Kev kuaj mob kom raug qee zaum nyob ntawm qhov kev kuaj mob nkaus xwb. Tsis tas li ntawd, kev tshawb fawb ntau yam yog qhov tsim nyog, vim tias kev tsim kom raug ua rau muaj qee yam kev tsis sib haum xeeb yog tus yuam sij rau kev kho kom zoo. Yog li ntawd, cov kws kho mob feem ntau xa lawv cov neeg mob mus rau kev kuaj sim, vim tsuas yog lawv tuaj yeem pom cov duab qhia txog kev noj qab haus huv ntawm tib neeg. Ntxiv nrog rau qhov paub zoo txog kev tso zis thiab kuaj ntshav, muaj ntau qhov kev tshawb fawb suav tsis txheeb. Ntawm lawv, piv txwv li, kev tsom xam ntawm FSH.
Study Purpose
Follicle-stimulating hormone, los yog FSH, yog ib feem ntawm ib pawg ntawm cov tshuaj uas ua kom lub cev ua haujlwm ntawm gonads thiab ua kom muaj kev loj hlob ntawm cov txiv neej thiab poj niam. Nrog rau cov tshuaj luteinizing hormone, los yog LH, thiab prolactin, FSH pab tsim cov yam ntxwv ntawm kev sib deev, thiab tseem ua rau muaj kev hloov pauv tsis tu ncua.cev xeeb tub, ovulation thiab phev maturation. Tag nrho cov no thaum kawg ua ke tso cai rau lub qe kom fertilized. Dab tsi yog FSH cov tshuaj hormones hauv cov ntshav ntawm cov poj niam thiab nws cov qauv muaj kev txaus siab rau ntau tus.
Cov tshuaj hormones tsim nyob qhov twg?
Cov tshuaj hormones LH thiab FSH yog tsim los ntawm anterior lobe ntawm adenohypophysis thiab koom nrog pawg gonadotropic. Yog tias qib ntawm cov tshuaj hormones hauv cov ntshav siab tshaj qhov kev cai, lub cev nres lawv cov synthesis, thiab, nrog rau qhov tsis txaus, lawv cov khoom tsim tau nce.
FGS kev tshuaj xyuas yog ua ib feem ntawm kev kuaj mob ntawm cov xwm txheej hauv qab no:
- Kev muaj menyuam tsis muaj menyuam hauv cov tib neeg ntawm ob leeg pojniam.
- Tsis ua haujlwm ntawm lub qog pituitary.
- Kev mob khaub thuas tsis sib xws.
- Kev cuam tshuam hauv kev ua haujlwm ntawm zes qe menyuam lossis qe menyuam.
- Sperm underdevelopment.
- ncua sijhawm lossis ntxov ntxov ntawm cov menyuam yaus.
Dab tsi txhais qhov kev tshuaj ntsuam?
Ntawm lwm yam, kev tshuaj xyuas ntawm FSH (nws yog dab tsi hauv cov poj niam, peb tau piav qhia) ua rau nws muaj peev xwm txiav txim siab qhov cia ntawm ovulation hauv cov neeg mob uas muaj zes qe menyuam tsis ua haujlwm. Nyob ntawm lub hnub nyoog thiab tus mob ntawm cov neeg mob, nws theem yuav hloov mus thoob lub neej. Cev xeeb tub, poj niam cev xeeb tub, lossis muaj kev coj khaub ncaws tuaj yeem cuam tshuam rau qib ntawm cov tshuaj no.
Kev qhia
Feem ntau, cov poj niam yuav tsum tau kuaj xyuas lawv cov qib FSH. Txawm li cas los xij, yog tias muaj menyuam tsis taus, pituitary pathologies lossis gonadal insufficiency raug xav tias, qhov kev tshawb fawb no tuaj yeem raug sau rau cov neeg mob ntawm ob leeg. menyuamQhov kev tshuaj xyuas no raug sau tseg yog tias kev puberty tshwm sim lig dhau los lossis, ntawm qhov tsis sib xws, ntxov dhau.
Cov cim qhia ntawm kev loj hlob ntxov ntxov ntawm kev tsim tawm ntawm cov menyuam yaus yog:
1. Lub mis augmentation thiab qhov pib ntawm kev coj khaub ncaws nyob rau hauv cov ntxhais.
2. Kev loj hlob ntawm qhov chaw mos ntawm cov tub.
3. Cov nroj tsuag txawv txav hauv qhov chaw mos.
Cov cim qhia no yog qhov ua rau muaj kev txhawj xeeb, vim tias lawv tuaj yeem qhia txog cov kab mob hauv lub cev ntawm qhov xwm txheej hnyav dua, piv txwv li, mob hauv hypothalamus, qog pituitary, gonads, thiab lwm yam.
Kev xeem FSH rau txiv neej yog dab tsi?
Nyob hauv lub cev ntawm ib tug txiv neej, FSH muab cov dej num uas ua rau muaj kev vam meej fertilization. Cov tshuaj hormones yog lub luag haujlwm rau kev tsim cov phev, nrog rau kev loj hlob ntawm cov tubules seminiferous thiab testicles. Cov lus qhia tseem ceeb rau kev sim cov txiv neej yog:
- Txuag libido.
