Keratolytic cov neeg ua haujlwm pab khaws cov kev zoo nkauj thiab cov hluas ntawm daim tawv nqaij lossis kho cov epidermis los ntawm cov tawv nqaij mob nrog cov txheej txheem ntawm hyperkeratosis. Nws paub tias txhua hnub rov ua dua tshiab ntawm daim tawv nqaij yog txuam nrog kev tuag ntawm ntau lab ntawm cov hlwb ntawm nws qhov chaw, qhov tsub zuj zuj ntawm cov uas ua rau keratinization ntawm cov epidermis, tsis sib xws thiab dull complexion, tev, nplua wrinkles thiab clogged pores. Tsis tu ncua exfoliation ntawm nplai nkoos lub regeneration ntawm lub epidermis, muab ib tug noj qab nyob zoo saib thiab qab ntxiag velvety. Nyob rau hauv rooj plaub thaum, vim muaj ntau yam kab mob, cov txheej txheem ntawm kev tsis lees paub ntawm cov hlwb tuag raug cuam tshuam, hyperkeratosis tsim - ntau keratinization. Qhov tshwm sim no tuaj yeem muaj ob qho tib si hauv zos (hauv qee thaj chaw) thiab ib qho dav dav (thoob plaws hauv lub cev).
Keratolytics yog dab tsi?
Nws yog sab nraum zoovcov tshuaj siv rau kev kho kom zoo nkauj thiab kho mob. Lo lus no los ntawm kev sib koom ua ke ntawm ob lo lus: "keratin" - lub ntsiab lus ntawm cov protein uas tsim cov kab mob epidermis (xws li calluses thiab pob kws), plaub hau thiab rau tes, thiab "lysis", lub ntsiab lus "kev puas tsuaj thiab lwj." Los ntawm kev rhuav tshem cov qauv ntawm keratin, cov tshuaj keratolytic muaj peev xwm ua kom mos, yaj thiab pab txhawb kev tsis lees paub ntawm stratum corneum ntawm qhov chaw ntawm cov epidermis, ntsia thawv daim hlau thiab cov plaub hau, thiab muaj peev xwm kho tau ntau yam kab mob ntawm daim tawv nqaij. Keratolytics nrog qis concentration muaj qhov cuam tshuam me ntsis thiab ua haujlwm zoo nrog ntau yam tsis xws luag. Cov tshuaj keratolytic niaj hnub no muaj nyob rau hauv daim ntawv ntawm cov tshuaj pleev, thaj ua rau thaj, hmoov, kua roj vanish, collodions, kev daws teeb meem thiab pastes. Nyob rau hauv cosmetology, exfoliants, depilatory cream thiab lwm yam khoom rau ilv tev uas muaj acids nyob rau hauv lawv muaj pes tsawg leeg muaj ib tug zoo xws li, tab sis tsawg concentrated nyhuv.
Npe ntawm cov khoom uas tshem tawm cov stratum corneum
Keratolytic kev ua haujlwm muaj cov kua qaub: salicylic (hauv qhov siab ntawm 5 txog 60%), lactic (los ntawm 10 txog 20%), benzoic (los ntawm 5 mus rau 15%), trichloroacetic (10%), pyrrogallic (los ntawm 10). rau 20%), nrog rau urea (los ntawm 10 mus rau 50%), resorcinol (los ntawm 10 mus rau 20%), potassium iodide (50%), barium sulfide (15%), thymol thiab phenol (5%). Cov keratolytic cov neeg ua haujlwm no ua haujlwm ua haujlwm ntawm thaj ua rau thaj, kua roj vanish, tshuaj pleev (feem ntau siv hauv compresses lossis occlusive hnav khaub ncaws), tsawg zaus hauv pastes thiabkev daws teeb meem.
Kev siv tshuaj keratolytic
Cov lus qhia rau kev sau tshuaj rau pawg no yog:
- Hyperkeratosis, tshwj xeeb tshaj yog palmar-plantar localization - psoriasis, tylotic eczema, fungal kab mob thiab calluses.
- Onychomycosis, uas softening thiab tshem tawm cov fungus cuam tshuam rau ntsia thawv phaj yog qhov tsim nyog.
- Cov kab mob ntawm daim tawv nqaij yuav tsum tau ua cov txheej txheem exfoliating - dermatoses nrog cov yam ntxwv ntau dhau ntawm keratinized epithelial hlwb nyob rau hauv cov cheeb tsam cuam tshuam (psoriasis, erythroderma, mob eczema, qee hom toxicoderma, zoo li hyper- thiab parakeratosis hauv cov tsos mob). Nyob rau hauv cov ntaub ntawv no, salicylic acid, naftalan los yog tar ntawm tsawg concentration (tsis ntau tshaj 3-5%) yog siv raws li ib feem ntawm cov tshuaj pleev tshwj xeeb, cream thiab emulsions nrog emollients thiab oily vitamins A thiab E, uas normalizes txheej txheem ntawm cell regeneration.
- Hyperpigmentation (ntau dua ntawm lub ntsej muag) qhov twg keratolytics tau ua ke nrog cov tshuaj bleaching.
me ntsis peels thiab lawv cov concentration
Tsis zoo li cov tshuaj txhuam hniav uas khawb ntawm daim tawv nqaij, cov khoom keratolytic soften thiab loosen stratum corneum, yaj nws, uas nyiam nws qhov kev tsis lees paub. "Squamolytic nyhuv" (exfoliation) xyuas kom tshem tawm cov horny ntau dhau los ntawm cov teeb meem ntawm daim tawv nqaij (tshwj xeeb los ntawm pob txuv lossis psoriasis), los ntawm cov ntsaws ruaj ruaj ntawm calluses thiab pob kws, plaub hau - nrog hypertrichosis, nrog rau kev tsis lees paub.deformed ntsia thawv phaj. Cov nyhuv keratolytic ntawm pawg tshuaj no tau tshwm sim thaum cov txheej txheem tshuaj (acid) tev tawm. Nyob rau hauv siab concentration, lawv yog siv los ntawm cov kws tshaj lij. Acid exfoliants ntawm qis saturation muaj ib tug superficial exfoliating nyhuv, thiab nyob rau hauv me me koob tshuaj - ib tug keratoplastic nyhuv, uas yog, restores lub ntuj txheej txheem ntawm tsim ntawm lub stratum corneum.
Pharmacodermatology hauv kev tawm tsam ntau dhau keratinization ntawm dermis
Nyob rau hauv cov ntaub ntawv me me ntawm pob txuv lossis mob hnyav ntawm tus kab mob, salicylic acid thiab kev npaj raws li nws muaj cov txiaj ntsig zoo tshaj plaws: hmoov uas muaj 2-5% ntawm cov tshuaj nquag, pastes thiab tshuaj pleev nrog rau qhov concentration ntawm 1. -10% thiab haus cawv rau kev siv hauv tsev (tsis pub ntau tshaj 1-2%).
Aromatic retinoids tuaj yeem siv los kho pob txuv loj. Cov thawj coj ntawm cov nyiaj hauv pab pawg no yog "Differin" (gel, cream) lossis "Isotretinoin", thiab "Roaccutane".
Rau cov kev kho mob ntawm cov ntaub ntawv nyuaj ntawm pob txuv, dermatologists sau cov tshuaj keratolytic, cov npe uas tau paub dav hauv pharmacodermatology:
- Baziron AS.
- Neotigazon.
- Akriderm SK.
- Vipsogal.
- "Belosalik".
- Tretinoin (Airol).
- Diprosalik
- YBensalitin.
- Lorinden A.
- YCarboderm.
Cov tshuaj no muaj, ntxiv rau keratolytic, tiv thaiv kab mobcov khoom, uas muaj cov txiaj ntsig zoo ntawm qhov tshwm sim hauv kev kho pob txuv. Rau psoriasis, hyperkeratosis thiab lwm yam kab mob ntawm daim tawv nqaij, ob qho tib si cov npe tshuaj keratolytic thiab Betadermik, Betnovate S, Keratolan, Lokasalen, Elokom S thiab Kerasal tuaj yeem siv rau hauv txoj kev kho mob. Cov tshuaj pleev no yog cov tshuaj uas tsis yog-steroidal anti-inflammatory siv rau sab nraud. Cov tshuaj no kuj raug sau tseg rau eczema, ichthyosis, oily seborrhea thiab hyperhidrosis (tawm hws ntau dhau).
Keratolytics muaj txiaj ntsig zoo rau txhua qhov kev mob ntawm daim tawv nqaij thiab kis kab mob, thaum muaj cov pob kws, pob kws, pob kws, hlawv thiab hyperpigmentation. Cosmetologists feem ntau pom zoo kom npaj raws li glycolic acid nyob rau hauv ib tug concentration ntawm 10-20% rau kev kho mob, tab sis lawv tau muab tshuaj nyob rau hauv ib tug tib neeg lub hauv paus los daws qhov teeb meem aesthetic.
Keratolytics rau pob kws thiab calluses
Ntev hnav ntawm cov poj niam khau nrog heels siab thiab lwm yam khau tsis xis nyob provokes ntau keratinization ntawm daim tawv nqaij ntawm ko taw. Qhov yuav tsum tau tshem ntawm pob kws thiab cov calluses qhuav - cov kev mob tshwm sim ntawm daim tawv nqaij uas tau tshwm sim vim kev ua haujlwm ntawm cov tawv nqaij thiab lub siab ntawm ko taw - cuam tshuam nrog kev siv cov tshuaj uas muaj txiaj ntsig Ph (qhov taw qhia ntawm cov ntsiab lus acid. nyob rau hauv ib yam khoom).
Alkalis thiab acids yog cov khoom tseem ceeb uas rhuav tshem cov stratum corneum. Raws li lawv, cov tshuaj keratolytic rau pob kws yog tsim:
- kho-thiab-prophylactic ko taw "5 hnub";
- creams "Namosol 911" (raws li tshuaj yej tsob ntoo extract), "Super Antimozolin" (raws li lactic acid) thiab "Green Planet" (nrog lactic acid thiab roj);
- zoo tab sis kim Norwegian urea cream Neutrogena, TianDe (nrog nab rog);
- kho-thiab-prophylactic tincture rau pedicure Gehwol;
- cream "Healer" (nrog kho urea);
- Bensalitin tshuaj pleev (raws li benzoic thiab salicylic acids);
- tshuaj tsis muaj xim rau kev siv sab nraud "Kollomac" (cov khoom tseem ceeb yog salicylic thiab lactic acids ua ke nrog polidocanol).
Keratolytic tshuaj rau pob kws - cov no yog cov tshuaj saum toj no uas ua haujlwm zoo nrog pob kws, thiab tshuaj pleev raws li salicylic acid, thiab pob kws kua (xws li dej cawv), thiab Crown ntawm Siberia cream (nrog tshuaj tua kab mob), thiab ntau ntxiv.
Keratoplastic tshuaj kho rau pob kws
Compeed zoo thaj ua rau thaj txo cov kev ua haujlwm ntawm daim tawv nqaij, txo qhov mob thiab siv tau ob peb hnub kom txog thaum cov pob kws softens thiab tawm. Lwm qhov sib npaug zoo-paub tshuaj rau pob kws yog Suav pob kws thaj "Shuyangsuan". Cov daim hlau liab no nrog cov khoom siv ua haujlwm yog glued rau cov tawv nqaij thiab qhuav. Siv lawv tsawg kawg rau hnub. Lub thaj "Salipod" nrog tshuaj tua kab mob thiab tshuaj tua kab mob muaj salicylic acid, sulfur, uas ua rau daim tawv nqaij qhuav, yog pasted.callus thiab kav ob hnub. Tom qab plaub daim ntawv thov, raws li txoj cai, keratinization softens thiab ploj mus. Urgo's keratolytic thaj yog tsim los ntawm cov noob nplej roj thiab tuaj nyob rau hauv ob hom: pob kws thaj thiab ib qho kev tiv thaiv ib txwm.
Keratolytics rau qhov zoo pedicure: ua cov phaj
rau tes tuaj yeem ua rau cov neeg mob ntshav qab zib, psoriasis, eczema, lichen planus thiab lwm yam tawv nqaij. Tsis tas li ntawd nyob rau hauv daim hlau tej zaum kuj muaj tej thaj chaw uas cuam tshuam los ntawm fungus, kab mob los yog kab mob. Ib txoj hauv kev los tshem tawm cov phaj deformed yog tshuaj, thaum keratolytic ntsia thawv khoom siv rau lawv qhov chaw horny thiab dissolve qhov tsis xws luag. Cov khoom zoo li no tau muaj los ntawm thaj ua rau thaj nrog cov concentration ntawm 20 mus rau 50% urea thiab onycholysin hmoov, uas muaj 15% barium sulfide (hauv talc). Piv txwv li, hauv kev npaj ua ke "Mycospor" (cov tshuaj pleev) muaj 40% urea thiab 1% ntawm cov tshuaj tiv thaiv kab mob - bifonazole. Cov tshuaj no yog tsim los ntawm Bayer (Lub teb chaws Yelemees) nyob rau hauv daim ntawv ntawm ib tug qab zib, tov thiab ib tug tshwj xeeb cov khoom siv rau kev kho mob ntawm tes nrog tib lub concentration ntawm cov active ingredient.
Txhua qhov kev npaj ntawm pab pawg no muaj cov khoom xyaw keratolytic (urea thiab salicylic acid nyob rau hauv siab), ib qho tshuaj tua kab mob (bifonazole lossis ketoconazole) thiab tshuaj tua kab mob (quinosol lossis iodine). Fixation ntawm tus ntsia thawv phaj ntawm ib qho yooj yim los yog complex lead thaj, Ureaplast, trichloroacetic (CCL3COOH),salicylic los yog xab npum-salicylic thaj yuav ua rau kom muaj kev puas tsuaj ntawm qhov chaw tsis raug ntawm cov ntsia hlau, uas yuav tsum tau ua ntu zus thiab ntxuav.
