Qhov twg analogue ntawm "Riboxin" xaiv: cov lus qhia thiab tshuaj xyuas

Cov txheej txheem:

Qhov twg analogue ntawm "Riboxin" xaiv: cov lus qhia thiab tshuaj xyuas
Qhov twg analogue ntawm "Riboxin" xaiv: cov lus qhia thiab tshuaj xyuas

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Anonim

tshuaj Anabolic yog ib pawg ntawm cov tshuaj uas nws lub luag haujlwm tseem ceeb ntawm kev ua haujlwm yog txhawm rau nce lub zog ntawm cov hlwb, ua kom lawv txoj kev loj hlob thiab kev sib txawv, nce lub cev hnyav thiab ua kom cov txheej txheem metabolic. Ib tus neeg sawv cev ntawm pawg tshuaj no yog Riboxin.

Analogue ntawm riboxin
Analogue ntawm riboxin

tshuaj yam ntxwv ntawm cov tshuaj

Cov tshuaj "Riboxin" yog ib qho tshuaj anabolic, cov txiaj ntsig tseem ceeb uas yog tsom rau kev ua kom cov ntaub so ntswg ua rau hypoxia. Raws li ib tug precursor ntawm adenosine triphosphoric acid, "Riboxin" yog muab kev koom tes nyob rau hauv kev puas tsuaj ntawm qabzib nyob rau hauv lub cell thiab, raws li, tsim ntawm adenosine triphosphoric acid, uas yog lub ntsiab cellular zog substrate. Raws li cov txiaj ntsig no, "Riboxin" muaj cov nyhuv antihypoxic hauv cov xwm txheej ntawm cov ntsiab lus ATP txo.

Cov nyhuv anabolic ntawm "Riboxin" yog tshwm sim los ntawm kev nce hauv cov txheej txheem metabolic uas cuam tshuam nrogpyruvic acid thiab xanthine dehydrogenase activation. Vim muaj cov teebmeem zoo li no, "Riboxin" muaj cov txiaj ntsig zoo ntawm kev ntws ntawm cov metabolism hauv cov cell, pab txhawb lawv lub zog rau kev ua haujlwm zoo.

Thaum raug rau myocardium, "Riboxin" ua kom zoo rau kev ua haujlwm ntawm myocardiocytes, pab txhawb rau lawv cov kev so kom txaus (nce phosphorylation ntawm actin-myosin bonds), thiab tseem ua rau cov txheej txheem rov ua dua tshiab hauv myocardium.

Riboxin cov lus qhia rau kev siv analogues
Riboxin cov lus qhia rau kev siv analogues

Los ntawm qhov pom ntawm cov txheej txheem pharmacokinetic, "Riboxin" zoo kawg nkaus nkag mus rau hauv cov kab ke uas twb muaj lawm hauv lumen ntawm txoj hnyuv. Nrog rau txoj kev parenteral ntawm kev tswj hwm (intravenously), "Riboxin" yog sai sai faib thoob plaws hauv cov ntaub so ntswg nrog rau cov theem tom ntej ntawm cov metabolism hauv lub siab hlwb, qhov twg nws yog kiag li cleaved. Kev tshem tawm ntawm cov metabolites thiab cov tshuaj uas tsis yog metabolized ntawm cov tshuaj tshwm sim hauv cov zis, thiab ib feem me me tau tawm hauv cov quav thiab cov kua tsib.

Cov lus qhia rau kev siv

Cov tshuaj "Riboxin" yog qhia nyob rau hauv txoj kev kho mob ntawm cov kab mob plawv, nrog rau kev kho mob tom qab mob plawv. Cov tshuaj muaj cov txiaj ntsig zoo hauv kev kho mob ntawm atherosclerosis thiab kev cuam tshuam ntawm kev ua haujlwm, kev noj ntau dhau ntawm kev npaj plawv glycoside, kev kho mob ntawm cov leeg mob plawv uas tshwm sim tawm tsam keeb kwm yav dhau los ntawm kev ua kom lub cev muaj zog lossis tom qab kis kab mob thiab mob.

"Riboxin" yog qhia hauv kev kho mobhepatobiliary system, rau kev tiv thaiv ntawm cov kab mob ntawm cov ntshav system thaum tau txais koob tshuaj ionizing hluav taws xob ntau. Hauv kev xyaum ua qhov muag pom kev, kev siv "Riboxin" yog qhov pom zoo rau qhov qhib-qhov glaucoma.

"Riboxin": cov lus qhia rau kev siv, analogues

Thaum siv cov ntsiav tshuaj daim ntawv ntawm cov tshuaj, koj yuav tsum ua raws li cov lus qhia no. Rau cov neeg laus, qhov koob tshuaj txhua hnub ntawm cov tshuaj tuaj yeem yog los ntawm 0.6 txog 2.4 grams. Raws li txoj cai, cov koob tshuaj raug xaiv ib tus zuj zus, thiab cov koob tshuaj txhua hnub tau muab faib ua ob peb koob tshuaj thaum nruab hnub. Cov ntsiav tshuaj daim ntawv yuav tsum tau muab los ntawm qhov tsawg kawg nkaus npaum li cas, thiab tsuas yog yog hais tias qhov tsawg kawg nkaus koob yog ib txwm zam los ntawm tus neeg mob, tom qab 2-3 hnub nws yog nce. Lub sijhawm kho yuav tsum nyob nruab nrab ntawm 1 thiab 3 lub hlis.

analogue ntawm riboxin rau intramuscular txhaj
analogue ntawm riboxin rau intramuscular txhaj

Thaum noj parenterally, 2% kev daws ntawm "Riboxin" yog diluted nrog 250 ml ntawm cov tshuaj physiological ntawm sodium chloride lossis qabzib. Infusion yog nqa tawm maj mam, ntawm tus nqi ntawm 40-60 tee ib feeb.

Nrog cov analogues zoo sib xws thiab cov qauv ntawm daim ntawv thov, nws yog ib qho tsim nyog yuav tsum nco ntsoov "Inosine" thiab "Ribozine", uas yuav tau tham hauv qab no.

Contraindications rau sau tshuaj

Contraindications rau lub sij hawm teem yog hypersensitivity rau ib los yog ntau yam ntawm cov tshuaj, gout thiab siab uric acid nyob rau hauv cov ntshav plasma. Nrog kev ceev faj heev, nws yog ib qho tsim nyog yuav tsum tau sau ntawv "Riboxin" thiab cov analogue ntawm "Riboxin" "Inosine" rau cov neeg mob uas tsis txaus ntawm excretory muaj nuj nqi.lub raum.

Side effects

Cov tshuaj feem ntau zam tau zoo. Ntawm cov neeg uas tau sau tseg hypersensitivity rau cov tshuaj, tej zaum yuav muaj tshwm sim ntawm kev tsis haum tshuaj ntawm daim tawv nqaij. Los ntawm ib sab ntawm cov hlab plawv, tej zaum yuav muaj kev xav ntawm palpitations, nce ntshav siab, tsis muaj zog.

Yog tias tus neeg mob noj "Riboxin" ntsib cov kev mob tshwm sim saum toj no, nws yuav tsum tau sab laj nrog koj tus kws kho mob thiab tsis txhob noj tshuaj.

riboxin analogues hauv cov ntsiav tshuaj
riboxin analogues hauv cov ntsiav tshuaj

Cov Lus Qhia Tshwj Xeeb Nkag

Vim qhov tseeb tias "Riboxin" thiab nws cov metabolites tau tawm ntawm lub cev feem ntau los ntawm ob lub raum, nws tsis pom zoo kom sau cov tshuaj thaum lub raum tsis ua haujlwm. Kev siv cov khoom siv tshuaj no tsuas yog tsim nyog yog tias qhov kev cia siab tau txais txiaj ntsig los ntawm cov tshuaj ntau dua qhov kev pheej hmoo ntawm kev siv nws. Ib txoj cai zoo sib xws yuav tsum tau ua raws li thaum muab tshuaj rau cov poj niam cev xeeb tub thiab lactating.

Muab cov txiaj ntsig ntawm "Riboxin" ntawm qib ntawm uric acid hauv cov ntshav plasma, nws raug nquahu kom saib xyuas nws thaum lub sijhawm kho kom tsis txhob muaj qhov tshwm sim ntawm hyperuricemia.

riboxin analogues ntawm ib tiam tshiab
riboxin analogues ntawm ib tiam tshiab

Tshuaj lom thiab tshuaj ntau dhau

Nyob rau hauv rooj plaub ntawm kev noj cov tshuaj ntau, kev ntsuas dav dav yog coj los txo cov dej ntws ntawm cov tshuaj mus rau hauv cov hlab ntsha. Nyob rau hauv cov ntaub ntawv ntawm cov tsos mob ntawm lom -kev kho mob. Thaum muaj kev ua xua tshwm sim, desensitizing txoj kev kho tau zoo.

"Riboxin": analogues

Hnub no, muaj ntau dua ib qho analogue ntawm "Riboxin" nrog rau hom anabolic ntawm kev ua lag luam tshuaj. Nyob rau tib lub sij hawm, muaj ob qho tib si analogues nrog cov ntsiab lus ntawm lwm yam active tshuaj, thiab tag nrho cov ntsiab lus ntawm cov tshuaj, uas muaj ib tug zoo xws li cov active ingredient nyob rau hauv lawv muaj pes tsawg leeg.

Riboxin cov lus qhia rau kev siv analogues
Riboxin cov lus qhia rau kev siv analogues

"Inosine" tuaj yeem yog cov lus sib dhos thiab cov lus piv txwv ntawm "Riboxin" rau kev txhaj tshuaj intramuscular. Ntawm nws lub hauv paus, cov tshuaj yog ib qho kev hloov pauv rau "Riboxin" nrog tag nrho nws cov indications thiab contraindications. Lwm lub ntsiab lus ntawm cov tshuaj hauv nqe lus nug yog "Ribonosin". Cov tshuaj no kuj muaj nyob rau hauv nws cov muaj pes tsawg leeg ib yam khoom zoo ib yam li cov tshuaj "Riboxin". Ib qho analogue rau cov menyuam yaus hauv syrup yog cov tshuaj xws li Mildronate. Nws kuj muaj peev xwm muab lub zog homeostasis rau txhua lub cev hlwb.

Yog tias peb xav txog cov pab pawg ntawm cov tshuaj uas tsis yog tshuaj steroidal anabolic, peb tuaj yeem paub qhov txawv ntawm cov analogues ntawm "Riboxin" hauv cov ntsiav tshuaj xws li "Methyluracil" thiab potassium orotate. Cov tshuaj no, txawm hais tias lawv koom nrog ntau pawg kws tshuaj, muaj peev xwm ua kom muaj zog anabolic. Qhov tseeb, qhov txiaj ntsig no yuav yog vim kev txhawb nqa ntawm cov txheej txheem metabolic hauv txhua lub hlwb thiab cov ntaub so ntswg ntawm lub cev.

Piv cov tiam tshiab analogues nrog Riboxin, peb nco ntsoov tias lawv muaj ntau duakev ua tau zoo thiab kho cov teebmeem. Tus neeg sawv cev tsim nyog ntawm pab pawg no yog Cytoflavin. Qhov no analogue ntawm "Riboxin" ntxiv rau cytoprotective thiab antioxidant teebmeem muaj ib tug pronounced stimulating nyhuv ntawm lub hlwb neurons.

Analogue ntawm riboxin
Analogue ntawm riboxin

Zoo kawg

tshuaj Anabolic yog ib pab pawg ntau ntawm cov tshuaj uas muaj ntau yam tshuaj. Nyob ntawm lub hom phiaj uas lawv npaj yuav siv, koj tuaj yeem xaiv "Riboxin", analogues ntawm cov tshuaj, lossis them nyiaj ntau dua rau pawg steroid. Nco ntsoov tias kev tswj tus kheej ntawm cov tshuaj no tsis pom zoo. Tsuas yog ib tus kws tshaj lij tshwj xeeb tuaj yeem pab xaiv cov tshuaj.

Pom zoo: