Polycystic zes qe menyuam syndrome (Stein-Leventhal syndrome) yog ib tug poj niam hormonal mob uas yog lub ntsiab ua rau kev coj khaub ncaws irregularities, anovulation, uas ua rau infertility. Qhov tshwm sim ntawm Stein-Leventhal syndrome yog kwv yees li 3% ntawm tag nrho cov kab mob gynecological ntawm cov poj niam nyob rau theem kawg ntawm kev puberty thiab kev tsim cov me nyuam muaj nuj nqi, thaum pib ntawm kev sib deev lub neej (cov poj niam hnub nyoog 20 txog 30 feem ntau cuam tshuam).
Historical facts
Cov pioneers ntawm Stein-Leventhal Syndrome, uas thawj zaug piav qhia txog tus mob no, yog cov kws tshawb fawb Stein thiab Leventhal xyoo 1935, tom qab uas nws tau txais nws lub npe.
Kev kho thawj zaug thiab tsuas yog kev phais mob radical. Kev tshem tawm ntawm thaj chaw uas muaj cov ntsiab lus siab tshaj plaws ntawm cov hlwv ua rau nws muaj peev xwm ua rau muaj peev xwm rov qab muaj peev xwm (muaj peev xwm fertilize) rau tus poj niam, rov qab pib ovulation thiab muaj peev xwm muaj menyuam. Tab sis qhov kev daws teeb meem zoo li no tsis yog ib txwm ua rau muaj kev vam meej, thiab tseem ua rau muaj kev sib txuam thiab lwm yam teeb meem.
daim duab kho mob
Tus kab mob Stein-Leventhal yog tus cwj pwm los ntawm kev tso zis ntau ntxiv ntawm cov txiv neej thiab poj niam cov tshuaj hormones, kev ua haujlwm ntawm zes qe menyuam, ovulation tsis tu ncua lossis lawv qhov tsis tuaj yeem, hypersecretion ntawm adrenal cortex thiab pancreas. Nws kuj yog tus cwj pwm los ntawm kev coj khaub ncaws tsis xwm yeem thiab tsis muaj menyuam.
Cov poj niam uas muaj tus mob no tsis tuaj yeem xeeb tub vim tsis muaj ovulation. Thiab yog tias lawv ua tiav, kev yug me nyuam yog qhov nyuaj heev rau lawv, muaj kev pheej hmoo loj ntawm kev nchuav menyuam lossis yug ntxov ntxov.
Nrog kev kho kom raug, qhov kev soj ntsuam tau zoo thiab cov poj niam feem ntau muaj peev xwm nqa tau thiab yug me nyuam noj qab haus huv.
Yog vim li cas
Txog thaum kawg, qhov xwm txheej uas ua rau muaj qhov tshwm sim ntawm pathology tsis paub. Muaj ib qho kev hloov pauv hloov pauv, nrog rau cov xwm txheej uas muaj kev pheej hmoo, uas Stein-Leventhal syndrome tuaj yeem txhim kho. Cov laj thawj yuav muaj raws li hauv qab no:
- Genetic predisposition, keeb kwm ntawm tus mob hauv ib tus neeg hauv tsev neeg, cov txheeb ze ntshav. Qhov ua tau ntawm kev sib kis ntawm tus mob los ntawm kev qub txeeg qub teg tsis raug txiav tawm. Feem ntau, cov poj niam uas muaj mob polycystic zes qe menyuam hauv lawv tsev neeg, nrog rau lwm yam mob uas tshwm sim los ntawm pathological o ntawm zes qe menyuam, kev loj hlob ntawm lawv daim nyias nyias, feem ntau mob..
- Kab mob ntawm hypothalamic-pituitary system, piv txwv li, kev ua haujlwm tsis zoo ntawm lub adrenal cortex.
- Fibroma ntawm lub tsev menyuam.
- Mastopathy.
- Kev ua txhaum ntawm cov txheej txheem synthesisestrogen hauv zes qe menyuam.
Indirect ua rau tus mob
Kev ua tsis ncaj uas tuaj yeem ua rau lub zes qe menyuam muaj xws li:
- rog, nce nrawm nrawm;
- mob qog noj ntshav;
- metabolic disorder;
- muaj cov kab mob plawv (stroke, myocardial infarction, kub siab);
- diabetes.
Thaum twg kuv yuav tsum mus ntsib kws kho mob?
Muaj cov cim ceeb toom uas yuav qhia tau tias Stein-Leventhal syndrome. Cov cim qhia no tseem tsis tau hais txog qhov kev kuaj mob zaum kawg, tab sis tsuas yog lub sijhawm mus ntsib kws kho mob kom kuaj xyuas koj tus mob. Cov no suav nrog:
- Txiv neej cov plaub hau (hirsutism) yog thawj qhov cim thiab cov tsos mob uas yuav qhia tau tias muaj kev loj hlob ntawm polycystic zes qe menyuam syndrome.
- kev coj khaub ncaws tsis xwm yeem, los ntshav tsawg dhau.
- Twbmuaj menyuam yaus, tsis muaj peev xwm yuav xeeb tub, tsis muaj peev xwm ua kom tau tus me nyuam hauv plab, menyuam tsis taus.
- Pob txuv, pob txuv, greasiness ntawm daim tawv nqaij, oily tawv taub hau thiab plaub hau.
Cov tsos mob tseem ceeb
Stein-Leventhal syndrome yog tus cwj pwm los ntawm cov tsos mob uas tuaj yeem pom hauv cov poj niam cuam tshuam feem ntau:
- Lub sijhawm tsis txaus, lub voj voog tsis sib xws, tsis muaj ovulation.
- Kev rog rog nrog kev tso rog hauv plab.
- Kev tsim ntawm lub tsev menyuam.
- Alopecia nyob rau hauv lub crown cheeb tsam, lub xub ntiag ntawm lateral bald thaj ua rau thaj thiab nyob rau hauv lub hauv pliaj.
- Loj ntawm zes qe menyuam, qhov pom ntawm ntau cov hlwv ntawm lawv qhov chaw.
- Kev Nyuaj Siab, Action, Tsis Txaus Ntseeg, Kev npau taws, kev nruj.
- nce qib ntawm txiv neej androgen cov tshuaj hormones hauv cov ntshav (testosterone, androstenedione).
- Cov tsos mob zoo ib yam li premenstrual syndrome (o ntawm cov qog mammary o, rub qhov mob hauv plab plab, nquag hloov pauv, o, mob nraub qaum).
- Kev ua tsis taus pa thaum pw tsaug zog (apnea), uas ua rau pw tsaug zog, tsis tsaug zog, nkees.
- mob ntev hauv plab plab tshwm sim los ntawm kev loj hlob ntawm endometrium ntawm zes qe menyuam, rub tej yam kev mob.
- Kev loj hlob thiab thickening ntawm endometrium ntawm lub tsev menyuam vim tsim cov tshuaj estrogen ntau dhau.
- Cov qib globulin txo qis.
- Npaj cov ntshav insulin ntau ntxiv.
Kev hloov pauv hauv qhov tsos
Feem ntau, cov poj niam muaj kev coj ncaj ncees nyuaj rau kev mob siab rau Stein-Leventhal syndrome. Cov tsos mob ntawm tus poj niam tsis hloov mus rau qhov zoo dua, uas ua rau tsis xis nyob, tsis ntseeg tus kheej, kev coj ncaj ncees thiab kev nyuaj siab. Qhov teeb meem tsis kaj siab tshaj plaws yog cov tsos ntawm cov plaub hau uas tus poj niam yuav tsum tsis txhob muaj. Cov duab ntawm cov qog mammary tsis hloov, zoo li lub cev. Cov tsos mob tsis kaj siab tshaj plaws uas ua rau koj lub cev tsis txaus siab yog:
- tso cov rog hauv plab;
- nce oiliness ntawm daim tawv nqaij, pob txuv;
- qhov tshwm sim ntawm stretch marks, striae ntawm lub duav, plab thiab pob tw;
- dubxim me ntsis ntawm daim tawv nqaij;
- seborrhea, nce daim tawv nqaij flaking, dandruff;
- ntshai, txiv neej qauv plaub hau poob;
- me me wrinkles thiab quav ntawm daim tawv nqaij.
Lub zes qe menyuam pathologically nce hauv qhov loj, lawv lub plhaub thickens, ua ntom thiab ci. Ntau tus kab mob follicular tshwm sim ntawm lawv qhov chaw, qhia tau hais tias vascular sclerosis thiab kev loj hlob ntawm cov ntaub so ntswg tau pom.
hirsutism
Cov tsos mob tsis zoo tshaj plaws ntawm Stein-Leventhal syndrome yog hirsutism. Nws yog tus cwj pwm los ntawm qhov pom ntawm cov plaub hau tawv thiab ntev ntawm lub cev ntawm tus poj niam raws li txiv neej hom: nyob rau hauv lub hauv siab cheeb tsam, ntawm lub plab, lub puab tsaig, sab sauv daim di ncauj, puab tsaig, thiab nyob rau sab sauv qaum teb, raws li zoo raws li lub hauv siab. qaum, ncig lub txiv mis.
Kev kho tus mob tsis ua rau kom tshem tawm cov plaub hau ntau dhau. Yuav kom tshem tau ntawm lawv, laser, yees duab thiab electrolysis yog siv, uas yuav tshem tawm tag nrho cov plaub hau ntev. Thiab nrog ntau cov txheej txheem rov ua dua thiab mus ib txhis.
Diagnosis
Tus mob tau kuaj pom yog tias muaj ntau yam cim qhia uas feem ntau cov poj niam muaj kev txhawj xeeb txog Stein-Leventhal syndrome. Cov duab ntawm cov poj niam raug kev txom nyem los ntawm tus kab mob ua pov thawj tias tsis yog txhua tus tau hais hirsutism vim yog kev tsim cov txiv neej cov tshuaj hormones ntau dhau ntawm cov qauv. Yog li ntawd, cov yam ntxwv tseem ceeb suav nrog:
- Kev ua haujlwm ntau dhau thiab tso tawm ntawm txiv neej cov tshuaj hormones (androgens).
- Ntau heev ovulation - oligoovulation. Los yoglawv qhov kev tsis tuaj tag nrho yog anovulation.
- Ultrasound qhia pom cov zes qe menyuam polycystic yog tias tsis muaj lwm yam ua rau muaj cyst tsim.
- Qhov loj ntawm zes qe menyuam ntawm ob sab.
Kev kuaj mob nrog x-rays thiab ultrasound.
ntsuas ntsuas
Hauv cov ntshav muaj qhov txo qis hauv cov tshuaj estrogen, tab sis qhov nce hauv cov tshuaj hormones androgen. Nws kuj ua rau kom lawv tawm hauv cov zis.
txhawm rau kuaj xyuas tus mob no, kev sim tshuaj hormonal tshwj xeeb (chorionic gonadotropin lossis progesterone) raug siv, uas tau tawm hauv cov zis ntau ntxiv, uas qhia tias lawv tsim ntau dhau ntawm zes qe menyuam.
Tseeb kho mob
Lub hauv paus ntsiab lus tseem ceeb hauv kev kho mob yog kom ntseeg tau tias qhov tshwm sim ntawm ovulation nyob rau hauv ib tug poj niam kuaj mob Stein-Leventhal syndrome. Kev kho mob yog lub sij hawm ntev thiab complex, feem ntau yog ua nrog kev pab los ntawm cov tshuaj hormonal.
tshuaj estrogen-muaj cov tshuaj progestogen yog siv ("Ovidon", "Regevidon"). Tsis tas li ntawd, raws li ib feem ntawm txoj kev kho mob, antiandrogens tau siv, uas tshem tawm cov tsos mob ntawm androgenization, txwv cov synthesis ntawm cov tshuaj hormones thiab lawv cov hypersecretion hauv qog..
Kev kho mob ntawm Stein-Leventhal syndrome nrog cov tshuaj pej xeem tuaj yeem ua tau zoo hauv kev ua tiav lub hom phiaj xws li cev xeeb tub. Yeej, siv ntau yam tshuaj ntsuab infusions.
Yog tias qhov txiaj ntsig zoo ntawm cov tshuaj tsis pom nyob hauvrau lub hlis, ces kev phais txoj kev los daws qhov teeb meem yog siv - wedge-shaped resection ntawm zes qe menyuam. Qee zaum, curettage ntawm lub tsev menyuam raug pom zoo. Tsis tas li, cov hau kev no tau pom zoo rau kev loj hlob ntawm cov kab mob endometrium ntau dua 20% tom qab hnub nyoog 30.
Txoj kev niaj hnub thiab sparing tshaj plaws los tiv thaiv kev tsim cov adhesions yog laparoscopy (microresection, electropuncture, laser vaporization).
Tom qab ua haujlwm, cov poj niam raug tso cai saib xyuas kev kho mob thiab kuaj mob. Yog tias tom qab rau lub hlis nws tau pom tias kev kho mob ntawm Stein-Leventhal syndrome tsis pab, cov tshuaj tau muab tshuaj ntxiv. Tom qab kev phais, cov lus teb rau cov tshuaj yog nce, uas tso cai rau koj kom ua tiav cov txiaj ntsig zoo.
Tsis muaj kev tiv thaiv tiv thaiv kev txhim kho ntawm tus mob, vim qhov xwm txheej thiab ua rau nws tshwm sim tsis to taub tag nrho. Txiv neej cov qauv plaub hau tuaj yeem yog thawj zaug hu rau qhov pib ntawm polycystic zes qe menyuam syndrome, yog li ntawm qhov pom me ntsis ntawm kev hloov pauv txawv txawv, koj yuav tsum sab laj nrog tus kws kho mob tshwj xeeb.
Stein-Leventhal syndrome: tshuaj ntsuab kho mob
Kev kho mob nrog pej xeem txoj kev, thiab tshwj xeeb nrog tshuaj ntsuab, yuav tsum tsis muaj teeb meem siv los ua kev kho mob ywj pheej thiab hloov pauv cov txheej txheem ib txwm muaj. Qhov no tsuas yog ib qho ntawm cov khoom siv uas tuaj yeem ua tau zoo tsuas yog nrog kev sib koom ua ke.
Txhawm rau kom muaj kev xeeb tub,Nws yog ib qho tsim nyog yuav tau noj tinctures ntawm cov tshuaj hauv qab no:
- Knotweed ncuav ib tablespoon nrog ib khob ntawm boiling dej. Tom qab infusion (2-3 teev), noj ib nrab khob ua ntej noj mov.
- Adas cag tincture yog npaj raws nraim tib txoj kev, tsuas yog nws yuav tsum tau infused rau ntau tshaj 2 teev, qhwv hauv phuam los yog lwm yam ntaub sov. Noj ib tablespoon ua ntej noj mov 4 zaug ib hnub twg.
- Tincture ntawm tshuaj sage yuav tsum tau brewed tib txoj kev. Nws yuav tsum tau noj peb zaug hauv ib hnub, faib lub khob rau hauv peb koob, tsis pub dhau ib nrab teev ua ntej noj mov.
- Marsh qus rosemary yog brewed nyob rau hauv qhov kev faib ua feem ntawm 1 khob dej rau 1 teaspoon ntawm nyom, infused rau txog 8 teev, tom qab uas nws yog noj ib nrab ib khob ua ntej noj mov ib hnub twg.
- Txhawm rau npaj cov tshuaj ntsuab los ntawm kev sau tshuaj ntsuab, koj yuav xav tau nplooj parsley, motherwort, rosehips, plantain, txiv qaub balm, marigold paj, sage, hlua, strawberry nplooj thiab St. John's wort, 10 grams txhua. Ncuav txhua yam rau hauv ib lub thermos, ncuav boiling dej (250 ml), tawm rau tsis pub tshaj 20 feeb. Tom qab ntawd ncuav rau hauv lwm lub thawv thiab tawm rau ib nrab ib teev. Noj ib nrab khob peb zaug ib hnub ua ntej noj mov.
Txhawm rau ua tiav qhov txiaj ntsig zoo tshaj plaws thaum kho, tus poj niam noj zaub mov yuav tsum suav nrog cov khoom noj hauv qab no uas muaj ntau cov vitamins A, E, C thiab B:
- qej:
- radish;
- celery;
- pistachio txiv hmab txiv ntoo;
- ntsuab dos;
- pob kws;
- grapes.
Qhov tshwm sim thiab kev pheej hmoo
Kev kho tsis txaus tuaj yeem ua rau muaj ntau yam tshwm sim. Vim yog qhov ntau lawm ntawm androgens uas qhia txog Stein-Leventhal syndrome, tus poj niam lub ntsej muag tuaj yeem hloov pauv tau, tab sis cov kab mob loj dua kuj tshwm sim, xws li:
- mob ntshav qab zib mellitus;
- mob qog noj ntshav mis;
- stroke;
- mob plawv;
- mob qog noj ntshav endometrial, hyperplasia.
Mechanisms rau txoj kev loj hlob ntawm pathology tseem tsis tau to taub tag nrho. Tsis ntev los no, cov kws tshawb fawb tau tswj xyuas kom pom cov tshuaj kho tau zoo, thaum yav dhau los tsuas yog kev phais txoj kev kho mob tau siv categorically. Hauv kev xyaum kho mob niaj hnub no, ntau qhov xwm txheej ntawm yuav luag tag nrho rov qab tau raug kaw. Hauv cov poj niam, kev coj khaub ncaws rov pib dua, ovulation tshwm sim, thiab nrog nws lub caij nyoog kom ua tiav cev xeeb tub, ua siab ntev thiab yug tus menyuam noj qab nyob zoo. Koj yuav tsum tsis txhob pib lub xeev, txhua tus poj niam tuaj yeem pab tau. Kev pab zoo npaum li cas yuav yog nyob ntawm tsis yog nyob ntawm tus kheej ntawm tus kab mob xwb, tab sis kuj nyob ntawm nws qhov kev kuaj mob raws sij hawm, kev siv txoj kev kho mob nyuaj.