshav. Cov cuab yeej no muaj cov tshuaj lom ntawm Brazilian wasp. Cov kws tshawb fawb tab tom nrhiav kev txhim kho kev kho mob qog noj ntshav tsis tau.
Nyob Zoo Tshuaj
Brazilian wasp venom sai sai no yuav dhau los ua tshuaj tshiab hauv kev tawm tsam mob qog noj ntshav. Tsis ntev los no, nws tau pom tias cov tshuaj lom ntawm cov no tshwj xeeb wasps muaj xws li cov cuab yeej kho. Lawv nyob hauv Brazil nkaus xwb. Cov kab hauv qab yog cov tshuaj lom tsis muaj tshuaj lom rau txhua qhov chaw cuam tshuam.
Polybia Paulista wasp venom muaj Polybia-MP1 peptide. Nws ua rau qee qhov chaw ntawm lub cev cuam tshuam los ntawm malignant neoplasm. Ua ntej ntawm tag nrho cov, cov no yog cov qog nqaij hlav qog nqaij hlav prostate, leukemia, thiab cov qog nqaij hlav ntawm lub zais zis. Cov malignant neoplasms no tiv taus heevntau yam tshuaj.
Brazilian tus kab mob
Tus Brazilian wasp lossis polystyna belongs rau subfamily ntawm kev sib raug zoo, lossis ntawv wasps. Wasps ntawm genus Polybia muaj tus cwj pwm nyuaj heev. Lawv tsim ntau ntau yam honeycombs nrog suav tsis txheeb tawm mus rau sab nraud. Cov neeg ua haujlwm wasps nyob hauv cov combs. Lawv nrhiav tau los ntawm ib tug poj niam. Lawv nyob hauv qhov chaw sov sov ntawm South America. Lawv nyob hauv Brazil. Brazilian wasp venom pab tua mob qog noj ntshav.
Txoj kev tshuaj lom
Cov kws tshawb fawb los ntawm University of Leeds, uas nyob hauv tebchaws Askiv, tau paub ntev tias cov peptide tuaj yeem rhuav tshem cov qog nqaij hlav. Yog li ntawd, lawv tau koom nrog kev tshawb fawb tob txog qhov venom ntawm Brazilian wasp. Paul Beals thiab lwm tus kws tshawb fawb Askiv tau nkag siab tias yog vim li cas thiaj li muaj qhov tshwm sim zoo li no rau cov kab mob venom. Cov tshuaj lom peptides MP1 cuam tshuam zoo nrog lipids - fatty acids uas muab cov hlwb nrog lub zog thiab tsim cov membranes ntawm cov hlwb noj qab haus huv. Cov venom ntawm Brazilian wasp tua cov qog nqaij hlav cancer los ntawm kev tawm tsam cov kab mob sab sauv thiab tsim cov txiav hauv nws, los ntawm cov qog hlwb tuaj yeem cuam tshuam nrog cov neeg noj qab haus huv thiab muab cov pa oxygen. Nyob rau tib lub sijhawm, tsis muaj kev puas tsuaj rau lub cev ua haujlwm li qub. Qhov txawv yog tias nyob rau hauv lub cell noj qab haus huv, lub puab txheej muaj phosphatidylserine thiab phosphatidylethanolamine, thaum nyob rau hauv ib tug mob qog noj ntshav, nws ua raws li ib tug txheej txheej.
tshuaj tshiab
Tus nqi ntawm qhov qhib ntawm qhov hws, uas yog tsim los ntawm kev raug rau cov tshuaj lom ntawm Brazilian wasp, yog me me heev. Tab sis qhov no txaus rau RNA molecules thiab proteins mus dhau txheej txheej ntawm cov qog nqaij hlav cancer.
The British Biophysical Journal tau luam tawm ib tsab xov xwm ntawm lub ncauj lus "Kev kho los ntawm tus kab mob Brazilian wasp", uas tau luam tawm los ntawm Paul Beals. Nyob rau hauv nws, nws piav qhia txog yuav ua li cas venom venom tua cov qog nqaij hlav cancer. Raws li cov kws tshawb fawb, kev tshawb fawb tob txog nws cov muaj pes tsawg leeg yuav ua rau nws muaj peev xwm siv tshuaj los ntawm tshuaj lom hauv tshuaj rau cov kab mob oncological.
Kuaj los ntawm kev paub
Kom sim lawv qhov kev xav, cov kws tshawb fawb tau ua cov kev tshawb fawb sim. Txhawm rau ua qhov no, lawv tau tsim cov qauv cell membrane uas muaj phosphatidylserine thiab phosphatidylethanolamine. Lub membrane tau raug rau MP1 peptide. Ces lawv pib soj ntsuam cov nyhuv. Cov kws tshawb fawb tau paub dhau los tau pom tias muaj cov phosphatidylserine tivthaiv pab cov Brazilian wasp venom ua rau ntawm cov cell membrane, thiab kev sib xyaw ntawm phosphatidylethylamine tivthaiv nrog cov kab mob Wasp venom rhuav tshem cov txheej txheej sab sauv ntawm tes thiab ua rau cov microcracks me me hauv nws. Los ntawm cov micropores, cov cell cuam tshuam pib ua haujlwm ib txwm.
Txoj kev hloov pauv
Nyob rau yav tom ntej, cov kws tshawb fawb npaj los kawm kom paub meej txog cov txiaj ntsig ntawm cov kab mob venom peptide ntawm cov cell membrane cuam tshuam los ntawm kev mob qog noj ntshav. Lawv xav muab cov txiaj ntsig zoo no ntau zaus. Tsim kom muaj zog kho mob qog noj ntshav los ntawm tus kab mob ntawm tus kab mob Brazilian waspkev txiav txim thiab ib daim ntawv tshiab ntawm kev nyab xeeb tshuaj tiv thaiv kab mob. Qhov no yuav muaj txiaj ntsig zoo rau cov neeg mob qog noj ntshav.
Ib txoj hauv kev kho kom zoo hauv kev tawm tsam kev loj hlob ntawm cov qog nqaij hlav cancer yuav yog qhov zoo ntxiv rau txoj hauv kev xws li xov tooj cua thiab kws khomob, uas tua tsis tau tsuas yog cov kab mob qog noj ntshav xwb, tab sis kuj muaj cov hlwb noj qab haus huv tag nrho.
