Piloid astrocytoma: cov tsos mob, kev kuaj mob, kev kho mob, kev tiv thaiv

Cov txheej txheem:

Piloid astrocytoma: cov tsos mob, kev kuaj mob, kev kho mob, kev tiv thaiv
Piloid astrocytoma: cov tsos mob, kev kuaj mob, kev kho mob, kev tiv thaiv

Video: Piloid astrocytoma: cov tsos mob, kev kuaj mob, kev kho mob, kev tiv thaiv

Video: Piloid astrocytoma: cov tsos mob, kev kuaj mob, kev kho mob, kev tiv thaiv
Video: PHYTO Education Video 2024, Kaum ib hlis
Anonim

Astrocytoma (piloid, glomerular, microcystic) yog ib qho neoplasm nyob hauv lub hlwb. Lub pathological mob ntawm lwm yam variants ntawm lub paj hlwb hlav yog feem ntau. Los ntawm sab hauv hauv lub neoplasm, feem ntau tuaj yeem txheeb xyuas cov cyst uas muaj kev loj hlob tseem ceeb. Ib qho astrocytoma tuaj yeem ua rau lub siab me ntsis ntawm cov ntaub so ntswg hlwb.

cov ntaub ntawv dav dav

Qee lub sij hawm ib tug piloid astrocytoma tsis ua malignant, tab sis malignancy yuav loj hlob. Qhov zoo tshaj plaws prognosis nyob rau hauv cov neeg mob raug kev txom nyem los ntawm ib tug benign daim ntawv, localized nyob rau hauv lub nkag tau mus rau qhov chaw. Muaj kev pheej hmoo ntawm cov qog tsim nyob rau hauv ib cheeb tsam uas tsis tuaj yeem nkag mus rau kev phais mob - cov kev xaiv no cuam tshuam nrog kev mob hnyav zuj zus, nrog rau cov tsos ntawm astrocytoma loj. Feem ntau, cov neeg mob uas muaj tus kab mob pathological tau kuaj pom thaum ntxov tuaj yeem xav tau qhov txiaj ntsig zoo dua.

Piloid astrocytoma ntawm lub hlwb - prognosis nyob rau hauv cov me nyuam
Piloid astrocytoma ntawm lub hlwb - prognosis nyob rau hauv cov me nyuam

Yog tias koj xav tias piloid astrocytoma ntawm vermis, hemispheres, cerebellum, koj yuav tsum hu rau lub chaw kho mob tshwj xeeb. Cov neeg mob uas muaj cov kev pab kho mob nyob rau hauv ib lub tsev kho mob niaj hnub, muaj cov cuab yeej zoo muaj peev xwm rov zoo. Ib qho tseem ceeb yog qhov tseeb ntawm kev kuaj mob.

Ntse ntawm pathology

Pyloid astrocytoma ntawm lub hlwb yog ib qho neoplasm ntawm hom glial. Lub hlwb tseem ceeb rau nws yog astrocytes, pom zoo li lub hnub qub, zoo ib yam li kab laug sab. Cov hlwb tseem hu ua neuroglial. Lawv lub luag haujlwm tseem ceeb yog txhawb nqa cov neurons, lub hlwb tseem ceeb. Kev thauj mus los ntawm cov khoom siv sib txuas los ntawm cov phab ntsa vascular mus rau neuron membrane nyob ntawm astrocytes. Cov qauv cellular koom nrog hauv kev loj hlob, kev loj hlob ntawm cov hlwb ntawm lub paj hlwb, thiab tseem txiav txim siab qhov muaj pes tsawg leeg ntawm cov kua dej ntawm cov hlwb.

Nyob hauv cov medulla dawb, piloid astrocytoma hauv cov menyuam yaus lossis cov neeg laus tuaj yeem tsim los ntawm fibrous-type astrocytes. Cells nyob rau hauv cov teeb meem grey yog protoplasmic. Ob hom no yog tsim los rau kev tiv thaiv neuronal tiv thaiv cov tshuaj lom neeg aggressive compounds, traumatic yam. Astrocytes xyuas kom cov neurons tau txais kev noj haus thiab tswj cov ntshav ntws hauv lub hlwb.

Cancer los tsis?

Anaplastic piloid astrocytoma, glomerular, microcystic - txhua yam ntawm neoplasm hauv nqe lus nug tsis raug hu ua mob qog noj ntshav. Qhov no yog vim lub hauv paus hlwb los ntawm cov qog tsim - lawv tsis nyob rau hauv lub epithelium, tab sis muaj ib tug complex qauv. Cov txheej txheem malignant tsis tshua muaj nrog metastasis sab nraum lub hlwb, txawm hais tias hauv lub cev nws muaj peev xwm tsim tau ntau foci ntawm atypical hlwb coj los ntawm cov ntshav ntws los ntawm lwm cov ntaub so ntswg thiab kabmob. Ib tug malignant neoplasm feem ntau indistinguishable los ntawm ib tug benign ib tug, thiab ua kom tiav kev tshem tawm yog nyuaj vim tsis muaj tus ciam teb du.

Pyloid astrocytoma ntawm lub hlwb, prognosis
Pyloid astrocytoma ntawm lub hlwb, prognosis

Kev kuaj mob hauv piloid astrocytoma yog qhov hnyav zuj zus vim qhov muaj cov ntshav-hlwb teeb meem, uas yog insurmountable rau feem ntau cov tshuaj tiv thaiv kab mob. Tshwj xeeb tshaj yog muaj zog hauv lub hlwb tiv thaiv kab mob txwv tsis pub muaj peev xwm ntawm kev kho mob, thaum cov txheej txheem qog tuaj yeem txhim kho hauv txhua qhov chaw ntawm lub cev. Ntau qhov xwm txheej tau paub thaum lub cev tseem ceeb ntawm cov qog tau tsim nyob rau hauv ib feem, thiab cov hlwb atypical tau nyob hauv ntau lwm tus.

Txoj kev ntawm rooj plaub

Muaj peev xwm tsim ntawm polyclonal formations. Lo lus no yog hais txog lub qog nyob rau hauv ib lub qog. Lub npe yog siv rau cov txheej txheem qog nqaij hlav. Cov chav kawm kho mob suav nrog kev siv cov tshuaj complex, txij li ib qho ntawm cov qog feem ntau nkag siab rau qee cov tshuaj uas muaj kev nyab xeeb rau cov qog thib ob, thiab rov ua dua.

Piloid astrocytoma ntawm cerebellum, vermis thiab lwm qhov ntawm lub hlwb yog kho qhov teeb meem, thiab kev vam meej ntawm cov chav kawm tsis tas li nyob ntawm cov yam ntxwv histological ntawm kev tsim. Feem ntau lub luag haujlwm tseem ceeb yog ua los ntawm qhov nuances ntawm qhov chaw, qhov ntev ntawm thaj chaw atypical.

qhov teeb meem tuaj qhov twg?

Kev sim txheeb xyuas vim li cas piloid astrocytoma ntawm cerebellum tsim, hauv hemispheres thiab lwm qhov ntawm lub cev, tseem tsis tau ua tiav, thiab cov kws kho mob tsis tuaj yeem nkag siab tias dab tsi ua rau astrocytes rau tus cwj pwm atypical. Piv txwv li, qee qhov tsis zoo sab nraud nrog rau qib siab ntawm qhov tshwm sim tuaj yeem ua rau degeneration ntawm cellular qauv, tshwj xeeb tshaj yog tias lawv cuam tshuam ib txhij. Lub ntsiab yog suav tias yog ionizing hluav taws xob. Raws li kev cuam tshuam ntawm qhov xwm txheej no, nrog rau qib siab ntawm qhov tshwm sim, cov txheej txheem malignant tuaj yeem pib. Yog tias ib tus neeg tau txais kev kho mob uas suav nrog cov kab hluav taws xob, qhov kev pheej hmoo ntawm astrocytoma ntau zaus ntau dua.

Anaplastic piloid astrocytoma
Anaplastic piloid astrocytoma

Pyloid astrocytoma (zoo li lwm hom neoplasm) tuaj yeem tsim tawm tsam keeb kwm yav dhau los ntev ntev ntawm cov tshuaj lom neeg sib xyaw. Tej yam txaus ntshai yog txuam nrog kev ua haujlwm hauv cov chaw ua haujlwm, hauv thaj chaw muaj kev lag luam. Qee cov kab mob tuaj yeem ua rau lub cev degeneration. Qee qhov xwm txheej, tus kab mob cuam tshuam nrog cov yam ntxwv ntawm caj ces, hauv lwm tus, kev raug mob los ua qhov pib ntawm atypical txoj kev loj hlob. Nws paub tias qee yam ntau yam tau kuaj pom ntau dua hauv cov menyuam yaus, lwm tus hauv cov tub ntxhais hluas hnub nyoog qis dua 30 xyoo, tab sis kuj muaj cov qauv uas muaj ntau dua rau cov neeg laus.

Yuav ua li cas xav?

Piloid astrocytoma (los yog lwm hom qog) tuaj yeem xav tias muaj teeb meem nrog kev sib koom tes ntawm kev txav. Feem ntau, qhov no qhia tias muaj kev ua haujlwm tsis zoo hauv kev ua haujlwm ntawm cerebellum, thiab lawv tuaj yeem cuam tshuam nrog neoplasm. Feem ntau, cov tsos mobtxiav txim los ntawm ob yam: qhov chaw, qhov loj ntawm qhov chaw atypical. Astrocytoma tuaj yeem ua rau kev hais lus tsis zoo thiab lwm tus ua rau lawv tsis nco qab lossis tsis pom kev.

Piloid astrocytoma nyob rau sab laug ib nrab ntawm lub hlwb tuaj yeem ua rau tuag tes tuag taw ntawm lub cev sab xis. Feem ntau lub taub hau mob heev thiab tas li, rhiab heev raug mob. Ntau tus neeg mob tsis muaj zog, raug kev txom nyem los ntawm cov teeb meem hauv plawv: nce nrawm, fuzziness, tsis sib xws. Kev poob siab tuaj yeem ua tau. Yog hais tias lub qog nyob rau hauv lub caj pas pituitary, hypothalamus, lub endocrine system yuav cuam tshuam.

xwm txheej hloov tshiab

Txheeb xyuas cov qauv ntawm tes, ib tus tuaj yeem faib cov ntaub ntawv raws li protoplasmic, fibrillar, gemistocytic. Muaj piloid astrocytoma, kuj muaj glomerular, cerebellar cov ntaub ntawv. Kev soj ntsuam qib ntawm kev ua phem, txhua kis tau muab faib ua plaub qib.

Ntau txog hom

Kev kwv yees zoo rau piloid astrocytoma ntawm lub hlwb hauv cov menyuam yaus, yog tias tus kab mob yog thawj qib. Qhov no suav nrog cov txheej txheem benign. Cov kab mob hauv cheeb tsam maj mam nce qhov loj, tab sis cov txheej txheem qeeb qeeb. Qhov ntev ntawm thawj hom qog yog me me, thiab lawv tau muab cais los ntawm cov ntaub so ntswg noj qab haus huv los ntawm cov tshuaj ntsiav tshwj xeeb, uas yog vim li cas cov neeg mob feem ntau tsis tsim cov paj hlwb. Cov qog yog tsim los ntawm astrocytes, zoo li lub nodule nyob rau hauv tsos. Ntau zaus, qhov tsim tau raug kuaj pom hauv cov menyuam yaus.

