Cov tshuaj lom degeneration ntawm daim siab yog tus cwj pwm los ntawm kev mob toxicosis hnyav, fatty degeneration thiab necrosis ntawm daim siab hlwb. Sucker piglets raug kev txom nyem los ntawm tus kab mob no, nrog rau weaners thiab gilts, nyob rau lub caij nplooj zeeg thiab lub caij ntuj no. Nyob rau tib lub sijhawm, kev tuag tseem ceeb tau pom txij lub Kaum Ob Hlis mus txog Lub Ib Hlis. Hauv ntau qhov chaw muaj kev lag luam, cov kab mob no tau pom nyob hauv txhua lub sijhawm ntawm lub xyoo.
Etiology hauv tsiaj
Cov kab mob dystrophy ntawm lub siab loj hlob feem ntau nyob rau hauv cov liaj teb uas npua thiab cov nyuj tau noj cov khoom noj tsis zoo rau lub sijhawm ntev thiab khaws cia rau hauv cov xwm txheej uas muaj qhov tsis zoo ntawm microclimate. Lub ntsiab ua rau lom dystrophy ntawm lub cev yog intoxication, uas yog tshwm sim los ntawm kev noj cov khoom lwj thiab pwm cuam tshuam rau cov tsiaj, nrog rau cov khoom uas muaj alkaloids nrog rau saponins thiabmineral tshuaj lom.
Tus kab mob no feem ntau sau tseg hauv thaj chaw uas muaj qhov tsis txaus ntawm cov ntaub ntawv selenium hauv cov av. Qhov ua rau lub siab dystrophy nyob rau hauv cov tsiaj tuaj yeem ua txhaum ntawm cov protein thiab carbohydrate piv hauv cov khoom noj, nrog rau qhov tsis muaj methionine, cystine, choline, thiab, ntxiv rau, vitamin E. Nyob rau hauv cov ntaub ntawv no, ib tug loj tus naj npawb ntawm underoxidized. cov khoom tsim uas muaj tshuaj lom rau lub cev. Tus kab mob kuj tshwm sim nrog kev siv tsis zoo thiab siv tshuaj tua kab mob ntev ntev uas cuam tshuam nrog tetracycline series, thiab kev siv lwm cov tshuaj tua kab mob kuj yog ib qho tseem ceeb hauv nws txoj kev loj hlob.
Cov tshuaj lom uas tuaj nrog zaub mov thiab tsim hauv lub cev tiv thaiv keeb kwm ntawm kev zom zaub mov thiab cov txheej txheem metabolic nruab nrab, tom qab nqus nkag mus rau hauv daim siab. Twb tau nyob hauv lub cev, nyob ntawm qhov ntau npaum li cas thiab lub sijhawm ntawm lawv qhov kev noj haus, ntau yam txheej txheem tshwm sim, piv txwv li, kev ua haujlwm ntawm oxidative enzymes yuav txo qis, kev poob qis hauv glycogen qib tau sau tseg, thiab tib lub sijhawm, fatty infiltrations tsim thiab cov Kev tawg ntawm daim siab hlwb raug kaw, thiab tom qab ntawd - daim siab necrosis.
Fatty infiltrations ua ke nrog cov kab mob hauv nruab nrog cev tshwj xeeb tshaj yog kev vam meej thaum muaj qhov tsis txaus ntawm cov khoom noj ntawm cystine, methionine, choline thiab tocopherol, suav nrog. Qhov tsis muaj lossis tsis muaj peev xwm ntawm cov lipotropic yam no ua rau muaj qhov tseeb tias cov roj ntsha uas tau tsim tshiab tsis koom nrog hauv kev sib txuas ntawm phospholipids, tab sis tso rau hauv daim siab hauv daim ntawv ntawm triglycerides. Rautib cov txheej txheem ntawm deposition ntawm cov rog nyob rau hauv lub cev no ua rau ib tug txo nyob rau hauv cov qib ntawm oxidation raws li ib tug tshwm sim ntawm ib tug txo nyob rau hauv lipolytic kev ua si. Tom ntej no, nrhiav seb dab tsi cuam tshuam qhov tshwm sim ntawm tus kab mob no hauv cov tsiaj.