- Kev ua txhaum cai.
- Kev tsis muaj menyuam.
- Late puberty in teenscence.
Kev tsis muaj menyuam
Qhov laj thawj tseem ceeb ntawm kev xeem FSH rau cov poj niam yog infertility, qhov laj thawj uas yuav pab txheeb xyuas qhov kev soj ntsuam. Kev tsis txaus lossis ntau dhau ntawm cov tshuaj hormones hauv cov poj niam cov ntshav tuaj yeem yog vim li cas rau qhov tsis muaj peev xwm xeeb tub thiab yug menyuam. Nyob rau hauv rooj plaub no, yuav tsum kho kho, uas yuav normalize cov tshuaj hormones thiab cia tus poj niam xeeb tub thiab yug me nyuam.
Kev ua poj niam los ntshav ntawm qhov ntim tsis txaus thiab kuj tsis tshua muaj, thiablawv qhov tsis tuaj kawm tiav kuj yog ib qho laj thawj rau kev dhau qhov kev tshuaj ntsuam no. Nws yog ib qho tsim nyog txawm tias thaum cev xeeb tub. Qhov no kuj suav nrog los ntshav ntawm lub voj voog.
Rau cov ntxhais hluas, kev tshuaj xyuas yog muab rau hauv cov xwm txheej uas lawv muaj lub cev thiab kev sib deev ntxov ntxov, lossis rov ua dua, qeeb hauv nws. Txoj kev tshawb no yuav pab txiav txim seb qhov ua rau muaj qhov tsis zoo li no thiab sau ntawv kho kom txaus.
Npaj rau kev tshuaj ntsuam
Npaj rau kev pub ntshav rau qib ntawm follicle-stimulating hormone FSH tsis txawv ntawm lwm yam kev tshuaj xyuas. Ua ntej noj ntshav, koj yuav tsum tsis suav nrog kev ntxhov siab thiab kev ua si lub cev hnyav, tsis txhob haus luam yeeb thiab haus cawv. Ntshav tau noj nruj me ntsis ntawm lub plab khoob, yog li nws yog qhov zoo dua los ncua kev noj tshais ib ntus tom qab cov txheej txheem. Ua ntej yuav ntshav, koj yuav tsum ceeb toom rau tus kws kuaj mob txog cov tshuaj uas koj noj.
Cov txheej txheem rau kev noj cov khoom rau kev tshuaj xyuas yog yooj yim. Nws suav nrog kev noj ntshav hauv peb lub raj tshuaj hauv ib nrab teev. Qib ntawm FSH hauv cov poj niam zoo li hloov pauv nyob ntawm lub sij hawm txij thaum pib ntawm kev coj khaub ncaws, yog li qhov kev ntsuam xyuas tau muab rau qee hnub. Nyob rau hauv tus qauv version, ntshav pub rau ib lub lim tiam tom qab pib lub voj voog tshiab thaum lub sij hawm follicular. Cov kev txwv no tsis siv rau cov txiv neej, txij li kev sib xyaw ntawm cov tshuaj hormones tshwm sim tsis tu ncua hauv lawv lub cev.
Tom qab kuaj ntshav, kev tshawb fawb ntawm cov khoom tau raug ua tiav. Yog li, nws tuaj yeem ntsuas qhov ntsuas ntawm cov tshuaj hormones hauv tus neeg mob lub cev.
Yog tias qib FSH tshaj li tus nqi ib txwm muaj, peb tab tom tham txog tus kab mob tseem ceeb ntawm gonads. Qib qis qhia tau hais tias muaj kab mob thib ob, qhov ua rau, feem ntau yuav, yog qhov ua haujlwm tsis zoo ntawm lub cev hypothalamus lossis pituitary caj pas.
Yog xav tias muaj menyuam tsis taus, ntxiv rau qhov kev soj ntsuam FSH, ntshav kuj tau pub rau LH. Xws li kev tshuaj ntsuam xyuas pab txiav txim seb yog vim li cas vim li cas nws thiaj li xeeb tsis tau menyuam, ntsuas kev ua haujlwm ntawm lub caj pas pituitary thiab kev ua haujlwm ntawm tus neeg mob, lossis txheeb xyuas qhov yuav tsum tau ua ua ntej rau kev tsis txaus siab rau cov menyuam yaus lossis cov hluas.
Norma
Nws twb tau hais los saum toj no tias theem ntawm FSH hauv cov poj niam tsis ruaj khov thiab txawv nyob ntawm theem pib ntawm lub voj voog:
- Nyob rau lub sijhawm follicular - 1, 3-9, 9 zib ntab / ml.
- Nyob rau lub sijhawm ovulatory - 6, 16-17, 2 mIU / ml.
