Galactorrhea yog ib qho txawv txav ntawm cov kua mis, kua mis los yog kua los ntawm lub txiv mis ntawm cov qog mammary, uas tsis provoked los ntawm lactation, cev xeeb tub. Pathology tshwm sim hauv kwv yees li 4% ntawm cov poj niam. Nws yog ib nqi sau cia hais tias nyob rau hauv hais txog 75% ntawm tag nrho cov mob, tus kab mob no tshwm sim nyob rau hauv cov poj niam nulliparous. Cov txiv neej uas txaus siab rau qhov tseeb tias qhov no yog galactorrhea yuav tsum paub tias muaj teeb meem zoo sib xws tshwm sim ntawm cov txiv neej, tab sis tsis tshua muaj.
Signs of disease
Pathology tuaj yeem yog ib leeg lossis ob sab. Cov kua dej secreted muaj cov xim mis nyuj los yog lub teeb milky. Yog tias peb tham txog qhov ntau, ces nws tuaj yeem sib txawv heev, thiab kev tso tawm tshwm sim tas li lossis ib ntus. Lawv kuj tuaj yeem tshwm sim los yog tshwm sim tsuas yog tom qab lub siab ntawm lub txiv mis. Tus lej ICD-10 rau galactorrhea yog O92.6.
Rau cov cim qhia ntawm pathology, uas tuaj yeem xaiv tau thiabfickle, suav nrog cov hauv qab no:
- txiv mis loj tuaj, qhov mob tshwm sim;
- txiv mis tej zaum yuav pib ntxhib thiab o;
- palpation xav tias tsis xis nyob thiab mob me ntsis;
- kab ntawm qhov zais cia tseem nyob ntawm daim ntaub;
- nyob rau hauv thaj tsam ntawm lub txiv mis thiab areolas, liab yog pom, maceration ntawm daim tawv nqaij pib tshwm;
- Txiv neej tsis tshua muaj gyno.
Nws tsim nyog sau cia tias galactorrhea yog, ua ntej ntawm tag nrho cov, muaj paug tawm ntawm lub txiv mis.
Degrees of disease
Vim cov kua dej ntau npaum li cas los ntawm cov txiv mis, cov kws tshaj lij hais tias galactorrhea yog kab mob uas muaj ntau qib.
- 1 degree ntawm galactorrhea - kua tawm tsuas yog thaum palpation. Cov kua mis me me los yog colostrum tuaj yeem tawm.
- 2 degree ntawm galactorrhea - thaum palpation, cov kua tawm tawm hauv daim ntawv ntawm lub dav hlau.
- 3 degree ntawm galactorrhea - kua tawm tas li thiab tib lub sijhawm nws tus kheej.
Kev txhim kho kab mob
Cov kws tshaj lij feem ntau ntseeg tias galactorrhea tsis yog ib qho kab mob ywj pheej, tab sis tsuas yog cov tsos mob ntawm cov kab mob sib txawv ntawm cov qog mammary. Qee zaum qhov no tuaj yeem yog qhov tshwm sim ntawm cov theem pib ntawm qee cov kab mob ncaj qha ntawm cov qog mammary. Piv txwv li, oncology lossis fibroadenomatosis pib tsim. Tsis tas li ntawd, tus mob no yuav qhia tau tias muaj teeb meem nrog keeb kwm hormonal. Nyob rau hauv tas li ntawd, nws yog hais txogsiab ntawm prolactin nyob rau hauv cov poj niam nyob rau hauv cov ntshav, uas ua rau cov tsos ntawm tso tawm ntawm lub txiv mis.
YProlactin Txheej txheem cej luam
Yog tias koj xav paub dab tsi prolactin nyob rau hauv cov poj niam, ces koj yuav tsum paub tias lub ntsiab tseem ceeb uas provokes mis nyuj ntau lawm yog ib tug kiag li los yog txheeb ze nce nyob rau hauv tus nqi ntawm cov tshuaj hormones ntawm cov protein - prolactin. Nws synthesis tshwm sim nrog kev pab los ntawm cov hlwb tshwj xeeb uas nyob rau hauv lub anterior pituitary caj pas. Prolactin tseem cuam tshuam rau kev loj hlob ntawm cov qog mammary, tswj cov kua mis, koom nrog hauv kev loj hlob ntawm cov hauv paus hniav, txhawb ovulation, tswj lub cev luteal nyob rau hauv ib txwm muaj, thiab koom nrog hauv kev tsim cov hlab ntsha tshiab.
Ntau tus neeg txaus siab - dab tsi yog prolactin hauv cov poj niam? Prolactin yog ib qho tshuaj hormones tshwj xeeb uas yog lub luag haujlwm rau ntau cov txheej txheem hauv tib neeg lub cev thiab tuaj yeem tsim tsis tau tsuas yog nyob rau hauv lub caj pas pituitary, tab sis kuj nyob rau hauv lwm yam ntaub so ntswg los yog hlwb hlwb. Cov tshuaj hormones yog tsim nyob rau hauv cov qog mammary, nyob rau hauv lub fetoplacental complex. Thaum raug rau ntau lub hlwb, cov tshuaj hormone no tsis muaj qhov kawg ntawm daim ntawv thov. Hauv qhov no, cov lus teb hormonal ntawm qib ntawm kev tso tawm ntawm prolactin nrog lub caj pas pituitary yog qhov tsis tuaj.
Cov tshuaj hormone no tuaj yeem tswj hwm nws tus kheej hauv cov ntshav ntawm tib neeg, vim tias nws muaj kev cuam tshuam rau hypothalamus, uas inhibits cov synthesis ntawm prolactin. Nyob rau tib lub sijhawm, hypothalamus txuas ncaj qha nrog cov qog pituitary thiab lwm cov qog ntawm cov kab mob neuroendocrine. Prolactin synthesis tuaj yeem cuam tshuam los ntawm ntau yamCov xwm txheej ntxhov siab, lactation, insulin, progesterone, thyroid hormones, estrogens.
Lub zog muaj zog tshaj plaws ntawm lub cev xeeb tub yog qhov muaj zog ntawm cov tshuaj steroids hauv zes qe menyuam, feem ntau yog tshuaj estrogen. Nyob rau tib lub sijhawm, norepinephrine, opioids, serotonin, dopamine muaj kev cuam tshuam rau kev tso tawm ntawm prolactin.
Galactorrhea nyob rau hauv yuav luag txhua kis yog tshwm sim los ntawm ntau dhau prolactin nyob rau hauv cov ntshav. Tsis tas li ntawd, pathology yog suav tias yog qhov tshwm sim ntawm hyperprolactinemia syndrome. Tus mob no muaj nyob hauv kwv yees li 80% ntawm cov neeg mob uas muaj ntau tshaj ntawm prolactin hauv cov ntshav. Nyob rau tib lub sijhawm, muaj kev cuam tshuam hauv kev coj khaub ncaws, kev tsis sib haum xeeb, kev xeeb tub lossis nchuav menyuam.
Nws tsim nyog sau cia tias cov kua tsis tas tso tawm ntawm lub txiv mis vim yog qib prolactin hauv cov ntshav siab. Piv txwv li, cov kua dej yuav raug tso tawm txawm tias cov tshuaj hormones no zoo li qub, lossis nws yuav tsis raug tso tawm thaum nws qib siab. Daim duab kho mob tuaj yeem muaj ntau haiv neeg, uas tej zaum yuav yog vim qhov tshwj xeeb rhiab heev ntawm cellular receptors nyob rau hauv cov ntaub so ntswg ntawm lub cev kawg, uas cuam tshuam los ntawm prolactin.
Vim qhov no, cov kua txiv mis yuav tsum tau soj ntsuam ib txhij nrog rau lwm yam kev kuaj mob. Tsis tas li ntawd, qhov no ib leeg tsis tuaj yeem yog vim li cas thiaj kuaj tau tus mob hyperprolactinemia. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum tau hu rau lub chaw zov me nyuam raws sij hawm.
Ua rau tus kab mob hauv menyuam yaus
Qhov laj thawj tseem ceeb ntawm galactorrhea hauv cov tub ntxhais hluasyog ib qho tsis txaus ntawm cov tshuaj hormones hauv lub cev. Tsis tas li ntawd, qhov tshwm sim no tuaj yeem pom hauv cov menyuam yaus ob peb lub lis piam tom qab yug me nyuam vim qhov nce qib ntawm cov tshuaj hormones uas lub caj pas pituitary tsim. Qhov tshwm sim no hu ua "dab ntxwg nyoog mis", thiab nws maj mam dhau mus, raws li cov tshuaj hormones pib zom thiab tawm hauv lub cev.
Qhov thib ob variant ntawm galactorrhea nyob rau hauv cov me nyuam yog cov tsos ntawm pathology thaum puberty. Feem ntau tshwm sim thaum muaj hnub nyoog 12-16 xyoo. Cov kua dej kuj tseem tso tawm vim qhov tsis txaus ntawm hormonal. Nyob rau tib lub sijhawm, kev tshuaj xyuas ntawm cov ntaub so ntswg ntawm lub mis tsis qhia qhov sib txawv ntawm cov qauv.
Qhov ua rau galactorrhea thaum hluas tuaj yeem yog:
- menyuam yaus noj cov tshuaj uas tuaj yeem ua rau nce qib ntawm prolactin lossis nws cov analogues;
- kev noj zaub mov ntawm tus hluas yuav muaj ntau yam tshuaj uas muaj lactogenic;
- tus qog tuaj yeem tsim nyob rau hauv lub caj pas pituitary, uas provokes ntau zuj zus ntawm prolactin;
- tus qog kuj tuaj yeem tsim hauv hypothalamus, hauv thaj chaw uas nyob ib sab;
- txo qis cov thyroid ua haujlwm;
- Cov txheej txheem pathological pib tsim hauv cov qog adrenal, uas ua rau nce qib ntawm cortisol;
- cov menyuam ntxhais tuaj yeem ua haujlwm tsis zoo ntawm zes qe menyuam;
- nyob rau hauv lub raum muaj cov txheej txheem inflammatory uas provokes kev loj hlob ntawm lub raum tsis ua hauj lwm;
- daim siab pathologies nrog rau daim siab tsis ua haujlwm;
- raug mob, hlawv lossiskev phais tau tshwm sim.
Muaj qee lub sijhawm kws kws kho mob tsis tuaj yeem txiav txim siab qhov laj thawj tiag tiag ntawm kev loj hlob ntawm galactorrhea hauv cov menyuam yaus.
Lwm yam ua rau pathology hauv txiv neej thiab poj niam
Muaj ntau ntau yam uas tuaj yeem ua rau galactorrhea. Cov kws tshaj lij txheeb xyuas ntau qhov laj thawj tseem ceeb ntawm galactorrhea hauv cov txiv neej thiab poj niam. Cov no suav nrog:
- Cov qog nqaij hlav zoo uas tsim nyob rau hauv lub caj pas anterior pituitary. Cov no tuaj yeem yog adenomas, prolactinoma, qog nqaij hlav metastatic, sarcoidosis, histiocytosis. Tau kawg, hauv cov txiv neej, galactorrhea tsis cuam tshuam nrog kev xeeb menyuam.
- Pathological formations uas provoked circulatory disorders, kev loj hlob ntawm ib tug inflammatory txheej txheem. Kev hloov pauv ntawm cov qauv kuj tuaj yeem tshwm sim los ntawm cov qog hauv hypothalamus lossis lwm yam limbic tsim ntawm lub hlwb.
- Galactorrhea tuaj yeem txhim kho vim muaj cov txheej txheem inflammatory hauv qaum qaum lossis hlwb.
- Thoracic paj stimulation tej zaum yuav tshwm sim thaum phais rau ib qho laj thawj los yog lwm qhov.
- Oncology, mastitis, kub hnyiab, kab mob herpes simplex tuaj yeem ua rau pom tus kab mob.
- Siv cov tshuaj tiv thaiv hormonal ntev los yog tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kev nyuaj siab, tshuaj tua kab mob.
Yog tias peb tham txog qhov ua rau galactorrhea hauv cov txiv neej, ces qhov no tuaj yeem yog qhov tsos mob tsis zoo. Feem ntau tshwm sim vim kev loj hlobCov qog nqaij hlav hauv lub caj pas pituitary, nyob rau hauv lub xub ntiag ntawm prolactinoma, qog nyob rau hauv cov qog ntshav, los yog tom qab siv hluav taws xob kho. Tsis tas li ntawd, txiv neej galactorrhea tuaj yeem nrog mob hnyav hauv cov qog mammary, gynecomastia, softening ntawm cov noob qes. Yog tias koj tsis pib kho qhov teeb meem, ces galactorrhea ua rau kev ua txhaum ntawm erectile muaj nuj nqi, kev ntshaw kev sib deev yog txo qis.
Galactorrhea tsis ua phem rau tus txiv neej tsuas yog nws noj qee yam tshuaj lossis rov zoo los ntawm lub sijhawm yoo mov.
Kev kuaj kab mob
Txhua cov kev tshawb fawb soj ntsuam thiab biochemical ntawm Mammology Center yog siv los ntsuas ntsuas. Tsis tas li ntawd, kev kawm txog tus neeg mob lub keeb kwm yav dhau hormonal yog ua tiav, x-ray, echographic kawm nrog ductography ntawm cov qog mammary thiab cov kab mob hauv nruab nrog cev. Sib nqus resonance los yog xam tomography ntawm lub hlwb thiab tus txha caj qaum yog ua tiav. Yuav tsum tau sab laj nrog tus kws kho mob, tus kws kho mob oncologist, kws kho mob endocrinologist, neurosurgeon thiab lwm tus kws kho mob tshwj xeeb. Lawv yuav kuaj cov tshuaj estrogen rau galactorrhea, prolactin ntau ntau, thiab lwm yam.
Kev kho mob
Kev kho tus kab mob no yuav nyob ntawm qhov laj thawj dab tsi ua rau nws txoj kev loj hlob. Yog tias muaj qog, ces koj tsis tuaj yeem ua yam tsis muaj kev phais. Hauv lwm qhov xwm txheej, nws yuav txaus kom muaj txoj hauv kev zoo ntawm kev kho galactorrhea nrog cov tshuaj, uas yuav raug qhia.kom ua tiav hormonal tshuav. Yog tias kev txhim kho ntawm galactorrhea provoked kev siv tshuaj, nws yog ib qho tsim nyog yuav tsum tsis txhob noj lawv, yog tias ua tau, lossis hloov lawv nrog lwm cov tshuaj uas muaj tib lub tswv yim ntawm kev ua, tab sis tib lub sijhawm, kom lawv muaj cov tshuaj sib txawv. muaj pes tsawg leeg.
Yog tias kev txhim kho ntawm galactorrhea yog tshwm sim los ntawm cov khoom siv kho tshuab, kab mob dermatological, kab mob, pathologies ntawm cov kabmob hauv nruab nrog cev, tom qab ntawd koj yuav tsum xub tshem tawm lawv thiab tom qab ntawd pib kho galactorrhea ncaj qha. Yog hais tias tus neeg mob raug kev txom nyem los ntawm ib tug idiopathic daim ntawv ntawm galactorrhea, uas provokes zus tau tej cov ntau ntawm prolactin, ces tus kws kho mob muab tshuaj dopamine receptor agonists. Cov tshuaj xws li Parlodel, Bromocriptine, Levodopa.
Cov tshuaj uas tsis yog tshuaj hormonal "Cyclodinone" kuj muaj cov nyhuv dopaminergic, uas tuaj yeem tau txais los ntawm kev siv cov nroj tsuag tshuaj li dawb huv vitex lossis prutnyak. Lub ntsiab feature ntawm cov nroj tsuag yog tias nws stimulates D2 - dopamine receptors ntawm pituitary lactotrophic hlwb. Vim qhov no, ib qho kev txo qis hauv cov qib siab ntawm prolactin hauv cov ntshav tshwm sim. Functional hyperprolactinemia kuj raug tshem tawm.
Nws tsim nyog sau cia tias cov tshuaj "Cyclodinone" normalizes tus nqi ntawm cov tshuaj hormones kev sib deev, uas muaj txiaj ntsig zoo ntawm kev coj khaub ncaws, qhov tshwm sim ntawm mastalgia, mastodynia txo qis, premenstrual syndrome yuav tsawg dua.
Kev kho mob galactorrhea pej xeemtxhais tau tias
Kev kho tus kab mob nrog kev pab ntawm pej xeem cov kev kho mob suav nrog kev siv cov nroj tsuag tshuaj tshwj xeeb, uas muaj phytohormones uas tuaj yeem txo qis qib ntawm prolactin hauv cov ntshav. Xws li kev kho mob suav nrog infusions rau kev noj cov tshuaj ntsuab ntawm sage, periwinkle. Ib qho infusion ntawm jasmine paj yog siv sab nraud. Cov kua txiv hmab txiv ntoo los ntawm stalks ntawm Robert's geranium tsuas yog siv sab nraud li compresses. Los ntawm nws cov nplooj, ib qho infusion lossis decoction yog ua, uas tuaj yeem noj ntawm qhov ncauj.
Txoj kev zoo tshaj plaws yog "French tincture", uas yog npaj los ntawm cov noob los yog nplooj tshiab ntawm nasturtium, nrog periwinkle, nettle.
Nkauj kho siab rau txiv neej
Cov txiv neej uas muaj kab mob xws li galactorrhea tuaj yeem noj "Adas cag" rau ob lub hlis. Nws hais rau vodka lossis cawv diluted nrog dej.
Kev pab zoo heev los daws cov teeb meem ntawm cov mis nyuj drone. Nws yog noj nyob rau hauv daim ntawv ntshiab ntawm peb grams ob zaug ib hnub twg los yog raws li ib tug tincture, uas yog xam tsis raws li zoo raws li ib tug natural khoom. Drone mis nyuj pab kom nce tus nqi ntawm cov tshuaj hormone testosterone hauv lub cev thiab tib lub sijhawm txo qis kev tsim cov prolactin.
Kev txais nyiaj los ntawm cov tshuaj ib txwm muaj tsuas yog pib tom qab kev sab laj nrog koj tus kws kho mob.
Yog tias koj pom tias cov kua dej tau pib tawm ntawm lub txiv mis ntawm cov qog mammary, koj yuav tsum hu rau tus kws kho mob tam sim ntawd thiab kuaj tag nrho. Qhov no yuav tso caiTsis suav nrog kev loj hlob ntawm pathologies hnyav dua li galactorrhea. Tsis tas li ntawd, tus kws kho mob yuav tuaj yeem txiav txim siab qhov laj thawj ntawm qhov teeb meem no thiab xaiv cov kev kho mob zoo tshaj plaws hauv koj tus kheej. Cov tshuaj niaj hnub tuaj yeem yog ib qho kev pab zoo heev uas yuav tso cai rau koj kom tshem tau cov teeb meem tsis zoo uas ua rau muaj kev tsis xis nyob.
