Cov tshuaj Antithyroid: kev faib tawm, npe

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Cov tshuaj Antithyroid: kev faib tawm, npe
Cov tshuaj Antithyroid: kev faib tawm, npe

Video: Cov tshuaj Antithyroid: kev faib tawm, npe

Video: Cov tshuaj Antithyroid: kev faib tawm, npe
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Cov teeb meem thyroid cuam tshuam rau tus lej tseem ceeb ntawm cov pej xeem ntawm tag nrho lub ntiaj teb. Muaj ntau qhov laj thawj rau qhov no, tab sis nrog rau cov kab mob uas tau pom los ntawm kev tsim cov thyroid hormones ntau ntxiv, cov tshuaj hu ua antithyroid kuj tseem pab tiv thaiv. Cov tshuaj no yog dab tsi, lawv pab lub cev li cas thaum siv?

Thyroid problems

Cov thyroid caj pas yog ib lo lus paub rau txhua tus, thiab ntau tus txawm paub tias nws nyob qhov twg - nyob rau hauv qis qis ntawm lub larynx. Tab sis dab tsi yog nws lub luag haujlwm rau tib neeg lub cev? Cov thyroid caj pas yog ib feem ntawm lub complex endocrine system uas yog lub luag hauj lwm rau tag nrho cov txheej txheem tshwm sim nyob rau hauv lub cev. Cov thyroid caj pas, tshwj xeeb tshaj yog, tsim ob yam tshuaj hormones tseem ceeb - thyroxine thiab triiodothyronine, uas koom nrog hauv cov txheej txheem metabolic, hauv cov txheej txheem ntawm kev loj hlob thiab kev loj hlob ntawm cov ntaub so ntswg thiab kabmob. Thyrokaceltonin kuj yog tsim los ntawm cov thyroid hlwb - ib yam tshuaj uas lub luag hauj lwm rau phosphorus-calcium metabolism, thiab li no rau cov mob ntawm tib neeg cov pob txha thiab cov hniav.

tshuaj antithyroid
tshuaj antithyroid

Yam tsis tsim nyog

Nws yuav zoo li tias txij li cov thyroid caj pas tsim cov tshuaj hormones tseem ceeb, qhov ua haujlwm ntau dua, nws yuav tsum zoo dua, txhua yam txheej txheem yuavmus nrawm dua thiab muaj zog dua. Tab sis qhov tseeb, nws tsis zoo li ntawd kiag li. Xwm muaj qhov sib npaug ntawm txhua yam uas nyob hauv nws, thiab tib neeg endocrine system tshwj xeeb. Yog tias cov thyroid caj pas ua haujlwm dhau los, ces qhov no ua rau muaj kev cuam tshuam tsis zoo rau lub xeev ntawm lub cev, txawm li cas los xij, qhov tsis muaj cov thyroid hormones kuj tseem muaj ntau yam teeb meem. Kev ua haujlwm ntawm cov thyroid caj pas ua rau hyperthyroidism lossis thyrotoxicosis.

hluavtaws antithyroid tshuaj
hluavtaws antithyroid tshuaj

antithyroid txhais li cas?

Yog cov thyroid caj pas ua haujlwm dhau, ces cov tshuaj tiv thaiv thyroid pab tiv thaiv nws. Los ntawm lub npe ntawm cov tshuaj no nws yog tseeb hais tias lawv ua hauj lwm tawm tsam - tawm tsam cov thyroid caj pas. Cov tshuaj no tseem hu ua thyreostatics. Cov tshuaj muaj nyob rau hauv cov pab pawg ntawm cov tshuaj antithyroid tso cai rau koj mus normalize cov kev ua ntawm cov thyroid caj pas, txo nws cov kev ua, thiab yog li ntawd txo cov thyroid hormones.

cov npe ntawm cov tshuaj antithyroid
cov npe ntawm cov tshuaj antithyroid

Kev faib tawm ntawm cov tshuaj antithyroid

tshuaj kho mob uas pab tawm tsam cov thyroid caj pas ntau dhau hu ua "cov tshuaj tiv thaiv thyroid". Lawv qhov kev faib tawm tau lees paub thoob plaws ntiaj teb thiab muaj peb pawg tshuaj uas ua rau cov tshuaj tiv thaiv cov thyroid hormones:

  • tshuaj uas cuam tshuam kev tsim cov tshuaj iodine hauv cov thyroid caj pas nws tus kheej;
  • tshuaj uas txo cov iodine uptake los ntawm cov thyroid epithelial hlwb;
  • tshuaj ua kom puas tsuajiodine hauv cov thyroid caj pas.

Txhua yam tshuaj muaj cov qauv tshuaj sib txawv, thiab hom kev ua ntawm cov tshuaj nyob ntawm nws.

tshuaj antithyroid tshuaj
tshuaj antithyroid tshuaj

Iodine as tshuaj

Cov thyroid hormones yog tsim los ntawm cov thyroid epithelial hlwb uas ntes iodine. Yog tias cov tshuaj no ntxiv rau tib neeg lub cev, qhov txo qis hauv biosynthesis ntawm cov thyroid hormones tshwm sim. Kuj tseem muaj kev ua txhaum cai ntawm lub caj pas kom nqus iodine hauv cov ntshav. Pharmaceutics muaj ob hom kev npaj iodine koom nrog hauv kev txo qis kev ua haujlwm ntawm cov thyroid caj pas:

  • inorganic iodine - raws li cov tshuaj ntuj tsim;
  • organic iodine li synthesized diiodotyrosine, ib feem ntawm thyroglobulin, ib qho protein tshwj xeeb ntawm cov thyroid caj pas nws tus kheej.

Cov tshuaj ntawm cov organic keeb kwm muaj cov cuab yeej antithyroid, uas yog nquag siv hauv lub sijhawm ua ntej ntawm cov neeg mob uas muaj kab mob goiter, nrog rau kev tiv thaiv cov teeb meem hauv lub sijhawm postoperative. Ntau yam ntawm cov tshuaj no muaj cov khoom xyaw nquag ntawm levothyroxine sodium. Inorganic iodine yog tshuaj tsis tau tsuas yog rau kev kho mob ntawm hyperactive thyroid caj pas, tab sis kuj raws li ib tug prophylactic. Txawm hais tias zoo li muaj kev nyab xeeb, cov tshuaj tiv thaiv kab mob nrog iodine, txawm li cas los xij, zoo li lwm yam tshuaj, yuav tsum tau noj raws li kws kho mob qhia.

Cov tshuaj hluavtaws muaj cov nyhuv antithyroid
Cov tshuaj hluavtaws muaj cov nyhuv antithyroid

Thiourea, nws cov derivatives thiabhyperthyroidism

Cov tshuaj uas pab txo qis cov thyroid caj pas ntau dhau, cov tshuaj hu ua antithyroid tuaj yeem muab faib ua ob hom - ntuj, ntuj, tshuaj xws li iodine, thiab tshuaj hluavtaws tau txais los ntawm cov txheej txheem tshuaj lom neeg.. Cov tom kawg suav nrog thiourea thiab nws cov derivatives - propylthiouracil, 1-methyl-2-mercaptoimidazole, 2-carboethoxymercapto-1-methylimidazole, 6-methylthiouracil. Ib qho tshuaj antithyroid hluavtaws raws li thiourea derivatives tuaj yeem txo cov iodine metabolism hauv cov thyroid caj pas los ntawm kev txo cov txheej txheem metabolic ntawm iodine hauv cov thyroid caj pas nws tus kheej.

Kev faib tawm ntawm cov tshuaj antithyroid
Kev faib tawm ntawm cov tshuaj antithyroid

Cov tshuaj twg pab nrog cov thyroid ua haujlwm dhau?

Thiourea derivatives thiab iodine yog ib feem ntawm cov tshuaj nrov siv los ua cov tshuaj tiv thaiv thyroid. Cov tshuaj hluavtaws twg muaj cov tshuaj tiv thaiv thyroid? Cov npe ntawm cov nyiaj no txawv, tab sis ntawm no yog cov khoom xyaw tseem ceeb:

  • Ythiamazole;
  • Ypropylthiouracil.

Thiamazol txo cov txheej txheem metabolic ntawm iodine hauv cov thyroid caj pas, yog li txo nws txoj haujlwm. Cov tshuaj no yog lub hauv paus ntawm cov tshuaj xws li Mercazolil, Tyrozol, Thiamzol, Metizol.

Propylthiouracil inhibits kev hloov pauv ntawm iodine hauv cov thyroid caj pas, yog li txiav txim siab nws txoj kev sib raug zoo rau ib pawg hu ua tshuaj tiv thaiv thyroid. Kev npaj raws li propylthiouracil ntau zaustag nrho cov raug muab rau siv nyob rau hauv Western Europe. Hauv peb lub tebchaws, cov khw muag tshuaj muag cov tshuaj nkaus xwb raws li propylthiouracil - Propicil.

tshuaj antithyroid
tshuaj antithyroid

Vim cov tshuaj rau kev kho mob hyperthyroidism thiab thyrotoxicosis muaj ntau yam kev mob tshwm sim ntawm kev mob plawv, paj hlwb, thiab daim siab, cov tshuaj concomitant tau sau ua ke nrog cov tshuaj no.

Hauv kev kho qee cov kab mob ntawm cov thyroid caj pas, siv cov xov tooj cua iodine, uas, thaum nws nkag mus rau hauv tus neeg mob lub cev, raug ntes los ntawm cov hlwb ntawm cov thyroid caj pas thiab muaj kev puas tsuaj rau nws, txo kev ua haujlwm thiab nce zus tau tej cov tshuaj hormones. Cov tshuaj no muab cov txiaj ntsig zoo tshaj plaws tsuas yog tom qab tshem tawm tag nrho cov thyroid caj pas - thyroidectomy, txij li cov khoom siv hluav taws xob thaum kawg rhuav tshem cov hlwb ntawm lub cev. Txawm li cas los xij, ntau tus neeg mob uas muaj cov thyroid caj pas ntau dhau tau raug tshuaj radioactive iodine npaj rau normalize tus mob.

hluavtaws antithyroid tshuaj
hluavtaws antithyroid tshuaj

Tsuas yog los ntawm kev teem sijhawm

Cov kab mob thyroid tsuas yog txiav txim siab los ntawm txoj kev kuaj mob - kuaj, ultrasound, MRI lossis CT. Nws yog tsis yooj yim sua kom kuaj tau tus kab mob thyroid nkaus xwb los ntawm kev noj anamnesis thiab los ntawm cov lus ntawm tus neeg mob! Tab sis thaum qhov teeb meem raug txheeb xyuas, tus kws kho mob muaj peev xwm sau tau cov tshuaj zoo, suav nrog txhua yam tshwj xeeb. Tag nrho cov tshuaj rau kev kho mob ntawm hyperthyroidism thiab thyrotoxicosis tshwm sim los ntawmnce kev tsim khoom ntawm cov thyroid caj pas, muaj ntau yam kev phiv thiab daim ntawv thov nta. Piv txwv li, qhov cuam tshuam tsis zoo yuav tshwm sim thaum cov tshuaj uas pab txo qis kev nqus ntawm iodine los ntawm cov thyroid cov ntaub so ntswg los ua ib qho kev txhawb rau nws cov haujlwm los tsim cov tshuaj hormones uas ploj lawm tom qab qee lub sijhawm. Tus kab mob rov qab los. Kev kho mob ntawm hyperthyroidism thiab thyrotoxicosis yog ib txwm ib tus neeg. Thaum kuaj tau qhov tseeb, tsis muaj teeb meem koj yuav tsum tau kho tus kheej. Tsuas yog xaiv txoj kev kho kom zoo xwb thiaj li tso cai rau tsis suav nrog kev phais mob thiab siv cov tshuaj hormonal tshwj xeeb rau lub neej.

cov npe ntawm cov tshuaj antithyroid
cov npe ntawm cov tshuaj antithyroid

Cov tshuaj Antithyroid tsis yog cov khoom pov thawj ntawm cov chaw muag tshuaj, tab sis lawv yog cov ntsiab lus tseem ceeb tshaj plaws hauv kev saib xyuas kev noj qab haus huv thiab txawm lub neej ntawm ntau tus neeg mob uas muaj cov thyroid caj pas.

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