Ua rau muaj mob hauv nyuj thiab npua
Tus kab mob no feem ntau cuam tshuam rau piglets nrog rau gilts thiab calves thaum lub sij hawm weaning thiab fattening lub sij hawm. Hauv cov chaw ua lag luam uas tshwj xeeb hauv cov tsiaj nyeg fattening, ntawm cov liaj teb thiab cov liaj teb uas cov kev cai noj zaub mov raug ua txhaum cai (cov khoom noj muaj kuab lom tau qhia ntau), tus kab mob kis tau loj heev, ua rau muaj kev puas tsuaj loj vim yog kev quab yuam tua tsiaj thiab tuag.
Cov kab mob siab dystrophy hauv cov nyuj thiab npua tuaj yeem tsim los ntawm lwm yam kab mob (kis, plab hnyuv ntawm ntau lub hauv paus, sepsis), thaum muaj cov txheej txheem ntxiv ntawm kev nqus cov khoom lom rau hauv cov ntshav.
Symptoms
Nyob rau hauv cov npua npua, tus kab mob no feem ntau mob heev thiab tej zaum yuav tshwm sim los ntawm kev ntxhov siab, lub plawv dhia ceev thiab ua tsis taus pa. Tsiaj txhu muaj kev nyuaj siab. Lub cev kub qee zaum nce mus rau 40.8 degrees, thiab tom qab ntawd poob qis thiab ua tsis zoo. Nrog rau lub siab dystrophy nyob rau hauv piglets, yellowness ntawm mucous daim nyias nyias thiab daim tawv nqaij yog tej zaum ua tau nrog rau ntuav, thiab cem quav yog hloov los ntawm raws plab.
Tawm tsam keeb kwm ntawm tag nrho cov no, ib qho loj ntawm bilirubin nkag mus rau hauv cov ntshav ntawm cov tsiaj thiab oliguria yog tsim. Hauv cov zis nrog siabLub ntiajteb txawj nqus muaj bilirubin, urobilin thiab protein. Tawm tsam keeb kwm yav dhau los ntawm kev ua haujlwm tsis txaus ntawm lub plawv hauv cov kab mob siab dystrophy hauv npua thiab nyuj, pob ntseg xiav, tawv nqaij thiab lub plab yog pom. Hom kab mob no feem ntau tuag taus.
Subacute thiab ntev daim ntawv ntawm cov kab mob no tau sau tseg feem ntau ntawm cov piglets weaned, thiab nws yog tus cwj pwm los ntawm cov cim qhia tsawg. Tej zaum yuav muaj kev nyuaj siab ntawm cov xwm txheej nrog rau kev tsis qab los noj mov, qee zaum ntuav thiab raws plab. Qhov kub thiab txias yuav nyob rau hauv ib txwm txwv lossis qis. Jaundice ntawm cov mucous daim nyias nyias thiab daim tawv nqaij nyob rau hauv ib tug ntev chav kawm yog tsis tshua pom.
Diagnosis
Tus kab mob no tau txiav txim siab los ntawm cov ntaub ntawv anamnestic, qhov kev hloov pauv ntawm kev txhim kho ntawm cov tsos mob, ntawm qhov tshwm sim ntawm kev kuaj xyuas cov zaub mov, tso zis, ntshav thiab kev hloov pauv hauv cov kab mob parenchymal.
Kev hloov pauv ntawm lub cev feem ntau nyob ntawm qhov tseem ceeb ntawm haiv neeg. Thaum ntxov ntawm txoj kev loj hlob ntawm tus kab mob, lub siab nyob rau hauv cov tsiaj yog me ntsis loj, nws muaj ib tug flabby kev ntxhib los mos thiab muaj ib tug daj xim. Nrog kev loj hlob ntawm necrosis ntawm parenchyma, flabbiness nrog wrinkling ntawm lub cev yog ntau pronounced, thaum ntxoov ntxoo yog clayey los yog liab. Degenerative hloov nyob rau hauv lub plawv cov leeg thiab ob lub raum tau sau tseg. Lub cev tuaj yeem o, loosened, hyperemic, qee zaum nrog hemorrhages, thiab mucous daim nyias nyias ntawm lub plab zom mov yog them nrog cov kua nplaum tsis pub leej twg paub. Saib xyuas kev yaig thiab ulceration.
Kev kho mob
Ua ntejQhov tseem ceeb tshaj, nws yog ib qho tseem ceeb kom tshem tawm qhov ua rau ntawm tus kab mob. Nrog rau kev loj hlob ntawm cov kab mob siab dystrophy, lub plab thiab cov hnyuv tau ntxuav nrog dej sov los yog kev daws ntawm poov tshuaj permanganate siv cov tshuaj ntsuam xyuas thiab cov tshuaj enema. Sab hauv, 100 grams ntawm castor roj yog qhia, 50 - sunflower, 30 - hemp thiab 100 - linseed. Kev tshaib kev nqhis yog muab rau kaum ob teev. Tsis tas li ntawd, cov tsiaj muaj mob tau noj zaub mov noj (peb tab tom tham txog mis nyuj, skim mis, oatmeal jelly, kua cereals los ntawm oatmeal thiab barley groats, yogurt).
Ntxiv rau, cov kab lis kev cai acidophilic (los ntawm 20 mus rau 40 milliliters) tau muab tshuaj ob zaug rau tsib mus rau xya hnub. Hydrolysin yog txhaj tshuaj subcutaneously, thiab lipotropic Cheebtsam nyob rau hauv daim ntawv ntawm choline chloride, tocopherol acetate thiab methionine yog siv rau qhov ncauj. Nyob rau hauv lub neej yav tom ntej, tsiaj txhu raug xa mus rau kev noj zaub mov ntawm carbohydrates nrog qhov tsim nyog ntawm cov protein, vitamins, amino acids thiab cov khoom xyaw ntxhia.
YGlucose solution
Thaum pib ntawm txoj kev loj hlob ntawm cov kab mob siab dystrophy, kev txhaj tshuaj subcutaneous ntawm kaum feem pua qabzib ntawm qhov ntau npaum li 20 mus rau 50 milliliters yog siv tau, ntxiv rau, sodium selenite yog siv hauv qhov nyiaj ntawm 0.2 milligrams ib kilo. ntawm cov tsiaj hnyav thiab txhaj tshuaj intramuscular ntawm calcium gluconate. Cov tshuaj yog siv ob zaug ib hnub twg, thaum tsis muaj qabzib, mis nyuj nrog qab zib, quav nyab infusion, jelly thiab porridge tuaj yeem muab rau hauv. Yog tias tsim nyog, yuav tsum tau muab tshuaj rau lub plawv.
Kev Tiv Thaiv
Raws li ib feem ntawm kev tiv thaiv, nws yog ib qho tseem ceeb los saib xyuas cov khoom noj muaj txiaj ntsig zoo,kev huv zoo ntawm kev pub noj, thiab tib lub sijhawm cov xwm txheej ntawm kev khaws cov nyuj thiab npua. Cov khoom noj muaj pes tsawg leeg yuav tsum suav nrog, raws li cov qauv uas twb muaj lawm rau txhua hnub nyoog, cov amino acids tseem ceeb hauv daim ntawv ntawm lysine, methionine, cystine, nrog rau cov zaub mov thiab ntau cov vitamins. Ib qho khoom noj yuav tsum tau tshuaj xyuas tsis tu ncua kom muaj tshuaj lom.
Nyob hauv cov teb tsis zoo, rau kev tiv thaiv, kev txhaj tshuaj intramuscular ntawm 0.1% tshuaj sodium selenite tau pom zoo (ib zaug nees nkaum tsib hnub ua ntej farrowing ntawm tus nqi ntawm 0.1 milligram ib kilo ntawm tsiaj hnyav).
Calf autopsy raws tu qauv
Raws li txoj cai calf autopsy, nrog rau lub siab dystrophy, tus tsiaj muaj mob muaj rog degeneration thiab cell necrosis. Lub cev, raws li txoj cai, yog loj nyob rau hauv ntim, lub capsule yog unevenly xim thiab nruj, thiab tiv thaiv lub keeb kwm yav dhau muaj foci ntawm ib tug yellowish xim ntawm ib tug flabby sib xws, uas yog yooj yim puas los ntawm lub siab. Portal lymph nodes yam tsis muaj kev hloov pauv. Lub gallbladder tau sau nrog cov kua tsib tuab tuab, thiab nws cov mucous membrane yog velvety, patency ntawm excretory ducts tsis muaj kev cuam tshuam. Raws li cov ntaub ntawv autopsy, nws tuaj yeem txiav txim siab tias tus tsiaj tuag yog vim mob siab rau lub siab dystrophy.
Ntse ntawm pathology
Lub pathological anatomy ntawm toxic siab dystrophy nws txawv nyob ntawm seb lub sij hawm ntawm tus kab mob. Nyob rau hauv tag nrho, tus kab mob yuav siv li peb lub lis piam. Thaum ntxovlub cev yog loj thiab flabby. Nws yuav siv sij hawm ib tug daj xim. Tom qab ntawd lub capsule yuav wrinkled. Cov ntaub so ntswg feem ntau yog av nplaum zoo li. Microscopically, nyob rau hauv thawj hnub ntawm tus kab mob, fatty degeneration ntawm hepatocytes yog muab sau tseg, uas yog sai hloov los ntawm necrosis thiab autolytic decay nrog tsim cov rog-protein detritus, nyob rau hauv uas muaj crystals ntawm tyrosine thiab leucine.
Kev nce qib, qhov hloov pauv necrotic ntes txhua ntu ntawm lobules thaum kawg ntawm lub lim tiam thib ob ntawm tus kabmob. Tsuas yog nyob rau hauv lawv qhov periphery tseem tshuav ib daim hlab nqaim ntawm hepatocytes. Cov kev hloov hauv lub cev no qhia txog theem ntawm daj dystrophy. Hauv peb lub lis piam ntawm tus kab mob, daim siab yuav txo qis thiab ua liab. Qhov no yog vim lub fact tias cov rog-protein detritus ntawm lub lobules dhau mus rau cov txheej txheem ntawm phagocytosis thiab yog resorbed.
Macro npaj
Macropreparation ntawm toxic siab dystrophy yog ib tug swb ntawm ib yam khoom nyob rau hauv, npaj rau kev tshawb fawb nyob rau hauv ib tug microscope. Los ntawm saum toj no, cov khoom no feem ntau yog npog nrog lub khob nyias nyias. Qhov luaj li cas ntawm cov slides yog 25 los ntawm 75 millimeters, thiab lawv cov thickness yog standardized, uas zoo heev pab txhawb kev cia thiab tuav cov twj paj nruag.
Zoo kawg
Yog li, tus kab mob cuam tshuam loj heev necrosis. Raws li txoj cai, qhov no yog, ua ntej ntawm tag nrho cov, ib tug mob, feem ntau tsis tshua muaj mob pathological mob, uas nyob rau hauv cov tsiaj yog yus muaj los ntawm loj heev necrosis ntawm lub cev thiab nws insufficiency. Tus kab mob no tshwm sim feem ntau nrog exogenous thiabendogenous intoxications. Nws kuj tau ntsib nyob rau hauv kab mob siab viral raws li ib qho kev qhia ntawm nws daim ntawv malignant. Hauv cov kab mob pathogenesis, qhov tseem ceeb yog txuas nrog cov teebmeem hepatotoxic ntawm tus kab mob. Kev tsis haum tshuaj qee zaum ua lub luag haujlwm.
