Cov kws tshuaj niaj hnub muab cov neeg mob ntshav qab zib xaiv cov tshuaj insulin ntau. Thiab hnub no peb yuav tham txog yam tshuaj insulin yog dab tsi.
YInsulin: hom
Txhua qhov kev npaj cov tshuaj insulin tau muab faib ua peb hom (nyob ntawm lub sijhawm ua haujlwm thiab qhov pib ntawm cov txiaj ntsig kho):
- "luv";
- "medium";
- "long".
"Short" insulins
Cov insulins luv luv yog cov tshuaj ntau tshaj plaws rau cov neeg mob ntshav qab zib.
Tom qab cov khoom nkag mus rau tib neeg lub cev, nws pib ua haujlwm hauv peb caug feeb. Qhov no txhais nws mus rau hauv qeb ntawm cov tshuaj muaj txiaj ntsig zoo siv hauv kev kho mob ntshav qab zib. Feem ntau, hom tshuaj insulin no tau muab ib txhij nrog cov tshuaj insulin ntev ntev.
Txhawm rau xaiv, koj yuav tsum coj mus rau hauv tus account cov hauv qab no:
- tus neeg mob tus mob;
- qhov chaw txhaj tshuaj;
- dosage.
Kev npaj cov tshuaj insulin yog qhov nrov tshaj plaws, pib ua tiav thaum thawj zaug15 feeb tom qab kev tswj hwm. Cov no yog Apidra, Humagol thiab Novorapid.
Ntse
Ntawm cov tib neeg cov tshuaj insulins sai, nws tsim nyog hais txog kev npaj "Homorap" thiab "Insumad Rapid". Yeej tsis muaj qhov sib txawv ntawm lawv. Qhov sib txawv tsuas yog nyob rau hauv qhov seem ntawm cov amino acids nyob rau hauv nws muaj pes tsawg leeg.
"Fast" insulins ntawm tsiaj keeb kwm kuj suav nrog tshuaj "Insulrap SPP", "Iletin II Regular" thiab lwm yam. Lawv feem ntau raug tshuaj rau hom II mob ntshav qab zib. Txhais tau hais tias los ntawm pawg no muaj cov proteins uas muaj cov qauv sib txawv, thiab yog li tsis haum rau txhua tus neeg mob. Piv txwv li, tsiaj insulins "hloov" yuav tsum tsis txhob muab rau cov neeg uas lub cev tsis tuaj yeem ua cov lipids ntawm tsiaj.
Kev txais tos, ntau npaum, cia ntawm "luv" insulins
Noj tshuaj ua ntej noj mov. Hauv qhov no, nws yog cov khoom noj uas ua kom nrawm nrawm ntawm kev nqus ntawm insulin, cov nyhuv tshwm sim yuav luag tam sim.
"Fast" insulins tuaj yeem noj qhov ncauj, tom qab diluting lawv mus rau lub xeev ua kua.
Yog tias kev tswj hwm subcutaneous ntawm cov tshuaj tau xyaum, ces kev txhaj tshuaj yuav tsum tau ua li ntawm 30 feeb ua ntej noj mov.
Cov koob tshuaj rau txhua tus neeg mob ntshav qab zib yog xaiv tus kheej. Rau cov neeg laus, koob tshuaj yuav yog 8-24 units ib hnub, thiab rau cov menyuam yaus - tsis pub ntau tshaj 8 units.
Kua tshuaj ntawmQhov kub ntawm + 2- + 8 ° C. Lub txee hauv lub qhov rooj tub yees yog tsim rau qhov no.
Y "Average" insulins
Cov neeg mob ntshav qab zib raug yuam kom noj tshuaj kom tswj cov ntshav qab zib kom zoo. Tab sis txhua hom ntshav qab zib xav tau qee yam tshuaj insulin. Yog li, cov tshuaj uas muaj qhov nruab nrab ntev yog siv thaum cov piam thaj yuav tsum tau maj mam tawg. Nws kuj tseem siv tau yog tias "luv" insulin tsis muaj tam sim no.
Cov yam ntxwv ntawm "nruab nrab" insulins
Tshuaj muaj ntau yam nta:
- lawv pib ua hauv 10 feeb tom qab tswj hwm;
- Yuav siv sijhawm ntev rau cov khoom kom tawg tag.
Insulin nyob rau hauv pawg no yuav muaj lub hauv paus sib txawv, tshwj xeeb yog insulin zinc lossis isophane. Cov tshuaj hauv qab no tau ua pov thawj lawv tus kheej tshwj xeeb zoo:
- ntawm tib neeg cov insulins - Protafan, Humulin, Monotard thiab Homolong;
- ntawm cov khoom tsiaj yog cov tshuaj "Berlinsulin", "Monotard HM" thiab "Iletin II".
"Long" insulins
Nws yog lub sijhawm txhaj tshuaj uas tso cai rau cov neeg mob ntshav qab zib kom txaus siab rau lub neej yam tsis muaj kev tsis xis nyob los ntawm cov ntshav qab zib siab. Hom tshuaj insulin no txawv ntawm lwm tus li cas thiab hom tshuaj insulin ntev npaum li cas muaj nyob - txogwb tham txog.
Qhov sib txawv tseem ceeb ntawm cov tshuaj insulin hauv qhov no yog qhov kev ua ntawm cov tshuaj siv sijhawm ntev dua 24 teev.
Ntxiv rau, txhua hom insulin ua haujlwm ntev muaj cov tshuaj catalysts uas ua kom cov tshuaj ua haujlwm ntev. Lawv kuj ncua kev nqus cov suab thaj. Cov nyhuv kho tau tshwm sim tom qab li 4-6 teev, thiab lub sijhawm ua haujlwm tuaj yeem ncav cuag 36 teev.
insulins ntev ua haujlwm: hom twg muaj nyob
Cov tshuaj uas tau sau ntau tshaj plaws yog Determite thiab Glargine. Lawv qhov sib txawv tseem ceeb yog qhov txo qis hauv cov ntshav qab zib.
Ultratard, Ultralente-iletin-1, Huminsulin, Ultralong, thiab lwm yam kuj yog cov insulins ntev ntev
Cov tshuaj yog muab los ntawm tus kws kho mob, uas ntxiv pab kom tsis txhob muaj ntau yam teeb meem nyob rau hauv daim ntawv ntawm kev phiv.
Tshuaj siv thiab khaws cia
Insulin ntawm hom no tsuas yog siv tau los ntawm kev txhaj tshuaj. Tsuas yog tom qab nkag mus rau hauv lub cev hauv txoj kev no, nws pib ua haujlwm. Kev txhaj tshuaj yog muab tso rau hauv lub hauv pliaj, pob tw lossis ncej puab.
Ua ntej siv, lub raj mis yuav tsum tau shaken kom cov khoom sib xyaw hauv nws tau txais ib qho sib xws. Tom qab ntawd, nws yog npaj siv.
Khaws cov tshuaj raws li cov xwm txheej zoo ib yamluv luv acting insulins. Xws li kev tswj hwm kub tiv thaiv kev tsim ntawm flakes thiab granulation ntawm qhov sib tov, nrog rau cov tshuaj oxidation.
Txhaj tshuaj insulin ib zaug, qee zaum ob zaug ib hnub.
tshuaj insulin
qhov sib txawv ntawm insulin - tsis yog nyob rau lub sijhawm ua haujlwm nkaus xwb, tab sis kuj tseem nyob hauv keeb kwm. Tsiaj npaj thiab insulins zoo ib yam rau tib neeg raug cais tawm.
Pab npua thiab nyuj yog siv los muab tshuaj los ntawm thawj qeb. Cov txheej txheem lom neeg ntawm porcine-derived insulins suits tib neeg. Qhov txawv ntawm qhov no yog qhov tsis tseem ceeb - tsuas yog ib qho amino acid xwb.
Tab sis cov tshuaj zoo tshaj plaws yog, ntawm chav kawm, tib neeg insulins, uas yog siv ntau tshaj plaws. Kev tsim cov khoom tuaj yeem ua tau ob txoj hauv kev:
- thawj txoj hauv kev yog hloov ib qho amino acid tsis sib haum. Hauv qhov no, semi-synthetic insulin tau txais.
- Txoj kev thib ob ntawm kev tsim cov tshuaj muaj E. coli, muaj peev xwm ua kom cov protein ntau. Qhov no yuav yog tus neeg sawv cev biosynthetic.
Kev npaj zoo ib yam li tib neeg insulin muaj ntau qhov zoo:
- kom tau txais cov txiaj ntsig kho mob xav tau yuav tsum tau muab cov tshuaj me me;
- txhim kho lipodystrophy yog qhov tsawg;
- tshuaj tsis haum yog yuav luag tsis muaj.
Qib kev tu
Nyob ntawm qhov kev ua kom huv huvtshuaj muab faib ua:
- tsoos;
- monopic;
- monocomponent.
Cov tshuaj insulins ib txwm yog ntawm thawj qhov kev npaj tshuaj insulin. Lawv muaj nyob rau hauv lawv cov muaj pes tsawg leeg ntau yam ntawm cov protein impurities, uas tau los ua qhov ua rau muaj kev tsis haum tshuaj. Tam sim no, kev tsim cov tshuaj no tau txo qis.
Mono-peak insulin cov khoom lag luam muaj cov khoom tsis huv me me (hauv qhov txwv tsis pub siv). Tab sis monocomponent insulins yuav luag zoo tag nrho, vim tias qhov tsis tsim nyog impurities tseem tsawg dua qhov qis dua.
Qhov sib txawv tseem ceeb ntawm "luv" thiab "ntev" insulins
Y"Long" insulin | "Short" insulin | |
qhov chaw txhaj tshuaj | Txoj kev txhaj tshuaj yog muab tso rau hauv tus ncej puab, vim tias qhov no cov tshuaj nqus tau qeeb heev | Kev txhaj tshuaj yog muab tso rau hauv daim tawv nqaij ntawm lub plab, zoo li qhov no, insulin pib ua haujlwm yuav luag tam sim |
Tim sijhawm | Qhia tib lub sijhawm (sab sawv ntxov thiab yav tsaus ntuj). Ib txhij nrog koob tshuaj thaum sawv ntxov, txhaj tshuaj insulin luv luv yog muab | Noj tshuaj 20 - 30 feeb ua ntej noj mov |
Tshuaj rau pluas mov | "Long" insulin tsis cuam tshuam nrog kev noj zaub mov | Tom qab qhia cov tshuaj insulin luv luv, cov zaub mov yuav tsum tau noj yam tsis muaj kev poob. Yog tias qhov no tsis ua tiav, tom qab ntawd nws muaj peev xwm txhim kho hypoglycemia |
Raws li koj tuaj yeem pom, hom insulin (cov lus qhia kom meej qhov no)txawv ntawm qhov tseem ceeb. Thiab cov yam ntxwv no yuav tsum raug coj mus rau hauv tus account.
Peb tau tshuaj xyuas txhua hom tshuaj insulin thiab lawv cov txiaj ntsig ntawm tib neeg lub cev. Peb cia siab tias cov ntaub ntawv yuav pab tau. Noj qab nyob zoo!