Hauv kab lus, peb yuav txiav txim siab cov lus qhia siv rau Synflorix.
Qhov tseeb, cov tshuaj no yog ib pawg tshwj xeeb ntawm cov tshuaj tiv thaiv kab mob pneumococcal, ncaj qha rau hauv cov antigens ntxiv nrog cov protein D. Tsis tas li ntawd, Synflorix suav nrog antigens tshwj xeeb nrog kab mob diphtheria thiab tetanus toxoids. Nws yog ib qho tsim nyog sau cia tias qhov muaj pes tsawg leeg ntawm cov tshuaj tiv thaiv tshwj xeeb no kuj suav nrog 10 serotypes tam sim no ntawm Streptococcus pneumoniae chav kawm, ua tsaug rau qhov tshuaj tiv thaiv ua tau raws li tag nrho cov cai ntawm kev noj qab haus huv.
Cov tshuaj tiv thaiv no yog 10-valent pneumococcal polysaccharide tshuaj tiv thaiv, sib txuas nrog Haemophilus influenzae D-protein, diphtheria thiab tetanus toxoids, adsorbed los tiv thaiv kab mob pneumococcal. Synflorix yog tsim los ntawm Lavxias teb sab tuam txhab CJSC GlaxoSmithKline Trading.
Kev txhaj tshuaj niaj hnub no yog ib qho kev cuam tshuam loj tshaj plaws rau kev txhim kho ntau yam kab mob ntawm tib neeg. Immunoprophylaxis yog ua raws li National Immunization Schedule. Tab sis muaj cov tshuaj tiv thaiv uas tsis suav nrog hauv cov npe uas yuav tsum tau ua. Nov yog tshuaj tiv thaiv Synflorix.
Kev sib sau thiab tso tawm daim ntawv
Cov tshuaj tiv thaiv yog siv rau cov menyuam yaus hnub nyoog 6 lub lis piam mus txog 5 xyoos los tiv thaiv kab mob pneumococcal. Cov tshuaj no yog tsim nyob rau hauv daim ntawv ntawm cov kua dawb rau kev txhaj tshuaj. Thaum nyob, ob txheej yog tsim: precipitate thiab ib tug supersufficient pob tshab kua.
Pneumococcal polysaccharides ntawm cov serotypes sib txawv yog siv los ua cov ntsiab lus tseem ceeb hauv cov tshuaj tiv thaiv. Serotypes yog subspecies ntawm ib tus kab mob pathogenic uas txawv hauv cov qauv antigenic. Ib koob txhaj tshuaj (1/2 milliliter) muaj:
- peb micrograms txhua ntawm 19F, 4, 18C serotypes;
- ib microgram txhua 1, 5, 9V, 6V, 7F, 14, 23F serotypes;
- protein D ntawm untyped hom ntawm Haemophilus influenzae, tetanus thiab diphtheria proteins;
- txhuas phosphate - ua ib qho adsorbent.
dej sterile rau kev txhaj tshuaj yog siv raws li diluent.
tshuaj tshuaj tiv thaiv kab mob
Raws li qhov txiaj ntsig ntawm cov tshuaj pharmacological tseem ceeb ntawm qhov kev npaj kho mob no, cov tshuaj immunoglobulins tshwj xeeb raug tsim tawm hauv lub cev. Kev txhaj tshuaj "Synflorix" muaj cov tshuaj ntawm kaum feem ntauHom kab mob Streptococcus pneumoniae kab mob. Cov kab mob no yog lub luag haujlwm rau qhov tshwm sim ntawm pathologies xws li mob ntsws, mob meningitis, sepsis, otitis media. Cov tshuaj tiv thaiv ua haujlwm zoo li nws ua rau lub cev tiv thaiv kab mob, tab sis tsis ua rau muaj tus kab mob tiag tiag.
Thaum lub cev raug cov kab mob txawv teb chaws, xws li kab mob lossis kab mob, tib neeg lub cev tiv thaiv kab mob pib tsim cov tshuaj tiv thaiv kab mob, uas pab kom paub txog thiab rhuav tshem cov kab mob. Tom qab ntawd, lawv tseem nyob hauv tib neeg lub cev los tiv thaiv nws los ntawm kev sib kis los ntawm tib tus kab mob.
Yog li, kev tiv thaiv kab mob tshwm sim. Cov kws kho mob hu nws tshwj xeeb vim nws ua haujlwm tshwj xeeb tiv thaiv kab mob lossis kab mob. Kev txhaj tshuaj "Synflorix" muaj cov polysaccharides ntawm cov kab mob pneumococcal, uas feem ntau ua rau muaj cov kab mob sib kis. Cov khoom no, nrog rau cov proteins ntawm kab mob diphtheria, Haemophilus influenzae thiab tetanus, tau nce kev tiv thaiv kab mob thiab tsis tshua muaj kab mob.
Lawv muaj peev xwm ua kom cov tshuaj tiv thaiv kab mob tsis ua rau muaj kev kis tus kabmob tiag. Lub cim xeeb tiv thaiv kab mob uas tseem tshuav tom qab txhaj tshuaj tiv thaiv tso cai rau koj kom paub sai sai ntawm ib lossis lwm cov kab mob microbe thiab pib ua kom sai ntawm immunoglobulins. Yog li, cov txheej txheem pathological raug txwv nyob rau theem pib ntawm nws txoj kev loj hlob.
Kev qhia thiab kev npaj rau kev tswj hwm tshuaj tiv thaiv
Raws li cov lus qhia raudaim ntawv thov, "Synflorix" yog qhia thaum muaj hnub nyoog ntawm rau lub lis piam mus rau tsib xyoos. Nws yog siv los tiv thaiv kab mob ntsws, otitis media, meningitis, sepsis thiab lwm yam kab mob tshwm sim los ntawm Streptococcus pneumoniae. Cov menyuam noj qab haus huv uas tsis muaj qee yam kab mob ntev tsis tas yuav muaj kev npaj rau kev txhaj tshuaj. Feem ntau cov tshuaj tiv thaiv no tau muab ua ntej tus menyuam nkag mus rau qib kindergarten. Hauv lwm qhov xwm txheej, qhov muaj peev xwm txhaj tshuaj tiv thaiv yuav tsum tau tham nrog tus kws kho mob tshwj xeeb. Txhawm rau kom tus menyuam hloov cov tshuaj tiv thaiv kom yooj yim li sai tau, koj yuav tsum ua raws li cov lus pom zoo hauv qab no:
- Ob peb hnub ua ntej txhaj tshuaj tiv thaiv, koj tsis tuaj yeem mus rau qhov chaw pej xeem. Kev tiv tauj nrog lwm tus menyuam yuav tsum zam kom tsis txhob kis tus kabmob.
- Nws tsis pom zoo kom qhia cov khoom noj tshiab ntxiv rau tus menyuam, cov khoom txawv txawv, vim qee qhov lawv tuaj yeem ua rau muaj kev fab tshuaj.
- Nws yog ib qho tseem ceeb uas yuav tsum tau saib xyuas tus menyuam lub siab lub ntsws. Cov niam txiv yuav tsum qhia nws txog kev txhaj tshuaj tiv thaiv, ua li cas thiab vim li cas thiaj li ua tiav.
- Yog tias muaj ib tug neeg hauv tsev neeg mob khaub thuas lossis lwm yam kab mob sib kis, yuav tsum tau txhaj tshuaj tiv thaiv kom txog thaum nws rov zoo tag.
- Thaum cov niam txiv tsis paub meej txog kev noj qab haus huv ntawm lawv tus menyuam, lawv yuav tsum sab laj nrog kws kho mob txhawm rau txiav txim siab qhov muaj peev xwm txhaj tshuaj tiv thaiv.
Txoj kev thov thiab ntau npaum li cas
Tshuaj tiv thaiv "Synflorix"nqa tawm nyob rau hauv lub cheeb tsam ntawm lub deltoid nqaij los yog pem hauv ntej ntawm tus ncej puab los ntawm txoj kev intramuscular. Txoj kev txhaj tshuaj yuav txawv nyob ntawm seb muaj hnub nyoog li cas ntawm cov menyuam yaus. Lub sijhawm txhaj tshuaj tiv thaiv raws hnub nyoog:
- 6 lub lis piam - 6 lub hlis: Plaub koob tshuaj tiv thaiv tau pom zoo kom muaj kev tiv thaiv siab. Thawj qhov kev txhaj tshuaj yog nqa tawm ntawm 6 lub hlis, ob zaug ntxiv - nrog rau lub sijhawm ntawm 30 hnub. Revaccination (thov thib plaub) yog muab 6 lub hlis tom qab txhaj tshuaj zaum kawg.
- Cov menyuam mos ntxov ntxov: lawv txoj kev txhaj tshuaj tiv thaiv zoo ib yam li yav dhau los. Qhov txawv ntawm qhov no tsuas yog txhaj tshuaj thawj zaug thaum muaj hnub nyoog 2 hlis.
- 7-11 lub hlis: 2 koob tshuaj 1 lub hlis sib nrug. Rov qhia dua yog ua rau xyoo ob ntawm lub neej.
- 1-5 xyoos: Cov txheej txheem txhaj tshuaj kom raug muaj ob koob tshuaj 2 lub hlis sib nrug.
Kev txhaj tshuaj yog ib qho kev tawm tsam uas muaj qee yam txaus ntshai. Yuav kom txo tau lawv, koj yuav tsum ua raws li cov lus qhia rau kev siv. Cov tshuaj tiv thaiv "Synflorix" tsuas yog ua los ntawm kev txhaj tshuaj intramuscular. Ua ntej pib txoj kev kho mob, tus kws kho mob tshwj xeeb yuav tsum ntsuas tus me nyuam qhov kub thiab txias. Hauv cov menyuam yaus hnub nyoog qis dua ib xyoos, kev txhaj tshuaj yog nqa tawm hauv qhov chaw sab hauv ntawm tus ncej puab, thaum muaj hnub nyoog laus - hauv thaj tsam ntawm cov leeg deltoid. Tus kws kho mob yuav tsum tshuaj xyuas qhov xwm txheej ntawm cov tshuaj tiv thaiv, muaj kev puas tsuaj rau cov khoom siv, daim ntawv lo, hnub tas sij hawm. Qhov chaw txhaj tshuaj yog kho nrog tshuaj tua kab mob. Tsis yog nyob rau hauvTsis muaj ib qho xwm txheej twg yuav tsum tau tso cai rau cov tshuaj no tuaj rau hauv kev sib cuag nrog cov tshuaj tua kab mob, vim qhov no tuaj yeem ua rau cov tshuaj tiv thaiv Synflorix inactivation. Cov tshuaj yog siv tom qab cov tshuaj mus txog chav tsev kub. Qhov koob tshuaj txhaj yog ½ milliliter.
Thaum siv qhov kev kho mob no, cov niam txiv yuav tsum nug tus kws kho mob txog qhov muaj peev xwm ntawm qee qhov kev tshwm sim tom qab txhaj tshuaj tiv thaiv thiab qhov tshwm sim ntawm cov tshuaj.
Contraindications rau kev tswj hwm tshuaj tiv thaiv
Muaj qee cov menyuam yaus uas txhaj tshuaj tiv thaiv lossis muab ceev faj. Pawg no suav nrog:
- muaj cov txheej txheem pathological nyob rau theem nquag, uas yog nrog rau qhov kub siab (ntau dua 39 ° C);
- cov menyuam yaus uas paub qhov ua xua lossis tsis hnov tsw rau cov khoom ntawm cov tshuaj tiv thaiv no.
Nrog qee qhov ceev faj, cov tshuaj siv rau cov menyuam yaus uas muaj coagulopathy. Cov mob no yog los ntshav. Yog tias cov tshuaj tiv thaiv tau txhaj tshuaj intramuscularly, muaj qhov tshwm sim ntau ntawm kev puas tsuaj rau cov hlab ntsha thiab los ntshav. Hauv cov menyuam yaus uas muaj keeb kwm qaug dab peg, txhaj tshuaj tiv thaiv tom qab sab laj nrog kws kho mob thiab sau tshuaj kom tsim nyog los tiv thaiv qaug dab peg.
Puas muaj teeb meem los ntawm cov tshuaj tiv thaiv Synflorix ua tau?
