Mob thiab hnyav hauv plab ib ntus tshwm sim hauv yuav luag txhua tus neeg. Qhov no feem ntau tshwm sim tom qab noj cov zaub mov muaj roj, overeating, nrog rau cov kab mob ntawm lub plab zom mov. Lub plab zom mov muaj ntau cov enzymes uas zom cov protein, rog thiab carbohydrates. Tom qab ntawd cov khoom crushed nkag mus rau hauv cov hnyuv. Nyob ntawd lawv tau absorbed thiab faib los ntawm lub circulatory system ntawm lub cev. Qee zaum cov txheej txheem ntawm kev sib cais yog cuam tshuam, thiab cov ntsiab lus tseem ceeb ntawm cov khoom noj ncav cuag cov hnyuv tsis hloov. Qhov no ua rau malabsorption, nrog rau cov kab mob dyspeptic (diarrhea, quav quav). Qee zaum, lub cev tus kheej cov enzymes tsis muaj sijhawm los ua lawv txoj haujlwm hauv qhov xav tau ntim, uas tau hais tawm hauv qhov hnyav ntawm lub plab, mob hauv thaj tsam epigastric, sab xis thiab sab laug hypochondrium. Feem ntau qhov no yog vim tsis noj zaub mov. Hauv cov xwm txheej zoo li no, cov tshuaj "Pancreatin" pab daws qhov tsis xis nyob, cov analogues uas paub ntau.
Mechanism of drug action
Txhim kho cov txheej txheemkev zom zaub mov, nws yog ib qho tsim nyog yuav tsum ua kom tsis muaj enzymes. Cov tshuaj "Pancreatin" ua raws li txoj cai no. Nws muaj ntau yam ntawm porcine thiab bovine pancreatic enzymes uas muaj cov txheej txheem tsim nyog rau tib neeg txoj hnyuv. Cov khoom xyaw tseem ceeb ntawm cov tshuaj:
- Lipase - rau kev zom cov rog.
- Pancreatic amylase - zom zaub mov carbohydrates.
- Proteases, suav nrog chymotrypsin thiab trypsin - cov enzymes no ua rau cov khoom noj protein.
Yog tus kws kho mob tau sau cov tshuaj no, tab sis tam sim no nws tsis muaj, ces koj tuaj yeem hloov cov tshuaj Pancreatin tau yooj yim, cov tshuaj analogues uas muaj nyob hauv txhua lub tsev muag tshuaj. Cov no suav nrog cov tshuaj hauv qab no: Mezim, Pancreasim, Creon, Panzinorm, Festal, Gastenorm forte, thiab lwm yam.
Cov lus qhia rau kev siv
tshuaj npaj cov enzyme yog siv rau kev ua txhaum ntawm pancreatic secretion. Cov ua rau yuav txawv, feem ntau cov no yog cov kab mob ntawm lub plab hnyuv. Cov lus qhia yog: pancreatitis ntawm ntau yam etiologies, suav nrog cawv, cystic fibrosis - kab mob cuam tshuam nrog cov protein metabolism tsis zoo. Tsis tas li ntawd, thaum tshem tawm cov qog, txhawm rau txhawm rau txhawm rau txo cov enzymes, cov tshuaj "Pancreatin" yog siv. Analogues ntawm cov tshuaj yog muab rau tib yam kev ua txhaum cai. Tsis tas li ntawd, cov tshuaj no muaj txiaj ntsig zoo hauv cov kab mob dyspeptic, flatulence, raws plab, cholecystitis,kab mob ntawm cov kua tsib, tsis txaus ntawm cov hnyuv thiab plab thaum lawv raug tshem tawm.
Qhov sib txawv ntawm cov tshuaj analogues "Pancreatin"
Txhua cov tshuaj uas tau teev tseg muaj tib lub hauv paus thiab cov khoom muaj txiaj ntsig - tsiaj pancreatic enzymes. Yog li ntawd, thaum yuav cov nyiaj no, cov neeg mob feem ntau nug cov lus nug: "Pancreatin" lossis "Mezim", uas zoo dua? Vim li cas thiaj muaj tus nqi sib txawv thiab nws puas cuam tshuam rau kev ua haujlwm?
