Inhaler "Foster": analogues, cov lus qhia rau kev siv

Cov txheej txheem:

Inhaler "Foster": analogues, cov lus qhia rau kev siv
Inhaler "Foster": analogues, cov lus qhia rau kev siv

Video: Inhaler "Foster": analogues, cov lus qhia rau kev siv

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Anonim

Tus Foster inhaler yog ib qho kev kho mob rau kev kho mob ntawm cov kab mob ua pa, tshwj xeeb tshaj yog mob hawb pob bronchial. Raws li cov lus qhia, cov tshuaj tiv thaiv ob qho tib si hauv qab pathology thiab nws tus kheej cov tsos mob, uas tso cai rau koj kom tau txais txiaj ntsig zoo tshaj plaws los ntawm kev siv. Tsis tas li ntawd, qhov tsim tshwj xeeb ntawm aerosol tso cai rau kev nqus pa kom xa cov tshuaj mus rau lub ntsws nrog cov txiaj ntsig siab tshaj plaws thiab yooj yim.

Aerosol txhawb nqa analogs
Aerosol txhawb nqa analogs

Composition

1 koob tshuaj ntawm no aerosol muaj 100 mcg ntawm cov khoom tseem ceeb beclomethasone dipropionate thiab 6 mcg ntawm formoterol fumarate ua cov khoom xyaw nquag.

Cov tshuaj ntxiv: norflurane, ethanol, hydrochloric acid.

Ib daim foos

Tus Foster inhaler yog tsim los ua ib qho kev nqus pa ntawm 180 thiab 120 koob tshuaj hauv cov kaus poom. Hauv ib pobmuaj ib tug aerosol.

tshuaj muaj txiaj ntsig

txhais tau tias "Foster" muaj cov nyhuv bronchodilatory. Beclomethasone thiab formoterol tam sim no nyob rau hauv nws cov muaj pes tsawg leeg muaj cov txheej txheem sib txawv ntawm kev kho mob thiab muaj kev ua tau zoo ntxiv hauv kev txo qhov zaus ntawm kev mob hawb pob.

Beclomethasone yog ib qho nqus tau glucocorticosteroid uas, hauv cov tshuaj noj, muaj cov tshuaj tiv thaiv kab mob, tshem tawm cov tsos mob ntawm bronchial hawb pob thiab qhov zaus ntawm kev tawm tsam ntawm tus kab mob no. Beclomethasone muaj kev phiv tsawg dua piv rau cov kab mob corticosteroids.

Formoterol yog ib qho kev xaiv β2-adrenergic receptor antagonist, uas nyob rau hauv cov neeg mob uas muaj reversible obstructive respiratory pathologies txhawb kev so ntawm bronchial du nqaij. Cov teebmeem bronchodilator ntawm cov tshuaj no tshwm sim li ntawm 1-3 feeb tom qab nqus pa hauv ib koob thiab kav li 12 teev.

Kev sib xyaw ntawm ob yam tshuaj no piv rau kev kho mob monotherapy muab qhov txo qis hauv qhov hnyav ntawm cov tsos mob hawb pob, muaj txiaj ntsig zoo rau kev ua pa ntawm lub ntsws thiab txo qhov zaus ntawm kev tawm tsam.

analogue ntawm foster
analogue ntawm foster

Cov lus qhia rau kev siv

Cov tshuaj nyob rau hauv daim ntawv ntawm ib qho inhaler "Foster" yog qhia rau kev kho mob tseem ceeb ntawm bronchial hawb pob, uas koom nrog kev siv cov β2-adrenergic agonist ntev thiab ib qho glucocorticoid hauv ib qho.tshuaj ua ke.

npe ntawm contraindications

Hauv cov lus qhia rau kev siv rau Foster inhaler, qee qhov contraindications rau kev siv cov tshuaj no, tshwj xeeb tshaj yog:

  • hypersensitivity rau cov khoom xyaw;
  • hnub nyoog qis dua 12 xyoos.

Cov tshuaj Foster yog siv nrog qee qhov ceev faj hauv cov xwm txheej hauv qab no:

  • Ythyrotoxicosis;
  • pulmonary tuberculosis;
  • kab mob, fungal, kab mob kis ntawm cov kab mob ua pa;
  • pheochromocytoma;
  • hypokalemia ntawm hom tsis tswj hwm;
  • mob ntshav qab zib mellitus;
  • idiopathic hypertrophic subaortic stenosis;
  • aneurysm;
  • arterial hypertension hauv chav kawm hnyav;
  • atrioventricular block (theem 3);
  • mob hnyav ntawm lub plawv thiab cov hlab ntsha, suav nrog lub sijhawm mob myocardial infarction, tachyarrhythmia, decompensated CHF, kab mob plawv, mob QT ntev;
  • pub mis niam, cev xeeb tub.
  • Cov lus qhia rau kev siv analogues
    Cov lus qhia rau kev siv analogues

Side effects

Cov tshuaj tiv thaiv tsis zoo uas feem ntau tshwm sim thaum siv cov tshuaj "Foster" yog vim muaj cov tshuaj xws li beclomethasone thiab formoterol hauv cov tshuaj no. Feem ntau, cov kab mob hauv qab no thiab cov tsos mob tshwm sim:

  • mob taub hau;
  • suab nrov;
  • hnoos;
  • rhinitis;
  • bronchospasm;
  • dysphonia;
  • cim qhia ntawm caj pas khaus;
  • ncua sijhawm QT ntu;
  • hloov pauv hauv ECG;
  • siab lub plawv dhia;
  • muscle cramps;
  • tremor;
  • dry mouth;
  • kub hnyiab hauv daim di ncauj;
  • dysphagia;
  • dyspepsia;
  • mob plab;
  • ua xua dermatitis;
  • nce siab ntawm C-reactive protein;
  • flu;
  • pharyngitis;
  • hypokalemia;
  • gastroenteritis;
  • candidiasis ntawm qhov ncauj mucosa, pharynx thiab esophagus;
  • sinusitis;
  • vaginal candidiasis.

Cov kev mob tshwm sim feem ntau yog mob taub hau, hypokalemia, palpitations, tremors, hnoos, QT prolongation thiab mob leeg.

txhawb nqa inhaler analogues
txhawb nqa inhaler analogues

Ntxiv rau, kev txhim kho ntawm lwm yam, tsis tshua muaj kev phiv tshwm sim tau:

  • thrombocytopenia;
  • angioedema;
  • nce ntshav glycerol, insulin, ketone derivatives thiab fatty acids;
  • hyperglycemia;
  • faus;
  • pw tsis tsaug zog;
  • kev txhim kho ntawm kev hnov lus;
  • hloov saj;
  • xov xwm;
  • ventricular extrasystole;
  • angina;
  • atrial fibrillation;
  • tachyarrhythmia.

Nws puas tuaj yeem noj tshuaj ntau dhau?

Yog tias koj siv cov tshuaj ntau npaum li cas, cov kev mob tshwm sim ntawm formoterol tuaj yeem nce ntxiv. Ib tug neeg tuaj yeem raug kev txom nyem:

  • mob taub hau;
  • nauseous;
  • emeticreflexes;
  • tshiav txhais tes thiab taw;
  • hypokalemia;
  • mob siab;
  • sluggishness, tawg;
  • tachycardia;
  • nce ntshav qabzib ntau.

Thaum cov tsos mob txaus ntshai tshwm sim, yuav tsum tau kho cov tsos mob. Hauv tshwj xeeb yog mob hnyav, kev mus pw hauv tsev kho mob tau sau tseg. Tsis tas li ntawd, nws yuav tsum nruj me ntsis tswj cov qib ntawm cov poov tshuaj hauv cov ntshav.

Kev noj ntau dhau ntawm beclomethasone tuaj yeem ua rau tsis zoo hauv kev ua haujlwm ntawm adrenal cortex. Tus mob no tsis xav tau kev kho tshwj xeeb, nws feem ntau rov qab mus rau qhov qub tom qab ob peb hnub.

txhawb nqa analogues ntawm cov tshuaj
txhawb nqa analogues ntawm cov tshuaj

Tawm tsam keeb kwm yav dhau los ntawm kev siv tshuaj aerosol ntau zaus, pom muaj kev cuam tshuam rau lub cev ntawm cov tshuaj hormones, uas tsis ntev los sis tom qab ntawd yuav ua rau muaj teeb meem sympathoadrenal (panic attack).

Cov lus qhia ua pa nqus pa

Nws yuav tsum nco ntsoov tias Foster tsis yog npaj rau kev kho thawj zaug. Kev xaiv ntawm cov tshuaj inhaler, ob qho tib si thaum pib ntawm kev kho mob thiab thaum lub sijhawm tu, tshwm sim ntawm tus kheej thiab nyob ntawm qhov nyuaj ntawm tus kab mob.

Rau cov neeg laus thiab cov menyuam yaus hnub nyoog qis dua 12 xyoos, 1-2 nqus tau ob zaug hauv ib hnub.

Siv lub tshuab nqus pa

Yuav kom kho tau zoo thiab ua tiav qhov nqus tau zoo tshaj plaws ntawm cov tshuaj hauv lub ntsws, nws yuav tsum kawm cov txheej txheem kom raug rau kev siv lub cuab yeej.

Ua ntej thawj qhov nqus pa lossis tom qab so 3-hnub hauv kev kho mob uas twb tau sau tseg lawm, thawj koob tshuaj yuav tsum tau muab tshuaj tsuag rau hauv huab cua kom kuaj xyuasntaus ntawv xwm txheej. Tuav lub tshuab nqus tsev nrog lub qhov ncauj tawm, tshem lub hau, tso lub qhov ncauj rau hauv koj lub qhov ncauj thiab qhwv koj daim di ncauj nruj nreem. Tom qab exhaling los ntawm lub qhov ntswg, ua pa ntev ntev los ntawm lub qhov ncauj thaum nias lub valve ntawm lub kaus poom. Tom qab cov txheej txheem no, koj yuav tsum tuav koj cov pa thiab tshem tawm cov cuab yeej tawm ntawm koj lub qhov ncauj.

Analogues ntawm "Foster"

Nyob hauv khw muag tshuaj hauv tsev, Foster inhalation tshuaj muaj ntau yam analogues. Cov no suav nrog cov tshuaj ntawm Lavxias thiab txawv teb chaws:

  • Flixotide;
  • Bekotid;
  • "Salbutamol-Teva";
  • "Ingakort";
  • Atrovent.

Flixotide

Cov tshuaj no yog Lavxias teb sab analogue ntawm Foster inhaler. Fluticasone propionate (cov khoom tseem ceeb) belongs rau qeb ntawm cov tshuaj corticosteroids hauv zos thiab, thaum noj inhaled nyob rau hauv cov koob tshuaj kom raug, muaj ib tug pronounced anti-allergic thiab anti-inflammatory nyhuv, uas ua rau ib tug txo nyob rau hauv qhov hnyav ntawm cov tsos mob ntawm tus kab mob. thiab qhov zaus ntawm exacerbations ntawm cov kab mob uas tau nrog los ntawm kev cuam tshuam ntawm cov kwj dej ua pa (bronchial hawb pob, emphysema, mob bronchitis).

Cov lus qhia rau kev siv tshuaj inhaler rau kev siv analogues
Cov lus qhia rau kev siv tshuaj inhaler rau kev siv analogues

Fluticasone propionate zoo inhibits kev loj hlob ntawm mast hlwb, lymphocytes, eosinophils, neutrophils, macrophages, txo cov tsim thiab tso tawm ntawm inflammatory mediators thiab lwm yam biologically active tshuaj: prostaglandins, histamine, cytokines, leukotrienes. Dab tsi lwm cov analogues ntawm "Foster" paub?

Bekotid

Cov tshuaj no yog tsim nyob rau hauv Fabkis thiab yog ib qho nqus tau glucocorticosteroid nrog kev ua haujlwm tiv thaiv. Cov tshuaj no yog tsim nyob rau hauv daim ntawv ntawm ib tug metered-dose inhalation aerosol thiab belongs rau lub pharmacological qeb ntawm GCS. Lub ntsiab tseem ceeb ntawm cov muaj pes tsawg leeg - beclomethasone dipropionate - yog ib tug prodrug nrog ib tug tsis muaj zog tropism rau GCS receptors. Raws li kev cuam tshuam ntawm esterases, nws tau hloov mus rau hauv cov tshuaj nquag metabolic - beclomethasone-17-monopropionate, uas muaj cov nyhuv anti-inflammatory hauv zos. Qhov analogue ntawm cov tshuaj "Foster" no pab txo qhov o ntawm bronchial epithelium thiab txo qis cov qog, txo cov qog nqaij hlav hauv ob sab phlu, thiab muaj cov nyhuv so ntawm cov leeg nqaij.

YSalbutamol-Teva

Cov tshuaj uas ua rau Israeli ua pa nrov tshaj plaws, ib qho analogue ntawm Foster. Lub luag haujlwm tseem ceeb yog salbutamol sulfate, uas txhawb nqa β2-adrenergic receptors. Hauv kev siv tshuaj kho mob, nws ua rau β2-adrenergic receptors ntawm cov leeg nqaij bronchial, muab cov txiaj ntsig tseem ceeb hauv bronchodilator. Cov tshuaj no pab tiv thaiv thiab tshem tawm bronchospasm, ua kom lub ntsws muaj peev xwm. Tsis tas li ntawd, nws tiv thaiv kev zais ntawm histamine, ib qho kev tiv thaiv qeeb ntawm cov hlwb mast, txhawb kev nthuav dav ntawm cov hlab ntsha, thiab xyaum tsis txo cov ntshav siab. Qhov no analogue ntawm Foster inhaler muaj cov nyhuv tocolytic: nws txo cov suab nrov thiab contractility ntawm myometrium thiabNws muaj ntau yam metabolic zog: txo qhov concentration ntawm K + hauv plasma, cuam tshuam cov txheej txheem ntawm glycogenolysis thiab insulin tso tawm, muab cov nyhuv lipolytic thiab hyperglycemic, tab sis ua rau kom muaj acidosis..

Cov lus qhia ntawm inhaler analogues
Cov lus qhia ntawm inhaler analogues

Qhov kev txiav txim ntawm tus neeg sawv cev kho mob pib kwv yees li 5 feeb tom qab kev tswj hwm thiab kav ntev li 6 teev raws li cov lus qhia siv. Analogues ntawm "Foster" yuav tsum tau xaiv los ntawm kws kho mob.

Ingakort

Nov yog ib hom tshuaj German uas tuaj nyob rau hauv daim ntawv ntawm inhaler. Cov tshuaj nquag ntawm cov tshuaj yog flunisolide hemihydrate, uas yog nyob rau hauv qeb ntawm corticosteroids hauv zos thiab, thaum noj inhalation nyob rau hauv cov koob tshuaj kom raug, muaj ib tug pronounced anti-allergic thiab anti-inflammatory nyhuv, uas ua rau ib tug txo nyob rau hauv qhov hnyav ntawm cov tshuaj. Cov tsos mob ntawm tus kab mob thiab qhov zaus ntawm exacerbations ntawm cov kab mob uas muaj nrog obstructive tej yam kev mob ntawm cov pa kwj dej (bronchial hawb pob, emphysema chronic bronchitis).

Fluticasone propionate zoo inhibits kev loj hlob ntawm mast hlwb, lymphocytes, neutrophils, macrophages, txo cov tsim thiab tso tawm inflammatory mediators thiab lwm yam biologically active tshuaj - prostaglandins, histamine, cytokines, leukotrienes.

Cov tshuaj no yog contraindicated nyob rau hauv hypersensitivity, mob bronchospasm, xwm txheej asthmaticus (raws li ib tug tseem ceeb tshuaj), uas tsis yog-asthmatic bronchitis. Qhov no tau lees paub los ntawm cov lus qhia siv rau cov analogue ntawm Foster inhaler.

Atrovent

YBroncholytictus neeg sawv cev uas muaj nyob rau hauv daim ntawv ntawm aerosol. Chaw tsim tshuaj paus - Lub teb chaws Yelemees.

Qhov kev sib piv ntawm "Foster" no thaiv cov M-cholinergic receptors ntawm cov leeg ntawm cov hlab ntsha tracheobronchial thiab suppresses qhov tshwm sim ntawm reflex bronchoconstriction. Muaj cov txheej txheem zoo sib xws rau acetylcholine molecule, nws suav tias yog nws cov antagonist sib tw. Kev tso tawm ntawm calcium ions yog ua nrog kev pab los ntawm cov neeg nruab nrab, suav nrog DAG (diacylglycerol) thiab ITP (inositol triphosphate). Anticholinergics tiv thaiv kev nce qib hauv cov cell ntawm calcium ions, uas tau pom los ntawm kev sib cuam tshuam ntawm acetylcholine thiab muscarinic receptors nyob rau hauv cov leeg ntawm lub bronchi..

Analogous aerosol "Foster" zoo tiv thaiv qhov tshwm sim ntawm bronchospasm uas tshwm sim los ntawm kev nqus cua txias, haus luam yeeb, kev ua ntawm ntau yam tshuaj, thiab tseem ncaj qha tshem tawm bronchospasm los ntawm cov teebmeem ntawm lub paj hlwb. Nrog kev siv inhalation, nws xyaum tsis muaj cov nyhuv resorptive. Lub bronchodilation uas txhim kho tom qab nqus tau cov tshuaj pharmacological no feem ntau yog tshwm sim los ntawm nws cov teebmeem hauv zos thiab cov teebmeem tshwj xeeb ntawm lub ntsws, thiab tsis yog qhov tshwm sim ntawm nws txoj kev cuam tshuam.

Peb tau tshuaj xyuas cov lus qhia thiab cov analogues ntawm Foster inhaler. Kev tshuaj xyuas yuav ua raws.

Reviews

Muaj ntau qhov kev tshuaj xyuas ntawm cov vev xaib kho mob txog ob qho tshuaj Foster thiab nws cov analogues. Ntawm lawv, Lavxias teb sab analogue ntawm cov tshuaj no, Flixotide, tsim nyog saib xyuas tshwj xeeb, uas muaj qis dua.tus nqi ntau dua li lwm txoj kev thiab muaj kev ua haujlwm nrawm. Raws li rau Foster inhaler, cov neeg mob pom tias nws yog ib qho tshuaj zoo heev rau kev tshem tawm kev tawm tsam ntawm bronchial hawb pob thiab nrog rau kev txhim kho ntawm obstructive bronchitis. Nws txo cov tsos mob sai sai thiab tsis tshua muaj tshwm sim.

Pom zoo: