Aminosalicylic acid (Aminosalicylic acid): cov lus qhia rau kev siv. Kev npaj muaj cov tshuaj nquag aminosalicylic acid

Cov txheej txheem:

Aminosalicylic acid (Aminosalicylic acid): cov lus qhia rau kev siv. Kev npaj muaj cov tshuaj nquag aminosalicylic acid
Aminosalicylic acid (Aminosalicylic acid): cov lus qhia rau kev siv. Kev npaj muaj cov tshuaj nquag aminosalicylic acid

Video: Aminosalicylic acid (Aminosalicylic acid): cov lus qhia rau kev siv. Kev npaj muaj cov tshuaj nquag aminosalicylic acid

Video: Aminosalicylic acid (Aminosalicylic acid): cov lus qhia rau kev siv. Kev npaj muaj cov tshuaj nquag aminosalicylic acid
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Hlis ntuj nqeg
Anonim

Tuberculosis yog ib yam kab mob txaus ntshai uas tuaj yeem cuam tshuam rau cov kabmob sab hauv ntawm tus neeg. Hauv qab lub tshuab tseem ceeb, lub ntsws poob, ces lub raum, zais zis, pob txha, thiab lwm yam. Thaum tsis muaj kev kho mob raws sij hawm thiab muaj txiaj ntsig, tus kab mob no nce nrawm, ua rau muaj qhov tshwm sim loj heev thiab txawm tuag. Yog li ntawd, nws tseem ceeb heev uas yuav tau siv cov tshuaj txhim khu kev qha uas tuaj yeem kov yeej tus mob no.

Piv txwv li, cov tshuaj raws li aminosalicylic acid uas muaj kev tiv thaiv tuberculosis siab. Qhov no yuav tham hauv qab no.

Sad statistics

Raws li qee cov lus ceeb toom, cov pej xeem ntawm Lavxias Federation muaj kaum npaug feem ntau yuav kis tus kab mob tubercle bacillus dua li cov neeg nyob hauv cov tebchaws nyob sab Europe. Nws yuav tsum raug sau tseg tias txhua ntu ntawm cov pej xeem muaj kev pheej hmoo. Yog li ntawd, txawm nyob hauv tsev neeg vam meej yeej muaj tus kab mob.

Cov tsos mob tuberculosis

Thawj cov cim qhia hauv cov neeg laus uas tuaj yeem ua rau muaj qhov mobtubercle bacillus yog:

  • hnoos ntev uas txuas ntxiv nrog kev kho tus qauv
  • muaj cov kua paug thiab cov ntshav tawm hauv cov hnoos qeev,
  • piav tsis tau, thaum xub thawj siab ib muag, nce hauv lub cev kub rau subfebrile qhov tseem ceeb,
  • txo qis qab los noj mov,
  • poob ceeb thawj,
  • qaug zog vim tsis paub meej.
  • Thawj cim ntawm tuberculosis
    Thawj cim ntawm tuberculosis

Yog tias pom muaj ib lossis ntau dua ntawm cov paib no, tus neeg mob yuav tsum tau mus ntsib kws kho mob tam sim ntawd kom tau tswv yim. Hauv cov xwm txheej zoo li no, tus kws tshaj lij xa ib tus neeg mus rau X-ray ntawm lub ntsws (fluorography). Yog tias daim duab qhia pom tias muaj qhov focal ntau tshaj 1 cm hauv txoj kab uas hla, tus neeg mob tuaj yeem xav tias muaj kab mob ntsws thiab tuaj yeem kuaj ntxiv. Yog tias qhov tshwm sim zoo, nws yuav tsum tau pib kho tus kab mob tam sim ntawd.

Aminosalicylic acid feem ntau yog cov tshuaj xaiv.

Kev piav qhia ntawm cov khoom thiab cov neeg sawv cev

tshuaj npe - 4-amino-2-hydroxybenzoic acid.

Formula - C7H7NO3.

Latin lub npe - aminosalicylic acid.

Sab nraud, cov khoom yog cov hmoov dawb uas muaj cov muaju me me. Yellowish lossis pinkish ntxoov yog tau. Tsis muaj ntxhiab tsw.

Tus neeg sawv cev tseem ceeb ntawm cov tshuaj no hauv khw muag tshuaj yog kev npaj muaj cov ntsev ntawm aminosalicylic acid - sodium aminosalicylate. Muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj rau kev tswj qhov ncauj. Tsis tas li, cov tshuaj nquag muaj nyob rau hauv daim ntawv ntshiab raws li kev daws rau infusion.

Sodium aminosalicylate
Sodium aminosalicylate

Pharmacological action

Cov tshuaj inhibits cov synthesis ntawm folic acid nyob rau hauv microbial cell, yog li tiv thaiv nws cov hauj lwm zoo. Tshwj xeeb tshaj yog nquag aminosalicylic acid rhuav tshem cov hlwb ntau. Nws tau xyaum tsis muaj kev cuam tshuam rau mycobacteria nyob rau theem so. Yog li ntawd, kev npaj aminosalicylic acid tsis tuaj yeem yog tib txoj kev kho rau tuberculosis. Lawv yuav tsum tau siv ua ke nrog lwm cov tshuaj tiv thaiv kab mob.

Ntxim qab kawg, aminosalicylic acid slows cia txoj kev loj hlob ntawm tsis kam mus rau lwm yam tshuaj.

Cov lus qhia rau kev siv

Tuberculosis tsuas yog qhia rau kev siv cov tshuaj no. Nws yog tsim nyog hais tias nyob rau hauv cov tshuaj niaj hnub no, thaum xaiv ib txoj kev kho rau tuberculosis, nws feem ntau muab nyiam rau lwm yam, tshiab thiab zoo dua tshuaj.

YContraindications

Txhua cov tshuaj uas muaj cov tshuaj nquag "aminosalicylic acid" muaj cov txiaj ntsig zoo rau tag nrho lub cev ntawm tus neeg mob, yog li muaj ntau yam xwm txheej uas siv cov tshuaj raws li nws tau txwv nruj heev. Cov no suav nrog:

  • Kev cuam tshuam ntawm lub raum ua haujlwm.
  • Lub siab tsis ua hauj lwm.
  • Hepatitis.
  • Cirrhosis ntawm daim siab.
  • Amyloidosis.
  • YPeptic ulcer ntawm lub plab thiab duodenum.
  • Mixedema.
  • Kev cev xeeb tub txhua lub sijhawm.
  • Muajintolerance rau aminosalicylic acid thiab nws cov ntsev.
  • cev xeeb tub malaise
    cev xeeb tub malaise

Side effects

Cov tshuaj muaj tshuaj lom heev, yog li nws tuaj yeem cuam tshuam rau kev ua haujlwm ntawm ntau lub cev thiab lub cev ntawm lub cev, ua rau muaj kev cuam tshuam tsis zoo. Namely:

  • Lub plab zom mov feem ntau raug kev txom nyem tshaj plaws, vim tias nws dhau los ntawm txoj hnyuv uas cov tshuaj nkag mus, ua rau xeev siab, ntuav, mob plab, plab zom mov, raws plab.
  • Lub paj hlwb kuj yuav cuam tshuam me ntsis. Tias yog vim li cas qee tus neeg mob pom tias muaj kev ntxhov siab ntau ntxiv, kev loj hlob ntawm kev puas siab puas ntsws.
  • Lub siab ua rau muaj zog. Yog li, cov kev mob tshwm sim yuav tsum muaj xws li jaundice, nce hauv siab ntim, mob hauv txoj cai hypochondrium.
  • Cov kev hloov pauv kuj tshwm sim hauv cov kab mob hematopoietic. Piv txwv li, tus lej ntawm leukocytes, platelets thiab eosinophils tau txo qis.
  • Nyob rau hauv cov ntaub ntawv ntawm kev siv ntev ntawm cov tshuaj ntau, cov thyroid caj pas kuj raug kev txom nyem. Tej zaum txoj kev loj hlob ntawm goiter, hypothyroidism.
  • Tsis tshua muaj, tab sis nws muaj peev xwm tsim cov tshuaj tiv thaiv kab mob hauv daim ntawv khaus thiab pob khaus ntawm daim tawv nqaij.
  • Khaus khaus ntawm daim tawv nqaij
    Khaus khaus ntawm daim tawv nqaij

Cov lus qhia tshwj xeeb

Rau kev kho mob zoo tshaj plaws, koj yuav tsum siv cov aminosalicylic acid thiab nws cov ntsev ua ke nrog lwm cov tshuaj tiv thaiv kab mob. Txwv tsis pub, txoj kev kho yuav tsis zoo.

Yuav siv thiabdosage

Cov tshuaj yog npaj rau kev tswj qhov ncauj. Ib ntsiav tshuaj ntawm cov tshuaj yuav tsum tau noj ntawm qhov ncauj nrog ib tug txaus tus nqi ntawm cov dej huv. Tsis txhob hloov nrog tshuaj yej, kas fes, cawv, mis nyuj thiab lwm yam dej qab zib. Qhov no yuav cuam tshuam rau kev nqus cov tshuaj.

Raws li cov ntaub ntawv teev tseg hauv cov lus qhia rau kev siv aminosalicylic acid, qhov ntau npaum li cas yuav tsum raug xaiv ib tus zuj zus rau txhua tus neeg mob thiab suav nrog cov mis 150-300mg / kg / hnub. Qhov kev txais tos yuav tsum yog 3-4 zaug hauv ib hnub.

Rau cov neeg laus, raws li txoj cai, muaj cov kev kho mob hauv qab no: 3-4 grams 3 zaug hauv ib hnub tom qab noj mov.

Cov ntsiav tshuaj rau kev tswj qhov ncauj
Cov ntsiav tshuaj rau kev tswj qhov ncauj

Cov ntsiab lus ntawm kev xa tawm los ntawm chaw muag tshuaj

Para-aminosalicylic acid (PAS) yog ib qho tshuaj noj. Nws tau txais los ntawm cov tsev kho mob thiab cov chaw muag tshuaj nrog cov cai tshwj xeeb. Yuav kom yuav cov khoom no, tus neeg zoo tib yam xav tau daim ntawv sau tshuaj nyob rau hauv daim ntawv qhia tshwj xeeb, uas yog kws kho mob sau.

Tus neeg ua haujlwm kws tshuaj xyuas qhov tseeb ntawm cov ntaub ntawv, muaj txhua yam yuav tsum tau ua thiab cov ntsiab lus ntxiv. Yog tias qhov tshwm sim txaus siab, cov tshuaj txo qis.

Kws tshuaj thiab tshuaj
Kws tshuaj thiab tshuaj

Zoo kawg

Thaum pom thawj cov tsos mob thiab cov tsos mob ntawm tuberculosis nyob rau hauv cov neeg laus thiab cov me nyuam, nws yog ib qho tseem ceeb kom ua txhua yam kev ntsuas los txheeb xyuas tus kab mob thiab rhuav tshem nws.

Kev npaj raws li aminosalicylate tau pom lawv tus kheej ua cov neeg ua haujlwm tau zoo rau ntau xyoo. Txawm li cas losNws yuav tsum nco ntsoov tias lawv yuav tsum tau noj tsuas yog raws li kws kho mob tau sau tseg thiab ua ke nrog lwm cov tshuaj tiv thaiv kab mob. Hauv qhov no, tus neeg mob yuav muaj txhua txoj hauv kev kom rov zoo tag nrho.

Pom zoo: