NSAID abbreviation - Qhov ntawd txhais li cas rau koj? Yog tias tsis yog, peb xav kom nthuav dav koj lub qab ntug me ntsis thiab nrhiav seb cov ntawv tsis paub zoo li cas no sawv cev rau. Nyeem tsab xov xwm - thiab txhua yam yuav ua kom meej meej. Peb cia siab tias nws yuav tsis tsuas yog qhia, tab sis kuj nthuav!
NSAIDs - transcript
Cia peb cov neeg nyeem tsis paub txog lub sijhawm ntev. NSAIDs sawv cev rau cov tshuaj uas tsis yog-steroidal anti-inflammatory - cov tshuaj nyob rau hauv peb lub sij hawm yog heev nrov thiab nrov, vim hais tias lawv muaj peev xwm mus ib txhij tshem tawm qhov mob thiab txo qhov mob ntawm ntau yam kabmob ntawm peb lub cev. Yog tias txog tam sim no koj tsis tau muaj qhov xav tau noj NSAIDs - qhov no tuaj yeem suav tias yuav luag yog qhov txuj ci tseem ceeb. Koj yog ib tug uas tsis tshua muaj hmoo, tiag tiag, koj txoj kev noj qab haus huv yuav tsum khib!
Peb ua ntej ntawm cov lus nug tom ntej thiab tam sim ntawd qhia koj txog kev txiav txim siab ntawm lo lus "non-steroidal". Qhov no txhais tau hais tias cov tshuaj no tsis yog hormonal, i. tsis muaj cov tshuaj hormones. Thiab qhov no yog qhov zoo heev, vim txhua tus paub tias cov tshuaj hormonal tsis tuaj yeem tshwm sim thiab txaus ntshai npaum li cas.
MuajNSAIDs nrov
Yog tias koj xav tias NSAIDs yog cov tshuaj uas nws lub npe tsis tshua tau hais hauv lub neej niaj hnub, ces koj yuam kev. Ntau tus neeg tsis paub txawm tias ntau npaum li cas peb yuav tsum siv cov tshuaj uas tsis yog tshuaj steroidal los kho ntau yam kab mob uas tau nrog tib neeg txij li lub sijhawm uas Adas thiab Eva raug ntiab tawm ntawm lub vaj kaj siab. Nyeem cov npe ntawm cov kev kho mob zoo li no, kom paub tseeb tias qee qhov ntawm lawv nyob hauv koj lub tsev pab thawj zaug. Yog li, NSAIDs suav nrog tshuaj xws li:
- "Aspirin".
- "Amidopyrine".
- "Analgin".
- Y"Piroxicam".
- "Quickgel".
- Y"Diclofenac".
- Ketoprofen
- "Indomethacin".
- "Naproxen".
- "Ketorolac".
- Y"Flurbiprofen".
- "Voltarengel".
- "Nimesil".
- Y"Diclofenac".
- Ibuprofen
- "Indopan".
- "Ipren".
- "Upsarin UPSA".
- "Ketanov".
- "Mesulide".
- "Movalis".
- "Nise".
- "Nurofen".
- "Ortofen".
- "Trombo ACC".
- Y"Ultrafen".
- "Fastum".
- "Finalgel".
Ketorol Ketorol
Yog, lawv yog NSAIDs tag nrho. Cov npe tau dhau los ua ntev, tab sis, ntawm chav kawm, deb ntawm kev ua tiav. Thiab tseem nwsmuab ib lub tswv yim ntawm ntau yam niaj hnub uas tsis yog-steroidal anti-inflammatory tshuaj.
Qee keeb kwm tseeb
Thawj NSAIDs thawj zaug tau paub rau tib neeg thaum ub. Piv txwv li, nyob rau tim lyiv teb chaws thaum ub, willow bark, ib tug natural qhov chaw ntawm salicylates thiab ib tug ntawm cov thawj non-steroidal anti-inflammatory tshuaj, tau dav siv los txo kub taub hau thiab mob. Thiab txawm tias nyob rau lub sijhawm nyob deb, cov kws kho mob tau kho lawv cov neeg mob los ntawm kev mob sib koom tes thiab ua npaws nrog decoctions ntawm myrtle thiab txiv qaub balm - lawv kuj muaj salicylic acid.
Nyob rau hauv nruab nrab ntawm lub xyoo pua 19th, chemistry pib tsim sai heev, uas ua rau lub zog rau kev loj hlob ntawm pharmacology. Nyob rau tib lub sijhawm, thawj cov kev tshawb fawb ntawm cov tshuaj ntawm cov tshuaj tau los ntawm cov ntaub ntawv cog tau pib ua. Ntshiab salicin los ntawm willow bark yog synthesized nyob rau hauv 1828 - nws yog thawj kauj ruam ntawm tsim kom paub "Aspirin" rau peb txhua tus.
Tab sis nws yuav siv sijhawm ntau xyoo ntawm kev tshawb fawb ua ntej cov tshuaj no yug. Ib qho xwm txheej loj tau tshwm sim hauv xyoo 1899. Cov kws kho mob thiab lawv cov neeg mob tau txais txiaj ntsig sai sai rau cov txiaj ntsig ntawm cov tshuaj tshiab. Xyoo 1925, thaum muaj tus mob khaub thuas txaus ntshai kis mus rau Tebchaws Europe, Aspirin tau los ua tus cawm seej rau ntau tus neeg. Thiab nyob rau xyoo 1950, cov tshuaj uas tsis yog-steroidal anti-inflammatory siv tau ntaus Guinness Phau Ntawv Cov Ntaub Ntawv raws li cov tshuaj loog nrog cov khoom muag loj tshaj plaws. Zoo, tom qab kws muag tshuaj tau tsim lwm yam uas tsis yog-steroidal anti-inflammatorytshuaj (NSAIDs).
Rau cov kab mob dab tsi yog cov tshuaj tsis-steroidal tshuaj tiv thaiv kab mob siv
Qhov ntau ntawm NSAIDs yog qhov dav heev. Lawv muaj txiaj ntsig zoo hauv kev kho mob ntawm ob qho tib si mob thiab mob ntev nrog mob thiab mob. Niaj hnub no, kev tshawb fawb yog nyob rau hauv tag nrho viav vias los kawm txog cov txiaj ntsig ntawm cov tshuaj no hauv kev kho mob ntawm cov kab mob plawv thiab cov hlab ntsha. Thiab niaj hnub no yuav luag txhua tus paub tias lawv tuaj yeem siv rau qhov mob ntawm tus txha caj qaum (NSAIDs rau osteochondrosis yog kev cawmdim tiag tiag).
Ntawm no yog ib daim ntawv teev cov kab mob uas siv ntau yam uas tsis yog-steroidal tshuaj tiv thaiv kab mob:
- Fever.
- Headaches, migraines.
- Rheumatoid mob caj dab.
- Gout.
- Arthrosis.
- Osteoarthritis.
- Dysmenorrhea.
- mob arthropathies (psoriatic mob caj dab, ankylosing spondylitis, Reiter's syndrome).
- Postoperative mob syndrome.
- mob me me mus rau nruab nrab nrog kev raug mob thiab ntau yam kev hloov pauv.
Kev faib tawm ntawm NSAIDs los ntawm lawv cov qauv tshuaj
Nyeem cov kab lus no, koj twb muaj sijhawm los xyuas kom meej tias muaj ntau cov tshuaj uas tsis yog tshuaj steroidal. Txhawm rau taug qab ntawm lawv yam tsawg kawg me ntsis zoo dua, cia peb faib cov nyiaj no. Ua ntej tshaj plaws, lawv tuaj yeem muab faib ua cov hauv qab no: ib pawg - acids thiab ib pawg NSAIDs - tsis yog-acid.derivatives.
thawj yog:
- Salicylates (koj tuaj yeem xav txog "Aspirin" tam sim ntawd).
- Phenylacetic acid derivatives ("Aceclofenac", "Diclofenac", thiab lwm yam).
- Pyrazolidines (metamisole sodium, paub rau peb feem ntau yog "Analgin", "Phenylbutazone, thiab lwm yam).
- Oxicams ("Tenoxicam", "Meloxicam", "Piroxicam", "Tenoxicam").
- Derivatives ntawm indoleacetic acid ("Sulindak", "Indomethacin", thiab lwm yam).
- Derivatives ntawm propionic acid ("Ibuprofen", thiab lwm yam).
Pab pawg thib ob yog:
- Sulfonamide derivatives ("Celecoxib", "Nimesulide", "Rofecoxib").
- Alkanones ("Nabumetone").
Kev faib tawm ntawm cov tshuaj tsis-steroidal tshuaj tiv thaiv kab mob los ntawm lawv cov txiaj ntsig
Kev siv NSAIDs hauv osteochondrosis thiab kho lwm yam kab mob sib koom ua ke tuaj yeem ua haujlwm zoo. Tab sis, hmoov tsis, tsis yog txhua yam tshuaj muaj tib yam hauv lawv cov txiaj ntsig. Cov thawj coj tsis sib cav ntawm lawv tuaj yeem txiav txim siab:
- Y"Diclofenac".
- Ketoprofen
- "Indomethacin".
- Y"Flurbiprofen".
- "Ibuprofen" thiab lwm yam tshuaj.
Cov tshuaj teev npe hu ua yooj yim; piv txwv li, ntawm lawv lub hauv paus, NSAIDs tshiab tuaj yeem tsim thiab xa mus rau lub tsev muag tshuaj, tab sis nyob rau hauv ib lub npe txawv thiab feem ntau ntawm tus nqi siab dua. Txhawm rau kom tsis txhob nkim koj cov nyiaj, ua tib zoo kawm tshooj tom ntej. Cov ntaub ntawv muaj nyob hauv nws yuav pab koj xaiv qhov yog.
Yuav nrhiav dab tsi thaum xaiv tshuaj
NSAIDs yog, feem ntau, cov tshuaj niaj hnub zoo heev, tab sis thaum koj tuaj rau lub tsev muag tshuaj, nws yog qhov zoo dua kom paub txog qee qhov nuances. Dab tsi? Nyeem ntxiv!
Piv txwv li, koj muaj kev xaiv ntawm qhov zoo dua los yuav: "Diclofenac", "Ortofen" lossis "Voltaren". Thiab koj tab tom sim nug tus kws muag tshuaj uas cov tshuaj no zoo dua. Feem ntau yuav, koj yuav raug qhia tus nqi kim dua. Tab sis qhov tseeb yog tias muaj pes tsawg leeg ntawm cov tshuaj no yuav luag zoo tib yam. Thiab qhov sib txawv ntawm cov npe tau piav qhia los ntawm qhov tseeb tias lawv tau tsim los ntawm cov tuam txhab sib txawv, uas yog vim li cas cov npe txawv ntawm ib leeg. Tib yam tuaj yeem hais tau, piv txwv li, txog "Metindol" thiab "Indomethacin" lossis "Ibuprofen" thiab "Brufen", thiab lwm yam.
txhawm rau txheeb xyuas qhov tsis meej pem, yuav tsum ua tib zoo saib ntawm lub ntim, vim tias cov khoom xyaw tseem ceeb ntawm cov tshuaj yuav tsum tau qhia rau ntawd. Tsuas yog nws yuav sau, feem ntau yuav, ua ntawv me.
Tab sis tsis yog tag nrho. Qhov tseeb, nws tsis yooj yim li ntawd! Kev siv NSAID analogue ntawm qee cov tshuaj uas koj paub txog yuav ua rau muaj kev tsis haum tshuaj lossis kev phiv uas koj tsis tau ntsib dua ua ntej. Qhov teeb meem no yog dab tsi? Yog vim li cas tej zaum yuav dag nyob rau hauv ntxiv additives, uas, ntawm chav kawm, tsis muaj dab tsi tau sau nyob rau hauv lub ntim. Yog li koj yuav tsum kawmcov lus qhia.
Lwm qhov laj thawj rau qhov sib txawv ntawm cov tshuaj analogue yog qhov sib txawv ntawm qhov ntau npaum li cas. Cov neeg tsis paub lus feem ntau tsis xyuam xim rau qhov no, tab sis nyob rau hauv vain. Tom qab tag nrho, cov ntsiav tshuaj me tuaj yeem muaj "nees" koob tshuaj ntawm cov tshuaj nquag. Hloov pauv, cov tshuaj loj loj lossis cov tshuaj ntsiav tshwm sim ntau npaum li 90 feem pua tau sau.
Qee lub sij hawm cov tshuaj kuj tsim nyob rau hauv daim ntawv retarded, uas yog, raws li ntev-acting (ntev) tshuaj. Ib qho tseem ceeb ntawm cov tshuaj no yog lub peev xwm yuav nqus tau maj mam, kom lawv qhov kev ua tau zoo nyob rau ib hnub. Xws li cov tshuaj tsis tas yuav qaug cawv 3 lossis 4 zaug hauv ib hnub, ib koob tshuaj yuav txaus. Cov yam ntxwv ntawm cov tshuaj no yuav tsum tau qhia rau ntawm pob lossis ncaj qha rau hauv lub npe. Piv txwv li, "Voltaren" nyob rau hauv daim ntawv ntev yog hu ua "Voltaren-retard".
Daim npe ntawm cov tshuaj analogues paub
Peb tshaj tawm daim ntawv qhia me me no hauv kev cia siab tias nws yuav pab koj taug qab ntau lub khw muag tshuaj zoo nkauj. Cia peb hais tias koj tam sim ntawd xav tau NSAIDs zoo rau arthrosis los txo qhov mob hnyav. Koj muab daim ntawv khib nyiab thiab nyeem cov npe hauv qab no:
- Analogues ntawm "Diclofenac", ntxiv rau cov uas twb tau hais lawm "Voltaren" thiab "Ortofen", kuj yog "Diclofen", "Dicloran", "Diclonac", "Rapten", "Diclobene", "Artrozan ","Naklofen".
- Indomethacin yog muag raws li hom xws li Indomin, Indotard, Metindol, Rheumatin, Indobene, Inteban.
- Analogues ntawm "Piroxicam": "Erazon", "Piroks", "Roxicam", "Pirocam".
- Analogues ntawm "Ketoprofen": "Flexen", "Profenid", "Ketonal", "Artrosilen", "Knavon"
- Qhov nrov thiab pheej yig "Ibuprofen" muaj nyob rau hauv cov tshuaj xws li Nurofen, Reumafen, Brufen, Bolinet.
Txoj cai rau noj NSAIDs
Kev siv NSAIDs tuaj yeem nrog ntau yam kev mob tshwm sim, yog li nws pom zoo kom koj ua raws li cov cai no thaum noj lawv:
1. Kev paub txog cov lus qhia thiab ua raws li cov lus pom zoo hauv nws yog qhov yuav tsum tau ua!
2. Thaum noj tshuaj ntsiav lossis ntsiav tshuaj los ntawm qhov ncauj, nqa nrog ib khob dej los tiv thaiv koj lub plab. Txoj cai no yuav tsum tau ua raws li txawm tias koj haus cov tshuaj niaj hnub no (uas suav tias muaj kev nyab xeeb dua), vim tias kev ceev faj ntxiv yeej tsis mob;
3. Tsis txhob pw tom qab noj tshuaj li ib nrab teev. Qhov tseeb yog tias lub ntiajteb txawj nqus yuav ua rau muaj kev zoo dua ntawm cov tshuaj ntsiav hauv txoj hlab pas;
4. Nws yog qhov zoo dua los tsis kam haus cawv, vim tias kev sib xyaw NSAIDs thiab cawv yog qhov sib xyaw ua ke uas tuaj yeem ua rau ntau yam kab mob plab.
5. Ib hnub tsis tsim nyognoj ob yam tshuaj uas tsis yog tshuaj steroidal yuav tsis nce qhov txiaj ntsig zoo, tab sis feem ntau yuav ntxiv cov kev mob tshwm sim.
6. Yog tias cov tshuaj tsis pab, nrog koj tus kws kho mob tham, tej zaum koj yuav raug muab tshuaj tsawg dhau lawm.
Cov teebmeem thiab nonsteroidal gastropathy
Tam sim no koj yuav tsum paub seb NSAID gastropathy yog dab tsi. Hmoov tsis zoo, tag nrho cov NSAIDs muaj kev phiv loj heev. Lawv muaj qhov tshwj xeeb tsis zoo rau lub plab zom mov. Cov neeg mob tuaj yeem cuam tshuam los ntawm cov tsos mob xws li
- Ntaus (qee zaum phem heev).
- Vim.
- Dyspepsia.
- plab hnyuv los ntshav.
- Zoo.
- YUlcer ntawm duodenum thiab plab.
Txhua yam teeb meem saum toj no yog NSAID-gastropathy. Yog li ntawd, cov kws kho mob feem ntau sim sau lawv cov neeg mob cov tshuaj qis tshaj plaws ntawm cov tshuaj uas tsis yog-steroidal anti-inflammatory siv tshuaj. Txhawm rau txo qhov tsis zoo ntawm lub plab thiab cov hnyuv, nws raug nquahu kom koj tsis txhob noj cov tshuaj no ntawm lub plab khoob, tab sis tsuas yog tom qab noj zaub mov loj xwb.
Tab sis teeb meem nrog rau lub plab zom mov tsis yog tag nrho cov kev mob tshwm sim uas qee qhov NSAIDs tuaj yeem ua rau. Qee yam tshuaj tuaj yeem ua rau lub plawv tsis zoo, nrog rau lub raum. Qee zaum lawv qhov kev txais tos tuaj yeem nrog mob taub hau thiab kiv taub hau. Lwm qhov teeb meem loj yog tias lawv muaj kev puas tsuaj rau cov pob txha mos intra-articular (ntawm chav kawm, tsuas yog nrog lub sijhawm ntev.daim ntawv thov). Hmoov zoo, ib tiam tshiab ntawm NSAIDs tam sim no muaj nyob rau hauv kev ua lag luam, uas tau tso tawm ntau ntawm cov kev tsis txaus no.
Tshiab tiam tshiab uas tsis yog-steroidal tshuaj tiv thaiv kab mob
Nyob rau hauv ob lub xyoo dhau los, ntau lub tuam txhab tshuaj tau ib txhij tau tsim cov NSAIDs tshiab niaj hnub, uas, nrog rau kev tshem tawm qhov mob thiab mob, yuav muaj kev phiv tsawg li ntau tau. Kev siv zog ntawm cov kws muag tshuaj tau ua tiav nrog kev ua tiav - tag nrho cov tshuaj tiam tshiab, hu ua xaiv, tau tsim.
Xav txog - cov tshuaj no nyob rau hauv kev saib xyuas ntawm tus kws kho mob tuaj yeem coj mus kawm ntev heev. Ntxiv mus, cov ntsiab lus tuaj yeem ntsuas tsis tau tsuas yog hauv lub lis piam thiab hli, tab sis txawm tias xyoo. Cov tshuaj los ntawm pab pawg no tsis muaj kev puas tsuaj rau cov pob txha pob txha, cov kev mob tshwm sim tsawg dua thiab xyaum tsis ua rau muaj teeb meem.
NSAIDs tiam tshiab yog cov tshuaj xws li:
- "Movalis".
- "Nise" (aka "Nimulid").
- "Arcoxia".
- "Celebrex".
Peb yuav qhia txog qee qhov ntawm lawv qhov zoo siv Movalis ua piv txwv. Nws muaj ob qho tib si hauv cov ntsiav tshuaj (7, 5 thiab 15 mg), thiab hauv suppositories ntawm 15 mg, thiab hauv iav ampoules rau kev txhaj tshuaj intramuscular (tseem 15 mg). Cov tshuaj no ua haujlwm maj mam, tab sis tib lub sijhawm zoo heev: tsuas yog ib ntsiav tshuaj txaus rau tag nrho hnub. Thaum tus neeg mob tau qhia rau kev kho mob mus ntev nrogmob hnyav arthrosis ntawm lub duav lossis lub hauv caug pob qij txha, "Movalis" tsuas yog hloov tsis tau.
Ntau hom ntawv uas NSAIDs raug tsim
Feem ntau ntawm cov tshuaj uas tsis yog-steroidal anti-inflammatory tuaj yeem yuav thiab siv tsis tau tsuas yog hauv daim ntawv ntawm cov ntsiav tshuaj thiab tshuaj ntsiav rau kev tswj qhov ncauj, tab sis kuj muaj tshuaj pleev, gels, suppositories thiab txhaj tshuaj. Thiab qhov no, ntawm chav kawm, yog qhov zoo heev, vim muaj ntau yam ua rau nws muaj peev xwm nyob rau qee kis kom tsis txhob raug mob thaum kho thaum tau txais cov txiaj ntsig kho sai.
Yog li, NSAIDs ntawm ib tiam tshiab, siv rau hauv daim ntawv ntawm kev txhaj tshuaj rau arthrosis, muaj ntau yam cuam tshuam rau lub plab zom mov. Tab sis muaj ib qho downside rau cov nyiaj npib no: thaum noj intramuscularly, yuav luag txhua cov tshuaj uas tsis yog-steroidal muaj peev xwm ua rau muaj teeb meem - necrosis ntawm cov leeg nqaij. Tias yog vim li cas NSAID txhaj tshuaj tsis tau siv sijhawm ntev.
Yeej, kev txhaj tshuaj yog muab rau exacerbation ntawm inflammatory thiab degenerative-dystrophic kab mob ntawm cov pob qij txha thiab txha nraub qaum, nrog rau qhov mob hnyav heev. Tom qab tus neeg mob tus mob zoo lawm, nws tuaj yeem hloov mus rau cov ntsiav tshuaj thiab cov neeg sawv cev sab nraud hauv daim ntawv tshuaj pleev.
Feem ntau, cov kws kho mob muab cov ntawv ntau npaum li cas, txiav txim siab dab tsi thiab thaum twg tuaj yeem nqa tau txiaj ntsig zoo tshaj plaws rau tus neeg mob. Cov lus xaus qhia nws tus kheej: yog tias koj tsis xav ua phem rau koj tus kheej los ntawm kev kho tus kheej ntawm cov kab mob xws li osteochondrosis lossis arthrosis, nrhiav kev pab los ntawm lub tsev kho mob, uas yog qhov chaw koj.pab tau.
NSAIDs tuaj yeem siv thaum cev xeeb tub
Cov kws kho mob tshwj xeeb tsis qhia cov poj niam cev xeeb tub kom noj NSAIDs (tshwj xeeb tshaj yog qhov kev txwv no siv rau peb lub hlis thib peb), nrog rau cov niam uas pub niam mis. Nws ntseeg tau tias cov tshuaj hauv pab pawg no tuaj yeem cuam tshuam rau kev coj tus menyuam hauv plab thiab ua rau muaj ntau yam tsis zoo hauv nws.
Raws li qee cov lus ceeb toom, xws li tshuaj tsis raug mob, raws li ntau yam, xws li Aspirin, tuaj yeem ua rau muaj kev pheej hmoo ntawm nchuav menyuam thaum ntxov. Tab sis qee zaum cov kws kho mob, raws li cov lus qhia, sau cov tshuaj no rau cov poj niam (hauv chav kawm tsawg thiab tsawg kawg nkaus). Nyob rau hauv txhua rooj plaub, yuav tsum txiav txim siab los ntawm ib tug kws kho mob tshwj xeeb.
Thaum cev xeeb tub, cov poj niam feem ntau muaj mob nraub qaum thiab yuav tsum tau daws qhov teeb meem no nrog cov tshuaj uas tsis yog tshuaj steroidal los tiv thaiv kab mob ua kom zoo tshaj plaws thiab ua haujlwm sai. Hauv qhov no, kev siv "Voltaren gel" tau txais. Tab sis - dua - nws txoj kev siv ywj pheej tsuas yog ua tau nyob rau hauv thawj thiab thib ob peb lub hlis twg, thaum cev xeeb tub lig, kev siv cov tshuaj muaj zog no tsuas yog tso cai nyob rau hauv kev saib xyuas ntawm kws kho mob.
Zoo kawg
Peb tau qhia koj yam peb paub txog NSAIDs. Deciphering cov ntawv luv, kev faib cov tshuaj, cov cai ntawm kev noj lawv, cov ntaub ntawv hais txog kev phiv - qhov no tuaj yeem pab tau hauv lub neej. Tab sis peb xav kom peb cov neeg nyeem xav tau cov tshuaj tsawg li tsawg tau. Yog li ntawd, hauv kev sib faib, peb xav kom koj noj qab haus huv heroic!
