Kev kuaj lipase yog sau rau cov kab mob plab hnyuv. Cia peb saib ze dua ntawm cov enzyme hu ua "lipase" - nws yog dab tsi? Nws ua haujlwm li cas hauv lub cev, thiab cov kab mob dab tsi ua rau nws qhov kev sib txawv ntawm cov qauv hauv cov txiaj ntsig kev sim qhia?
Lipase yog ib qho enzyme uas tsim los ntawm qee yam kabmob ntawm tib neeg lub cev. Nws dissolves, cais thiab zom cov feem ntau ntawm cov rog, thiab tseem ua ntau yam haujlwm tseem ceeb. Pancreatic lipase yog qhov tseem ceeb tshaj plaws. Nws cov dej num tuaj yeem ntsuas tau thaum cov rog nkag mus rau hauv lub cev.
Cov enzyme "ua haujlwm" ua ke nrog colipase (coenzyme) thiab cov kua tsib acids. Nws yog tsim nyob rau hauv tas li ntawd mus rau lub txiav, los ntawm lub ntsws, plab, hnyuv thiab txawm leukocytes - cov qe ntshav dawb teej tug mus rau lub cev. Tseem muaj ib yam li "lingual lipase". Nws yog dab tsi? Qhov no yog ib qho enzyme uas tsim nyob rau hauv lub qhov ncauj ntawm cov me nyuam mos yug tshiab rau thawj tawg ntawm cov zaub mov, uas yog, rau kev puas tsuaj ntawm leej niam cov kua mis.
YPancreatic lipase
NwsCov ntshav siab ntau dua li lwm hom lipase. Txawm li cas los xij, thaum mob pancreatectomy (tshem tawm ntawm pancreas), ib feem me me ntawm lipase tseem yuav nyob twj ywm vim nws tso tawm los ntawm lwm yam kabmob. Hauv kev kuaj zis, lipase feem ntau tsis tuaj. Tom qab "yug" hauv pancreas, nws nkag mus rau hauv cov hnyuv, qhov twg nws ua nws txoj haujlwm tseem ceeb - nws zom cov rog. Pancreatic lipase plays lub luag haujlwm tseem ceeb. Nws yog rau nws cov ntsiab lus uas lawv pub ntshav, txij li cov kev hloov pauv hauv qhov ntsuas no tuaj yeem pab kuaj mob ntau yam kab mob. Qhov twg, peb yuav xav txog hauv qab no.
Pancreatic lipase - yog dab tsi? Nws yog ib qho enzyme uas tsim los ntawm cov txiav ua "tawg" triglycerides rau hauv glycerol thiab ntau dua fatty acids. Nws feem ntau zom cov nceb twb emulsified nrog cov kua tsib.
Kev ua haujlwm ntawm lipase hauv lub cev
Ntxiv rau qhov kev tawg ntawm cov rog, lipase koom nrog hauv lub zog metabolism, thiab tseem koom nrog hauv kev nqus ntawm polyunsaturated fatty acids thiab txawm tias qee cov vitamins - tshwj xeeb, A, D, E, K.
- Hepatic lipase yog lub luag haujlwm rau kev tswj cov qib plasma lipid. Nws txhawb nqa qhov nqus ntawm chylomicrons thiab cov lipoproteins tsawg ntom ntom.
- Gastric lipase yog lub luag haujlwm rau kev txhawb nqa cov roj tributyrin.
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Lingual lipase.
Lipase test
Kev tshuaj ntsuam rau lipase yog ua tiav hauv ob qhov xwm txheej:
- txhawm rau txheeb xyuas tus mob pancreatitis (mob pancreas).
- txhawm rau ntsuas qhov ua tau zoo ntawm kev kho mob pancreatitis.
Kev kuaj ntshav rau lipase yog suav tias yog cov ntaub ntawv ntau dua rau kev kuaj mob pancreatitis dua li kev txiav txim siab ntawm amylase hauv cov ntshav. Txawm li cas los xij, nyob rau theem tom ntej ntawm tus mob pancreatitis, qib lipase tuaj yeem txo qis. Nrog cov kab mob tsis sib haum xeeb (lub npe hu ua "mumps"), nws qib tseem nyob hauv qhov qub thiab nce ntxiv yog tias tus kab mob cuam tshuam rau cov txiav. Qhov no tseem tuaj yeem ua rau mob raum lossis mob raum, txawm hais tias qhov nce hauv amylase hauv qhov no tau hais ntau dua. Yog li, peb saib cov enzyme hu ua "lipase" - nws yog dab tsi thiab nws ua haujlwm li cas hauv lub cev. Cia peb nyob ntawm kev kuaj ntshav rau lipase.
Yuav ua li cas npaj rau kev tsom xam?
Ntshav yog muab nruj me ntsis rau ntawm lub plab khoob, koj tuaj yeem haus dej ua ntej kuaj. Tom qab noj mov kawg, tsawg kawg 8-12 teev yuav tsum dhau mus. Nws yog qhov zoo dua los ua qhov no ua ntej koj pib noj tshuaj lossis 1-2 lub lis piam tom qab koj tso tseg. Yog tias qhov no ua tsis tau, koj yuav tsum paub txog cov tshuaj twg siv ua ntej pub ntshav.
Hnub ua ntej kuaj ntshav, koj yuav tsum mus noj zaub mov - tsis suav cov rog, kib, ntsim zaub mov, cawv, thiab tsis txhob siv lub cev hnyav. Nws raug nquahu kom pub ntshav ua ntej lwm yam kev kuaj mob - fluorography, radiography - lossis cov txheej txheem kho lub cev.
