Androgens - yog dab tsi? Nws yog ib qho tsim nyog sau cia tias qhov no yog lub npe nrov rau tag nrho cov pab pawg hu ua steroid hormones, uas yog tsim los ntawm cov gonads (rau cov poj niam - lub zes qe menyuam, rau cov txiv neej - noob qes) thiab adrenal cortex.
Ib qho ntawm cov tshuaj hormones tseem ceeb ntawm pawg no yog testosterone. Thaum nug cov lus nug ntawm androgens - nws yog dab tsi, feem ntau ntawm peb tam sim ntawd los txog lub npe ntawm cov tshuaj no. Nws cuam tshuam ntau cov ntaub so ntswg ntawm tib neeg lub cev. Ib qho ntawm cov laj thawj rau qhov dav dav ntawm kev ua yog tias testosterone tuaj yeem hloov mus rau lwm cov tshuaj hormones - estradiol thiab dihydrotestosterone. Qhov no yog txheej txheem nthuav dav heev. Yog li peb tuaj yeem hais tau nyab xeeb: testosterone yog cov tshuaj hormones tseem ceeb ntawm pawg xws li androgens.
Testosterone yog dab tsi? Ntau precisely, qhov tseeb yog nws tsim, dab tsi cuam tshuam rau tib neeg lub cev tag nrho? Testosterone yog tsim nyob rau hauv daim siab nrog rau etiocholanol thiab androsterone. Nws yuav tsum raug sau tseg tias dihydrotestosterone hloov mus rau peb lwm yam tshuaj hormones. Nws cuam tshuam rau ob qho tib si kev xav ntawm ib tug neeg (piv txwv li, theem ntawm aggressiveness) thiab kev ua plees ua yi. Nws kuj pabqee qhov kev pab cuam rau kev tswj cov metabolism. Raws li qhov tseeb, cov txheej txheem no ua tsis tau yog tsis muaj nws.
Androgens - yog dab tsi? Qhov no yog lub npe ntawm txiv neej cov tshuaj hormones uas muaj steroid xwm. Lawv muaj kev cuam tshuam loj heev rau kev loj hlob ntawm kev sib deev theem nrab cov yam ntxwv, nrog rau kev txhawb nqa kev ua haujlwm ntawm cov txiv neej hauv nruab nrog cev. Tab sis lawv txhawb ntau lwm cov txheej txheem biochemical uas tsis cuam tshuam txog poj niam txiv neej. Vim tias cov tshuaj hormones no, cov teebmeem anabolic tuaj yeem pom, lawv hloov pauv cov metabolism ntawm lipids, carbohydrates thiab roj cholesterol. Kuv xav kom nco ntsoov tias qee theem ntawm androgens kuj muaj nyob rau hauv poj niam lub cev yam tsis tau poob. Hauv cov ntxhais, nws tau qhia los ntawm androstenedione, dehydroepiandosterone thiab testosterone. Nws tshwm sim tias ntau dhau ntawm cov tshuaj hormones no pom nyob rau hauv cov poj niam, uas ua rau hyperandrogenemia, fertility yog impaired, thiab txawm infertility yuav tshwm sim.
Nws yuav tsum kov ntawm xws li qhov ntsuas ntawm androgens dawb. Qhov no yog chav tsev uas siv los ntsuas bioavailable testosterone. Qhov kev ntsuas no yog xam los ntawm kev suav lej nyuaj. Nws yog txiav txim los ntawm qhov sib piv ncaj qha ntawm qhov concentration ntawm tag nrho testosterone rau tus nqi ntawm kev sib deev-binding globulin.
Androgens yog cov tshuaj hormones muaj zog heev uas cuam tshuam rau synthesis ntawm cov proteins, inhibiting lawv kev puas tsuaj. Lawv kuj muaj cov nyhuv anti-catabolic lossis anabolic. Tsis tas li ntawd, lawv txo cov piam thaj hauv cov ntshavntshav. Thiab ib qho ntxiv nuance: lawv nce lub zog thiab cov leeg nqaij. Androgens tseem tuaj yeem pab txo qis cov rog subcutaneous tam sim no hauv lub cev. Androgens yog ib qho tseem ceeb ntawm txhua yam kab mob (ob leeg poj niam thiab txiv neej), lawv qhov tsis muaj lossis tsis txaus tuaj yeem ua rau muaj kab mob ntau.