- Nyob rau lub sijhawm luteal - 1, 1 - 9, 2 zib ntab / ml.
rau txiv neej
Txiv neej ib txwm FSH qib nyob ntawm hnub nyoog:
- Cov menyuam yaus hnub nyoog qis dua ib xyoos - 3.5 zib ntab / ml.
- Txog tsib xyoos - 1.45 IU / ml lossis ntau dua.
- Txog kaum xyoo - 3.03 IU/ml thiab ntau dua.
- Teenagers ntawm 11 txog 14 xyoo - 0.35-6.3 IU/ml.
- Txog 20 xyoo - 0.5 - 9.98 IU/ml.
- Hauv cov neeg laus, tus nqi ntawm 0.95-12 mU / ml yog suav tias yog tus qauv. Peb xav txog qhov kev txiav txim siab ntawm kev tshuaj xyuas rau FSH thiab cov nqi ib txwm muaj.
Kev tsis sib haum los ntawm tus qauv
Cov txiaj ntsig ntawm kev kuaj ntshav rau qib FSH tso cai rau koj txheeb xyuas tus kab mob thawj lossis theem nrab. ThiabYog hais tias nyob rau hauv thawj kis ntawm zes qe menyuam insufficiency yog txuam nrog rau lawv underdevelopment, ces nyob rau hauv lub thib ob rooj plaub muaj ib tug ua txhaum ntawm lub pituitary caj pas los yog hypothalamus.
Hauv thawj qhov tsis txaus, LH thiab FSH qib siab dua li qub thiab qhia cov hauv qab no:
- Kev puas tsuaj hauv kev loj hlob ntawm zes qe menyuam, suav nrog kev ua tsis tiav hauv kev sib txuas ntawm cov tshuaj hormones steroid, chromosomal abnormalities xws li Shereshevsky-Turner thiab Kallman syndromes.
- Lub zes qe menyuam ua tsis taus vim hluav taws xob, tshuaj khomob thiab kab mob autoimmune.
- Anovulation. Sawv cev rau qhov tsis tiav ntawm ovulation. Qhov ua rau tej zaum yuav yog endocrine pathologies, oncological tsim nyob rau hauv lub zes qe menyuam, kab mob polycystic thiab kab mob adrenal.
nce qib cov tshuaj hormones hauv cov txiv neej qhia thawj qhov tsis ua haujlwm ntawm lub qe menyuam, uas tuaj yeem tshwm sim los ntawm:
- Kev cuam tshuam tsis zoo xws li kab mob, kab mob, tshuaj kho mob, kev raug mob, kab mob autoimmune, mumps, hluav taws xob, thiab lwm yam.
- Cov kab mob xws li chromosomal abnormalities xws li Klinefelter's syndrome. Kev sim rau FSH thiab LH tam sim no tau ua tiav zuj zus lawm.
Nyob rau me nyuam
Nrog kev nce qib FSH hauv tus menyuam, peb tuaj yeem tham txog kev puberty thaum ntxov. Qhov siab tsis zoo ntawm LH thiab FSH tuaj yeem qhia txog kev loj hlob ntawm cov yam ntxwv ntawm kev sib deev tom qab. Hauv cov tub hluas, qhov pathology no tsawg dua li cov ntxhais.
Precocious puberty yuav qhia tau tias muaj cov kab mob hauv qab no:
- Testicular qog.
- Cysts los yogneoplasms hauv zes qe menyuam.
- Hommon-secreting qog.
- Kev cuam tshuam hauv kev ua haujlwm ntawm lub hauv nruab nrab paj hlwb.
Kev puberty qeeb qeeb kuj yog vim li cas thiaj tau sau tshuaj ntsuam xyuas rau FSH ua ib feem ntawm kev kuaj xyuas. Cov kab mob hauv qab no tuaj yeem dhau los ua qhov ua rau ncua sijhawm puberty:
- kab mob oncological.
- Kev ua tsis tiav ntawm zes qe menyuam lossis qe qe.
- kab mob sib kis.
- Klinefetel syndrome hauv cov tub thiab Shereshevsky-Turner syndrome hauv cov ntxhais, uas yog tshwm sim ntawm chromosomal abnormalities.
- Lub cev qis qis qis mus txog qhov tsis txaus ntseeg.
- Hommon deficiency.
Kev noj ntawm qee cov tshuaj tuaj yeem cuam tshuam rau qib FSH ntawm kev nce lossis txo qis. Qib ntawm cov tshuaj hormones nce tom qab noj tshuaj raws li cimetidine, clomiphene, levodopa thiab digitalis. Kev txo qis hauv qib tuaj yeem ua rau cov tshuaj tiv thaiv qhov ncauj thiab phenothiazine. Kev nce qib tshuaj hormones kuj yog yam ntxwv ntawm cov neeg haus luam yeeb.
Yog li, kev kuaj ntshav rau FSH tso cai rau koj los txiav txim siab muaj ntau yam pathologies hauv kev ua me nyuam ntawm cov poj niam thiab txiv neej. Kev ncua kev xa khoom ntawm kev tshuaj ntsuam yog tias koj xav tias muaj kab mob uas twb muaj lawm yeej tsis tsim nyog.