Qhov tseeb, qhov sib txawv ntawm cov analogues me me: lawv muaj nyob rau hauv ntau npaum ntawm cov enzymes tseem ceeb, muaj lossis tsis muaj cov kua tsib thiab hemicellulose hauv kev npaj. Piv txwv li, cov tshuaj "Mezim-forte" muaj 3500 lossis 10000 IU ntawm lipase, thiab tsis muaj cov khoom ntxiv. Nyob rau hauv lem, kev npaj "Festal" kuj muaj cov kua tsib thiab hemicellulose. Yog tias koj xaiv dab tsi zoo dua los yuav cov tshuaj "Creon" lossis "Pancreatin", tom qab ntawd ua tib zoo saib xyuas qhov tsis muaj enzymes, txij li thawj tus muaj cov lipase siab, yog li nws tuaj yeem siv tau me me.
Contraindications rau kev siv tshuaj "Pancreatin" thiab nws cov analogues
Txhua qhov kev npaj enzyme, tsis hais qhov concentration ntawm cov tshuaj nquag, yuav tsum tsis txhob noj los ntawm cov menyuam mos thiab menyuam yaus hnub nyoog qis dua ob xyoos. Qhov no yog vim qhov tseeb tias lawv tseem tsis tau tsim tag nrho cov haujlwm ntawm lub plab zom mov. Tsis tas li ntawd, nrog hypersensitivity rau nqaij npuas thiab nqaij nyuj, plab hnyuv thiab exacerbations ntawm cov kab mob ntev, cov tshuaj yuav tsum tsis txhob siv."Pancreatin". Analogues kuj muaj cov contraindications. Nws yuav tsum nco ntsoov tias cov tshuaj tsuas yog siv rau kev mob ntev ntawm tus txiav. Mob pancreatitis yog ib qho kev txwv tsis pub siv cov tshuaj npaj enzyme, vim tias lawv tuaj yeem ua rau qhov muag tsis pom ntawm tus kab mob thiab ua rau nws qhov kev mob hnyav zuj zus.
Cov teebmeem ntawm cov tshuaj thiab nws cov analogues
Cov tshuaj uas muaj cov enzyme pancreatin tuaj yeem ua rau muaj kev cuam tshuam hauv zej zog thiab dav rau lub cev. Cov teebmeem tshuaj muaj xws li: cov tshuaj tiv thaiv hypersensitivity, cov tsos mob zoo ntawm peritoneal irritation, thiab malabsorption ntawm folic acid. Yog tias koj siv cov tshuaj "Pancreatin" lossis "Mezim", ces tej zaum yuav muaj kev phiv hauv zos, uas yog, cuam tshuam hauv plab hnyuv. Cov no suav nrog: xeev siab, ntuav, raws plab lossis cem quav, tsis xis nyob hauv thaj tsam epigastric. Lub plab hnyuv tuaj yeem tshwm sim thaum kho cystic fibrosis.
Kev sib tham nrog lwm cov tshuaj
Nrog rau kev siv cov tshuaj antacids ib txhij (txo cov acidity ntawm lub plab), cov nyhuv ntawm cov tshuaj "Pancreatin" thiab nws cov analogues tsis muaj zog. Yog hais tias tus neeg mob noj cov hlau los yog folic acid npaj, ces cov tshuaj enzyme yuav pab kom qeeb los yog cuam tshuam lawv txoj kev nqus hauv cov hnyuv.
Cov tshuaj yuav tsum tau siv tom qab kev sab laj nrog koj tus kws kho mob. Cov tshuaj "Pancreatin" tuaj yeem siv rau kev mob plab me me (qhov hnyav tom qabCov zaub mov muaj roj), cov tshuaj analogues ntawm "Creon" thiab "Mezim" raug tshuaj rau cov txheej txheem hnyav dua (cov kab mob ntev, tshem tawm cov txiav tawm).
