Lub cev tib neeg yog tsim los ntawm ntau lab lub hlwb ntawm ntau yam duab, hom thiab ntau thiab tsawg. Lawv yog cov me me uas lawv tsuas tuaj yeem saib thiab kawm nyob rau hauv lub microscope. Qhov tseeb, cov hlwb yog cov khoom siv hauv microscopic los ntawm cov ntaub so ntswg, kab mob hauv nruab nrog cev thiab tag nrho lub cev tsim. Txawm hais tias qhov sib txawv ntawm cov duab, tag nrho cov hlwb yog tus cwj pwm los ntawm cov qauv txheej txheem. Lawv muaj ib tug txheej membrane, ib tug central nucleus, thiab ib tug semi-kua cytoplasm. Koj tuaj yeem tham txog ntau hom hlwb rau lub sijhawm ntev, tab sis hauv kab lus no tsuas yog ib hom, hu ua goblet cells, yuav raug txiav txim siab. Wb sim nkag siab tias lawv nyob qhov twg, lawv nyob qhov twg thiab lawv ua haujlwm li cas.
Variant npe
Cov hlwb no paub los ntawm ntau lub npe. Cov kab lus "goblet enterocyte", "goblet exocrinocide" thiab "goblet granulocyte" feem ntau yog siv. Hauv Latin, goblet cell hu ua enterocytus caliciformis. Lo lus "goblet cell" yog qee zaum siv, uas kuj yog hais txog goblet cell. Tag nrho cov ntsiab lus no sib npaug rau ib leeg thiab siv los ua cov lus sib piv.
Lub npe qhia txog qhov txawv txav ntawm cov hlwb. Lawv zoo li lub iav nqaim siab, nthuav me ntsis rau saum.
Cells ntawm noCov tsiaj muaj nyob rau hauv lub epithelium ntawm mucous daim nyias nyias thiab koom nyob rau hauv zus tau tej cov mucus. Lawv muaj nyob rau hauv lub cev ntawm tib neeg thiab tsiaj.
Localization. Lub plab
Lub goblet cell yog ib feem ntawm cov epithelium ntawm ntau lub cev tib neeg. Ib qho chaw ntawm localization yog cov hnyuv. Lub plab hnyuv epithelium muaj ib tug complex qauv. Nws ua ke ntau hom enterocytes, suav nrog ciam teb, goblet, acidophilic, tsis muaj ciam teb, endocrine, undifferentiated thiab lwm yam. Tag nrho cov ntawm lawv yog cov qog unicellular nrog cov haujlwm sib txawv. Yog li, piv txwv li, ciam teb hlwb ntawm lub epithelium koom nrog parietal digestion thiab nqus. Goblet hlwb yog lub luag haujlwm rau kev tsim cov hnoos qeev (peb yuav tham txog qhov no hauv cov ntsiab lus hauv qab no). Cov hlwb endocrine tsim cov tshuaj hormones hauv txoj hnyuv, thiab Pannet's acidophilic cells tsim ntau cov enzymes digestive. Kev ua haujlwm ntawm cov hlwb tsis zoo yog qhov rov tsim dua ntawm cov epithelium.
Cov kab mob hauv plab hnyuv muaj nyob rau ntawm txoj hnyuv villi. Lawv yog embedded ib tug ntawm ib lub sij hawm ntawm ciam teb hlwb. Ntawm qhov chaw apical ntawm lub villi thiab hauv cov tubular kev nyuaj siab ntawm cov mucous daim nyias nyias, hu ua Lieberkühn cov qog los yog plab hnyuv crypts, goblet hlwb tsis pom. Txawm hais tias muaj qee qhov tshwj xeeb.
Muaj ntau lub hlwb ntawm hom no hauv cov hnyuv. 9.5% ntawm enterocytes yog goblet hlwb ntawm lub epithelium. Ntxiv mus, lawv tus naj npawb nce nyob rau hauv cov kev taw qhia distal ntawm txoj hnyuv. Lawv sib npaug faib rau sab sauv ntawm cov crypts thiab lub hauv paus ntawm villi, ntawm villi lawv tus kheej yog qhov tseem ceeb.tsawg.
