Cov tshuaj "Itraconazole" (cov ntsiav tshuaj, tshuaj pleev, qab zib, tshuaj lossis tshuaj ntsiav) yog siv los kho ntau yam kab mob fungal. Txawm li cas los xij, nws muaj txiaj ntsig zoo rau kev kho mob ntawm cov kab mob hauv cheeb tsam sib txawv ntawm lub cev.
tshuaj kho mob
Cov tshuaj nws tus kheej thiab ib qho analogue ntawm "Itracanozol" belongs rau chav kawm ntawm cov tshuaj tua kab mob triazoles. Cov tshuaj tiv thaiv hluavtaws no tiv thaiv cov synthesis ntawm ergosterol, uas yog qhov tsim nyog rau kev ua haujlwm ntawm cov fungi. Cov tshuaj "Itraconazole" inhibits kev loj hlob ntawm dermatophytes, Candida poov xab fungi, pwm fungi thiab lwm yam kab mob. Qee hom kab mob kab mob no tiv taus qhov kev ua ntawm tus neeg sawv cev no.
Cov tshuaj "Itraconazole" muaj nyob rau hauv cov ntsiav tshuaj, tshuaj ntsiav, hauv daim ntawv ntawm cov tshuaj (kua), tshuaj pleev. Muaj ntau tshaj li ib qho analogue ntawm Itraconazole ntawm kev muag khoom. Cov tshuaj zoo sib xws muaj nyob rau hauv ntau hom tshuaj.
Ib qho analogue ntawm "Itraconazole" thiab, qhov tseeb, cov tshuaj no nws tus kheej feem ntau siv rauKev kho mob ntawm cov kab mob fungal ntawm cov hlab ntsws, tshwj xeeb hauv lub ntsws. Cov tshuaj no kuj tseem siv los kho cov neeg mob uas muaj kab mob fungal hauv caj pas, qhov ncauj lossis txoj hlab pas. Feem ntau, tus kab mob no cuam tshuam rau cov rau tes ntawm tus neeg. Hauv qhov no, lwm hom tshuaj "Itraconazole" yog siv - tshuaj pleev rau kev siv sab nraud, uas muaj txiaj ntsig zoo tiv thaiv kab mob ntawm cov rau tes lossis tawv nqaij. Nws kuj tau sau rau psoriasis.
Cov lus qhia rau kev siv
Cov tshuaj no thiab nws cov analogues yog siv rau cov kab mob hauv qab no:
• ringworm;
• candidiasis;
• sporotrichosis;
• versicolor;
• onychomycosis;
• blastomycosis;
• cryptococcosis;
• Keratomycosis;
• paracoccidioidomycosis;
• systemic aspergillosis thiab candidiasis;
• histoplasmosis;
• tropical mycosis.
Lub sijhawm kho yuav raug kho raws li daim duab kho mob. Feem ntau, cov tshuaj no tau noj ib zaug ib hnub. Cov kev kho mob feem ntau siv:
• Pityriasis versicolor: 200mg ib lub lis piam;
• ringworm: 200 mg txhua lub lim tiam lossis 100 mg rau 15 hnub;
• Onychomycosis: 3 lub hlis 200mg lossis lub lis piam 200mg ob zaug ib hnub;
• Dermatophytosis ntawm tes thiab ko taw: 200mg ib lub lim tiam lossis 100mg rau 1 lub hlis;
• candidiasis: 100 mg rau 15 hnub;
• Keratomycosis: 200mg rau 3 lub lis piam.
Txoj kev noj thaum twgmob ntsws
Rau kev kho cov kab mob fungal ntawm cov kab mob ua pa, Itraconazole ntsiav tshuaj lossis tshuaj ntsiav tau sau tseg. Analogues yog pheej yig dua, tab sis lawv yuav muaj kev cuam tshuam ntau dua nyob rau lub sijhawm, yog li tus kab mob no nyuaj rau kev swb hauv lub sijhawm luv tshaj plaws. Cov ntsiav tshuaj lossis tshuaj ntsiav tau noj 1-2 zaug hauv ib hnub, thaum lub sijhawm lossis tom qab noj mov. Feem ntau nws yuav siv sij hawm tsawg kawg 3 lub hlis los kho tus kab mob fungal. Qee zaum, tus kws kho mob tuaj yeem sau cov kev kho mob hauv qab no: 3 ntsiav tshuaj ib hnub rau 3 hnub, thiab tom qab ntawd 3 lub hlis, 1-2 ntsiav tshuaj ib hnub.
Npaj tshuaj tiv thaiv tus ntiv tes
Cov tshuaj "Itraconazole" - cov ntsiav tshuaj uas kuj tau sau tseg rau kev kho mob ntawm tus ntsia thawv kab mob fungal. Rau kev kho kom tiav, nws tau noj 1 zaug hauv ib hnub rau 12 lub lis piam. Cov txiaj ntsig zoo dua yog cov tshuaj hauv qhov ncauj "Itraconazole". Nws tau noj 1-4 lub lis piam 1-2 zaug hauv ib hnub. Nyob rau tib lub sijhawm, kom nqus tau sai, cov tshuaj tau noj ntawm lub plab khoob. Tsuas yog tus kws kho mob tuaj koom tuaj yeem xaiv qhov kev pom zoo tshaj plaws rau kev noj tshuaj lossis sau tshuaj analogue ntawm Itraconazole, leej twg yuav coj mus rau hauv tus account qhov hnyav ntawm tus kab mob thiab cov xwm txheej ntawm tus neeg mob. Hauv cov xwm txheej tshwj xeeb, rau kev kho cov kab mob fungal ntawm cov rau tes, lwm hom tshuaj "Itraconazole" yog siv - cov tshuaj pleev uas siv rau thaj chaw cuam tshuam 1-2 zaug hauv ib hnub.
Lwm siv tshuaj
Txhua yam analogue ntawm "Itraconazole" thiab cov tshuaj no nws tus kheej tau nce siv hauv kev kho mob nyuaj hauv xyoo tas losNtau hom kab mob fungal hauv cov neeg mob cuam tshuam los ntawm HIV thiab AIDS. Hauv qhov no, kev siv tshuaj rau tus kheej tsis tuaj yeem lees txais, vim tsuas yog tus kws kho mob tuaj koom tuaj yeem ntsuas tus neeg mob lub xeev kev noj qab haus huv thiab kev pheej hmoo ntawm kev noj Itraconazole.
Cov lus qhia tshwj xeeb
Cov tshuaj "Itraconazole", analogues ntawm cov tshuaj no yuav tsum tau noj raws li cov lus qhia thiab cov lus pom zoo ntawm tus kws kho mob. Hauv cov koob tshuaj me me lossis loj dua, lawv yuav ua tsis tau zoo lossis ua rau tus neeg mob noj qab haus huv.
Capsules "Itraconazole", analogues pheej yig lossis kim yog noj raws li hauv qab no: tshuaj ntsiav thiab ntsiav tshuaj tau nqos tag nrho. Txawm li cas los xij, lawv yuav tsum tsis txhob chew los yog crushed. Yog tias muaj qhov txo qis ntawm acidity hauv plab, tshwm sim, piv txwv li, los ntawm cystic fibrosis, qhov no yuav tsum tau qhia rau tus kws kho mob.
Ib txhia zaus, txoj kev siv tshuaj no yuav raug hloov. Feem ntau qhov no tshwm sim thaum tus neeg mob siv cov tshuaj hauv qab no thaum kho: Famotidine, Nizatidine, Esomeprazole, Cimetidine, Omeprazole, Ranitidine, Lansoprazole, Pantoprazole, "Rabeprazole."
YContraindications
Qee zaum, Itraconazole yog contraindicated rau cov neeg mob. Cov lus qhia rau cov tshuaj zoo sib xws feem ntau txwv tsis pub siv cov tshuaj tiv thaiv kab mob no thaum muaj kev fab tshuaj rau lawv cov khoom. Yog li ntawd, thaum sau tshuaj kho mob siv cov tshuaj no, tus kws kho mob tuaj koom yuav tsum paub tseeb tias tus neeg mob puas muaj kev fab tshuaj rau cov tshuaj uas suav nrog.rau hauv lawv.
Cov tshuaj yuav tsum tsis txhob noj los ntawm cov poj niam cev xeeb tub thiab lactating. Txhawm rau tiv thaiv kev xeeb tub thaum lub sijhawm kho, nws yog qhov yuav tsum tau siv cov tshuaj tiv thaiv zoo. Nrog ceev faj, cov tshuaj no tau muab rau cov neeg mob laus. Kev noj nws thaum yau tsuas yog ua tau yog tias qhov txiaj ntsig tshaj qhov kev pheej hmoo. Cov tshuaj tsis pom zoo rau cov neeg mob plawv tsis ua haujlwm, ischemia, mob ntsws hnyav, lub raum tsis ua haujlwm.
"Itraconazole", analogues ntawm cov tshuaj yuav tsum tsis txhob noj nyob rau hauv ib tug ob koob tshuaj nrog ib tug muaj peev xwm hla ntawm cov tshuaj. Nws yog qhov zoo tshaj plaws kom tsis nco qab txog cov tshuaj uas tsis tau noj thiab txuas ntxiv ua raws li txoj cai. Kev noj tshuaj ntau dhau ntawm cov tshuaj no lossis nws cov tshuaj analogues yuav tsum tsis txhob tso cai, vim qhov no tuaj yeem ua rau muaj mob hnyav heev.
Kev sib tham nrog lwm yam tshuaj
Ua ntej noj Itraconazole, tus kws kho mob yuav tsum paub txog yam tshuaj twg tus neeg mob tau noj ua ntej. Qhov no yog qhov tseeb tshwj xeeb tshaj yog rau kev siv tshuaj xws li Efavirenz, Everolimus, Sildenafil, Aliskiren, Rifabutin, Apixaban, Nevirapin, Dasatinib, Ibrutinib, Salmeterol, Darifenacin, Nilotinib, Carbazepine, Sunitinib, Colchicine, Rivaroxaban, Phenobarbiteny, Phenobarbital,, Vardenafil, Rifampicin, Nevirapine, Temsirolimus.
Ntxiv rau cov tshuaj saum toj no, ua ntej siv Itraconazole, koj yuav tsum qhia koj tus kws kho mob txog kev noj cov tshuaj hauv qab nonyiaj:
• anticoagulants;
• tshuaj tua kab mob;
• HIV protease inhibitors;
• cov vitamins;
• noj tshuaj pab (BAA).
Thaum siv Itraconazole thiab antacids tib lub sijhawm, tom kawg yog siv 1 teev ua ntej lossis ob peb teev tom qab noj tshuaj tiv thaiv kab mob.
Side effects
Cov tshuaj "Itraconazole" qee zaum ua rau kiv taub hau thiab qhov muag tsis pom kev hauv daim duab ob. Tsis txhob tsav tsheb lossis ua haujlwm tshuab thaum noj cov tshuaj no. Feem ntau tshaj tawm cov kev mob tshwm sim thaum noj nws muaj xws li tsam plab, nce roj tsim, raws plab, cem quav, kub hnyiab, tshwm sim ntawm qhov tsis kaj siab tom qab lub qhov ncauj; nce tawm hws, kiv taub hau, mob taub hau, los ntshav thiab mob cov pos hniav, mob nqaij, txo cov leeg nqaij, ua npaws, ua npaws, mob pob qij txha, kev nyuaj siab, txo qis kev sib deev, plaub hau poob.
Cov kev mob tshwm sim hauv qab no yog suav tias yog qhov txaus ntshai tshwj xeeb rau tus neeg mob noj qab haus huv: pom ob lub zeem muag, xeev siab, ntuav, mob plab, plawv tsis ua haujlwm, mob siab, tso zis tsis txaus, anaphylactic thiab ua xua, tso zis tsaus, suab nrov hauv pob ntseg, hnov qab. poob, tsis qab los noj mov, qaug zog ntau dhau, yellowing ntawm daim tawv nqaij thiab ob lub qhov muag, loog thiab tingling ntawm cov nqaij mos thiab tawv nqaij, photophobia, daim tawv nqaij ua pob, khaus, hoarseness, pulmonary edema, kev coj khaub ncaws tsis xwm yeem, o ntawm lub ntsej muag, caj pas, tes,pob taws. Yog tias koj muaj cov tsos mob saum toj no, koj yuav tsum qhia koj tus kws kho mob tam sim ntawd.
Yuav ua li cas xaiv ib qho analogue ntawm "Itraconazole"
Txhua xyoo ntau thiab ntau tus neeg tau ntsib teeb meem ntawm cov kab mob fungal. Nyob rau tib lub sijhawm, ntau tus neeg mob txiav txim siab tias nws tsis tsim nyog yuav Itraconazole rau lawv cov kev kho mob. Analogues yog pheej yig dua, yog li lawv feem ntau nyiam. Qhov tseeb, kev xaiv ntawm cov tshuaj no lossis nws cov analogues yuav tsum txiav txim siab los ntawm tus kws kho mob uas tuaj koom. Hauv qee qhov xwm txheej tshwj xeeb, kev rov ua tiav ntawm tus neeg mob pab ua tiav tsuas yog Itraconazole. Lwm txoj kev pheej yig, tab sis tsis yog txhua tus ntawm lawv muaj txiaj ntsig zoo li cov tshuaj no.
Dab tsi tuaj yeem hloov Itraconazole? Ointment, analogues ntawm cov tshuaj no nyob rau hauv lwm cov ntaub ntawv ntau npaum yog dav sawv cev nyob rau hauv lub khw muag tshuaj. Cov qauv analogues suav nrog cov tshuaj hauv qab no uas tsim tawm hauv cov ntsiav tshuaj: Irunin, Intramikol, Itrazol, Mikonikhol, Kanditral, Kanazol, Teknazol, Orungal, Rumikoz, Orungamine”, “Orunit”.
Analogues ntawm "Itraconazole" hais txog kev kho mob yog cov tshuaj hauv qab no:
- capsules: Diflucan, Diflazon, Itrazol, Orungal, Rumikoz, Flucostat, Fluconazole, Fungolon;
- tablets: "Atifin", "Binafin", "Ketoconazole", "Fungoterbin", "Exifin", "Nizoral";
- tshuaj pleev, cream, gels: Akriderm, Lamisil Dermagel, Terbizil, Exifin, Mikomax, Mycozoral, Triderm, Fungoterbin, Ketoconazole, Canison", "Lamitel",Candide, Amiklon, Zalain, Canizon, Atifin, Clotrimazole, Lamisil, Ifenek, Lamitel, Terbix, Imidil;
- tswm ciab, tshuaj hauv qhov chaw mos: "Zalain", "Candide", "Canison", "Mikogal", "Imidil".
Reviews
Cov neeg uas tau noj Itraconazole yog dab tsi? Analogues, tshuaj xyuas uas feem ntau tsis zoo, thiab cov tshuaj no nws tus kheej feem ntau tsis coj cov kev xav tau los ntawm kev kho. Nyob rau tib lub sijhawm, muaj ntau tus contraindications thiab cov kev mob tshwm sim ua rau cov tshuaj no txaus ntshai rau kev noj qab haus huv ntawm ntau tus neeg mob. Ntxiv mus, qhov kev pheej hmoo ntawm kev tsis zoo los ntawm kev siv "Itraconazole" thiab nws cov analogues nce ntxiv yog tias cov lus qhia ntawm tus kws kho mob lossis tus kheej noj tshuaj tsis ua raws.
Feem ntau muaj kev tshuaj xyuas tsis zoo txog cov tshuaj "Itraconazole" (tswj tswm ciab). Analogues ntawm cov tshuaj no kuj feem ntau pom tau los ntawm cov neeg mob uas muaj kev ntshai. Qhov no yog vim lub fact tias nyob rau hauv tej rooj plaub, kev kho mob ntawm cov kab mob fungal nrog kev pab los ntawm suppositories yuav tsum tau supplemented los ntawm noj Itraconazole los yog nws analogues nyob rau hauv.