Pyloid astrocytoma ntawm lub hlwb - tshuaj xyuas
Pyloid astrocytoma ntawm lub hlwb - tshuaj xyuas

Qib thib ob yog diffuse. Yog hais tias nrog piloid astrocytoma ntawm lub hlwbqhov kev kwv yees yog feem ntau kuj zoo, ntawm no qhov xwm txheej yog qhov nyuaj dua. Cov qog ua rau qeeb qeeb, thiab cov hlwb uas tsim nws txawv ntawm cov astrocytes zoo tib yam. Ntau zaus, qhov tsim tau pom hauv cov neeg mob hnub nyoog 20-30 xyoo.

Txuas ntxiv lub ntsiab

hom thib peb yog anaplastic. Nws yog tus cwj pwm los ntawm kev ua phem, qhia los ntawm kev loj hlob sai. Cells txawv heev ntawm cov uas noj qab nyob zoo. Malignancy raug ntaus nqi siab.

Pab pawg plaub yog glioblastomas. Cov hlwb ntawm cov neoplasms no txawv heev los ntawm cov qauv hlwb noj qab haus huv. Kev tsim tuaj yeem cuam tshuam kev ua haujlwm ntawm lub hlwb tseem ceeb. Nws yog tus cwj pwm los ntawm kev txhoj puab heev, kev loj hlob sai. Feem ntau, cov neeg mob siv tsis tau. Feem ntau, glioblastoma raug kuaj pom nyob rau hauv lub paj hlwb hemispheres, cerebellum, thiab thalamus, uas yog lub luag haujlwm rau kev faib cov ntaub ntawv los ntawm cov txheej txheem peripheral. Qhov tseem ceeb tshaj plaws nrog piloid astrocytoma ntawm lub hlwb, qhov kev tshwm sim hauv cov neeg mob uas muaj glioblastoma, tshwj xeeb tshaj yog tias kev phais tsis tau.

Progress specifics

Yog tias kuaj pom ib qho neoplasm ntawm thawj, hom thib ob, qhov kev pheej hmoo ntawm cov qog degeneration yog siab, uas ua rau kev nce qib ntawm tus mob mus rau qib peb lossis plaub. Ntau zaus, malignancy ntawm cheeb tsam tshwm sim hauv cov neeg laus. Txawm li cas los xij, ntau cov lus teb los ntawm cov neeg mob, kev tshuaj xyuas kev kho mob ntawm cerebral piloid astrocytoma, diffuse qhia tias qhov kev pheej hmoo ntawm cov kab mob no yuav tsum tsis txhob kwv yees. Ib tug benign neoplasm tsis muaj tsawg txaus ntshai tshaj li ib tug reborn, yog li ntawd, raws li qhov kev kuaj mob tau qhia meej, nws yog ib qho tseem ceeb rau tam sim ntawd pib kho nyob rau hauv ib tug reborn.kev saib xyuas ntawm ib tus kws kho mob paub txog. Cov txiaj ntsig ntawm qhov kev kawm no yog txiav txim siab los ntawm qhov chaw ntawm kev tsim, nws qhov ntev, rhiab heev rau cov tshuaj niaj hnub.

Yuav ua li cas?

Cov kev kho mob hauv qhov xwm txheej tau kuaj pom astrocytoma yog xaiv raws li thaj chaw ntawm thaj chaw, qhov loj me, cov yam ntxwv ntawm cov qauv histological. Feem ntau, qhov kev cia siab yog zoo dua rau cov neeg mob hluas dua li cov laus, cov neeg mob uas tuaj yeem kho tau. Qhov txiaj ntsig zoo tshaj yog ua tau yog tias cov neoplasm raug tshem tawm tag.

Pyloid astrocytoma
Pyloid astrocytoma

Nyob rau theem thib peb ntawm tus kab mob, nrog rau kev degeneration ntawm piloid astrocytoma, kev sib koom ua ke ntawm kev kho mob yog xyaum. Tus neeg mob raug xa mus rau kev phais, muab ib qho kev pab cuam ntawm cov tshuaj thiab kev kho hluav taws xob. Qhov nruab nrab, nrog rau piloid astrocytoma degenerated rau hauv ib qho anaplastic astrocytoma tom qab phais, qhov kev cia siab rau kev ciaj sia yog peb xyoos. Qhov txiaj ntsig zoo tshaj plaws yog ua tau thaum muaj hnub nyoog me, yog tias ua ntej pathology lub xeev ntawm lub cev tau zoo, kev noj qab haus huv muaj zog, thiab cov hlwb atypical raug tshem tawm tag nrho.

Daim ntawv piloid ntawm tus kab mob no feem ntau kuaj pom hauv cov menyuam yaus, nws loj hlob tsawg. Ntau zaus, qhov kev cia siab yog qhov zoo, txij li qhov tsim yog tus cwj pwm los ntawm kev pheej hmoo ntawm malignancy. Cov chav kawm kho mob suav nrog kev tshem tawm tag nrho cov hlwb txaus ntshai, tab sis qhov no tsis yog ib txwm muaj. Yog hais tias cov qog tau tsim nyob rau hauv lub paj hlwb qia, hypothalamus, kev phais yuav tsis ua tau. Astrocytoma nyob rau hauv lub hypothalamus yog nquag mus rau metastasis.

Kev teem sijhawm rov ua haujlwm: dab tsi ntxiv?

Qhov tshwm simKev ua haujlwm yog txiav txim siab loj los ntawm qhov loj ntawm neoplasm thiab cov yam ntxwv ntawm nws qhov kev tshem tawm, nrog rau thaj chaw uas cov qog nyob. Yog hais tias ib tug piloid astrocytoma tau tsim nyob rau hauv ib qho chaw nkag tau ntawm lub hlwb, qhov kev tshwm sim kuj zoo, thiab lub neej expectancy yog ntev. Qhov xwm txheej phem dua yog tias astrocytoma tshwm sim hauv ib feem ntawm lub cev tsis tuaj yeem nkag mus rau tus kws phais.

Nws tsis yog qhov tsis yooj yim rau astrocytoma rov zoo tom qab kev phais. Raws li txoj cai, yog tias qhov no tshwm sim, tom qab ntawd hauv thawj ob xyoos tom qab ncua kev tshwm sim. Qhov kev kwv yees zoo dua yog tias astrocytoma tuaj yeem kuaj pom sai li sai tau thaum nws nyuam qhuav tsim. Yog hais tias kev kho mob ntawm benign neoplasm tsis pib raws sijhawm, nrog qhov tshwm sim ntawm 70% nws yuav rov tsim dua lub sijhawm.

CyberKnife

Tam sim no, cov thev naus laus zis no suav tias yog ib qho ntawm cov kev vam meej tshaj plaws, yog siv zog thaum nws tsim nyog los ua haujlwm ntawm tus neeg mob uas raug mob los ntawm astrocytoma. Txoj kev pab kom tshem tau cov qog nqaij hlav hauv qhov chaw nyuaj. Txoj kev siv thev naus laus zis ntawm kev tshem tawm tsis sib cuag tau siv rau ntau xyoo thiab tau ua pov thawj nws txoj kev ntseeg siab hauv neoplasms ntawm qhov chaw sib txawv. Muaj tseeb tiag, cov txheej txheem no yuav raug nqi ntau, thiab tsis yog txhua lub tsev kho mob muaj cov cuab yeej tsim nyog rau CyberKnife.

Pyloid astrocytoma tsis ua malignant
Pyloid astrocytoma tsis ua malignant

Yog hais tias kev phais classical contraindicated, radiosurgery yuav tsum tau txiav txim siab rau astrocytoma - tej zaum qhov no yog txoj kev uas yuav cawm tau txoj sia. Txoj kev tshwj xeeb pab xa cov koob tshuaj nce ntxivionizing hluav taws xob ncaj qha mus rau thaj tsam ntawm cov hlwb txawv txav, tsis muaj teeb meem nyob ib puag ncig cov qauv kev noj qab haus huv.

Ntawm ntawm radiosurgery

Txoj hauv kev cuam tshuam nrog kev txwv nruj ntawm cov tshuaj tiv thaiv hluav taws xob. Ib lub tswv yim xaiv kom raug yog tus yuam sij rau kev ua tiav kev puas tsuaj ntawm cov txheej txheem pathological, thaum tsis ua mob rau lwm qhov chaw thiab cov kabmob ntawm lub cev. Qee qhov xwm txheej, kev phais hluav taws xob tsis tas yuav tsum tau mus pw hauv tsev kho mob - qhov xwm txheej sab nraud txaus. Regenerative kauj ruam, tsis muaj kauj ruam rov qab.

Thawj theem ntawm txoj kev siv hluav taws xob ntawm kev phais mob suav nrog kev kuaj mob tus neeg mob, suav nrog CT thiab MRI cov duab. Tus kws kho mob tau txais daim duab peb sab ntawm thaj chaw pathological thiab cov yam ntxwv ntawm nws qhov chaw txheeb ze rau cov ntaub so ntswg noj qab haus huv. Tus kws kho mob lub cev thiab tus kws kho mob hluav taws xob tsim cov phiaj xwm kev cuam tshuam, xaiv cov koob tshuaj zoo tshaj plaws ntawm kev cob qhia tsim los ua kom qeeb thiab tiv thaiv kev loj hlob ntawm tes. Raws li txoj kev npaj tau pom zoo, thawj pawg neeg raug xaiv. Raws li txoj cai, chav kawm yuav kav ib mus rau peb cov txheej txheem.

Technical yam

Kev phais hluav taws xob tsis muaj mob, yog li tsis tas yuav tshuaj loog, tshuaj loog. Thaum lub sijhawm tshwm sim, tus neeg mob nco qab thiab tswj hwm nws tus kheej. Cov rooj zaum tshwj xeeb tau tsim. Cov khoom siv hluav taws xob yog muab los ntawm ib tus neeg siv khoom tshwj xeeb. Nyob nruab nrab ntawm ob kab teeb, lub cuab yeej ntsuas qhov teeb tsa, tsom mus rau cov ntsiab lus muab, uas tso cai rau koj los ua qhov kev cuam tshuam zoo heev. Lub khoos phis tawj tswj hwm cov koob tshuaj hluav taws xob uas muaj txiaj ntsig zoo tiv thaiv kab mob, tab sisnyab xeeb rau tib neeg.

Piloid astrocytoma ntawm cerebellum
Piloid astrocytoma ntawm cerebellum

Qee lub sij hawm tom qab ua tiav cov txheej txheem, koj yuav tau tuaj rau hauv tsev kho mob rau kev soj ntsuam xyuas. Kev kuaj mob yuav qhia tau tias qhov kev tshem tawm hluav taws xob tau zoo npaum li cas.

Zoo thiab phom sij

Yog tias kuaj pom astrocytoma, tsis txhob yig tiv tauj tus kws kho mob tshwj xeeb. Nws paub los ntawm kev txheeb xyuas kev kho mob tias nws yog cov txheej txheem qog nqaij hlav hauv lub hlwb uas muaj cov neeg tuag ntau tshaj plaws. Ntawm lwm cov neoplasms hauv lub hauv nruab nrab lub paj hlwb, yuav luag ib nrab yog astrocytomas ntawm ntau yam duab, thiab ntau zaus txiv neej dhau los ua neeg mob ntau dua li poj niam.

Kev ntsuas los tiv thaiv tus kab mob tseem tsis tau tsim, txij li cov laj thawj uas ua rau muaj kab mob tsis paub. Kev tiv thaiv tsis yog siv, tab sis kev pheej hmoo tuaj yeem txo los ntawm kev zam kev raug mob, raug, thiab tshuaj lom neeg.

Pom zoo: