Zaj lus yuav hais txog PDE-5 inhibitor tshuaj. Nws yog lub npe hu hais tias vim erectile kawg, kev ua hauj lwm ntawm lwm yam kabmob thiab lub cev tsis cuam tshuam, nws tsis ua mob rau lub noj qab haus huv thiab lub neej ntawm ib tug txiv neej, tab sis xws li ib tug teeb meem ntawm kev sib deev yog heev nyuaj rau perceive los ntawm ib tug psycho-kev xav ntawm view.. Ib tug txiv neej yuav tsum txhawj xeeb txog qhov zoo ntawm erection thiab potency rau yuav luag tag nrho nws cov neeg laus lub neej, txawm tias tsis pom qhov laj thawj rau kev txhawj xeeb.
Tam sim no, muaj ntau cov tshuaj ntuj uas pab tiv thaiv erectile ntshawv siab, thiab muaj zog erection stimulants nrog ua tsis tiav. Qhov zoo tshaj plaws yog PDE-5 inhibitors, los yog phosphodiesterase hom 5, uas muab ib tug txiv neej nrog ib tug 100% erection, tsis hais txog ntawm etiology ntawm tus kab mob thiab nws hnyav.
Dab tsi yog qhov ua rau erectile kawg?
Yog tias ua ntej ntau yam teeb meem puas siab puas ntsws raug suav hais tias yog qhov ua rau erectile kawg, tam sim no qhov kev xav tau hloov pauv. Nws yog tam sim no paub tias qhov ua txhaum cai hauv 80% ntawm cov neeg mob yog cov organic keeb kwm thiab tshwm sim raws li qhov teeb meem ntawm ntau yam kab mob somatic.
Main organic ua: hypogonadism (dyshormonal mob); angiopathy; neuropathy.
Qhov kev nthuav dav ntawm pathology ntawm lub plawv thiab cov hlab ntsha yog siab heev, ntau dua 50% ntawm kev sib deev muaj zog nrog cov kab mob no muaj kev ua haujlwm tsis zoo, tab sis tsis yog txhua tus neeg mob siv PDE-5 inhibitors - ib hom "tus qauv kub "nyob rau hauv kev kho mob ntawm kev ua txhaum ntawm kev sib deev muaj nuj nqi. Vim li cas nws thiaj li? Hmoov tsis zoo, txog tam sim no, cov neeg mob tau ceev faj txog cov tshuaj no, txawm tias qhov tseeb tias lawv cov txiaj ntsig tau raug pov thawj lawm.
Txoj Cai Kev Kho Mob General
Ua ntej xaiv cov ntsiav tshuaj hom 5 phosphodiesterase inhibitors rau kev kho mob ntawm cov kab mob ntawm cov me nyuam, txhua tus txiv neej yuav tsum txiav txim siab txog lub hlwb thiab somatic prerequisites rau xws li mob. Cov hauv qab no tuaj yeem cuam tshuam rau erection:
- muaj nyob rau hauv lub cev ntawm concomitant systemic pathologies;
- siv tshuaj muaj zog;
- kev ua neej (tus cwj pwm phem, ua haujlwm dhau los, noj ntau dhau);
- kev nyuaj siab thiab kev ntxhov siab.
Kev Pabcuam
Yog tias, tom qab tshem tawm cov kev xav tau ua ntej ntawm kev ua haujlwm tsis zookev ua txhaum cai tsis ploj mus, koj tuaj yeem xub siv kev pab los ntawm tus kws kho mob lossis tus kws kho mob hlwb. Ib txoj kev kho kom zoo tuaj yeem yog kev kho cov khoom noj khoom haus, ua si kis las, tso kev quav yeeb quav tshuaj, poob phaus, thiab tshem tawm cov xwm txheej ntxhov siab uas ua rau muaj kev nyuaj siab. Ntawm lwm yam, erection tuaj yeem rov qab los ntawm kev kho cov kab mob hauv qab, xws li hormonal ntshawv siab, ntshav qab zib, thiab lwm yam.
kev kho mob yog dab tsi?
kho mob nrog:
- sublingual thiab qhov ncauj siv cov ntsiav tshuaj;
- txhaj tshuaj rau hauv cov zis lossis lub cev ntawm cov tshuaj vasoactive.
Alpha-1-blocker tshuaj lossis PDE5-hom inhibitors sai ua ntej kev sib deev kuj tseem tuaj yeem pab ua kom muaj zog erection.
Cov lus qhia tshwj xeeb
Nws yuav tsum tau muab sau tseg tias noj cov tshuaj no tsuas yog tom qab sab laj nrog kws kho mob xwb. Nws yuav txiav txim siab npaum li cas rau txhua kis, vim yog siv irrationally, cov tshuaj yuav siv tsis tau lossis ua rau muaj kev phiv.
Tsim nyog siv
Kev siv PDE-5 inhibitors yog qhov tsim nyog, raws li cov pov thawj los ntawm qhov tseeb hauv qab no:
- cov tshuaj no yog thawj kab kho kho;
- kev siv cov nyiaj no txuas ntxiv rau ntau tshaj 30 xyoo;
- rov sim kho dua tshiab tau ua pov thawj lawv cov txiaj ntsig;
- tshuaj siv tau yooj yim;
- hauv kev xyaum los ntawm ntau labtxiv neej tau pom tias muaj kev nyab xeeb.
Qhia siv tshuaj
Phosphodiesterase type 5 inhibitors yog tam sim no feem ntau nrhiav tom qab hauv kev kho mob erectile kawg, uas muaj txiaj ntsig zoo ntawm cov tshuaj pharmacokinetic, muaj txiaj ntsig zoo thiab muaj cov txheeb ze tsis raug mob.
Cov tuam txhab tshuaj tsim cov tshuaj ntau yam uas txhawb nqa erection. PDE-5 inhibitors suav nrog cov tshuaj hauv qab no.
"Sildenafil". Nws kuj yog ib qho kev xaiv PDE5 inhibitor, uas yog thawj zaug tsim nyob rau hauv 1996. Zaj duab xis-coated, yuav luag dawb los yog dawb, puag ncig, biconvex ntsiav tshuaj nrog ib tug yuav luag dawb los yog dawb core nyob rau hauv cross section.
Cov khoom xyaw nquag yog sildenafil nitrate, hauv ib ntsiav tshuaj - 28.09 mg, uas sib haum rau 20 mg ntawm sildenafil. Cov khoom xyaw uas tsis muaj zog: microcrystalline cellulose, anhydrous calcium hydrogen phosphate, croscarmellose sodium, magnesium stearate.
Zaj duab xis muaj talc, hypromellose, titanium dioxide, polyethylene glycol 4000 (macrogol 4000).
Cov ntsiav tshuaj yuav tsum tau noj ib teev ua ntej kev sib deev, qhov kwv yees li niaj hnub noj yog li ntawm 50 txog 100 mg. Cov nyhuv ntawm cov tshuaj yuav kav ntev li plaub teev.
Phosphodiesterase type 5 inhibitor "Vardenafil". Qhov no yog ib qho kev txhim kho thiab tshiab xaiv inhibitor, uas tau lees tias nws siabKev ua tau zoo rau kev sib npaug lom hauv ntau qhov kev tshawb fawb soj ntsuam (raws li monohydrochloride trihydrate).
Cov tshuaj no tau noj ib hnub ib zaug peb caug feeb ua ntej kev sib raug zoo, nws qhov kev ua yuav kav li 4-5 teev. Qhov koob tshuaj txhua hnub yog kwv yees li 10-20 mg ntawm vardenafil.
Tadalafil yog ib qho kev xaiv inhibitor uas tau ua lag luam tsis ntev los no tab sis muaj txiaj ntsig zoo hauv kev rov ua kom erectile kawg. "Tadalafil" yog tam sim no tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, nyob rau hauv uas lub active ingredient muaj nyob rau hauv 2, 5; 5; 20 thiab 40 mg. Raws li lub active ingredient, cov tshuaj "Tadalafil" muaj xws li ib tug tshuaj ntawm tib lub npe. Nyob rau hauv daim ntawv ntawm excipients, qhov kev npaj muaj cov nram qab no Cheebtsam: giproloza; lactose; croscarmellose sodium; microcrystalline cellulose; magnesium stearate; sodium lauryl sulfate; titanium dioxide; triacetin.
Lub hauv paus ntsiab lus ntawm kev nqis tes ua thiab cov qauv yog txawv me ntsis ntawm Sildenafil, nws cov kev xaiv tsawg dua li ntawm thawj cov tshuaj. Qhov ua tau zoo ntawm cov tshuaj muaj pes tsawg leeg kav 36 teev. Cov tshuaj yuav tsum tau noj nyob rau hauv ib tug npaum li ntawm 10-20 mg sai ua ntej intimacy. Tsis tas li ntawd, cov tshuaj no tau tso cai ua ke nrog cawv thiab zaub mov, uas yog qhov txiaj ntsig tsis txaus ntseeg rau cov neeg mob.
Udenafil. Ib tug niaj hnub reversible xaiv inhibitor uas ua rau nws yooj yim rau ib tug txiv neej mus cuag ib tug erection. Cov ntsiav tshuaj yuav tsum tau noj 30-90 feeb ua ntej ua taukev sib deev kev sib deev, thiab nws cov nyhuv yuav nyob twj ywm rau 12 teev. Nws yog ib qho tseem ceeb heev uas yuav tau ua raws li tag nrho cov xwm txheej uas tau teev tseg hauv cov lus qhia, txij li cov tshuaj ntawm hom no muaj contraindications thiab kev phiv.
"Avanafil". Tus neeg sawv cev tom ntej ntawm pab pawg PDE-5 inhibitors, uas tseem txhawb nqa vasodilation thiab tso cai rau cov ntshav ntws mus rau cov kab mob sib kis tau yooj yim dua, muab erection los ntawm 100%. Cov ntsiav tshuaj muaj avanafil ua cov khoom xyaw nquag. Cov tshuaj muaj pes tsawg leeg muaj xws li mannitol, hydroxypropylcellulose, fumaric acid, calcium carbonate, hlau oxide thiab magnesium stearate.
Cov tshuaj yuav tsum tsis txhob noj yog tias muaj kev tsis haum tshuaj rau yam tsawg kawg yog ib qho ntawm cov khoom teev saum toj no. Cov tshuaj kho tau zoo ntawm cov tshuaj yog 80%, cov ntsiav tshuaj yuav tsum tau noj 15-20 feeb ua ntej kev sib deev tom ntej. Qhov kev ua tau zoo ntawm cov tshuaj siv sijhawm rau 6 teev, nws tuaj yeem ua ke nrog cawv thiab zaub mov. Hauv qhov no, qhov nruab nrab ntau npaum li cas yog kwv yees li 100 mg ib hnub.
Yuav ua tau dab tsi?
Nws tsim nyog sau cia tias feem ntau ntawm cov tshuaj no los txhawb kev ua haujlwm erectile tso cai rau vasodilation, cov leeg nqaij so, thiab ua tsaug rau qhov no, nws yuav yooj yim dua kom ua tiav erection.
Ntxiv rau, cov khoom zoo li no tsis pom zoo kom ua ke nrog kev haus dej cawv lossis cov khoom noj rog, vim qhov no yuav ua rau qee qhov txo qhov nqus thiab ua haujlwm ntawm cov tshuaj muaj pes tsawg leeg.
Ua ntej noj ib yam ntawm cov tshuaj erectile-restoring cov npe saum toj no, txhua tus txiv neej yuav tsum sab laj txog qhov kev pom zoo ntawm cov tshuaj inhibitor, vim tias kev noj ntau dhau tuaj yeem ua rau muaj kev phiv loj heev.
Contraindications rau noj PDE-5 inhibitors
Nws paub tias cov tshuaj nrog cov khoom siv hluavtaws nyob rau hauv txhua rooj plaub muaj ib daim ntawv teev npe zoo ntawm contraindications, tuaj yeem ua rau muaj kev phiv ntau. Tib yam tuaj yeem hais rau PDE-5 inhibitors contraindicated hauv cov xwm txheej hauv qab no:
- tus neeg tsis muaj hnub nyoog raug cai;
- hypersensitivity rau cov khoom xyaw;
- sib piv siv cov ntsiav tshuaj uas muaj cov organic nitrates;
- mob thiab pathologies ntawm kev ua haujlwm ntawm lub plawv thiab cov hlab ntsha, uas ua rau muaj kev sib deev ntau dua yog qhov tsis txaus ntseeg;
- noj Doxazosin thiab lwm yam tshuaj erection;
- pom kev tsis pom kev vim yog lub ntsej muag uas tsis yog arterial ischemic optic neuropathy;
- mob raum tsis ua haujlwm thiab siv cov tshuaj tiv thaiv zoo sib xws ntau dua ob zaug hauv ib lub lis piam;
- alabsorption, lactase deficiency lossis lactose intolerance;
- glucose-galactose malabsorption.
Side effects
Qhov kev cuam tshuam loj tshaj plaws ntawm kev siv tsis tsim nyog ntawm hom 5 phosphodiesterase inhibitors yog ntuav, xeev siab, mob taub hau, pom kev cuam tshuam (lub teeb pom kev thiab tsis muaj kev xav),kiv taub hau, rhinitis thiab o ntawm lub qhov ntswg, ua tsis taus pa luv, liab ntawm lub ntsej muag. Nrhiav kev kho mob yog tias cov tsos mob tshwm sim.
Kev sib cuam tshuam ntawm Trazodone thiab phosphodiesterase type 5 inhibitors
Trazodone yog ib qho kev xaiv serotonin reuptake inhibitor, nws tseem thaiv 5-HT2A receptors thiab nruab nrab inhibits serotonin reuptake.
"Trazodone" tuaj yeem siv los ua kev kho mob sib cais, thiab ua ke nrog lwm cov tshuaj kom tshem tawm erectile kawg, suav nrog androgens thiab hom 5 phosphodiesterase inhibitors, uas yog, lawv tau sib xyaw ua ke, lawv cov kev cuam tshuam. yog siv tau.
