TSH, aka thyroid-stimulating hormone, hu ua regulating. Nws yog tsim nyob rau hauv lub caj pas nyob rau hauv lub hlwb, uas yog lub caj pas pituitary, thiab ncaj qha cuam tshuam rau kev tsim ntawm ob lwm yam tshuaj hormones: T3 thiab T4. Tom qab ntawd, nyob rau hauv lem, tswj cov metabolism, tshwj xeeb tshaj yog cov metabolism hauv cov proteins thiab vitamin A.
Kev piav qhia ntawm cov thyroid stimulating hormone
Thyrotropic hormone yog tsim nyob rau hauv anterior ib feem ntawm lub caj pas pituitary. Nws cuam tshuam nrog triiodothyronine (T3) thiab thyroxine (T4), thiab lawv, dhau los, cuam tshuam rau kev ua haujlwm ntawm cov thyroid-stimulating hormone los ntawm lub qog pituitary. Ntawd yog, thyroid-stimulating hormone provokes zus tau tej cov thyroxine thiab triiodothyronine, thiab thaum lub sij hawm tom kawg yuav txaus rau lub cev, lawv muab ib lub teeb liab rau lub hlwb kom nres los yog txo cov thyroid-stimulating hormone.
TSH. Yog vim li cas
Ua rau dhia hauv TSH cov kab mob, feem ntau cuam tshuam nrog kev hloov pauv hauv cov thyroid caj pas thiab pituitary caj pas, nrog rau qee yam tshuaj lom, tshem tawm cov kabmob. Tej yam ua tau ntawm hyperthyroidism suav nrog:
uatshuaj lom;
kab mob thyroid;
kab mob oncological;
resection ntawm lub hauv nruab nrog cev;
kab mob sib kis;
nce qib ntawm iodine hauv lub cev;
ncua toxicosis hauv cov poj niam cev xeeb tub;
Hashimoto's thyroiditis;
ua tsis zoo ntawm cov tshuaj hormones los ntawm lub cev;
kab mob qog adrenal
Cov thyroid-stimulating hormone ntau hauv lub cev hu ua hyperthyroidism. Nws kuj tshwm sim tias qee yam tuaj yeem cuam tshuam cov txiaj ntsig tiag. Piv txwv li, cov ntsiab lus ntawm TSH raug cuam tshuam los ntawm kev ua lub cev. Cov thyroid-stimulating hormone nce thaum tus neeg noj ntau cov tshuaj. Tus nqi ntawm qhov tshwm sim tiag tiag tsuas yog txiav txim siab tom qab tso tseg cov tshuaj.
Symptoms
Ua ntej tshaj, TSH ntau dhau tsis tau txhais tias yog kab mob. Tus mob no tsuas yog qhia txog teeb meem tshwm sim lossis qhov txawv txav hauv lub cev vim muaj ib yam kab mob. Qib siab ntawm cov thyroid-stimulating hormone nyob rau hauv lub cev yog nrog los ntawm:
chim siab;
lub cev qaug zog;
insomnia;
tsis tau piav qhia thiab qhov hnyav nce sai;
tawv nqaij daj;
lub cev kub poob;
txo qis qhov concentration;
o tshwm sim hauv ntau qhov chaw ntawm lub cev;
teeb meem nrog kev ua haujlwm ntawm plab hnyuv;
poob qab los
Cov tsos mob zoo li no yog ib qho zoo rau cov neeg uas muaj qhov tsis txaus ntawm cov tshuaj hormones thyroxine, triiodothyronine thiab thyroid-stimulating hormone. Yog ibob peb ntawm cov tsos mob no tshwm sim, koj yuav tsum xeem dhau qhov kev xeem tsim nyog. Tej zaum qhov laj thawj yog qhov tseeb qhov txo qis hauv qib ntawm cov tshuaj hormones saum toj no. Lwm cov tsos mob tuaj yeem raug ntxiv rau cov tsos mob piav qhia:
txo libido (libido);
nce siab loj;
npaj tsis tiav ntawm kev coj khaub ncaws;
kab mob tawv nqaij thiab plaub hau poob;
hypotension;
teeb meem nco;
mob leeg;
zoo li tsis muaj menyuam
Diagnosis
Thaum cov tsos mob tshwm sim uas yog tus yam ntxwv ntawm tus mob thaum TSH nce siab, muaj laj thawj los sab laj tus kws kho mob thiab kuaj xyuas qib TSH. Nws yuav tsum tau nco ntsoov hais tias lub hnub nyoog ntawm tus neeg thiab lub sij hawm thaum lub sij hawm soj ntsuam tau ua tiav yog ib qho tseem ceeb heev nyob rau hauv dab tsi qhov tshwm sim ntawm lub TSH theem yuav yog. Thaum tsaus ntuj, ib tug neeg lub TSH theem siab, qhov no yog vim lub fact tias tag nrho cov plab hnyuv siab raum slows down thaum hmo ntuj. Cov thyroid caj pas kuj qeeb nws txoj haujlwm. Raws li ib tug neeg lub hnub nyoog, yuav muaj qhov sib txawv me ntsis ntawm cov thyroid-stimulating hormone theem rau cov neeg laus thiab cov me nyuam.
Rau cov menyuam yaus, cov tsos mob hauv qab no tuaj yeem ua qhov laj thawj rau kev mus ntsib kws kho mob endocrinologist thiab kuaj cov thyroid-stimulating hormone: qaug zog, tsis txaus ntseeg, txias ntawm tes thiab taw, qaug zog. Hauv cov menyuam yaus, TSH tuaj yeem nce siab vim yog cov kab mob ntawm cov qog adrenal, nrog rau vim muaj kev cuam tshuam los ntawm kev cuam tshuam, thaum tus me nyuam muaj cov neeg uas raug kev txom nyem los ntawm hyperthyroidism hauv tsev neeg.
Yog tias ib tus neeg muaj qib ntawm cov thyroid-stimulating hormone siab dua li cov qauv, kev kuaj ntxiv raug muab rauelucidate qhov ua rau ntawm tus mob no. Kev tsom xam yog ua thaum sawv ntxov, thiab ntshav tawm ntawm cov leeg.
Kev sib raug zoo ntawm cov kab mob thyroid thiab nce qib ntawm cov thyroid-stimulating hormone
Raws li twb tau hais lawm, muaj kev sib raug zoo ntawm kev tso tawm cov thyroid hormones triiodothyronine (T3) thiab thyroxine (T4) thiab cov thyroid-stimulating hormone (TSH). Thaum muaj qhov txo qis ntawm T3 thiab T4, tom qab ntawd tsis muaj dab tsi los tswj cov qib ntawm cov thyroid-stimulating hormone hauv cov ntshav, thiab nws qhov nce ntxiv. Nyob rau hauv lem, cov thyroid caj pas tsis yog cia li tso tseg tsis tsim cov tshuaj hormones, raws li ib tug tshwm sim ntawm lub xeev tau pom thaum TSH nce. Raws li txoj cai, qhov no tshwm sim vim nws ntau yam kev hloov pauv pathological thiab kab mob, nrog rau lwm yam. Nov yog qee qhov ntawm lawv:
nce qib ntawm prolactin hauv lub cev (hyperprolactinemia);
tshem tawm ntawm cov thyroid caj pas (ib yam mob uas tau pom vim qhov kev txiav tawm ntawm lub caj pas no, nws hu ua postoperative hypothyroidism hauv tus mob no)
TSH hormone elevated, if present:
tshuaj lom iodine;
postpartum thyroiditis
Puas muaj lwm yam laj thawj? Kev nce TSH hauv cov poj niam yog qhov tshwm sim ntawm:
mob iodine deficiency;
autoimmune thyroiditis;
ntau lub cev mob (kev ntxhov siab, pw tsaug zog, kev ntxhov siab thiab kev tawm dag zog lub cev hnyav);
laus;
radiotherapy
Cov Me Nyuam Tshiab kuj muaj qib siabcov thyroid-stimulating hormone.
nce TSH hauv cov poj niam thiab txiv neej yog tshwm sim los ntawm kev noj qee yam tshuaj - Cerucal, Eglonil, Amiodarone thiab cov tshuaj hormonal uas muaj estrogen.
YTyrotropic cov tshuaj hormones
Raws li tau hais los saum toj no, nce TSH qib thaum lub sij hawm cev xeeb tub yog suav tias yog qhov qub. Nyob rau hauv txoj cai, qhov no yog lub xeev uas ib txwm theem ntawm thyroid-stimulating hormone yuav siab tshaj. Nyob rau hauv lub neej yav tom ntej, raws li ib tug neeg loj hlob, qhov taw qhia no yuav txo qis thiab ruaj khov. TSH nce los yog txo tuaj yeem ua rau lub sijhawm sib txawv ntawm hnub. Raws li txoj cai, thaum hmo ntuj, uas yog nyob ib ncig ntawm ob thaum sawv ntxov, theem ntawm cov thyroid-stimulating hormone yog siab tshaj, thiab nws cov nqi qis tshaj yog sau tseg ntawm tsib los yog rau yav tsaus ntuj.
Vim li ntawd, cov menyuam mos yuav muaj lub xeev ib txwm muaj thaum TSH nce siab, thaum cov qauv hauv cov neeg laus yuav txawv me ntsis:
- hauv cov menyuam yug tshiab, qhov no yog qib 1 txog 17;
- menyuam yaus hnub nyoog qis dua peb lub hlis 0.5 txog 11;
- ntawm peb lub hlis mus rau ib xyoos tus qauv yuav yog los ntawm 0.5 txog 7;
- ntawm peb mus rau tsib xyoos tus qauv yog 0.5-6;
- hauv cov menyuam yaus hnub nyoog 5 txog 15 xyoos, tus qauv yuav yog los ntawm 0.5 txog 5;
- rau cov uas twb muaj 15 xyoos lawm, ib theem ntawm 0.5 mus rau 4 yuav suav hais tias yog tus qauv.
Nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account cov ntsiab lus hauv qab no kom cov ntaub ntawv ntawm cov tshuaj hormones hauv kev tsom xam tsis txawv txav - qhov no yog kev pub ntshav thaum sawv ntxov, ib txwm nyob ntawm lub plab khoob. Ua ntej kuaj, piv txwv li ib hnub lossis ob hnub ua ntej, nws yog qhov zoo dua tsis txhob haus cawv lossis haus luam yeebrau qhov tseeb ntsuas ntawm cov tshuaj hormones hauv cov ntshav.
Treatment for elevated TSH
Yog li peb tau kawm cov tsos mob tshwj xeeb thaum TSH qib siab. Qhov no txhais tau li cas tau piav qhia saum toj no. Thiab hom tshuaj twg yog siv rau kev kho mob ntawm ib qho mob? Ua ntej ntawm tag nrho cov, nws tsis tsim nyog, txawm tias nruj me ntsis txwv tsis pub, mus rau tus kheej-medicate thiab nws tus kheej sau tshuaj thiab hom tshuaj. Qhov no yuav tsum tau ua los ntawm kws kho mob, vim tias thaum xub thawj tus neeg mob cov ntshav yuav muaj qhov sib txawv ntawm cov thyroid-stimulating hormone thiab thyroxin. Raws li qhov piv txwv no, tus kws kho mob xaiv hom tshuaj, nws cov koob tshuaj thiab lub sijhawm kho.
Nws tseem tsis tau pom zoo kom siv ntau yam tshuaj ntsuab raws li kev kho mob tseem ceeb, uas yog, cov tshuaj siv tshuaj. Lawv muaj txiaj ntsig zoo, tab sis rau cov kab mob loj thiab cov tshuaj hormones tsis txaus, nws yog qhov zoo dua los siv cov tshuaj tshwj xeeb. Ntxiv mus, yog tias koj tsis quav ntsej txog kev kho mob ntawm qib siab ntawm cov thyroid-stimulating hormone hauv lub cev, ces cov qog nqaij hlav qog nqaij hlav tuaj yeem tsim tawm tsam keeb kwm yav dhau los. Yog li hauv qee kis, thaum mob qog noj ntshav tshwm sim, TSH nce siab hauv ib tus neeg, raws li txoj cai.
Nyob rau hauv kev kho mob ntawm kev nce siab ntawm cov thyroid-stimulating hormone nyob rau hauv lub cev, ib tug synthetically derived npaj uas muaj cov tshuaj hormone thyroxine (T4) yog siv. Ib zaug ib zaug, tib neeg siv qhuav thiab av tsiaj cov thyroid caj pas hauv kev kho mob. Tam sim no thawj qhov kev xaiv yog qhov zoo tshaj plaws, vim yog purity ntawm cov khoom nquag. Kev kho mob txuas ntxiv mus txog thaum qhov sib piv ntawm cov tshuaj hormones hauv cov ntshav - TSH,T3 thiab T4, piv txwv li thyrotropic, triiodothyronine thiab thyroxine, feem, yuav tsis zoo li qub. Yuav kom ua tau li no, tus neeg mob yuav tsum tau kuaj xyuas thiab kuaj tsis tu ncua thaum lawv kho.
Tom qab txoj kev kho no, thaum cov tshuaj hormones tau zoo rov qab los, tus neeg mob yuav tsum tau sim txhua xyoo rau cov thyroid-stimulating hormone theem txij li lub sijhawm tawm mus kom tsis txhob rov qab los.
theem ntawm cov thyroid-stimulating hormone thaum cev xeeb tub thiab nws cov kev hloov
Nyob rau lub sijhawm no, kev hloov pauv ntawm tus nqi ntawm qib ntawm cov thyroid-stimulating hormone zoo li. Lawv tuaj yeem hloov pauv lossis nyob ruaj khov, tab sis feem ntau cov ntsiab lus ntawm TSH yuav yog kwv yees li ntawm 0.3 mus rau 3 units. ib litre. Nws yuav zoo li tias nyob rau hauv cov poj niam cev xeeb tub, cov thyroid-stimulating hormone yuav tsum tau qis, vim hais tias nyob rau hauv lub sij hawm no feem ntau ntawm cov poj niam lub cev yog activated thiab lawv ua hauj lwm nyob rau hauv ib tug txhim khu kev qha hom, nrog rau cov endocrine system, uas muaj xws li cov thyroid caj pas. Nws nquag tsim iodine rau lub cev ntawm tus poj niam thiab nws fetus.
TSH nce siab - qhov no txhais li cas rau cov poj niam? Thaum cev xeeb tub, ib qho tshuaj hormone tshwj xeeb yog tsim nyob rau hauv lub cev ntawm tus poj niam, nws yog hu ua "hormone ntawm cov poj niam cev xeeb tub". Nws lub npe kho mob yog tib neeg chorionic gonadotropin (hCG). Nws kuj tseem txhawb kev tsim cov tshuaj hormones thyroxine thiab triiodothyronine hauv lub cev, uas yog cov thyroid-stimulating hormone yuav tsum ua hauv lub xeev qub. Raws li, nws qib qis thaum cev xeeb tub.
Yog TSH nce siab thaum cev xeeb tub, qhov no tuaj yeem ua qhov kev hu xovtooj loj mus rauendocrinologist txhawm rau txheeb xyuas qhov ua rau. Cov mob no tsis yog ib feem ntawm qhov qub, thiab nws tuaj yeem hem tus poj niam fetus.
Meaning of elevated TSH level
Paub txog kev sib raug zoo ntawm cov tshuaj hormones, peb tuaj yeem kos qee qhov kev txiav txim siab los ntawm cov txiaj ntsig ntawm kev soj ntsuam ntawm qib ntawm cov thyroid-stimulating hormone. Rov qab mus rau lub ntsiab lus dua, yog tias tsis muaj nws tsis tuaj yeem nkag siab tias yog vim li cas rau qhov nce hauv cov thyroid-stimulating hormone, peb nco ntsoov tias nrog tsis muaj iodine, cov thyroid caj pas xa cov teeb liab mus rau pituitary caj pas. Nws, nyob rau hauv cov lus teb rau lub teeb liab, pib tsim thiab tso tawm ntau TSH, uas, nyob rau hauv lem, yuav cuam tshuam rau cov thyroid caj pas, yuam nws los tsim ob cov tshuaj hormones - thyroxine thiab triiodothyronine. Cov tom kawg yog xav tau rau kev nqus ntawm iodine hauv lub cev. Ntawd yog, los ntawm qhov no nws tau txiav txim siab tias qib TSH nce ntxiv qhia peb txog qhov tsis muaj iodine hauv lub cev tam sim no.
Actions for elevated TSH
Ua ntej tshaj, koj yuav tsum tau hu rau tus kws kho mob endocrinologist. Txhua txoj kev kho neeg pej xeem, tshuaj ntsuab tsis zoo li muaj cov tshuaj hormones T3 thiab T4 tsim nyog rau tus neeg hauv qhov no. Yog li, feem ntau tus kws kho mob tuaj yeem sau cov tshuaj hauv qab no:
- "Eutiroks";
- "Bagotirox";
- "L-thyroxine".
YDecreased TSH
Nyob rau hauv lub xeev uas ib tug neeg muaj qhov txo qis ntawm cov thyroid-stimulating hormone hauv kev kuaj ntshav, muaj qee yam tsos mob uas tuaj yeem qhia rau tus kws kho mob ua ntej txog kev kuaj mob ntawm tus neeg mob. Nws yog qaug zoglethargy, tsis kub kam rau siab, edema, nco tsis tau, kub siab, kub taub hau. Nyob rau hauv lem, qis TSH theem tuaj yeem ua rau:
- neoplasms (cov qog) ntawm cov thyroid caj pas;
- goiter;
- mob qog nqaij hlav pituitary;
- poob rau hauv pituitary muaj nuj nqi;
- hloov pauv ntawm cov tshuaj hormones vim noj tshuaj muaj cov tshuaj hormones.
Npaj rau kev xeem
Tam sim ua ntej pub ntshav rau kev txheeb xyuas cov ntsiab lus ntawm cov thyroid-stimulating hormone, koj yuav tsum tsis txhob noj. Lub sijhawm ntawm qhov kev tshuaj xyuas yuav tsum tau ua yuav tsum yog thaum sawv ntxov. Ib hnub lossis ob hnub ua ntej qhov kev xeem, nws txwv tsis pub haus cawv thiab haus luam yeeb.
Qhov chaw rau kev sim txhawm rau txheeb xyuas qib ntawm TSH
Xa mus rau kev pub ntshav rau kev tshuaj xyuas cov thyroid-stimulating hormone yuav tsum tau muab los ntawm tus kws kho mob endocrinologist. Nws yog ua nyob rau hauv ib qho ntawm cov chaw kho mob pej xeem. Koj tseem tuaj yeem siv cov khoom ntiag tug, qhov twg lawv muab cov kev ntsuam xyuas sai dua, txawm tias yog tus nqi. Txawm li cas los xij, cov txheej txheem no tsis kim dhau, piv rau pes tsawg lub sijhawm koj txuag los ntawm kev tsis sawv hauv kab.
