Txawm tias muaj kev cuam tshuam me me hauv lub hlwb ua haujlwm sai lossis tom qab dhau los ua cov kab mob loj. Ib qho tsis kaj siab thiab txaus ntshai tshaj plaws yog qaug dab peg. Txog tam sim no, tsis muaj cov tshuaj uas muaj peev xwm tswj tau thiab tua cov mob no. Xws li cov tshuaj tau tsim tsuas yog nyob rau hauv nruab nrab ntawm lub xyoo pua xeem, piv txwv li, Depakin. Cov tshuaj no yog dab tsi? Nws yog cov tshuaj muaj zog, yog li koj tsis tuaj yeem siv nws ntawm koj tus kheej kev txiav txim siab. Yog tias noj tsis raug, cov kev mob tshwm sim ntawm "Depakine" yuav tshwm sim.
Cia peb piav txog cov cuab yeej no kom ntxaws ntxiv. "Depakine" yog ib qho tshuaj antiepileptic thiab anticonvulsant tshuaj. Nws yog nquag siv nyob rau hauv txhua hom mob vwm. Cov tshuaj kuj txo cov kev xav ntawm ntshai thiab ntshai, txhim kho lub siab lub ntsws ntawm cov neeg mob, yog li qhia nws tranquilizing zog. "Depakine" yog siv nyob rau hauv kev kho mob ntawm qaug dab peg, manifested nyob rau hauv daim ntawv ntawm qaug dab peg, convulsive syndromes, cwj pwm tsis zoo, bipolar.kev puas siab puas ntsws, nrog rau cov tsos mob ntawm convulsions thiab tics nyob rau hauv cov me nyuam. Cov kev mob tshwm sim ntawm "Depakine", uas tau sau tseg hauv nws cov lus qhia, tuaj yeem pom lawv tus kheej los ntawm ntau lub cev. Yog li ntawd, noj tshuaj yuav tsum tau pom zoo nrog tus kws kho mob.
Cov ntawv sau thiab tso tawm
"Depakin" yog tsim nyob rau hauv cov ntaub ntawv hauv qab no:
- Syrup rau qhov ncauj siv hauv vials ntawm 150 ml. Lub ntim ntawm cov tshuaj nyob rau hauv cov khoom muaj ib tug dosing ob-sided diav. Lub syrup yog tov nrog tej kua ua ntej noj.
- Depakine Enteric zaj duab xis-coated ntsiav tshuaj, 100 daim ib pob. Ib ntsiav tshuaj muaj 300 mg ntawm cov khoom xyaw nquag.
- ntsiav tshuaj "Depakin Chrono" 30 lossis 100 daim ib pob. Ib daim muaj cov tshuaj nquag 300 mg lossis 500. "Depakine Chrono" hauv Latin - DEPAKINE CHRONO.
- Granules "Depakin Chronosphere". Lawv muaj nyob rau hauv lub hnab ntawm peb caug los yog tsib caug daim ib pob. Ib lub hnab ntawm "Depakine Chronosphere" yuav muaj 100, 250, 500, 750 lossis 1000 mg ntawm cov khoom xyaw nquag. Qhov siab tshaj plaws ntawm cov tshuaj nquag yog txiav txim siab hauv cov ntshav xya teev tom qab siv cov tshuaj. Kev faib tawm ntawm cov tshuaj nyob rau hauv cov ntaub so ntswg tshwm sim nyob rau tib lub sij hawm. Cov menyuam yaus raug qhia kom haus cov tshuaj no nrog cov pluas noj, nchuav cov granules rau hauv cov dej haus (piv txwv li, hauv cov txiv hmab txiv ntoo lossis kua txiv hmab txiv ntoo). Tsis txhob sib tov Depakine Chronosphere nrog cov zaub mov kub lossis kua.pom zoo. Yog tias cov khoom raug muab rau tus menyuam mos, nws yuav tsum tsis txhob muab nchuav rau hauv lub raj mis me nyuam. Tom qab sib tov Depakine Chronosphere granules nrog dej ntawm chav tsev kub, cov tshuaj npaj yuav tsum tau noj tam sim ntawd. Nws tsis pom zoo kom zom cov granules. Tsis txhob khaws cov tshuaj npaj tau ntev (ntau tshaj li ib nrab teev). Yog hais tias cov ntsiab lus tshuaj yog poured rau hauv ib khob, ces cov khoom yuav tsum tau zoo sib tov ua ntej siv, vim hais tias cov granules ntawm cov tshuaj feem ntau nyob rau hauv qab ntawm lub nkoj. Kev mob tshwm sim ntawm "Depakine Chronosphere" yuav piav qhia hauv qab no.
- Power rau txhaj. Rau ib lub raj mis ntawm 400 mg sodium valproate thiab 1 ampoule dej rau txhaj.
Cov tshuaj "Depakine Chrono" (ATC code N03AG01)
Cov tshuaj no tuaj nyob rau hauv daim ntawv ntawm oblong dawb ntsiav tshuaj tau qhab nia ntawm ob sab. Lawv tsis muaj ntxhiab tsw thiab tsis kaj siab, tab sis lawv tseem tsis tas yuav chewed. Ib koob ntawm "Depakine Chrono" 500 (ATC code N03AG01) muaj cov khoom xyaw nquag hauv daim ntawv ntawm sodium valproate 333 mg thiab valproic acid 145 mg. Ib koob ntawm "Depakine Chrono" 300 muaj cov khoom xyaw nquag hauv daim ntawv ntawm sodium valproate 199.8 mg thiab valproic acid 87.0 mg. Kev mob tshwm sim ntawm "Depakine Chrono" 300 thiab lwm yam tshuaj yuav raug piav qhia hauv qab no.
Kev noj tshuaj thiab kev siv ntawm "Depakine Chrono"
Kev nqus ntawm Depakine Chrono ntsiav tshuaj pib tam sim tom qab lawv nkag mus rau hauv plab. Lawv muaj kev ua haujlwm ntev. Qhov no ua rau qhov tsis muaj qhov siab tshaj plaws ntawm cov khoom siv hauv cov ntshav plasma thiab pab txhawb rautswj cov kev xav tau ntawm cov tshuaj nquag rau lub sijhawm ntev. Raws li cov lus qhia rau kev siv "Depakine Chrono", nws yuav tsum tau noj raws li nram no:
- Tshuaj noj ob lossis peb zaug hauv ib hnub. Cov tshuaj tuaj yeem ntxuav nrog cov kua me me. Cov ntsiav tshuaj yuav tsum nqos yam tsis tau zom.
- Cov tshuaj no yog muab rau cov neeg laus thiab cov menyuam yaus uas hnyav tshaj kaum xya kilograms.
- Tus nqi txhua hnub ntawm cov tshuaj yog txiav txim siab raws li hnub nyoog, qhov hnyav ntawm tus neeg mob. Cov menyuam yaus hnub nyoog qis dua 6 xyoo yuav tsum tsis txhob noj cov tshuaj hauv cov ntsiav tshuaj. Thaum sau ib koob tshuaj, nws yuav tsum tau coj mus rau hauv tus account lub spectrum ntawm tus kheej rhiab heev rau valproate. Ib qho kev sib raug zoo tau pom nyob nruab nrab ntawm cov koob tshuaj ib hnub twg, qhov concentration ntawm cov tshuaj hauv cov ntshav thiab cov nyhuv kho. Kev txiav txim siab ntawm qib ntawm cov tshuaj nquag "Depakine" hauv cov ntshav plasma tuaj yeem yog ib qho ntxiv rau kev saib xyuas tus neeg mob hauv cov xwm txheej uas tsis muaj kev tswj hwm lossis muaj kev xav tias muaj kev phiv ntawm "Depakine". Qhov ntau ntawm kev ua tau zoo ntawm cov tshuaj feem ntau yog los ntawm 40 mus rau 100 mg / l.
- koob tshuaj thawj zaug yuav tsum yog 5 mus rau 15mg / kg ib hnub, maj mam nce qhov koob tshuaj no los ntawm 5mg / kg nyob rau lub sijhawm ntawm xya hnub mus rau qhov tsim nyog.
- Rau cov menyuam hnub nyoog 6 txog 14 xyoos, qhov siab tshaj plaws ntawm cov tshuaj ib hnub yog 30 mg / kg. Qhov kev suav no yog qhov tseeb rau lub cev hnyav txog li 30-40 kg.
- Rau cov tub ntxhais hluas hnub nyoog 14 xyoos thiab laus dua, qhov koob tshuaj yog 25mg / kg (rau cov neeg mob hnyav ntawm 40 txog 60kg).
- Rau cov neeg laus thiab cov tub ntxhais hluas uas hnyav dua 60 kg, qhov koob tshuaj yog 20mg/kg.
- Yog tias qhov zaus ntawm kev qaug dab peg tsis tswj tau ntawm cov koob tshuaj no, lawv tuaj yeem nce ntxiv nrog kev saib xyuas nruj ntawm tus neeg mob tus mob. Txawm li cas los xij, nws yuav tsum nco ntsoov tias cov txiaj ntsig ntawm cov tshuaj yuav pom tau tom qab 4-6 lub lis piam tom qab pib kev tswj hwm. Yog li ntawd, nws tsis pom zoo kom nce koob tshuaj ua ntej lub sijhawm no.
- Nyob rau hauv cov neeg mob laus, qhov koob tshuaj yuav tsum tau teem raws li kev noj qab haus huv ntawm cov neeg mob uas muaj kab mob.
"Depakine Chrono" muaj ib daim ntawv ntawm maj mam tso tawm ntawm cov khoom nquag, uas ua rau txo qis hauv nws cov concentration hauv cov ntshav plasma thiab tswj nws thaum nruab hnub ntawm tib theem.
Indications rau noj "Depakin Chrono"
Cov tshuaj tau sau rau cov neeg laus thiab menyuam yaus ua kev kho mob:
- qaug dab peg.
- Forms of Child Elepsy.
- ib nrab qaug qaug dab peg.
- Kev puas siab puas ntsws Bipolar thiab lawv cov kev tiv thaiv.
"Depakin Chrono" yog hais txog neuroleptics lossis antipsychotics. Cov no yog cov tshuaj uas muaj dav heev ntawm kev tiv thaiv kev ua si. Lawv lub luag haujlwm tseem ceeb nyob hauv lub peev xwm los tswj kev puas siab puas ntsws thiab tshem tawm lossis txo qis nws qhov tshwm sim xws li kev ntxhov siab, delirium, ntxhov siab vim thiab ntshai. Ntawm qhov kev ceeb toom tshwj xeeb yog tias neuroleptics (antipsychotics) muaj ntau yam teebmeem:
- Kev ua haujlwm.
- tshuaj tsaug zog.
- Antidepressive.
- kev coj cwj pwm zoo.
Neuroleptics kuj tau siv zoo hauv kev kho mob neurotic:
- Kev xav tsis thoob.
- Kev hloov pauv.
- Ntse thiab ntev ntev kev ntshai.
- Ntsuag pw tsaug zog.
- Hloov tsis muaj laj thawj.
- xeev kev ua haujlwm qis.
- Apathy.
- Cov kab mob digestive ntawm keeb kwm ntawm neurosis.
Qhia tshuaj kho cov menyuam mos
Cov teebmeem ntawm "Depakine Chrono" hauv cov menyuam yaus tshwm sim ntau zaus. Ib qho tseem ceeb hauv kev kho mob yog qhov tsis muaj peev xwm paub qhov txawv ntawm kev qaug dab peg los ntawm cov neeg hauv zos. Epilepsy Syndrome hauv cov menyuam yaus tuaj yeem sib txawv heev. Nws yog ib qho tseem ceeb uas cov tshuaj siv tawm tsam qaug dab peg muaj qhov dav dav ntawm kev ua. Hauv peb lub tebchaws, tsuas yog siv cov tshuaj benzodiazepine ntev ntev ("Gidazepam", "Diazepam", "Clonazepam" thiab lwm yam) uas tsis tau qhia lawv cov txiaj ntsig hauv txhua kis.
Kev tshuaj xyuas txog "Depakine" tsis meej. Cov niam txiv ntawm cov neeg mob hluas qhia txog nws qhov zoo thiab qhov tsis zoo. Ntau cov kev mob tshwm sim tau raug sau tseg los ntawm leej niam thiab leej txiv ntawm cov menyuam mos uas tau sau cov tshuaj no. Raws li cov niam txiv cov lus teb, peb tuaj yeem xaus tias yog tias koj tus menyuam tsis tau kuaj pom tias muaj mob vwm, ces nws yog qhov zoo dua kom tsis txhob noj Depakine.
kev tawm tsam tsis zoo
Hmoov tsis, cov tshuaj no muaj ntau ntawm lawv. Yog li ntawd, lawv txoj kev kho mobyuav tsum tau ua raws li kev saib xyuas ntawm tus kws kho mob. Cia peb xav txog dab tsi tshwm sim tuaj yeem tshwm sim thaum noj Depakine los ntawm ntau lub cev:
Nervous system:
- Tshem.
- Stupor.
- Zoo siab.
- Txhawj xeeb.
- Headache.
- kiv taub hau (tshwm sim thaum muab tso rau hauv cov hlab ntsha).
- Memory gaps.
- Nyob zoo.
- Encephalopathy.
- Qee zaum coma.
- Ataxia.
- Reversible dementia.
Yog tias cov tsos mob no tshwm sim, qhov koob tshuaj yuav tsum rov xav dua.
Hematopoietic system:
- Anemia.
- Leukopenia.
- Thrombocytopenia.
- Neutropenia.
- YMacrocytosis.
- Agranulocytosis.
- Hypoplasia (los yog aplasia) ntawm erythrocytes.
- YMicrocytic anemia.
Yog li no, tshuaj raug tso tseg.
ntshav txhaws:
- Bleeding.
- Spontaneous akhymosis.
- Increased INR.
- Nyob rau hauv lub sijhawm thrombosed.
- Hemorrhages.
Hauv cov xwm txheej no, txhawm rau tshem tawm cov kev mob tshwm sim ntawm Depakine, cov tshuaj raug tshem tawm, thiab tus neeg mob raug kuaj xyuas.
Psyche:
- Kev tsis sib haum xeeb.
- kev tsis sib haum xeeb.
- Kev npam.
- xeev kev nyuaj siab.
- Txuag kev muaj peev xwm kawm.
- Psychomotor hyperactivity.
Yuav tsum tau saib xyuas tus neeg mob tus mob thiab kho qhov koob tshuaj. Raws li kev txheeb xyuas txog"Depakine", cov kev mob tshwm sim hauv cov menyuam yaus feem ntau nrog kev puas siab puas ntsws, nrog rau kev ua haujlwm tsis zoo ntawm lub plab zom mov.
YDigestion system:
- Nausea (ntau heev).
- YGingival hyperplasia.
- Zoo plab (feem ntau).
- mob plab (common).
Kev rho tawm cov tshuaj hauv qhov no tsis tas yuav tsum tau.
Tsis tshua muaj:
- Pancreatitis (qee qhov tuag taus).
- mob plab.
- Anorexia.
Nws pom zoo kom haus cov tshuaj thaum noj mov kom txo tau cov tsos mob no.
Urinary system:
- Enuresis.
- Fanconi syndrome.
- Tubulointerstitial nephritis.
Immune system:
- YUrticaria.
- Angioedema.
- Drug Rash Syndrome.
Skin:
- khaus khaus (feem ntau).
- Alopecia.
- Rash.
- Erythema multiforme.
- Stevens-Johnson syndrome.
- Ntxhais, plaub hau tsis zoo.
musculoskeletal system:
- Osteopenia.
- Osteoporosis.
- Fractures (vim txo cov ntaub so ntswg ntxhia ceev).
- YSystemic lupus erythematosus.
- YRhabdomyolysis.
YEndocrine system:
- YHyperandrogenism.
- pob txuv.
- Syndrome of inappropriate secretion of ADH.
- Hypothyroidism.
- Alopecia (txiv neej hom).
Lwm kev ua txhaum cai:
- Hnov thiab tsis pom kev.
- Failures inlub siab ua haujlwm.
- Hypothermia.
- Qhov tshwm sim ntawm cov qog (cysts, polyps).
- Galactorrhea.
- Lub mis loj.
- polycystic zes qe menyuam
- Infertility (hauv txiv neej).
- Metabolic ntshawv siab.
- Nco qab qab los.
- Nyhav nce.
YContraindications
Txhawm rau tshem tawm cov kev mob tshwm sim ntawm "Depakine", koj yuav tsum paub koj tus kheej nrog ntau qhov kev txwv tsis pub noj cov tshuaj no:
- Ua kom nkag siab zoo rau cov khoom xyaw tshuaj xws li valproate, divalproate lossis lwm yam khoom xyaw hauv cov tshuaj nquag.
- kab mob siab, mob hnyav lossis mob ntev.
- Lwm kab mob siab ntawm tus neeg mob lossis cov txheeb ze.
- Tsev neeg tuag vim kab mob siab thaum siv valproic acid.
- Hepatic perforation.
- Nyob rau hauv lub xub ntiag ntawm kev ua haujlwm ntawm tus neeg mob lub siab. Raws li kev txheeb xyuas, cov kev mob tshwm sim ntawm "Depakine" tawm tsam keeb kwm ntawm daim siab pathologies hauv cov menyuam yaus ua rau ntau dua li cov neeg laus. Cov pab pawg muaj kev pheej hmoo siab yog cov menyuam yaus hnub nyoog qis dua peb xyoos. Thaum muaj hnub nyoog peb xyoos, qhov tshwm sim ntawm cov teeb meem no yog me ntsis txo thiab maj mam txo nrog cov me nyuam loj hlob tuaj. Lub siab ua haujlwm tsis zoo feem ntau pom nyob rau thawj rau lub hlis ntawm kev kho mob, feem ntau nyob nruab nrab ntawm lub lis piam thib ob thiab kaum ob, thiab feem ntau yog thaum cov tshuaj tiv thaiv kab mob sib xyaw ua ke. Thaum thawj rau lub hlis ntawm kev kho mob, nws yuav tsum tau ua tib zoo saib xyuas kev ua haujlwm ntawm daim siab. Yog hais tias tsawg heev ntawm prothrombin, fibrinogen thiabLwm yam tsis zoo, qhov nce ntawm bilirubin thiab hepatic transaminases, kev kho tshuaj yuav tsum tau txiav.
- mob pancreas. Cov teeb meem nyuaj ntawm tus mob pancreatitis qee zaum tau sau tseg, hmoov tsis zoo, qee zaum kev tuag raug kaw thaum siv tshuaj nrog valproic acid. Cov lus tseeb no tau pom nyob rau hauv cov neeg mob uas muaj hnub nyoog sib txawv thiab lub sijhawm ntawm kev kho mob, txawm hais tias nws tsim nyog sau cia tias qhov tshwm sim ntawm kev mob ntawm tus txiav txiav txo qis nrog cov hnub nyoog ntawm cov neeg mob. Insufficiency ntawm daim siab thaum lub sij hawm inflammatory txheej txheem ua rau kom muaj kev pheej hmoo ntawm kev tuag ntawm tus neeg mob. Nws yuav tsum tau muab sau tseg tias nyob rau hauv kev kho mob ntawm "Depakine" tej zaum yuav muaj ib tug me ntsis nce nyob rau hauv cov theem ntawm transaminases. Tom qab ntawd cov neeg mob tau hais kom ua qhov kev ntsuam xyuas dav dav ntawm lub cev hauv chav kuaj txhawm rau txhawm rau txheeb xyuas qhov ntau npaum li cas ntawm cov tshuaj, yog tias xav tau los ntawm kev tshuaj xyuas. Tsis tas li ntawd, nws yuav tsum tau rov kuaj dua, nyob ntawm qhov hloov pauv ntawm cov tsos mob. Rau cov menyuam yaus hnub nyoog qis dua peb xyoos, kev siv valproate hauv kev kho mob monotherapy yog pom zoo, tab sis ua ntej pib kho, qhov txiaj ntsig tiag tiag ntawm kev noj nws cuam tshuam txog qhov yuav tshwm sim ntawm daim siab lossis kab mob pancreatic yuav tsum raug soj ntsuam. Ua ntej pib kho, yuav tsum tau kuaj ntshav. Rau qhov mob plab thiab cov tsos mob xws li xeev siab, ntuav, tsis txhob noj tshuaj thiab hloov mus rau lwm txoj kev kho mob.
- ComplexHauv cov neeg mob lub raum tsis txaus, nws raug nquahu kom coj mus rau hauv tus account qhov nce ntxiv ntawm cov tshuaj dawb-dawb valproic acid hauv cov ntshav thiab xaiv cov tshuaj tsawg kawg nkaus uas tsim nyog.
- Kab mob cuam tshuam nrog cov xim tsis zoo metabolism (porphyria).
- siv nrog tshuaj siv los tiv thaiv lossis kho malaria uas muaj mefloquine.
- Kev txais tos ib txhij nrog St. John's wort.
- Cov tshuaj no tsis pom zoo siv nrog rau lwm cov tshuaj qaug dab peg uas muaj lamotrigine.
- YSystemic lupus erythematosus.
- History of diabetes mellitus.
- Thaum kho nrog carbapinems (rau mitochondrial ailments).
- Cov menyuam yaus hnub nyoog qis dua rau xyoo yog qhov txwv tsis pub noj cov tshuaj hauv daim ntawv ntsiav tshuaj, vim tias muaj peev xwm nkag mus rau hauv txoj hlab pa thaum noj tshuaj.
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Hauv cov poj niam, "Depakine" tuaj yeem ua rau muaj kev phiv thaum lub sijhawm yug menyuam. Txawm li cas los xij, qhov tshwm sim nyob rau lub sijhawm no ntawm kev qaug dab peg tuaj yeem ua rau tuag ntawm leej niam thiab tus menyuam hauv plab. Yog li ntawd, kev sau tshuaj kho mob, tus kws kho mob yuav tsum sib piv cov kev pheej hmoo uas tshwm sim.
Cov tshuaj nquag valproate tau tshaj tawm tias muaj cov teebmeem hauv qab no rau kev loj hlob ntawm fetal:
- Ntau zaus, nruab nrab ntawm ib thiab ob feem pua ntawm cov neeg mob, kev txhim kho neural tube cuam tshuam.
- Kev txhim kho tsis zoo ntawm lub ntsej muag thiab kev ua phemkev loj hlob ntawm caj npab thiab txhais ceg (ua kom luv ntawm cov ceg).
- Txhim kho lub plawv tsis xws luag thiab vascular system.
Txhawm rau zam cov kev mob tshwm sim los ntawm "Depakine" hauv cov poj niam, cov tshuaj tuaj yeem raug txiav txim los ntawm kws kho mob thaum nqa tus menyuam tsuas yog thaum qhov kev xav tau rau leej niam uas xav tau ntau dua qhov kev pheej hmoo rau tus menyuam. Yog hais tias ib tug poj niam tsuas yog npaj yuav xeeb tub, ces nws yuav tsum rov xav txog cov kev qhia rau kev kho mob ntawm cov mob vwm. Thaum cev xeeb tub, tsis txhob cuam tshuam kev kho mob vwm nrog valproate yog tias nws ua tau zoo. Hauv cov xwm txheej zoo li no, cov kws kho mob tau qhia kom txo qis kom tsawg kawg ntawm cov koob tshuaj zoo ib hnub, uas yuav tsum tau muab faib ua ob peb koob tshuaj. Ntxiv nrog rau cov kev kho mob uas twb muaj lawm, folic acid yuav raug sau tseg, vim tias nws tuaj yeem txo qhov kev pheej hmoo ntawm kev tsim cov hlab ntsha neural los ntawm ob peb zaug.
Kev noj "Depakine" cov kev mob tshwm sim rau tus menyuam mos tuaj yeem yog nyob rau hauv daim ntawv ntawm hemorrhagic syndrome. Hmoov tsis zoo, cov xwm txheej ntawm kev sib kis ntawm afibrinogenemia nrog rau qhov ua rau tuag taus kuj tau sau tseg. Tsis tas li ntawd, hauv cov menyuam yaus raug valproic acid nyob rau hauv lub tsev menyuam, cov teebmeem hauv qab no tau sau tseg:
- Txhob mloog.
- Autism.
- Kev txhim kho qeeb.
- Teeb meem nrog kev nco thiab kev kawm.
Txhua yam kev pheej hmoo no qis dua yog tias tus poj niam tau kho nrog valproic acid monotherapy.
Kev nkag mus ntawm valproate rau hauv cov kua mis yog qhov tsawg heev, nrog rau qhov ntau ntawm ib thiab kaum feem pua ntawm cov tshuaj qib ntshav. yav tom ntej niamTej zaum yuav npaj pub mis niam thaum lub sij hawm Depakine monotherapy, tab sis qhov tshwm sim ntawm kev phiv tshuaj, tshwj xeeb tshaj yog hematological ntshawv siab, tsis tuaj yeem txiav tawm. Feem ntau, cov kws kho mob qhia kom hloov cov tshuaj no nrog kev nyab xeeb dua analogue lossis hloov tus menyuam mus rau kev pub mis ntxiv.
Puas yog xeev siab tuaj yeem ua rau cov poj niam ua qhov tshwm sim ntawm "Depakine"? Cov lus teb yog yog. Kev xeev siab yog qhov tshwm sim tsis zoo tshaj plaws ntawm lub cev rau volproic acid. Qhov no kuj pom nyob rau hauv cov me nyuam mos. Hauv cov poj niam cev xeeb tub, xeev siab tuaj yeem nce ntxiv thaum muaj toxicosis. Feem ntau nws provokes profuse ntuav, tsis qab los noj mov, dav deterioration.
Qee yam ntawm kev noj Depakin Chrono
Nyob rau hauv rooj plaub uas tus neeg mob hloov los ntawm cov ntsiav tshuaj ntawm cov tshuaj uas tsis ua haujlwm ntev ntawm valproate mus rau kev noj "Depakine Chrono", nws yuav tsum tau tswj hwm qhov ntau npaum li cas ib hnub. Thaum hloov lwm yam tshuaj antiepileptic nrog Depakin Chrono, qhov kev hloov pauv yuav tsum tau saib xyuas, ua kom maj mam, ncav cuag qhov xav tau ntawm cov tshuaj nquag hauv ob lub lis piam. Nyob rau hauv cov ntaub ntawv no, nws yog ib qhov tsim nyog los tsom rau lub xeev ntawm tus neeg, kom tshem tawm cov tshuaj yav dhau los tsis tam sim ntawd, tab sis maj mam txo nws cov koob tshuaj. Tom qab qhov kawg tshem tawm ntawm cov tshuaj yav dhau los rau 6 lub lis piam, nws yuav tsum tau saib xyuas tus nqi ntawm valproic acid hauv tus neeg mob cov ntshav. Yog tias tsim nyog, cov koob tshuaj ntawm nws qhov txais tos raug txo.
Rau cov neeg tsis noj lwm yam tshuaj, koob tshuaj yuav tsum tau nce ntxiv tom qab ob lossis peb hnub kom ncav cuag qhov xav tau.tshuaj rau txog xya hnub. Yog tias tsim nyog, kev sib xyaw ua ke nrog lwm cov tshuaj yuav tsum tau tswj hwm hauv theem, raws li cov lus pom zoo ntawm tus kws kho mob uas tuaj koom txog cov tshuaj "Depakine".
Ntau tshaj
Kev tshwm sim ntawm kev noj ntau dhau ntawm "Depakine":
- Coma mob (cov leeg nqaij hypotonia, acidosis, ua pa tsis ua haujlwm, txo qis ntshav siab).
- Intracranial hypertension (nrog cerebral edema).
- Hypernatremia.
Tsheb thauj neeg mob rau kev noj tshuaj ntau dhau hauv tsev kho mob yuav tsum ua raws li hauv qab no:
- Yog tias "Depakine" nkag mus rau hauv, tom qab ntawd nws yuav tsum ua kom lub plab zom mov, uas yog siv tau li ntawm kaum ob teev tom qab noj tshuaj.
- Txhawm rau txo qhov nqus ntawm valproic acid, ib qho adsorbent tau qhia. Piv txwv li, activated carbon.
- Yuav tsum tau saib xyuas ntawm tus kws kho mob rau tus neeg mob lub siab, vascular thiab ua pa, siab thiab txiav.
- Txhob tso zis kom zoo.
- Lub sijhawm rov qab los tom qab noj ntau dhau lawm, yuav tsum tau npaj tshuaj ntsuab tshwj xeeb kom rov tsim cov hlwb hlwb.
- Kev noj zaub mov tsis muaj rog thiab cov roj cholesterol tsawg pom.
- Kev lim ntshav yuav tsum tau rau qhov mob hnyav heev ntawm kev noj tshuaj ntau dhau.
Txhawm rau tiv thaiv kev lom koj xav tau:
- Noj cov tshuaj raws li tus kws kho mob tau sau tseg, ua ntu zus, ua raws li txoj cai.
- Tshem tawm txais tosCov tshuaj muaj valproic acid kom tsis txhob noj ntau dhau.
- Vim qhov muaj feem cuam tshuam rau tus mob pancreatitis, siv cov tshuaj hauv cov menyuam yaus hnub nyoog qis dua peb xyoos, tsuas yog tom qab ntsuas qhov kev txiav txim siab ntawm qhov tshwm sim.
- Kiav tshuaj kom deb ntawm menyuam yaus.
- Thaum cov kev mob tshwm sim ntawm "Depakia" xav tau kev kuaj mob hauv tsev kho mob.
Kev tuag los ntawm kev noj ntau dhau ntawm "Depakine" tau pom, tab sis tsis ntau zaus. Lawv feem ntau tshwm sim yog tias tus neeg mob tsis tau resuscitation raws sijhawm.
Kev sib tham nrog lwm yam tshuaj
"Depakine Chrono" yuav tsum tsis txhob siv thaum siv cov tshuaj sib xyaw ua ke:
- kev tswj hwm ib txhij nrog cov tshuaj muaj mefloquine. Kev sib xyaw ua ke ntawm cov tshuaj no muaj kev pheej hmoo ntawm qaug dab peg hauv cov neeg mob qaug dab peg vim muaj cov metabolism ntawm valproic acid ntau ntxiv thiab kev ua kom tsis haum ntawm mefloquine.
- Cov teebmeem ntawm "Depakine Chrono" 300 lossis 500 yuav tshwm sim nrog kev tswj hwm ib txhij ntawm St. John's wort. Qhov no yog vim qhov txo qis ntawm valproic acid hauv cov ntshav ntshav.
- Cov kev mob tshwm sim ntawm Depakine Chrono 500 lossis 300 yuav tshwm sim thaum cov tshuaj no ua ke nrog lwm cov tshuaj tiv thaiv kab mob vwm uas muaj lamotrigine. Nrog rau kev sib xyaw ua ke ntawm cov tshuaj no, cov tawv nqaij tawv heev (epidermal necrolysis) tuaj yeem ua tau. Nws yog ib qho tsim nyog yuav tsum nco ntsoov tias qhov nce hauv plasma concentration ntawm lamotrigine yog ua tau vim qhov txo qis hauv daim siab metabolism.vim sodium valproate. Yog tias qhov kev sib xyaw ua ke ntawm cov tshuaj no yog tsim nyog, yuav tsum tau ua tib zoo kho thiab soj ntsuam hauv chav kuaj.
- Kev tswj hwm ntawm "Depakine" thiab kev npaj muaj carbamazepine tuaj yeem ua rau txo qis ntawm valproic acid hauv cov neeg mob ntshav plasma. Qhov no yuav yog vim qhov nce hauv hepatic acid metabolism hauv kev ua ntawm carbamazepine. Hauv cov xwm txheej zoo li no, cov neeg mob raug qhia kom saib xyuas hauv tsev kho mob thiab tshuaj xyuas cov tshuaj noj, tshwj xeeb tshaj yog thaum pib kho.
- Cov teebmeem ntawm "Depakine Chronosphere" ua ke nrog cov tshuaj uas muaj carbapenems thiab monobactams tuaj yeem tshwm sim vim qhov txo qis ntawm cov concentration ntawm valproic acid hauv cov ntshav. Hauv cov xwm txheej zoo li no, cov neeg mob raug qhia kom ua raws li tus kws kho mob tuaj koom, tswj xyuas qhov concentration ntawm cov tshuaj hauv cov ntshav plasma thiab, yog tias tsim nyog, kho cov tshuaj valproic acid thaum lub sijhawm kho cov kab mob.
- Thaum noj cov tshuaj uas muaj felbamate nrog Depakine, cov kev mob tshwm sim kuj tshwm sim.
- Ntau zaus hauv cov menyuam yaus muaj cov tsos mob ntawm kev noj tshuaj ntau dhau ntawm phenobarbital lossis primidone vim noj cov tshuaj uas muaj lawv, ib txhij nrog Depakine. Tib lub sijhawm, cov menyuam yaus hauv kaum tsib hnub yuav tsum tau txo qis hauv cov koob tshuaj phenobarbital lossis primidone.
- Nws tsis pom zoo kom noj "Depakine" ib txhij nrog cov tshuaj uas muaj phenytoin, vim muaj cov metabolism hauv siab.
- Muaj feem ntauKev loj hlob ntawm hyperammonemia los yog encephalopathy yog ntaus nqi rau valproic acid thaum ua ke nrog topiramate. Kev tswj xyuas nruj tshaj plaws thiab kev kuaj sim hauv thawj lub hlis ntawm kev kho mob kuj tseem qhia tau tias muaj cov tsos mob ntawm ammonemia.
- "Depakine" nce toxicity ntawm cov tshuaj nrog zidovudine.
Kev sib tham nrog cawv
Kev siv dej cawv ua ke nrog tshuaj yog qhov txaus ntshai heev rau tib neeg kev noj qab haus huv. Ethanol muaj nyob rau hauv cov dej cawv, thaum cuam tshuam nrog valproic acid, txhim kho nws cov nyhuv hepatotoxic. Kev haus dej cawv thaum lub sij hawm kho nrog Depakine nyuaj rau daim siab.
Special conditions
Thaum lub sijhawm kho nrog Depakine, koj yuav tsum ceev faj heev thaum tsav tsheb thiab koom nrog kev ua haujlwm txaus ntshai uas yuav tsum muaj kev saib xyuas siab thiab ceev ntawm tib neeg kev xav.
Analogues
"Depakin" muaj ntau cov analogues:
- "Convulex". Cov tshuaj muaj nyob rau hauv ntau hom (capsules, tov, ntsiav tshuaj).
- "Valparin XP". Cov tshuaj tau pom zoo rau cov menyuam uas hnyav tshaj nees nkaum kilograms.
- "Enkorat". Cov ntsiav tshuaj enteric yog siv rau cov menyuam yaus hnub nyoog tshaj peb xyoos.
- "Konvulsofin". Cov ntsiav tshuaj raug sau rau cov menyuam yaus hnub nyoog 6 xyoo.
Cov ntsiab lus muag thiab khaws cia
Kev yuav khoom "Depakine" hauv lub tsev muag tshuaj yuav tsum tau tso cai (siv tshuaj) los ntawm tus kws kho mob uas tuaj koom. tus nqi nruab nrabntim "Depakina Chrono" 300 tawm ntawm 100 ntsiav tshuaj yog 1148 rubles. Ib pob ntawm "Depakine Chrono" 500 ntawm 30 ntsiav tshuaj (cov ntim no tam sim no muag) raug nqi 530 rubles.
Txhawm rau khaws cov tshuaj, koj yuav tsum nrhiav qhov chaw nyuaj mus txog qhov chaw uas huab cua kub tsis siab tshaj +25 degrees. Lub txee lub neej ntawm cov tshuaj no yog ob xyoos.
Results
Peb tau tshuaj xyuas cov cai rau noj "Depakine Chrono" 300 thiab cov lus qhia rau kev siv "Depakine Chrono" 500. Kev tshuaj xyuas txog cov tshuaj yog sib xyaw heev. Cov neeg mob nco ntsoov tias nws tuaj yeem txhim kho mus ob peb vas, tshem tawm txoj kev xav ntawm kev ntxhov siab thiab kev ntshai, txawm li cas los xij, nws ua rau inhibition ntawm cov tshuaj tiv thaiv thiab lub cev muaj zog, kev nco tsis zoo, thiab txo qis kev txawj ntse. Rau qee tus, cov tshuaj ua rau tsis tsim nyog tantrums, tearfulness, irritability, aggression, uas cuam tshuam rau kev ua hauj lwm thiab kev sib raug zoo nrog lwm tus neeg.
Kev tshuaj xyuas cov kev mob tshwm sim ntawm "Depakine" hauv cov menyuam yaus kuj muaj. Cov niam txiv nco ntsoov tias cov tshuaj ua rau xeev siab thiab ntuav hauv cov menyuam mos, ncua kev tshwm sim. Tsis tas li, cov neeg mob nco ntsoov cov plaub hau poob thaum noj "Depakine", ua tsis tiav ntawm kev coj khaub ncaws, ua kom tawv nqaij ntawm lub ntsej muag.
Txawm li cas los xij, muaj cov neeg mob txaus siab rau kev kho mob nrog cov tshuaj no. Kev mob tshwm sim ntawm "Depakine Chrono" tuaj yeem zam tau los ntawm kev ua raws li cov lus pom zoo ntawm tus kws kho mob uas tuaj koom thiab saib xyuas tas li ntawm lub xeev ntawm cov kabmob hauv nruab nrog cev. Lub active ingredient nyob rau hauv cov khoom siv tshuaj yogSodium valproate yog tshuaj.
Yog li, tshuaj no yog dab tsi - "Depakin"? Cov neeg mob thiab kws kho mob hais li cas txog nws? Cov tshuaj no yog hu ua ib tug zoo heev tshuaj tiv thaiv kab mob vwm. Cov tshuaj muaj nuj nqis rau nws qhov kev ua haujlwm ntev thiab nce ntxiv ntawm cov khoom siv hauv tib neeg lub hlwb. Qhov tsis zoo ntawm cov tshuaj yog qhov tshwm sim tsis tu ncua ntawm cov kev mob tshwm sim.