Airways
Lwm qhov chaw ntawm qhov chaw ntawm goblet exocrinocytes yog cov kab mob ua pa. Ntawm no, yuav luag 30% ntawm cov epithelium muaj cov cell. Cells kuj tau npaj ib leeg. Lawv muaj vacuoles uas muaj mucous secretion. Vacuoles nyob ntawm qhov nthuav dav apical. Qhov nqaim ntawm lub cell muaj cov Golgi complex thiab ntau mitochondria. Lub goblet cell ntawm txoj kev ua pa yog nruab nrog microvilli, uas pom ntau dua tom qab tso tawm cov hnoos qeev.
Cov kua paug tawm ntawm cov hnoos qeev yog cyclical, nyob ntawm lwm yam, piv txwv li kub thiab av noo.
Goblet cells of the conjunctiva
Qhov chaw tom ntej ntawm goblet hlwb yog lub qhov muag ntawm qhov muag. Muaj ntau ntau ntawm lawv nyob rau hauv lub conjunctival mucosa. Cov zais zais zais los ntawm cov hlwb no txawv ntawm cov hnoos qeev zais los ntawm cov epithelium hauv lwm cov kabmob. Goblet hlwb ntawm lub conjunctiva yog nyob rau ntawm lub basal txheej thiab muaj ib tug oval thiab puag ncig. Cov mucus uas lawv synthesize thiab secrete khi rau hauv ib hom network uas captures thiab kho txawv teb chaws lub cev thiab cov kab mob. Thaum lub ntsais muag, lub vas tawg thiab hloov mus rau ntawm ntug nruab nrab, tshem cov khib nyiab thiab cov kab mob ntawm lub qhov muag.
Pancreas goblet cells
Goblet cells muaj nyob rau hauv cov ducts excretory ntawm pancreas. Lawv nyob tsis raws tag nrho qhov ntev ntawm cov ducts, tab sis nyob rau hauv lawv qhov dav. Ntawm no, cov qog exocrine tsim cov kab mob mucosal.
Parotid salivary qog
Kab qaub ncaugkuj nplua nuj hauv goblet hlwb. Lawv nyob ze ntawm lub qhov ncauj thiab tso cov hnoos qeev uas tuaj yeem ua rau muaj tshuaj tiv thaiv kab mob microbes. Nrog rau hnub nyoog, tus naj npawb ntawm goblet hlwb nyob rau hauv parotid salivary qog txo. Antimicrobial barrier tsis muaj zog.
cov lus qhia ua haujlwm
Goblet cells tsim cov mucus insoluble hu ua mucin. Mucin kab cov mucous daim nyias nyias, qee zaum accumulating mus rau ib tug tuab ntawm 1.5 hli. Txhawm rau tsim nws, cov mucitogenic granules nqus dej thiab o. Goblet cell mucus muaj ntau txoj haujlwm. Nyob rau hauv lub plab, pancreas thiab txoj hnyuv, nws moisturizes mucous daim nyias nyias, txhawb cov ntsiab lus ntawm lub plab thiab cov hnyuv, thiab yog ib feem ntawm cov txheej txheem ntawm parietal digestion. Nyob rau hauv lub conjunctiva, ntxiv rau moisturizing, nws muaj kev tiv thaiv muaj nuj nqi, nyob rau hauv cov qaub ncaug qog nws muaj ib tug barrier muaj nuj nqi.
Goblet cell antibodies
Nyob hauv lub xeev ib txwm, tsis muaj cov tshuaj tiv thaiv kab mob rau goblet hlwb hauv cov ntshav. Yog tias cov tshuaj tiv thaiv no raug kuaj pom thaum kuaj ntshav los ntawm cov hlab ntsha, ces tus neeg mob muaj ulcerative colitis. Yog li ntawd, kev kuaj goblet cell antibody yog qhia rau kev kuaj mob sib txawv ntawm cov kab mob plab hnyuv loj.
