Intranasal - hom tshuaj twg? Intranasal npaj

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Intranasal - hom tshuaj twg? Intranasal npaj
Intranasal - hom tshuaj twg? Intranasal npaj

Video: Intranasal - hom tshuaj twg? Intranasal npaj

Video: Intranasal - hom tshuaj twg? Intranasal npaj
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Muaj ntau ntau txoj hauv kev los qhia txog tshuaj rau hauv tib neeg lub cev. Thaum kaj ntug ntawm cov tshuaj, cov txheej txheem hauv zos tau siv thawj zaug hauv daim ntawv thov, rub, compresses thiab qhov ncauj, nrog rau kev noj cov tshuaj ntau npaum li cas lossis sublingual resorption. Nrog rau kev txhim kho cov tshuaj thiab thev naus laus zis rau kev xa cov tshuaj nquag mus rau lub cev lub cev, ntau txoj hauv kev pib siv.

Lub qhov quav thiab qhov chaw mos suppositories (tswj tswm ciab), ntau cov tshuaj ntsiav thiab tshuaj ntsiav, suav nrog cov coated nrog lub plhaub uas dissolves nrog kua txiv hmab txiv ntoo los yog plab hnyuv enzymes, tshwm sim. Txoj kev txhaj tshuaj: intra- thiab subcutaneous, intramuscular, intravenous thiab intra-arterial, intraosseous. Cov tshuaj yog txhaj rau hauv cov pob qij txha thiab cov kab noj hniav ntawm lub cev.

intranasal zoo li
intranasal zoo li

Txawm hais tias txoj kev yooj yim ntawm kev tswj hwm, kev npaj endotracheal thiab intranasal tau siv tsis ntev los no. Muaj tseeb tiag,Qhov ntswg qhov ntswg twb muaj nyob rau hauv Hippocrates. Txawm li cas los xij, intranasal yog ib txoj hauv kev los tswj cov tshuaj rau kev xa mus rau lwm yam kabmob, thiab tsis yog kev kho mob rau cov mob khaub thuas, thiab cov kev tswj hwm no tau pib siv ob peb xyoos dhau los.

Pab pawg ntawm cov tshuaj intranasal nrog rau cov txiaj ntsig dav dav (systemic)

Ntau qhov kev tshawb fawb tau pom tias kev sib ntaus tawm tsam qhov ntswg qhov ntswg tsis yog vim li cas rau kev qhia tshuaj rau hauv qhov ntswg. Ib tug xov tooj ntawm cov tshuaj uas muaj ib tug systemic nyhuv yog kiag li absorbed los ntawm cov mucous daim nyias nyias ntawm lub qhov ntswg thiab mus txog lawv qhov chaw tam sim ntawd.

Kev tswj hwm Intranasal ua tau rau:

  • H1-antihistamine (antiallergic);
  • Ya-agonists (vasoconstrictor);
  • mast cell membrane stabilizers;
  • serotonergic (muaj ntau yam teebmeem - los ntawm vasoconstriction rau antiallergic);
  • hormonal thiab antihormonal;
  • YNarcotic analgesics;
  • immunomodulators;
  • kho cov pob txha mos thiab cov pob txha cov metabolism;
  • psychostimulants thiab nootropics.
kev tswj hwm intranasal
kev tswj hwm intranasal

Txoj kev tswj hwm intranasal ntawm cov tshuaj

Tau ntev heev, cov tuam txhab tshuaj tau sim daws ob qhov teeb meem tsis txaus ntseeg txog kev siv tshuaj uas muaj cov qauv tshuaj protein. Qhov kev stumbling block yog kev puas tsuaj ntawm cov protein-peptide tivthaiv ntawm cov active tshuaj los ntawm gastric kua txiv thiabplab hnyuv enzymes thaum noj qhov ncauj. Lwm qhov teeb meem yog qhov tshwm sim ntawm thawj zaug dhau los ntawm lub siab - kev sib khi ntawm cov nquag ua haujlwm thiab nws cov excretion.

Cov tshuaj tau pom nyob rau hauv kev siv tshuaj txhaj thiab qhov quav suppositories. Txawm li cas los xij, thawj txoj hauv kev yog tus cwj pwm los ntawm qee qhov kev ua haujlwm nyuaj, ua ke nrog cov kev xav tsis zoo. Thiab qhov thib ob tau hloov mus ua haujlwm tsis txaus vim qhov nqus tau tsawg hauv qhov kawg ntawm lub qhov quav. Qhov kev txiav txim siab tuaj poob nthav. Nws muab tawm tias intranasal yog, zoo li txhaj tshuaj, xws li kev taw qhia, uas ua tiav qhov pib sai ntawm kev kho mob. Thiab nrog rau qhov sib ntxiv ntawm qee cov tshuaj sib xyaw ua ke, tib lub bioavailability siab tau lees paub, uas yog, qhov xav tau ntawm cov khoom xyaw nquag ntawm qhov chaw ntawm nws daim ntawv thov.

anandine qhov muag thiab intranasal tee
anandine qhov muag thiab intranasal tee

Lwm cov cuab yeej muaj txiaj ntsig ntawm kev tswj hwm intranasal tau tshwm sim hauv cov cellular (yav dhau kev nqus mus rau hauv cov ntshav los ntawm cov mucous membrane) nkag mus ntawm cov tshuaj nquag mus rau hauv lub hlwb. Tau txais mus rau thaj chaw olfactory, cov tshuaj xa los ntawm fibers ntawm olfactory thiab trigeminal qab haus huv.

Forms of intranasal npaj

Rau kev taw qhia rau hauv qhov ntswg kab noj hniav, siv tsawg tsawg ntawm cov ntaub ntawv tshuaj. Ua ntej tshaj plaws, nws yog, ntawm chav kawm, qhov ntswg te. Nws muaj peev xwm nqus tau cov hmoov nplej nrog cov qauv zoo. Siv cov tshuaj pleev. Ntau yam kev daws teeb meem los yog decoctions ntawm tshuaj ntsuab rau ntxuav lub qhov ntswg kab noj hniav tsis muaj nyob rau hauv pawg no vim yog luv luv raug raumucous thaum siv.

Cov tshuaj tseem ceeb ntawm cov tshuaj intranasal nrog cov nyhuv system yog tshuaj tsuag qhov ntswg. Lawv muaj nyob rau hauv daim ntawv ntawm compressed cua dispensers los yog nrog ib tug nquag tsuag twj tso kua mis. Ua tsaug rau qee qhov ntim ntawm cov tshuaj tsuag ejection nrog ib lub xovxwm, muaj peev xwm ntawm cov tshuaj tswj tau ntau npaum li cas.

intranasal interferon
intranasal interferon

Tsis tas li, thaum siv cov tshuaj tsuag, muaj cov dej sib xws ntawm qhov ntswg mucosa. Qhov no ua rau muaj kev nqus ntau dua ntawm cov tshuaj, uas ua rau nws cov tshuaj pharmacological ntau ntxiv.

Cov txiaj ntsig tseem ceeb ntawm kev tswj hwm intranasal

Raws li cov lus saum toj no, nws tuaj yeem txiav txim siab qhov txiaj ntsig tseem ceeb uas kev npaj cov tshuaj intranasal muaj. Qhov yooj yim thiab yooj yim ntawm kev tswj hwm, uas tsis tas yuav tsum tau siv cov cuab yeej siv ntxiv thiab kev cob qhia tshwj xeeb, xws li hauv cov txheej txheem txhaj tshuaj, yog qhov tseem ceeb heev los ntawm kev siv cov neeg mob.

anandine intranasal tshuaj
anandine intranasal tshuaj

Los ntawm qhov pom ntawm lub cev thiab tshuaj tshuaj, qhov ua tau ntawm lub hauv paus ua haujlwm ntawm lub hlwb ua ntej. Cov txiaj ntsig zoo tshaj plaws, tshwm sim hauv lub sijhawm luv luv, nrog rau txoj kev txhaj tshuaj ntawm kev tswj hwm, kuj tseem ceeb heev. Vim tsis muaj qhov tshwm sim ntawm thawj zaug dhau los ntawm daim siab, siab bioavailability ntawm cov tshuaj thiab ib tug me me ntawm cov kev phiv tshwm sim yog guaranteed.

Qhov tsis zoo ntawm txoj kev

Los ntawm qhov pom ntawm qhov systemcov nyhuv, qhov teeb meem tseem ceeb yog tswj cov theem ntawm kev kho mob concentration ntawm cov tshuaj nyob rau hauv cov ntshav plasma. Tus neeg sawv cev yog absorbed sai heev thiab ncav cuag qhov siab kawg nkaus hauv lub sijhawm luv luv, yog li kev tswj hwm intranasal tsuas yog siv rau kev kho lub sijhawm luv luv. Kev ua kom ntev ntev tuaj yeem ua tau tsuas yog nrog kev qhia txog cov tshuaj uas cuam tshuam rau lub paj hlwb.

kev npaj intranasal
kev npaj intranasal

Tsis tas li ntawd, kev txhim kho cov tshuaj tiv thaiv hauv zos ntawm qhov ntswg mucosa yog ua tau. Qhov no yog vim lub siab ntau ntawm cov khoom muaj nyob rau hauv cov tshuaj tsuag thiab cov ntsiab lus ntawm cov khoom ntxiv uas ua kom muaj qhov siab tshaj plaws ntawm cov tshuaj los ntawm cov mucosal nto mus rau hauv cov ntshav.

Qhov muaj peev xwm nqus tau los ntawm qhov ntswg kab noj hniav muaj tsawg tsawg ntawm cov tshuaj uas tsim nyog rau lub cev thiab tshuaj lom neeg rau qhov no. Hauv tus neeg mob, qhov nce ntxiv ntawm cov tshuaj nquag ua rau cov nqi tseem ceeb rau kev yuav cov tshuaj tsuag.

YIntranasal immunomodulators

Thaum lub caij so lossis thaum muaj mob khaub thuas, cov tshuaj uas ua rau muaj kev tiv thaiv kab mob hauv lub cev thiab hauv zos tau siv dav rau kev tiv thaiv thiab kev kho mob.

Intranasal interferon yog siv rau kev tiv thaiv kev kub ntxhov thiab kev tiv thaiv.

Nrog ntau qhov kev tshawb fawb, nws tau pom tias txoj hauv kev intranasal ntawm kev tswj hwm ntawm immunomodulators tsis yog tsuas yog tiv thaiv kev nkag mus ntawm cov kab mob pathogenic los ntawm qhov ntswg mucosa. Nws kuj txhawb kev ua haujlwm ntawm nws tus kheej tiv thaiv rog - ua kom muaj zogkev tsim tawm ntawm lawv tus kheej interferons. Txhawm rau txhawb kev tsim cov tshuaj endogenous interferon raws li txoj kev kho mob, cov tshuaj "Anandin" intranasal yog siv.

Hmoob Interferon

Ib hom tshuaj tiv thaiv kab mob tshwj xeeb, muaj kev ua haujlwm tawm tsam feem ntau ntawm cov kab mob ntawm cov kab mob khaub thuas, "Interferon" muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, txhaj tshuaj thiab hmoov rau kev npaj cov tee. Kev tiv thaiv thiab kev kho mob, koj tuaj yeem siv txhua hom kev tso tawm. Tab sis los muab kev tiv thaiv hauv zos, intranasal yog qhov zoo dua. Qhov no, zoo li qhov thaiv tsis pom, yuav tiv thaiv kev nkag mus ntawm cov kab mob tseem ceeb rau hauv cov hlwb ntawm qhov ntswg mucosa. Qhov no yuav ua kom muaj kev sib kis tsawg dua.

Immunostimulator "Anandin", qhov muag thiab intranasal tee

Cov tshuaj tau siv dav vim tias yuav luag tag nrho cov kev mob tshwm sim, kev tsis zoo tshwm sim thiab muaj txiaj ntsig zoo immunostimulating. Ntxiv rau qhov no, nws kuj muaj cov cuab yeej kho qhov txhab, uas yog ib qho tseem ceeb thaum siv hauv daim ntawv ntawm qhov muag tee rau pob txha los yog cov kab mob conjunctival.

Contraindications rau kev siv tsuas yog siv intramuscularly "Anandin". Intranasal drops raug tso cai nyob rau txhua lub hnub nyoog, thaum cev xeeb tub, lactation thiab lwm yam physiological mob los yog kab mob.

anandine intranasal poob
anandine intranasal poob

Ntau zaus ua rau khaus qhov ntswg, txham thiab tso zis ntau dhaumucus tsis yog ib tug kab mob, tab sis ib tug antigen, ua rau ib tug nonspecific tiv thaiv kab mob - ua xua. Hauv kev kho mob ntawm daim ntawv no ntawm rhinitis, intranasal corticosteroids feem ntau siv. Qhov no muaj tseeb tshwj xeeb tshaj yog rau cov neeg uas muaj kev fab tshuaj raws caij nyoog - hay fever.

Thaum lub sijhawm paj ntawm qee cov nroj tsuag, nws tsis txaus rau cov neeg mob no tsuas yog siv cov tshuaj tiv thaiv kab mob, uas feem ntau kuj muaj cov nyhuv sedative. Qhov no tsis tsim nyog thaum tsav tsheb, ua haujlwm nrog cov txheej txheem lossis hauv cov xwm txheej ntawm qhov siab tshaj plaws ntawm lub hlwb. Tom qab ntawd cov tshuaj hormonal hauv zos tau raug sau tseg, uas txo qhov tshwm sim ntawm cov tsos mob yam tsis muaj kev cuam tshuam rau tag nrho cov keeb kwm hormonal.

Intranasal corticosteroids
Intranasal corticosteroids

Kev Tiv Thaiv

Txawm hais tias muaj dav thiab yooj yim zam ntawm cov tshuaj no, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias intranasal yog, zoo li lwm yam, ib qho tshuaj uas yuav tsum tau siv tshwj xeeb raws li kws kho mob qhia, nyob rau hauv ntau npaum li cas, zaus thiab lub sijhawm. ntawm kev tswj hwm.

Ntau zaus muaj cov xwm txheej thaum koj yuav tsum tau noj ob peb tshuaj ib zaug, tsis muaj ib qho twg tuaj yeem muab tso tseg. Yog li ntawd, nws yuav tsum paub seb lawv puas yuav muaj kev cuam tshuam tsis zoo rau lub cev thaum ua ke. Cov lus qhia rau kev siv tsis tuaj yeem suav tag nrho cov kev xaiv rau kev txhim kho kev ua xua. Yog li ntawd, ua ntej noj cov tshuaj xws li suppositories, tshuaj pleev thiab tshuaj tsuag, koj yuav tsum tau sab laj nrog koj.specialist.

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