Cricoid (los yog cricoid) mob qog noj ntshav yog ib qho mob qog nqaij hlav hauv plab, uas nyob rau qib thib ob ntawm tag nrho cov qog nqaij hlav hauv plab. Thawj yog gastric adenocarcinoma.
Thaum tus kab mob cuam tshuam rau ib feem ntawm lub plab zom mov, ces cov qog loj hlob, kis mus rau tag nrho nws cov txheej txheem. Qhov no neoplasm yog heev malignant. Metastases sai sai tshwm sim hauv lwm lub cev.
Kev piav qhia kab mob
Muaj kev hloov pauv tshwj xeeb ntawm cov qog nqaij hlav qog noj ntshav hauv tus kab mob no, los ntawm lub npe "ntiv nplhaib-hlwb mob qog noj ntshav" los ntawm. Atypical hlwb uas sau cov glandular epithelium sau ib yam khoom xws li mucin. Cov tshuaj no nyob rau hauv ib txwm muaj peev xwm tiv thaiv cov hlwb los ntawm cov kab mob, tab sis nws yuav tshwm sim tias muaj mucin ntau dhau. Yog li ntawd, lub cell nucleus yuav compressed, thiab nws yuav txav mus ze rau lub plhaub. Thaum histology ua tiav, cov qog nqaij hlav qog nqaij hlav atypical pom nyob rau hauv daim ntawv ntawm lub nplhaib.
Cricoid gastric cancer yog mob qog noj ntshav uas yog tus yam ntxwv ntawm endophytickev loj hlob. Muaj kev sib kis ntawm cov hlwb atypical sab hauv, thaum cov mucous, ces cov nqaij mos thiab cov serous txheej ntawm lub cev raug ntes.
Kev loj hlob ntawm neoplasm yog nqa tawm tsis yog nyob rau hauv qhov tob, tab sis kuj nyob rau hauv dav, vim lub qog tsis muaj ib tug meej ciam teb. Yog vim li ntawd nws nyuaj heev rau xaiv txoj kev kho kom zoo.
Cov qog nqaij hlav sai sai kis mus rau hauv lub cev los ntawm cov kua dej lymphatic. Yuav luag ib nrab ntawm cov neeg mob uas kuaj pom lub nplhaib cell carcinoma muaj cov qog loj hlob hauv txhua txheej ntawm lub plab. Hom mob qog noj ntshav no kho tau, tab sis tsuas yog kuaj pom ntxov, ua ntej metastases tshwm sim.
mob qog noj ntshav no feem ntau tshwm sim hauv cov poj niam hluas. Oncologists tsis tuaj yeem piav qhia txog qhov no.
Qhov laj thawj tseem ceeb
Ricoid cell carcinoma ntawm lub plab tshwm sim rau tib yam vim li cas lwm hom mob qog noj ntshav. Ntawm no, kev ua txhaum ntawm kev noj haus thiab khoom noj khoom haus tsis zoo muaj feem cuam tshuam rau lub plab. Cov yam pheej hmoo suav nrog:
- kev nyiam tshwj xeeb rau ntsim, ntsev, haus luam yeeb, pickled thiab tob kib zaub mov;
- noj tsis tu ncua, zaub mov qhuav, zaub mov txias lossis kub dhau;
- haus ntau dhau.
Txhua yam no tas li ua rau lub plab zom mov, cov qauv ntawm cov hlwb hloov pauv, lawv txoj haujlwm cuam tshuam. Vim li no, cov qog nqaij hlav cancer tsim los ntawm cov hlwb ib txwm.
Ntxiv rau cov khoom noj khoom haus, muaj ntau yam ua rau mob qog noj ntshav hauv plab:
- kev hloov pauv -oncologists tau lees paub qhov tseeb ntawm kev loj hlob ntawm hom mob qog noj ntshav hauv cov neeg mob uas cov txheeb ze muaj oncology;
- kuaj xyuas Helicobacter pylori hauv cov kua txiv hmab txiv ntoo - nrog rau qhov no, muaj qhov mob tsis tu ncua ntawm cov mucous ntawm lub plab, uas ua rau muaj kab mob ntev, tom qab ntawd mob qog noj ntshav;
- qhov muaj cov neeg nyob tsis zoo - yog tias qee cov tshuaj muaj nyob rau hauv cov av txheej (thiab qhov no tshwm sim hauv qee thaj tsam ntawm peb lub tebchaws), ces cov tshuaj carcinogenic sib sau hauv cov nroj tsuag uas tus neeg noj;
- tus cwj pwm phem - tsis yog cawv xwb, tab sis kuj haus luam yeeb tuaj yeem ua rau mob qog noj ntshav (tshwj xeeb tar decomposes, tom qab uas muaj cov carcinogenic ntau tsim, thiab lawv cuam tshuam rau tag nrho lub cev thiab lub cev ntawm lub cev).
Tsis tas li ntawd, ib tus neeg tuaj yeem tsim tus mob precancerous. Qhov no tuaj yeem txaus ntshai heev.
Cov mob Precancerous muaj xws li muaj cov polyps hauv plab, dysplasia, atrophic gastritis. Cov kab mob no yuav tsum tau kho, txwv tsis pub muaj kev pheej hmoo ntawm lawv hloov mus ua mob qog noj ntshav.
Tus kab mob tshwm sim li cas?
Ntau tus kab mob tsis tshwm sim nws tus kheej nyob rau hauv thawj ob theem. Yog vim li cas lub nplhaib cell carcinoma ntawm lub plab yog pom nyob rau theem 3 thiab 4th. Cov tsos mob tshwm sim thaum lub qog loj hlob hauv qhov dav thiab qhov tob.
Cov cim tseem ceeb ntawm hom mob qog noj ntshav:
- nrawm nrawm tom qab noj mov, hnyav hauv plab vim o;
- tshwm sim xeev siab, ntuav, tsam plab, raws plab, cem quav;
- cua txias, nquagmob plawv;
- Nyob tas li, tsaug zog;
- nce lub cev kub.
Y Kev zom zaub mov tsis zoo, metabolism cuam tshuam. Lub cev tsis muaj cov vitamins thiab minerals. Qib hemoglobin poob qis. Muaj plaub hau poob thiab dryness, tawv nqaij pallor, tsis muaj zog. Ib tug neeg muaj qhov mob tsis tu ncua hauv plab, uas tsis nyob ntawm kev noj zaub mov.
Nws muaj aversion rau nqaij thiab ntses tais. Nws yog vim li no hais tias muaj ib tug ntse yuag poob. Ib qho qog ntawm thaj tsam plawv ua rau dysphagia, uas yog, kev xav ntawm pob hauv caj pas. Yog tias cov hnyuv me raug cuam tshuam, peristalsis kuj tseem cuam tshuam. Yog tias cov qog loj dhau lawm, ces nws yuav ua rau muaj kev cuam tshuam tag nrho, uas yuav tsum tau muaj kev phais xwm txheej ceev.
Qee lub sij hawm mob qog noj ntshav, ces nws yog fraught nrog plab los ntshav. Kuj tseem muaj apathy, kev nyuaj siab, pw tsaug zog. Feem ntau qhov no tshwm sim nyob rau theem 3.
Thiab ua li cas theem 4 signet nplhaib cell carcinoma ntawm lub plab manifest nws tus kheej? Theem 4 yog tus cwj pwm los ntawm qhov tsis muaj qab los noj mov, cachexia hnyav, thiab ascites. Tus neeg mob feem ntau pw. Metastases tshwm sim hauv lwm lub cev, yog li lwm cov tsos mob koom nrog txhua yam, vim tias lub cev tseem ceeb tsis ua haujlwm li qub.
Stages
Muaj ntau theem ntawm kev mob qog noj ntshav cricoid:
- xoom - muaj cov qog nqaij hlav qog noj ntshav hauv cov txheej txheem ntawm lub plab;
- ua ntej - lub mucous membrane raug kev txom nyem;
- second - sab nraudtxheej;
- thib peb - cov qog kis mus rau txhua txheej thiab cov kabmob uas nyob sib ze (diaphragm, siab, ob lub raum, pancreas, peritoneum, spleen), lymph nodes raug cuam tshuam;
- thib plaub - foci kuj pom nyob rau hauv lub cev nyob deb.
Diagnosis
Kev kho kom ua tiav, nws yuav tsum ua raws sijhawm. Yog li ntawd, nws yog ib qho tsim nyog yuav tau mus ntsib kws kho mob ntawm thawj cov kab mob ntawm lub plab (mob, dyspepsia, hnyav, kub siab). Tsis tas li ntawd, nws tseem ceeb heev uas yuav tau mus kuaj mob raws sij hawm thiab kev kuaj xyuas tas li.
txhawm rau txheeb xyuas lub nplhaib cell carcinoma ntawm lub plab, koj yuav tsum:
- pub ntshav rau kev tshuaj ntsuam (xws li oncomarkers) - qhov no yog qhov mob hauv lub cev, tsis muaj hemoglobin, kuaj pom tsis ua haujlwm hauv lub plawv thiab daim siab;
- ua gastroscopy thiab simultaneous biopsy (tib lub sijhawm, lub raj nrog lub koob yees duab thaum kawg tau muab tso rau hauv lub plab, txhua qhov kev hloov pauv hauv cov mucosa pom meej meej, tom qab ntawd ib daim me me tshwj xeeb plucked tawm rau histology);
- ua ib qho kev kuaj ultrasound ntawm peritoneum - nws tso cai rau koj txheeb xyuas qhov mob thiab mob qog nqaij hlav thib ob;
- nqa x-ray nrog tus neeg sawv cev sib txawv kom pom cov kev hloov hauv plab;
- ua kev suav tomography, ua tsaug rau qhov no, kuaj pom metastases thiab thaj tsam ntawm cov txheej txheem malignant hauv lub cev tau txiav txim siab.
Ricoid cell carcinoma ntawm plab: kev kho mob
Kev kho rau hom mob qog noj ntshav no yog phaiskev khiav hauj lwm kom tshem tawm cov qog nws tus kheej, ib feem ntawm lub plab, lymph nodes. Nyob rau theem kawg ntawm tus kab mob, qhov tseem ceeb thib ob kuj raug tshem tawm. Tom qab ntawd cov kws khomob tau sau tseg. Nws tuaj yeem raug sau ua ntej kev phais, uas tuaj yeem ua rau txo qis hauv thaj tsam ntawm cov txheej txheem malignant. Qhov no yog qhov tseem ceeb hauv kev kuaj mob ntawm "ntiv nplhaib-cell carcinoma ntawm lub plab." Cov kws khomob tomqab phais txhim kho qhov kev mob tshwm sim. Microscopic foci ntawm mob qog noj ntshav raug rhuav tshem hauv txoj kev no tau zoo heev.
Tsis tas li, kev kho mob palliative nrog tshuaj tiv thaiv kab mob yog siv los txo tus neeg mob tus mob. Yog li koj thiaj ua tau nws lub neej ntev.
Kev kho hluav taws xob tsis tshua siv. Qhov chaw ntawm cov txheej txheem malignant loj dhau rau irradiation. Nrog kev pab los ntawm kev npaj tshwj xeeb, lawv txo qhov mob, txhim kho txoj hnyuv, tiv thaiv lub plawv thiab ob lub raum.
Nov yog li cas RCC tau kho hauv tsev kho mob.
Lub neej kwv yees
Hom mob qog noj ntshav no muaj qhov hnyav hnyav nrog qhov tsis zoo. Thiab tsuas yog kev tshawb pom ntxov, nrog rau kev kho raws sijhawm, yuav tso cai rau muaj sia nyob rau 5 xyoos tom qab kev phais. Qhov muaj feem muaj 85%.
Yog tias kuaj pom tus kab mob thib 3, ces qhov ciaj sia nyob rau 5 xyoos tsuas yog 40%. Lub sijhawm no, metastases tshwm sim hauv lwm yam kabmob, uas tsis tuaj yeem kov yeej los ntawm txoj kev kho niaj hnub no. Qhov no yog qhov txaus ntshai rau lub nplhaib cell carcinoma ntawm lub plab.
Qhov kev mob tshwm sim tom qab phais thaum kuaj pom tus kab mob nyob rau theem 4 yog qhov tsis zoo. Kev tuag feem ntau tuaj sai sai. Tab sis yog tias kev kho mob txhawb nqa tau ua tiav,yuav muaj peev xwm nyob tau ob peb hlis ntxiv nrog cricoid cancer ntawm lub plab. Nws muaj peev xwm ua neej nyob 5 xyoos tom qab kev phais, tab sis lub caij nyoog yog 5-10%.
Dr. Walllock cov lus qhia
Lub ntiaj teb nto moo Dr. Walllock thov kom kho lub nplhaib cell cancer ntawm lub plab nrog kev pab ntawm kev noj zaub mov. Nws pom zoo suav nrog beta-carotene, vitamin E thiab cov kab mob selenium hauv kev noj haus. Qhov no yuav pab tau, hauv nws txoj kev xav, txo cov neeg tuag los ntawm kev mob qog noj ntshav. Kev noj zaub mov muaj zog tuaj yeem kho thiab tiv thaiv ntau yam kab mob txaus ntshai.
Zoo kawg
khoom noj khoom haus puv thiab noj qab haus huv yog tus yuam sij rau lub neej ntev. Nws tseem yog qhov tsim nyog kom txo qis txhua tus cwj pwm phem. Qhov no yog tshwj xeeb tshaj yog muaj tseeb rau cov neeg uas muaj ib tug hereditary predisposition. Yog tias muaj cov kab mob ntev ntawm txoj hnyuv, nws yog ib qho tsim nyog yuav tau kho lawv, nrog rau kev tshuaj xyuas prophylactically (tsawg kawg ib xyoos ib zaug). Thiab tsis txhob cia siab rau lwm txoj kev kho mob rau RCC.
