Rau txoj kev tshawb fawb ntawm cov ntshav txhaws, cov kws kho mob tau sau tshuaj ntsuam tshwj xeeb - coagulogram. Nrog rau qhov kev sim no, koj tuaj yeem txiav txim siab qhov nyiam ntawm thrombosis thiab nce los ntshav. Ib qho ntawm cov cim tseem ceeb ntawm kev tsom xam yog qhov concentration ntawm fibrinogen. Nrog rau ntau yam pathologies, qib ntawm cov protein no nce siab tshaj li qub, uas ua rau muaj kev pheej hmoo ntawm vascular blockage. Puas tuaj yeem txo qis fibrinogen? Thiab yuav ua li cas? Peb yuav teb cov lus nug no hauv kab lus.
Fibrinogen yog cov protein uas tsim tawm hauv daim siab hlwb. Thaum cuam tshuam nrog cov enzymes, nws hloov mus rau hauv fibrin threads thiab koom rau hauv cov txheej txheem coagulation. Cov protein no xav tau los ntawm lub cev los tsim cov ntshav txhaws thiab tiv thaiv hemorrhage.
nce qib ntawm cov protein no hu ua hyperfibrinogenemia. Nyob rau hauv cov ntaub ntawv no, tus neeg mob cov ntshav viscosity nce thiab kev pheej hmoo ntawmthrombus tsim. Yog li ntawd, nws yog ib qho tseem ceeb heev kom txo cov fibrinogen hauv lub sij hawm los tiv thaiv cov hlab ntsha.
Tsis muaj qhov txaus ntshai yog qhov tsis tshua muaj siab ntawm fibrinogen. Qhov tsis txaus ntawm cov protein no ua rau muaj ntshav ntau ntxiv thiab ntshav ntshav.
Analysis
Yuav ua li cas thiaj paub cov qib fibrinogen? Cov qib ntawm cov protein no yog txiav txim siab raws li ib feem ntawm coagulogram - kuaj ntshav rau ntshav txhaws. Biomaterial rau kev tshawb fawb yog muab los ntawm cov leeg.
Ntshav tau muab tso rau hauv lub centrifuge, plasma cais tawm ntawm nws thiab sib xyaw nrog cov enzyme - thrombin. Qhov no ua rau cov ntshav txhaws. Nws yog cais los ntawm plasma thiab hnyav. Qhov loj ntawm cov hlab ntsha yog sib npaug los ntawm qhov zoo ntawm 0.222 thiab qhov ntsuas fibrinogen tau txais. Nws yog ntsuas hauv grams ib liter ntawm cov ntshav (g / L).
Coagulogram yog sau rau ntau yam pathologies nrog rau kev ua txhaum ntawm cov ntshav txhaws, ua ntej kev phais, thiab thaum cev xeeb tub. Qhov kev tshuaj ntsuam no yog ua rau cov neeg laus rau kev tiv thaiv, nws tso cai rau koj los ntsuas qhov kev pheej hmoo ntawm kev tsim myocardial infarction thiab atherosclerosis.
Norma
Cov qib fibrinogen ib txwm rau cov neeg laus yog nyob nruab nrab ntawm 2 txog 4 g / L. Qib ntawm cov protein no nce thaum cev xeeb tub. Thaum lub sij hawm cev xeeb tub, tus nqi ntawm 6 mus rau 7 g / l raug suav hais tias yog tsim nyog. Qhov no yog qhov txawv ntawm cov qauv thiab tsis qhia txog pathology.
Cov menyuam mos yug tshiab tsim cov fibrinogen tsawg dua li cov neeg laus. Cov qauv rau menyuam mos yog los ntawm 1.25 txog 3 g / l.
Yog vim li cas nce
Fibrinogen qib yuav siab dua li ib txwm yog tias tus neeg mob raug kev txom nyem los ntawm cov kab mob hauv qab no:
- Kab mob sib kis thiab mob. Fibrinogen yog ib theem mob hnyav protein. Nws yog tsim nyob rau hauv ib qho ntxiv thaum cov kab mob nkag mus rau hauv lub cev. Qhov no yog ib qho kev tiv thaiv ntuj tiv thaiv ntawm lub cev tiv thaiv kab mob. Cov ntshav txhaws maj mam kis tus kab mob. Txhawm rau txo cov fibrinogen, nws yog ib qho tsim nyog yuav tsum tau mus kawm cov kab mob tua kab mob lossis tshuaj tua kab mob.
- Ntshav Qab Zib. Yog tias qhov tsis txaus insulin tsim nyob rau hauv lub cev, ces hepatocytes tsim fibrinogen ntau ntxiv. Qhov no yog vim cov kab mob metabolic.
- Autoimmune pathologies. Hauv cov kab mob lupus erythematosus, scleroderma, thiab mob caj dab rheumatoid, lub cev tiv thaiv kab mob tsim cov tshuaj tiv thaiv rau lawv cov ntaub so ntswg. Qhov no yog nrog los ntawm cov tshuaj tiv thaiv inflammatory thiab thickening ntawm cov ntshav. Txhawm rau txo cov fibrinogen, nws yog ib qho tsim nyog kom ua tiav qhov kev tso tawm ruaj khov ntawm cov kab mob hauv qab.
- Kab mob siab mob siab. Nrog rau kab mob siab, kev ua haujlwm ntawm cov hlwb ntawm lub cev raug cuam tshuam. Qhov no feem ntau nrog los ntawm kev nce hauv fibrinogen concentration.
- Burns. Nrog thermal thiab tshuaj daim tawv nqaij mob, vascular permeability nce. Qhov no ua rau txo qis hauv cov ntshav ntim thiab nce hauv cov concentration ntawm fibrinogen.
- kab mob Oncological ntawm cov kab mob hematopoietic. Ntshav qog noj ntshav feem ntau ua rau lub siab metastases thiab mob hyperfibrinogenemia.
- Nephrotic syndrome. Qhov no pathologytus cwj pwm los ntawm lub raum tsis zoo. Cov kab mob excretory tso tawm ntau cov protein ntau, suav nrog fibrinogen, nrog rau cov zis. Txhawm rau them nyiaj rau nws qhov tsis txaus, lub siab pib tsim cov protein ntau ntau.
- Kev rog. Hauv cov neeg rog rog, daim siab ua haujlwm tsis zoo. Qhov no feem ntau ua rau kev tsim cov fibrinogen ntau dhau.
Tseem kuj tseem muaj qhov ua rau tsis muaj kab mob ua rau muaj zog fibrinogen. Qib ntawm cov protein no nce nrog lub cev qhuav dej, kev tsim txom ntawm cov khoom noj rog thiab cawv, thiab haus luam yeeb. Cov ntshav txhaws feem ntau raug sau tseg hauv cov neeg laus vim muaj hnub nyoog hloov pauv hauv lub cev.
Yuav ua li cas yog tias fibrinogen nce siab? Yuav ua li cas txo qis cov protein no thiab txo qhov kev pheej hmoo ntawm thrombosis? Muaj ntau txoj hauv kev los txo cov ntshav. Tom ntej no, peb yuav saib lawv kom ntxaws ntxiv.
Drug therapy
Yuav ua li cas txo cov fibrinogen hauv cov ntshav nrog tshuaj? Ua ntej tshaj plaws, nws yog ib qho tsim nyog los kho cov kab mob hauv qab. Tom qab tag nrho, hyperfibrinogenemia feem ntau pom tawm tsam keeb kwm ntawm ntau yam pathologies. Kev nce qib ntawm fibrinogen tsuas yog ib qho ntawm qhov tshwm sim ntawm tus kab mob.
Txhawm rau tiv thaiv kev tsim cov ntshav txhaws thiab txhaws ntawm cov hlab ntsha, cov tshuaj hauv qab no tau sau tseg:
- Antiaggregants. Cov tshuaj no tiv thaiv cov qe ntshav liab thiab platelets los ntawm kev sib txuas thiab ua ke. Lawv artificially nyias cov ntshav. Cov pab pawg no suav nrog cov tshuaj raws li acetylsalicylic acid: Cardiomagnyl, AspirinCardio", "Aspecard".
- Anticoagulants. Cov tshuaj no txo cov ntshav txhaws. Cov tshuaj feem ntau siv yog Clexane. Nws txo cov kev ua ntawm cov ntshav txhaws thiab tiv thaiv cov ntshav txhaws.
- YFibrinolytics. Cov tshuaj no tsuas yog muab tshuaj rau lub sijhawm ntev hyperfibrinogenemia thiab xav tias thrombosis. Lawv cov khoom xyaw nquag pab txhawb rau kev sib cais ntawm cov ntshav txhaws. Cov nyiaj no suav nrog "Fibrinolysin" thiab "Streptokinase".
Tag nrho cov tshuaj saum toj no tsuas yog siv tau raws li kws kho mob tau sau tseg. Yog tias noj tsis raug, cov tshuaj no tuaj yeem ua rau los ntshav sab hauv.
Kev noj haus
Yuav ua li cas txo fibrinogen los ntawm kev noj zaub mov? Nws yog ib qho tsim nyog kom tshem tawm cov khoom noj uas ua rau cov ntshav txhaws los ntawm kev noj haus:
- qab zib thiab khoom qab zib;
- yuav haus dej cawv;
- qos;
- fatty food;
- smoked nqaij;
- bananas;
- buckwheat tais diav;
- sweet soda.
Raws li koj paub, tib neeg cov ntshav yog 90% dej. Yog li ntawd, nws yog ib qho tseem ceeb heev los tiv thaiv lub cev qhuav dej thiab ua raws li kev noj haus kom raug. Yam tsawg kawg 2 - 2.5 litres ntawm cov kua yuav tsum tau noj ib hnub twg. Nws tuaj yeem yog cov dej ntim zoo, ntsuab lossis mint tshuaj yej, cov kua txiv hmab txiv ntoo tshiab los ntawm zaub, txiv hmab txiv ntoo thiab txiv hmab txiv ntoo.
Koj yuav tsum muaj cov khoom noj uas txo cov fibrinogen hauv koj cov zaub mov. Rau lawvsuav nrog:
- kua txob liab;
- txiv roj roj;
- citrus txiv hmab txiv ntoo (txiv kab ntxwv, txiv qaub);
- grenades;
- fig;
- qej;
- beets;
- hiav txwv ntses;
- qhiav;
- seafood;
- squash.
Nws yog ib qho tseem ceeb heev los saib xyuas cov ntsiab lus calorie ntawm cov khoom noj. Kev noj ntau dhau ua rau muaj ntshav viscosity ntau ntxiv. Nws yog ib qho tsim nyog los txwv kev noj cov rog thiab carbohydrates. Cov zaub mov yuav tsum tau noj tib lub sijhawm, tsawg kawg 5 - 6 zaug hauv ib hnub hauv qhov me me.
tshuaj ntsuab
Cov tshuaj pej xeem puas tuaj yeem txo qis fibrinogen? Feem ntau, cov neeg mob hyperfibrinogenemia xav tau kev kho mob. Txawm li cas los xij, kev kho mob hauv tsev tuaj yeem yog qhov zoo ntxiv rau kev kho tshuaj.
Cov tshuaj ntsuab hauv qab no yuav pab txo cov ntshav viscosity:
- paj paj. 30 g ntawm raw cov ntaub ntawv yuav tsum tau brewed nyob rau hauv 1 liter ntawm boiling dej. Cov tshuaj yog lim thiab haus 1/2 khob ob zaug ib hnub twg. Txawm li cas los xij, kev kho mob zoo li no yuav tsum tau koom tes nrog kws kho mob, vim tias qab zib clover muaj kev phiv.
- White willow bark. Qhov no yog ib tug muaj zog ntuj anticoagulant, nws muaj ib tug zoo xws li cov tshuaj aspirin. Cov chaw muag tshuaj muag cov ntsiav tshuaj npaj ua "White Willow Bark". Yuav kom txo cov ntshav, lawv noj 1 daim 2-3 zaug hauv ib hnub.
- Kua cider vinegar. Cov khoom no tshem tawm toxins los ntawm lub cev thiab thins cov ntshav. Ntxiv 2 tablespoons txiv apple cider vinegar rau ib khob dej. Cov npaj muaj pes tsawg leeg yog qaug cawv thaum sawv ntxov. Cov tshuaj no yog contraindicated nyob rau hauv cov neeg mob uas muaj kab mob gastrointestinal.
- Kombucha. Cov dej haus no muaj cov kua qaub (acetic, citric, oxalic) uas ua raws li cov tshuaj tiv thaiv kab mob ntuj.
Cov kev kho mob ntshav qab zib tsis pom zoo ua ntej kev phais, nrog rau hemorrhoids thiab ua ntej kev coj khaub ncaws. Lawv tuaj yeem ua rau los ntshav hnyav.
Nyob zoo ib tsoom niam txiv kwv tij neej tsas sawv daws.
Yuav ua li cas txo fibrinogen thaum cev xeeb tub? Ib qib siab ntawm cov protein no tuaj yeem ua rau placental abruption, impaired fetal txoj kev loj hlob, thrombosis ntawm txoj hlab ntsha qaum thiab fetal tuag. Txhawm rau zam qhov tshwm sim zoo li no, nws yog ib qho tsim nyog yuav tsum tau kuaj xyuas kom paub meej tias qhov ua rau hyperfibrinogenemia. Muaj ntau cov tshuaj yog contraindicated rau cov poj niam cev xeeb tub. Tsuas yog tus kws kho mob tuaj yeem xaiv cov tshuaj ntshav kom zoo.
Nrog cov fibrinogen nce ntxiv, tus niam expectant yuav tsum noj kom raug. Koj yuav tsum tsis tu ncua suav nrog nqaij nruab deg, tshuaj yej ntsuab, zaub thiab txiv hmab txiv ntoo hauv koj cov zaub mov. Koj tuaj yeem siv cov tshuaj pej xeem, tab sis ua ntej koj yuav tsum sab laj nrog tus kws kho mob hauv obstetrician-gynecologist.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias txo cov fibrinogen thaum cev xeeb tub yuav tsum ua tib zoo ua tib zoo. Kev poob qis hauv qib ntawm cov protein no yuav tsum tsis txhob tso cai. Nws qhov tsis txaus tuaj yeem ua rau preeclampsia, thiab tom qab ntawd ua rau ntshav poob loj heev thaum yug menyuam. Yog li, kev kho mob ntawm hyperfibrinogenemia hauv cov poj niam cev xeeb tub yuav tsum tau ua raws li kev saib xyuas ntawm tus kws kho mob.
Zoo kawg
Kev siab siab ntawm fibrinogen tuaj yeem ua rau muaj kev phom sij txaus ntshai. Kom zamcov teeb meem loj, nws yog ib qho tsim nyog yuav tsum tau mus rau hauv chav kawm ntawm txoj kev kho mob. Nws yog ib qho tsim nyog tsis yog yuav tsum tsis tu ncua noj cov tshuaj uas kws kho mob tau sau tseg, tab sis kuj yuav tsum tsis txhob siv cov khoom uas ua rau cov ntshav txhaws. Qhov no yuav pab tiv thaiv cov ntshav txhaws. Thaum muaj hnub nyoog laus, nws yog ib qho tsim nyog yuav tsum tau ua ib coagulogram tsis tu ncua, qhov no yuav zam qhov tshwm sim ntawm cov hlab plawv pathologies.
