Muaj ob lub ntsiab ntawm kev tswj hwm lub cev thiab lub cev hauv tib neeg lub cev: kev xav thiab kev lom zem. Thawj ntawm lawv yog nqa tawm, ua tsaug rau ntau innervation ntawm tag nrho cov hauv nruab nrog cev, qog, cov hlab ntsha thiab musculo-ligamentous apparatus.
Lub tshuab thib ob ua haujlwm vim qhov kev ua haujlwm deb ntawm cov tshuaj hormones, uas lawv tsim nyob rau hauv cov qog endocrine, thiab tom qab ntawd hloov nrog cov hlab ntsha mus rau cov ntaub so ntswg lossis lub cev. Yog li, cov tshuaj hormone testosterone, lub ntsiab androgen, yog tsim nyob rau hauv ib tug me me nyob rau hauv lub adrenal cortex, thiab thaum puberty tshwm sim nyob rau hauv cov tub hluas, nws pib nquag ua nyob rau hauv cov noob qes, ces nws tawm mus rau hauv cov ntshav los ntawm lub excretory ducts. cov qog thiab tom qab ntawd muaj kev cuam tshuam rau lub cev musculoskeletal, thiab tseem ua rau daim siab metabolism. Raws li txoj cai tawm tswv yim, testosterone muaj peev xwm tswj hwm kev tsim tawm ntawm lwm cov tshuaj hormones poj niam txiv neej (ob leeg hauv poj niam thiab hauv txiv neej lub cev).
Testosterone Functions
Testosterone qib hauvtxiv neej, ntawm chav kawm, deb tshaj nws theem ntawm cov poj niam, vim hais tias nyob rau hauv cov txiv neej lub cev nws ua hauj lwm ntau dua: nyob rau hauv lub puberty lub sij hawm nyob rau hauv cov tub hluas, nyob rau hauv nws cov cawv, tsim ntawm lub thiaj li hu ua. Lwm yam kev sib deev yam ntxwv, uas yog: "tawg" ntawm lub suab, nthuav lub xub pwg nyom nyob rau hauv kev sib piv nrog lub plab mog, nce nyob rau hauv cov leeg nqaij thiab compaction ntawm cov pob txha, maturation ntawm gametes nyob rau hauv lub gonads.
Hauv cov txiv neej laus, nws kuj pab tswj kev ua haujlwm ntawm kev sib deev, uas yog, kev sib deev muaj siab, muaj zog thiab ua rau tus cwj pwm ntawm kev sib deev psycho-physiological. Cov tshuaj hormone testosterone kuj tsim nyob rau hauv cov poj niam: nyob rau hauv lub adrenal cortex, zes qe menyuam thiab los ntawm converting estrogens. Nws muaj cov nyhuv inhibitory ntawm kev loj hlob ntawm cov follicles hauv zes qe menyuam thiab tswj kev tsim cov estradiol thiab estrone los ntawm hypothalamic-pituitary-adrenal system. Nrog nws cov hypersecretion ntawm cov poj niam los yog cov khoom siv ntawm cov tshuaj uas muaj cov tshuaj no (ntau cov tshuaj anabolic steroids), cov poj niam tsim masculinization, manifested nyob rau hauv ib tug coarsening ntawm lub suab, nce lub cev plaub hau, nqaij loj hlob thiab aggressive cwj pwm..
Txoj cai ntawm testosterone secretion
Muaj ntau lub tswv yim uas cuam tshuam rau qib testosterone. Nws cov qauv hauv cov txiv neej yog 11-33 nmol / liter, thiab hauv cov poj niam tsuas yog 0.24-2.7. poj niam txiv neej cov tshuaj hormones (SHBG). Txawm li cas los xij, tsuas yog pub dawb xwb(ua 2% ntawm tag nrho) thiab albumin-bound testosterone. Tom qab 30-35 xyoo nyob rau hauv cov txiv neej, cov tshuaj hormone Testosterone, ob qho tib si nws bioavailable thiab tag nrho cov feem, zoo li yuav txo qis ntawm qhov nruab nrab ntawm 2-3% / xyoo, thiab thaum muaj hnub nyoog, theem ntawm active testosterone txo los ntawm 5 zaug (piv rau cov hluas), thiab tag nrho - 2.5 zaug. Raws li qee cov lus ceeb toom, qhov no yog vim tsis tsuas yog maj mam txo qis hauv nws qhov zais cia, tab sis kuj tseem ua rau muaj kev sib txuas ntxiv rau SHBG, vim tias qhov seem bioavailable yog deactivated.
