Löfgren's syndrome yog ib qho symmetrical o ntawm basal bronchopulmonary nodes ntawm lymphatic system ntawm ob sab. Tus kab mob no nrog rau ntawm daim tawv nqaij manifestations (erythema nodosum), lub cev kub thiab arthralgia. Cov tsos mob no yog yam ntxwv ntawm sarcoidosis.
Tus kab mob no cuam tshuam rau lub cev sib txawv - ntsws, spleen, lymph nodes. Löfgren's syndrome nrog sarcoidosis tsis kis thiab tsis yog kis kab mob. Tsis txhob cuam tshuam tus kab mob nrog cov txheej txheem oncological thiab tuberculosis.
daim duab kho mob
Sarcoidosis yog ib yam kab mob uas tsis tshua muaj rau lub sijhawm ntev, tab sis hnub no daim duab tau hloov pauv, cov kab mob kis tau nrawm thoob plaws ntiaj teb. Raws li kev txheeb cais, cov poj niam hnub nyoog 20 txog 40 xyoo raug kev txom nyem tshaj plaws los ntawm Löfgren's syndrome, tab sis tus kab mob tuaj yeem tuaj rau txhua tus.
Nws tuaj yeem yog asymptomatic, maj mam lossis mob. Ib lub chaw kho mob asymptomatic, raws li txoj cai, raug kuaj pom los ntawm lub sijhawm thaum kuaj kev tiv thaiv fluorographic. Feem ntau yog cov chav kawm maj mam thiab kev loj hlob ntawm tus kab mob nrog cov cim hauv qab no:
- ua tsis taus pa ntawm kev tawm dag zog;
- ruammob hauv siab;
- mob ntawm lub xub pwg hniav;
- hnoos qhuav;
- subfebrile kub;
- qaug zog thiab qaug zog;
- tawm hws ntau dhau;
- poob qab los;
- mob hauv pob qij txha, sab nraub qaum.
Cov kab mob hnyav ntawm sarcoidosis hu ua Löfgren's syndrome thiab nrog kub taub hau mus txog 38-39 ° C, mob pob qij txha, daim tawv nqaij mob nyob rau hauv daim ntawv ntawm erythema, mob hauv siab thiab ua tsis taus pa. Muaj ntau zaus nyob rau hauv cov kev mob hnyav ntawm kev rov ua tiav ntawm tus neeg uas tsis siv tshuaj kho thiab lwm yam kev cuam tshuam.
Etiology ntawm tus kab mob
Txog thaum kawg ntawm cov tshuaj, qhov ua rau ntawm tus kab mob no tsis paub, nws zoo li cov hauv qab no tuaj yeem ua rau nws txoj kev loj hlob:
- kab mob, tuberculosis microbacteria, kab mob siab C;
- yam tsis zoo sab nraud, nqus plua plav hlau;
- haus luam yeeb, uas tsis yog lub hauv paus ua rau, tab sis ua rau muaj kev cuam tshuam rau cov kab mob;
Kev Tiv Thaiv Kab Mob sarcoidosis
Nws yog ib qho tseem ceeb rau cov neeg mob uas muaj Löfgren's syndrome kom tsis txhob haus luam yeeb thiaj li ua kom rov zoo. Nws yog ib qho tsim nyog yuav tsum kuaj xyuas lub cev ntawm lub hauv siab txhua 2 xyoos. Muab rau hauv tus account tias etiology ntawm tus kab mob tsis paub tag nrho, cov hauv paus ntsiab lus ntawm kev tiv thaiv tsis tau tsim. Cov kws tshaj lij pom zoo kom tsis txhob sib cuag nrog cov plua plav hlau thiab foci ntawm cov kab mob sib kis.
Löfgren's syndrome nyob rau hauv sarcoidosis yog kuaj pom los ntawm cov nram qab no extrapulmonary localization ntawm cov txheej txheem -kev puas tsuaj rau cov ntaub so ntswg subcutaneous, daim tawv nqaij thiab peripheral lymph nodes. Muaj qhov nce hauv lub ncauj tsev menyuam, subclavian, axillary thiab inguinal nodes. Qee zaum, cov qog nqaij hlav hauv plab tau cuam tshuam.
Cov pob txha thiab lub hauv nruab nrab lub paj hlwb raug cuam tshuam ntau dua, tab sis cov kab mob no hnyav dua. Sarcoidosis ntawm lub plawv tshwm sim nyob rau hauv 20-30% ntawm cov neeg mob thiab yog asymptomatic. Sab laug ntawm lub plawv txo qis hauv ntim, txoj cai ventricle nce.
Kev kuaj xyuas ntxov thiab kev kho mob ua rau muaj feem tau txais txiaj ntsig zoo. Hauv lwm qhov xwm txheej, kev hloov pauv hauv lub ntsws tshwm sim, uas thaum kawg ua rau kev tsis taus.
Löfgren's syndrome: ib qho mob sib txawv ntawm sarcoidosis
Sarcoidosis feem ntau tsis meej pem nrog tuberculosis vim qhov zoo sib xws ntawm cov tsos mob. Yuav tsum tau kuaj xyuas kom meej ntawm no, vim tias qhov ua rau thiab kev kho mob sib txawv. Tsis muaj teeb meem koj yuav tsum kho koj tus kheej li cas, tshwj xeeb tshaj yog noj tshuaj rau cov neeg mob tuberculosis, qhov no tuaj yeem ua rau tuag taus.
Löfgren's syndrome (ib qho piv txwv classic) yog thaum tus neeg mob muaj kev ntsuam xyuas txaus siab. Kev hloov ntawm daim tawv nqaij raug pom. Tej zaum yuav tshwm sim:
- papules thiab plaques;
- lupus pernio;
- keloid nti;
- infiltrates;
- erythema nodosum;
- SKD thiab SKB Beck's sarcoid;
- ntau qhov ntom ntom hauv cov ntaub so ntswg subcutaneous.
Diagnosis
Kev tshuaj xyuas cov neeg mob uas muaj tus mobLöfgren yog ua x-rays. Kev suav tomography yog siv los ua ib txoj kev qhia meej. Kev kuaj ntshav biochemical thiab dav dav tau ua tiav.
Lub hom phiaj ntawm kev kho mob yog txhawm rau txo cov txheej txheem inflammatory. Txoj kev zoo tshaj plaws yog kev siv corticosteroids rau rau lub hlis. Thaum lub cev tseem ceeb raug cuam tshuam, yuav tsum tau kho glucocorticosteroid hormone.
Cov chav kawm nrawm nrawm yog kho nrog cov kev kawm luv luv ntawm cov tshuaj tiv thaiv kab mob hauv cov hlab ntsha. Hauv cov xwm txheej uas kev kho tsis muaj zog, plasmapheresis (ntshav purification) yog ua. Nyob rau theem hnyav ntawm lub ntsws puas lawm, yuav tsum tau hloov lub cev. Cov chav kawm ntawm tus kab mob thiab cov txiaj ntsig ntawm kev kho mob feem ntau yog qhov zoo, koj tsuas yog xav tsis tau pib txheej txheem.