Cov kev mob tshwm sim, teeb meem, muaj peev xwm tshwm sim rau cov tshuaj tiv thaiv
Qhov tshwm sim ntawm qee qhovCov kev mob tshwm sim los ntawm kev qhia txog cov tshuaj tiv thaiv yog vim tus neeg rhiab heev thiab cov yam ntxwv ntawm tus menyuam lub cev, nrog rau cov txheej txheem txhaj tshuaj. Nws yog ib qho tseem ceeb heev kom nkag siab tias cov tshuaj tiv thaiv no tsis muaj cov kab mob uas muaj sia nyob, tab sis tsuas yog tawg ntawm lawv cov phab ntsa ntawm tes. Yog li ntawd, cov tshuaj no tsis tuaj yeem ua rau muaj kab mob tiag tiag. Cov tshuaj tiv thaiv tom qab tau muab faib raws li qhov zaus ntawm lawv txoj kev loj hlob mus rau:
- Common (tej zaum yuav cuam tshuam txog li 1 ntawm 100 tus menyuam yaus) - Kev nkag mus ntawm qhov chaw txhaj tshuaj.
- Ntau heev (muaj feem cuam tshuam ntau dua 1 ntawm 10 tus menyuam yaus) - mob, o, tawm dej ntawm qhov chaw txhaj tshuaj, kub taub hau qis, tsis qab los noj mov, chim siab, tsaug zog.
- Tsis tshua muaj (tsawg dua 1 ntawm 100 tus menyuam yaus): los ntshav, tawm pob, ua pob khaus, ntuav, raws plab, quaj txawv txav.
- Rare (muaj feem cuam tshuam rau 1 ntawm 10,000 tus menyuam): anaphylaxis, qaug dab peg, ua xua dermatitis.
Cov teeb meem ntawm cov tshuaj tiv thaiv no suav nrog cov xwm txheej hauv qab no:
- kev puas tsuaj rau cov hlab ntsha lossis paj hlwb;
- tsim ntawm ib qho abscess, lymphadenitis, phlegmon.
Kev kho mob tom qab txhaj tshuaj tiv thaiv los ntawm "Synflorix" tshuaj tiv thaiv
Syrups uas muaj paracetamol lossis ibuprofen yog siv los kho tus mob febrile tom qab txhaj tshuaj.
o me ntsis, hyperemia thiab mob hauv qhov chaw txhaj tshuaj yog cov tsos mob ntawm lub cev uas tsis tas yuav muaj kev kho mob. Lawv tsim los ntawm cov txheej txheem inflammatory hauv cov leeg nqaij. Cov txhuas phosphate muaj nyob rau hauv cov tshuaj tiv thaiv no ua rau hauvraws li sorbent. Nws tsis tso cai rau polysaccharides nqus mus rau hauv cov hlab ntsha, ua rau me me hauv zos o. Qhov kev raug zoo li no ua rau lub cev tsis muaj zog tiv thaiv kab mob.
Qhov no tau lees paub los ntawm cov lus qhia rau Synflorix.
Kev kho mob ntawm cov kev mob tshwm sim muaj feem cuam tshuam nrog kev kho mob. Thaum tus me nyuam ua npaws, siv cov tshuaj antipyretics. Rau tib lub hom phiaj, nws raug tso cai siv tshuaj antipyretic. Tshwj xeeb tshaj yog rau cov me nyuam, cov tshuaj no muaj nyob rau hauv daim ntawv ntawm syrups. Nrog rau txoj kev loj hlob ntawm kev tsis haum tshuaj, desensitizing thiab tshuaj antihistamine tshuaj pharmacological raug muab.
Cov tswv yim thiab cov lus pom zoo
Kuv puas yuav tsum tau txhaj tshuaj "Synflorix" ua ntej pib kawm qib kindergarten? Cia peb kawm saib.
Nws tau ntseeg ntau ntawm cov niam txiv tias kev txhaj tshuaj tiv thaiv tus menyuam tsuas yog nyob ntawm lawv lub siab nyiam xwb. Cov kws kho mob nug cov neeg zoo li no ib lo lus nug - lawv yuav tiv thaiv tus menyuam li cas los ntawm kev kis kab mob txaus ntshai thiab lawv qhov tshwm sim. Cov lus teb yog, feem ntau, tsis yog. Qhov txiaj ntsig zoo ntawm kev txhaj tshuaj tiv thaiv tau raug sim ntau tiam neeg. Cov kws kho mob pom zoo kom txhaj tshuaj tiv thaiv:
- Ntau tshaj 100 xyoo, cov tshuaj tiv thaiv tau tiv thaiv tib neeg los ntawm cov kab mob txaus ntshai.
- Kev txhaj tshuaj tiv thaiv thaum yau tso cai rau koj hloov pauv sai sai rau qhov chaw sab nraud. Tib lub sijhawm, cov tshuaj tiv thaiv kab mob rau cov kab mob txaus ntshai tau tsim tawm hauv ib tus neeg thiab qhov kev pheej hmoo ntawm kev mob nrog lawv tau txo qis.
- Kev txhaj tshuaj tiv thaiv tseem ceeb tiv thaiv kab mob, hauv kev tawm tsamyam tshuaj twg tsis muaj zog. Lawv yog kab mob diphtheria thiab polio.
- Vim qhov xwm txheej ib puag ncig tsis zoo, kev tiv thaiv menyuam yaus raug txo qis.
- Cov tshuaj tiv thaiv tsuas yog siv cov kab mob xwb, tshwj xeeb tshaj yog polysaccharides, uas tsis muaj kab mob thiab tsis ua rau muaj kab mob tiag.
Muab cov lus tseeb no, qhov txiaj ntsig ntawm kev txhaj tshuaj tiv thaiv tsis muaj kev ntseeg siab.
Kev Sib Tham Tshuaj
txhais tau tias "Synflorix" yog siv ua ke nrog lwm cov tshuaj tiv thaiv, yog tias lawv tau muab tshuaj rau ntau qhov chaw ntawm lub cev. Kev siv cov tshuaj tiv thaiv keeb kwm yav dhau los ntawm kev kho mob nrog cov tshuaj tiv thaiv kab mob, cytostatics, tshuaj tua kab mob tau tso cai. Hauv qhov no, muaj peev xwm tsis tau txais kev tiv thaiv kab mob, vim tias lub cev tiv thaiv kab mob tsis muaj zog heev vim muaj kev cuam tshuam ntawm cov tshuaj saum toj no.
Kev siv cov tshuaj immunoglobulins kuj txo cov tshuaj tiv thaiv kab mob rau kev txhaj tshuaj. Tib lub sijhawm, lub pas dej uas tsim nyog ntawm cov tshuaj tiv thaiv tshwj xeeb tsis raug tsim tawm.
Analogues
Muaj lwm yam tshuaj tiv thaiv kab mob los ntawm cov kab mob pneumococcal. Cov no suav nrog:
- "Prevenar", uas muab kev tiv thaiv los ntawm 7 hom kab mob no;
- Prevenar 13 nrog 6 ntau hom ntxiv;
- Pnevmovax II yog ib qho tshuaj tiv thaiv ntau yam uas muaj 23 hom kab mob pneumococcal polysaccharides.
Txhua yam tshuaj tiv thaiv saum toj no tau tso cai los ntawm WHO thiab tau siv los ua tiav.
Tshuaj xyuas txog cov tshuaj tiv thaiv "Synflorix"
Niam txivcov menyuam yaus uas tau txhaj tshuaj tiv thaiv kab mob no tau tawm tswv yim zoo txog nws. Feem ntau, cov tshuaj tiv thaiv no tau txais txiaj ntsig zoo los ntawm cov menyuam mos.
Raws li kev tshuaj xyuas ntawm Synflorix, cov menyuam yaus feem ntau ntsib qhov kub thiab txias me ntsis, uas, raws li cov neeg ua haujlwm kho mob, qhia txog kev tsim kev tiv thaiv kab mob los ntawm pneumococci. Tsis muaj kev tsis haum tshuaj hnyav lossis lwm yam kab mob pathological tau sau tseg los ntawm niam txiv.
Peb tau tshuaj xyuas cov lus qhia rau kev txhaj tshuaj "Synflorix".