Norm blood lipase theem
Ib qho taw qhia ntawm ntau yam kab mob yog lipase enzyme, cov qauv ntawm cov neeg laus cov txiv neej thiab cov poj niam yuav luag tib yam. Hauv cov neeg laus, uas yog, cov neeghnub nyoog tshaj 18 xyoo - los ntawm 0 mus rau 190 units. Hauv cov menyuam yaus (hnub nyoog qis dua 17 xyoos), cov ntsiab lus lipase ntawm 0 txog 130 units yog suav tias yog qhov tsim nyog.
nce ntshav lipase qhia li cas?
Dab tsi yog qhov nce qib ntawm enzyme hu ua lipase qhia? Cov qauv ntawm nws cov ntsiab lus qhia tau hais tias txhua yam nyob rau hauv kev txiav txim nrog tus txiav, tab sis yog hais tias tus ntsuas yog siab, qhov no yuav qhia tau hais tias cov kab mob hauv qab no:
- Tus mob pancreatitis lossis exacerbation ntawm tus kab mob ntev.
- biliary colic.
- Ntseeg pathologies ntawm lub gallbladder.
- Kev mob rau tus txiav.
- Kev mob qog nqaij hlav hauv pancreas.
- Kev cuam tshuam ntawm cov kab mob pancreatic (pob zeb lossis caws pliav).
- Intrahepatic cholestasis (thiab txo cov kua tsib ntws mus rau duodenum).
- mob plab hnyuv obstruction.
- plab hnyuv infarction.
- YPeritonitis (mob ntawm peritoneum).
- Perforated plab ulcer.
- Kev ua lub cev tsis huv.
- Hepatic pathology, mob hnyav lossis mob ntev.
- Mumps ("mob"), ua rau muaj kev cuam tshuam rau pancreas.
- Metabolic ntshawv siab, uas feem ntau pom hauv gout, ntshav qab zib, rog.
- Cirrhosis ntawm daim siab.
Thiab qee zaum lipase kuj tseem nce ntxiv nrog kev hloov pauv hauv nruab nrog cev thiab tshuaj noj mus ntev, xws li barbiturates, narcotic analgesics, indomethacin, heparin.
Lipasepancreatic nce nrog kev raug mob ntawm cov pob txha tubular. Txawm li cas los xij, txij li qhov kev sim lipase tsis tuaj yeem muab cov ntaub ntawv tsim nyog txog kev puas tsuaj rau lub cev, qhov ntsuas no tsis suav nrog hauv kev puas tsuaj.
Tab sis nrog kev puas tsuaj rau txiav txiav, kev tshuaj xyuas rau lipase thiab amylase tseem ceeb heev. Lawv ib txhij nce nrog ib theem siab ntawm qhov tseeb qhia tau hais tias ib tug pathological txheej txheem tshwm sim nyob rau hauv lub hlwb ntawm lub caj pas. Thaum lub sij hawm normalization ntawm tus neeg mob tus mob, theem amylase rov qab mus rau qhov qub sai dua li qib lipase.
Ua rau txo qis hauv cov ntshav lipase
Yog tias lipase qis, qhov no qhia txog teeb meem xws li:
- Kev loj hlob ntawm ib qho mob qog noj ntshav tshwj tsis yog mob qog noj ntshav pancreatic.
- Ntau dhau triglycerides, uas tshwm sim nrog kev noj zaub mov tsis raug, tshwj xeeb tshaj yog noj cov rog.
- Kev hloov pauv ntawm tus kab mob pancreatitis mus rau theem ntev.
Lipase hauv enzyme npaj
Peb lub cev tsim cov khoom noj enzymes rau kev zom cov protein, rog thiab carbohydrates (cov tseem ceeb yog amylase, lipase thiab protease). Txawm li cas los xij, yog tias muaj kev txo qis hauv kev tsim cov enzymes (enzymatic deficiency), pancreatitis thiab lwm yam kab mob ntawm cov txiav, cov kws kho mob tau sau cov tshuaj uas muaj cov enzymes ntawm cov tsiaj - lawv nyob hauv lub plhaub, yog li lawv tau tiv thaiv txawm tias los ntawm kev nce acidity ntawm cov kua txiv hmab txiv ntoo.. Mus txog lub duodenum, lawv tau qhib rau hauv nws. Feem ntau, cov enzymes tau muab rau hauv cov kev kawm luv luv, tab sis muaj cov xwm txheej thaum lawv yuav tsum tau noj ntev. ntev kev noj cov enzymestej zaum yuav nrog qee qhov kev txo qis hauv pancreatic muaj nuj nqi, txawm li cas los xij, tom qab txiav cov tshuaj, cov haujlwm ntawm lub cev tau rov qab los. Ntawm cov pancreatic enzymes, "Creon", "Festal", "Mezim", "Pancreazim", "Panzinorm" thiab lwm yam tshuaj feem ntau yog muab, lub ntsiab active ingredient ntawm uas yog pancreatin. Nws muaj protease, lipase, amylase. Qib ntawm lipase hauv ib ntsiav tshuaj yog siab dua li qib ntawm lwm cov enzymes. Qhov no yog vim qhov tseeb tias lipase, piv nrog lwm cov enzymes, yog tsim los ntawm lub cev hauv qhov tsawg tshaj plaws thaum muaj mob. Muab hais tias lipase txo qis hauv lub cev, nws cov ntsiab lus hauv kev npaj yog tsawg kawg yog 10,000 units (U).
Kev npaj cov enzyme feem ntau muaj kev nyab xeeb rau lub cev. Lawv feem ntau ua lub luag haujlwm ntawm kev kho mob nrog tshuaj tua kab mob, nrog rau cov tshuaj ua ntej thiab probiotics, nrog rau cov vitamins thiab lwm yam tshuaj.
