Nyob hauv peb lub ntiaj teb niaj hnub no, yuav luag txhua tus muaj tus cwj pwm phem. Ib tug ntawm lawv yog kev haus luam yeeb, uas tsis yooj yim kom tshem tau. Tab sis vim qhov tseeb tias cov tshuaj tsis nyob twj ywm, niaj hnub no muaj ntau txoj kev los pab koj tsis nco qab txog kev haus luam yeeb. Tab sis qhov tseeb, txhawm rau kov yeej tus cwj pwm phem mus ib txhis, qee qhov "cov tshuaj khawv koob" tsis txaus. Koj kuj yuav tsum muaj lub siab nyiam, thiab tom qab ntawd txhua yam yuav ua tiav.
Champix yog ib yam tshuaj siv los tiv thaiv kev quav tshuaj nicotine. Nws muaj qhov ua tau zoo tshaj plaws ntawm lub sijhawm thaum tus neeg tsis kam lees tus cwj pwm phem. Champix pab ua kom cov txheej txheem no yooj yim dua. Cov tshuaj no, raws li lub hauv paus ntsiab lus ntawm kev ua, ua raws li agonist thiab antagonist ntawm receptors. Nws cuam tshuam nrog lawv thiab neutralizes dopamine activation. Qhov system no yog lub luag haujlwm rau kev lom zem ntawm kev haus luam yeeb thiab kev quav tshuaj. Hauv kev tshuaj xyuas no, peb yuav saib cov ntsiav tshuaj Champix, cov kev mob tshwm sim thiab tshuaj xyuas txog lawv.
Composition
Hnub no hauv cov khw muag tshuaj koj tuaj yeem pom cov tshuaj "Champix" hauv daim ntawv ntawm cov ntsiav tshuaj-coated zaj duab xis. Lub ntsiab active ingredientyog varenicline. Nws muaj nyob rau hauv ob koob tshuaj, 1 mg thiab 0.5 mg. Cov tshuaj ntxiv tuaj yeem muab faib ua ob pawg: cov uas tsim cov yeeb yaj kiab thiab cov uas tsim cov ntsiav tshuaj nws tus kheej. Rau ob qho tshuaj, cov ntsiav tshuaj-forming excipients yog tib yam. Tab sis qhov muaj pes tsawg leeg ntawm lub plhaub yuav txawv.
Cov tshuaj muaj pes tsawg leeg ntawm cov ntsiav tshuaj nws tus kheej 1 thiab 0.5 mg suav nrog cov tshuaj xws li:
- calcium hydrogen phosphate;
- croscarmellose sodium;
- colloidal silicon dioxide;
- Ymicrocrystalline cellulose;
- Ymagnesium stearate.
Cov tshuaj ntawm lub plhaub ntawm cov ntsiav tshuaj 0.5 mg suav nrog Opadry dawb thiab Opadry pob tshab, thiab cov tshuaj 1 mg - Opadry pob tshab thiab Opadry xiav.
Cov tshuaj 0.5mg yog dawb thiab convex nyob rau hauv cov duab. Ntawm ib sab muaj cov ntawv sau Pfizer, thiab nyob rau lwm qhov - CHX 0.5. Cov ntsiav tshuaj dawb nrog ntau npaum li 0.5 mg feem ntau muaj nyob rau hauv 11 lossis 56 ntsiav tshuaj. Ntawm kev muag khoom kuj tseem muaj cov ntsiav tshuaj xiav nrog rau ntau npaum li 1 mg. Pfizer luam tawm ntawm ib sab thiab CHX 1.0 ntawm lwm qhov. Nws tuaj yeem muaj 56, 28 lossis 14 daim hauv ib pob. Kuj tseem muaj cov pob khoom uas muaj cov ntsiav tshuaj nrog ob qhov ntau npaum li cas. Feem ntau cov phiaj no muaj 14 xiav thiab 11 ntsiav tshuaj dawb.
Pharmacological action
Cov txiaj ntsig ntawm Champix cov tshuaj haus luam yeeb yog dab tsi? Kev tshuaj xyuas cov neeg mob paub tseeb tias cov tshuaj no zoo heev. Cov tshuaj nquag ntawm cov ntsiav tshuaj tuaj yeem cuam tshuam nrog α4β2 n-cholinergic receptors ntawm lub hlwb, uas yog ib feem ntawm nicotine agonist. Qhov teeb meem yog cov hlwblimbic system muaj nicotinic receptors. Thaum cuam tshuam nrog lawv, kev tsim cov tshuaj dopamine yog nqa tawm. Ib tug neeg pib muaj kev zoo siab los ntawm cov txheej txheem ntawm kev haus luam yeeb. Dopamine nws tus kheej yog hu ua hormone ntawm kev zoo siab. Cov tshuaj no yog tsim los ntawm lub hlwb hlwb thiab piav qhia txog kev xyiv fab los ntawm txhua qhov kev ua. Nov yog qhov ua rau muaj kev quav yeeb quav tshuaj.
Hauv lwm lo lus, yog tias muaj cov txheej txheem uas ua rau tsim cov dopamine los ntawm cov hlwb hlwb, lub cev pib txaus siab. Thaum nicotine los ntawm luam yeeb nkag mus rau hauv lub hlwb, nws cuam tshuam nrog nicotinic receptors. Lub hlwb nquag pib tsim dopamine. Raws li qhov tshwm sim, tus neeg xav tau kev txaus siab. Maj mam, koj tuaj yeem ua rau haus luam yeeb. "Champix", tshuaj xyuas uas feem ntau zoo, thaiv lub peev xwm ntawm nicotine los txhawb α4β2 n-cholinergic receptors. Vim li no, tus neeg siv tshuaj txo qhov kev lom zem ntawm luam yeeb. Nws kuj tseem pab txhawb txoj kev tshem tawm cov tsos mob, tshuaj "Champix". Kev mob tshwm sim, kev tshuaj xyuas tus neeg mob, thiab contraindications yuav tau tham hauv qab no.
Champix qhov kev ua haujlwm siab tau ntev tau ua pov thawj. LEEJ TWG tau lees paub cov tshuaj hauv nqe lus nug yog ib qho cuab yeej zoo tshaj plaws rau cov neeg uas xav txiav luam yeeb. Raws li kev tshawb fawb tshawb fawb, ob lub lis piam ntawm kev siv cov ntsiav tshuaj yog txaus los tiv thaiv kev quav tshuaj ntawm koj tus kheej. Nws yog vim li no uas Champix tau txais kev tshuaj xyuas zoo los ntawm cov neeg haus luam yeeb. Yog tias nyob rau hauv ob peb lub lis piam nws tsis tuaj yeem txiav qhov kev quav yeeb quav tshuaj, koj tuaj yeem ua tausim noj cov tshuaj rau kev kawm 5-lub lim tiam. Nyob rau lub sijhawm no, tus neeg mob yuav tuaj yeem xaiv nws tus kheej xaiv hnub zoo rau kev txiav luam yeeb.
Kev qhia
Cov kws kho mob qhia txog kev haus cov ntsiav tshuaj Champix, kev tshuaj xyuas uas tau nthuav tawm hauv qhov kawg ntawm tsab xov xwm, tsuas yog siv rau kev kho mob nicotine rau cov neeg laus. Cov tshuaj yuav tsum tsuas yog siv yog tias tus neeg sim txiav luam yeeb. Kev noj cov tshuaj hauv nqe lus nug yuav pab ua kom tawg tus cwj pwm yooj yim dua thiab ua tau zoo dua.
Kev qhia
Ua ntej siv, koj yuav tsum paub koj tus kheej nrog nws. Yog li, cov lus qhia rau kev siv Champix hais li cas? Kev tshuaj xyuas ntawm cov neeg haus luam yeeb tau lees paub tias tsis muaj dab tsi nyuaj hauv kev kho kev quav tshuaj nrog cov tshuaj no. Nws yog txaus kom nqos cov ntsiav tshuaj tag nrho, tsis muaj crushing. Koj tuaj yeem sim zom cov tshuaj thiab siv lwm txoj hauv kev. Koj yuav tsum noj cov tshuaj nrog ib khob dej. Koj tuaj yeem siv "Champix" txhua lub sijhawm ntawm hnub. Sim soj ntsuam kwv yees li ntawm qhov sib npaug ntawm lub sijhawm ntawm cov tshuaj rov ua dua.
Yuav ua li cas haus cov tshuaj "Champix" los tiv thaiv kev quav tshuaj nicotine? Cov lus qhia rau kev siv thiab tshuaj xyuas cov kws kho mob tso cai rau peb muab ob peb cov lus pom zoo. Ua ntej, qhov ua tau zoo ntawm kev kho mob zoo nyob ntawm qhov loj npaum li cas tus neeg xav txiav luam yeeb. Yog tias koj tsis xav tso tseg qhov kev tiv thaiv no, feem ntau yuav ua rau Champix txheej txheem yuav tsis ua haujlwm zoo. Nws yog qhov zoo tshaj plaws los pib noj cov tshuaj li ntawm ob lub lis piam ua ntej koj yuav tsum tau txiav tawm hnub.
PibChampix zoo dua li hauv qab no:
- txij thawj hnub mus rau peb hnub haus ib zaug ntawm 0.5 mg;
- txij hnub plaub mus rau hnub xya, noj 0.5 mg ntsiav tshuaj ob zaug;
- pib txij hnub yim mus txog rau thaum kawg ntawm chav kawm, cov tshuaj yog qaug cawv ntawm ib koob tshuaj 1 mg ob zaug ib hnub.
Yog tias tus neeg mob tsis kam ua siab ntev rau Champix, ces qhov koob tshuaj tuaj yeem txo qis li ib nrab. Nyob rau hauv tag nrho, lub sijhawm ntawm chav kawm tuaj yeem yog los ntawm 12 txog 24 lub lis piam. Nyob rau hauv thawj rooj plaub, txoj kev kho yog xam luv luv, thiab nyob rau hauv lub thib ob - ntev. Lub sijhawm luv luv suav nrog kev noj tshuaj ntawm cov tshuaj saum toj no rau 12 lub lis piam. Tib lub sijhawm, koj tuaj yeem tsis kam haus luam yeeb pib txij hnub yim ntawm kev siv Champix. Kev tshuaj xyuas ntawm cov neeg uas tau tso tseg kev quav yeeb quav tshuaj paub meej tias lub sijhawm no yog qhov zoo tshaj plaws. Koj tseem tuaj yeem tso luam yeeb rau ib hnub twg los ntawm yim mus rau 35th. Yog tias tsis pub dhau 12 lub lis piam nws tsis tuaj yeem tshem tus cwj pwm, ces nws raug nquahu kom haus cov tshuaj ntxiv rau 84 hnub. Nws yog qhov zoo tshaj plaws los noj 1mg ntsiav tshuaj ob zaug ib hnub. Cov kev kho zoo li no yuav pab txhawb kev tsis lees paub. Cov hnub nkag ntxiv tsis suav nrog hauv chav kawm uas xav tau.
Kev kho mob ntev (24 lub lis piam) tsuas yog xav tau yog tias tus neeg tsis tuaj yeem txiav luam yeeb ntawm lawv tus kheej. Hauv qhov xwm txheej no, nws tsim nyog pib haus cov tshuaj raws li cov txheej txheem saum toj no. Nrog rau qhov no, nws yog ib qho tseem ceeb kom txo tau cov luam yeeb. Thaum kawg ntawm lub lim tiam 12, ib tug neeg tsis haus luam yeeb kiag li. CesCov tshuaj yuav tsum tau qaug cawv rau 84 hnub ntxiv ntawm 1 mg ib hnub.
Vim li ntawd, tag nrho lub sijhawm ntawm chav kawm nrog qhov txo qis ntawm cov neeg haus luam yeeb yog kwv yees li 24 lub lis piam. Yog tias tus neeg mob xav txiav luam yeeb tiag tiag thiab muaj kev txhawb siab txaus kom ua tiav lub hom phiaj no, tab sis tib lub sijhawm nws tsis ua tiav hauv ib chav kawm ntawm kev kho mob nrog Champix thiab rov tshwm sim tom qab ua tiav kev kho mob, cov kws tshaj lij pom zoo kom rov ua cov chav kawm dua.. Txhawm rau ua kom tiav, koj tuaj yeem xaiv ib qho kev xaiv rau kev noj tshuaj - luv (84 hnub) lossis ntev (168 hnub).
Siv rau mob raum
Cov neeg mob uas muaj ntau yam kab mob thiab pathologies tuaj yeem ntsib cov teebmeem sib txawv ntawm Champix. Kev tshuaj xyuas tau lees paub tias qhov ntau npaum li cas ntawm cov tshuaj tuaj yeem hloov kho nyob ntawm cov kab mob ntev thiab pathologies ntawm tus neeg haus luam yeeb. Nws raug txiav txim los ntawm cov qib creatinine. Yog tias nws qhov kev tshem tawm, txiav txim siab los ntawm kev ntsuas Rehberg, ntau dua 30 ml / min, tom qab ntawd cov tshuaj tuaj yeem noj hauv cov koob tshuaj ib txwm muaj. Hauv qhov no, nws muaj peev xwm xaiv tau txhua yam kev kho mob. Yog hais tias ib tug neeg raug kev txom nyem los ntawm cov kab mob raum thiab muaj creatinine tshem tawm tsawg dua 30 ml / min, ua rau tsis zoo rau cov kev mob tshwm sim ntawm Champix, nws raug nquahu kom haus cov tshuaj ib hnub ib zaug ntawm koob tshuaj 1 mg.
Yog tias mob raum hnyav, cov tshuaj yuav tsum tau noj raws li cov txheej txheem hauv qab no:
- ntawm 1st mus rau 3rd hnub - 0.5 mg ib hnub ib zaug;
- ntawm 4th mus rau 7th hnub - 0.5 mg ob zaug ib hnub;
- txij hnub 8 mus txog thaum kawg ntawm kev kho mob - 1 mg ib hnub ib zaug.
Kev siv tshuaj kho mob siab
Thaum lub siab tsis ua haujlwm, Champix tau noj raws li cov txheej txheem ib txwm muaj, ob qho tib si rau lub sijhawm luv thiab ntev. Cov neeg laus raug qhia kom noj cov ntsiav tshuaj ntawm tus qauv noj tsis tau txo qis. Kev txo qis rau 1 mg ib hnub yog tso cai tsuas yog thaum peb tham txog cov neeg mob uas muaj hnub nyoog lossis muaj kab mob siab uas tsis ua rau muaj kev phiv.
Kev txais tos nta
Puas muaj lus pom zoo rau kev kho mob? Cov kws kho mob cov lus pom zoo tias tawm tsam keeb kwm yav dhau los ntawm kev tawm tsam kev haus luam yeeb, nws yuav tsim nyog los kho cov koob tshuaj insulin, "Warfarin", "Theophylline"..
Tus kws kho mob yuav tsum ceeb toom rau cov neeg mob uas siv cov tshuaj tiv thaiv kev haus luam yeeb ntawm qhov muaj peev xwm tsim cov tsos mob neuropsychiatric thiab xav txog qhov yuav tsum tau txo cov koob tshuaj maj mam.
Siv thaum nqa me nyuam
Raws li rau lub sijhawm thaum tus poj niam nqa tus menyuam hauv qab nws lub siab thiab pub niam mis, qhov no "Champix" yog contraindicated rau kev siv. Tsis muaj kev tshawb fawb lees paub qhov kev nyab xeeb ntawm kev noj tshuaj rau tus menyuam tau ua. Nws tseem tsis tau paub yog tias cov khoom xyaw nquag ntawm Champix nkag mus rau hauv cov kua mis.
Side effects
Kev tshawb fawb nrog Champix tau nthuav tawm cov xwm txheej ntawm ntau yam txawv txav hauv cov kab mob neuropsychiatric, xws li tus cwj pwm tsis sib haum, kev xav ntawm kev ntxhov siab, xav qeeb, hloov pauv hauvmus ob peb vas, psychosis, aggressive xeev, agitation, suicidal xav thiab kev nyuaj siab. Tib lub sijhawm, tsis yog txhua tus neeg uas noj tshuaj thiab txiav luam yeeb tau ntsib kev ua txhaum cai.
Yog tias koj muaj kev nyuaj siab lossis lwm yam teeb meem, koj yuav tsum sab laj nrog kws kho mob tam sim ntawd thiab tsis txhob noj tshuaj lossis txo nws cov koob tshuaj. Hauv qhov no, cov tsos mob no feem ntau ploj mus. Txhawm rau txiav txim siab tias muaj qhov tshwm sim ntawm qhov tshwm sim ntawm psychoneurological pathologies, nws raug nquahu kom ua qhov kev ntsuam xyuas ua ntej pib cov tshuaj rau qhov muaj kev tsis sib haum xeeb yav dhau los thiab tam sim no. Yog tias muaj, Champix yuav tsum tau noj tsuas yog raws li tus kws tshaj lij qhia. Qhov no yog vim qhov tseeb tias kev haus luam yeeb nws tus kheej tuaj yeem ua rau muaj kev cuam tshuam ntawm cov kab mob uas twb muaj lawm, xws li schizophrenia, kev nyuaj siab, neurosis, thiab lwm yam.
Nws tseem tsim nyog xav txog tias kev xav tua tus kheej thiab kev nyuaj siab tuaj yeem nrog tus neeg haus luam yeeb, tsis hais nws haus tshuaj lossis tsis haus. Thaum lub sijhawm tshem tawm ntawm nicotine, nws tuaj yeem yooj yim kom paub qhov txawv ntawm kev nyuaj siab thiab neurosis cuam tshuam nrog. Yog li ntawd, nco ntsoov npaj rau tej yam tsis kaj siab surprises. Tawm tsam keeb kwm yav dhau los ntawm kev siv tshuaj "Champix" hauv cov neeg uas raug kev txom nyem los ntawm cov kab mob ntawm cov hlab plawv, muaj kev nce ntxiv hauv qhov tshwm sim ntawm ntau yam pathologies thiab teeb meem. Txawm hais tias muaj kev pheej hmoo siab ntawm cov kev mob tshwm sim, kev tuag ntawm cov neeg noj cov tshuaj tau qis dua piv rau cov neeg uas tsis siv cov tshuaj no los txiav luam yeeb. Muab qhov xwm txheej ntawm lub xeev no, peb tuaj yeem xaus lus tias cov tib neeg raug mob los ntawm cov kab mob plawv thiab noj Champix yuav tsum ua tib zoo saib xyuas lawv txoj kev noj qab haus huv. Thaum thawj cov tsos mob tshwm sim thiab lawv hnyav dua, nws raug nquahu kom nrhiav kev pab kho mob tam sim.
Champix muaj lwm yam kev phiv dab tsi? Kev tshuaj xyuas cov neeg haus luam yeeb thiab cov kev mob tshwm sim - qhov no yog cov ntaub ntawv uas feem ntau nyiam rau cov neeg mob. Qee zaum, cov tshuaj tuaj yeem ua rau qaug dab peg, tshwj xeeb tshaj yog nyob rau hauv cov neeg uas tsis tau raug kev txom nyem los ntawm cov teeb meem no ua ntej. Vim li no, cov neeg uas muaj mob qaug dab peg yuav tsum noj Champix nrog ceev faj heev. Nws raug nquahu kom ua qhov no raws li tus kws kho mob saib xyuas.
Champix ua rau muaj kev nyuaj siab, chim siab, thiab insomnia li ntawm peb feem pua ntawm cov neeg mob. Tsis tas li ntawd, muaj kev xav ntau ntxiv rau kev haus luam yeeb. Muaj tsawg zaus, cov tshuaj ua rau muaj kev tsis haum tshuaj. Lawv tuaj yeem pom lawv tus kheej nyob rau hauv cov tsos ntawm angioedema hauv tus nplaig, daim di ncauj, larynx, cov pos hniav thiab sab. Cov mob no tuaj yeem ua rau tuag taus. Thaum thawj qhov tshwm sim ntawm edema, nws yog ib qho tsim nyog yuav tsum tau mus rau lub tsev kho mob sai. Hauv qhov no, nws yog qhov zoo dua kom tsis txhob noj tshuaj. Muaj tsawg zaus, kev siv Champix provokes kev loj hlob ntawm kev ua xua ntawm daim tawv nqaij. Qee zaum muaj erythema multiforme thiab Stevens-Johnson syndrome.
Muaj peev xwm tsav tsheb thiab tshuab ua haujlwm
qhov teeb meem no yuav tsum tau muab tshwj xeeb. Nws cuam tshuam li casmuaj peev xwm tsav tsheb coj Champix? Kev tshuaj xyuas cov neeg haus luam yeeb, cov lus qhia thiab cov lus qhia los ntawm kws kho mob tau lees paub tias cov tshuaj tuaj yeem ua rau qaug zog thiab kiv taub hau. Thaum lub sij hawm kho, koj yuav tsum tso tseg cov dej num uas yuav tsum muaj kev kub ceev ntawm cov tshuaj tiv thaiv, kev mloog thiab kev xav.
Ntau tshaj
Yuav ua li cas coj Champix kom raug? Kev tshuaj xyuas cov kws kho mob, cov kev mob tshwm sim thiab cov lus qhia rau kev siv - yog qhov koj yuav tsum tau kawm ua ntej pib kawm. Thaum lub sij hawm tag nrho ntawm kev soj ntsuam, tsis muaj cov ntaub ntawv ntawm overdose tau sau npe. Txawm li cas los xij, txoj kev xav, thaum kuaj pom, nws yog qhov tsim nyog los kho cov tsos mob, txhawm rau tswj kev ua haujlwm ntawm lub cev tseem ceeb thiab lub cev.
Kev sib tham nrog tshuaj
Nws puas tuaj yeem siv nrog lwm yam tshuaj Champix? Kev tshuaj xyuas ntawm cov neeg haus luam yeeb thiab cov kev mob tshwm sim hauv lub pob tsis paub meej tias muaj kev cuam tshuam tseem ceeb hauv kev kho mob nrog lwm cov tshuaj. Koj tuaj yeem yooj yim siv Champix ua ke nrog txhua yam tshuaj yam tsis tau hloov cov koob tshuaj. Txawm li cas los xij, yog tias ib tus neeg muaj mob hnyav uas yuav tsum tau noj tshuaj hnyav, nws tseem tsim nyog tau txais cov lus qhia tshwj xeeb.
Koj yuav tsum tsis txhob siv cov ntsiav tshuaj Champix nrog dab tsi? Kev tshuaj xyuas ntawm cov kws kho mob qhia tias cov tshuaj yuav tsum tsis txhob noj ua ke nrog Cimetidine. Cov khoom xyaw nquag ntawm cov tshuaj no tau tawm los ntawm lub raum. "Warfarin" nrog "Champix" tsis cuam tshuam nrog txhua txoj kev. Txawm li cas los xij, thaum koj txiav tawm nicotine, qhov concentration ntawm cov tshuaj no tuaj yeem nce ntxiv.
Leej twg ntxivKuv puas yuav tsum siv Champix? Kev tshuaj xyuas ntawm cov neeg haus luam yeeb paub meej tias cov tshuaj tuaj yeem txhim kho cov nyhuv tshuaj lom ntawm cawv. Tab sis kev tshawb fawb tsis tau lees paub qhov kev sib raug zoo ntawm kev noj tshuaj hauv nqe lus nug thiab txhim kho cov nyhuv ntawm cov dej cawv.
Reviews
Champix puas muaj txiaj ntsig? Kev tshuaj xyuas hais tias cov cuab yeej no pab kom txiav luam yeeb. Txawm li cas los xij, nws muaj ntau yam kev phiv. Yog li ntawd, ntau yam tshaj tawm tias muaj zog excitability thiab nervousness. tremor, psychosis, thiab ntxhov siab vim kuj tshwm sim. Nyob rau hauv lub xub ntiag ntawm cov kab mob ntev, "Champix" tuaj yeem ua rau lawv exacerbation. Txawm li cas los xij, nrog kev siv kom raug, cov tshuaj muaj cov txiaj ntsig zoo. Raws li cov neeg mob, qhov tseem ceeb tshaj plaws yog tsis txwv txoj kev kho mob.
Zoo kawg
Hnub no muaj tsawg tus uas tsis raug kev txom nyem. Tab sis ua li ntawd, yog tias koj ua rau ib yam dab tsi, nws yeej tsis lig dhau los muab nws. Tsis txhob ua rau tus cwj pwm phem! Ua lub neej noj qab nyob zoo, koom nrog ntau yam kis las, ua raws li kev noj zaub mov kom raug. Saib xyuas koj tus kheej thiab koj txoj kev noj qab haus huv!
