Vim ib lub ntsiab lus tseem ceeb hauv kev lag luam kho mob niaj hnub no yog kev tshawb fawb txog kev ua neej ntxiv thiab kev txhim kho kev noj qab haus huv, qhov teeb meem ntawm kev kawm txog kev cuam tshuam ntawm cov dawb radicals ntawm tib neeg lub cev kuj tau tsa. Hmoov tsis zoo, txhua txoj haujlwm hauv cheeb tsam no raug cuam tshuam rau kev lag luam, yog li cov neeg uas tsis muaj tshuaj lom neeg tau txais cov ntaub ntawv tsis raug lossis tsis tiav. Tsawg tus neeg paub tias tsis yog tag nrho cov dawb radicals muaj teeb meem rau tib neeg lub cev. Cov neeg feem coob yuav thiab siv cov tshuaj uas tshem tawm cov radicals yam tsis tau xav txog seb nws puas tsim nyog. Txij li cov kev cai lij choj ntawm kev lag luam yog thawj qhov chaw hauv lub ntiaj teb niaj hnub no, cov tshuaj antioxidants, tshaj tawm hauv ntau txoj hauv kev, yog kim heev. Tab sis thawj cov dawb radicals hauv tib neeg lub cev tsis tsuas yog tsis tas yuav raug tshem tawm, tab sis, ntawm qhov tsis sib xws, lawv cov khoom tsim tawm yuav tsum tau txhawb nqa. Lawv koom nrog hauv cov txheej txheem metabolic thiab pab sib ntausntau yam kab mob. Tab sis cov dawb radicals thib ob yog teeb meem thiab ua rau ntau yam kab mob.
Ua ntej noj cov tshuaj antioxidants lossis ntau cov vitamin complexes, koj yuav tsum nkag siab tias lawv xav tau npaum li cas, thiab qhov twg lawv yuav tsum tau siv. Thawj cov dawb radicals yog oxygen radicals thiab nitric oxide thiab lipids. Thawj ntawm lawv tshwm sim los ntawm kev ua haujlwm ntawm phagocytes thiab macrophages hauv hlwb. Txij li cov dawb radicals yog cov molecules uas tsis muaj ib tug khub electron nyob rau hauv lub sab nrauv orbit, lawv yog chemically active. Ua tsaug rau lub built-in genetic tiv thaiv mechanism, hlwb tau tshem ntawm xws li molecules los ntawm cov tshuaj tiv thaiv. Tom qab cov tshuaj tiv thaiv no, hydrogen peroxide yog tsim. Nws yog siv los ntawm phagocytes thiab macrophages rau lawv cov dej num, nws rhuav tshem lub plhaub sab nraud ntawm cov kab mob thiab microbes. Tab sis hydrogen peroxide nyob rau hauv lub xub ntiag ntawm hlau yog hloov mus rau ib tug thib ob dawb hydroxyl radical. Nws yog tshuaj lom neeg thiab muaj peev xwm ua kom puas yuav luag txhua yam molecule hauv tib neeg lub cev.
Dawb radicals ntawm nitric oxide raug tso tawm thaum lub sijhawm ua haujlwm ntawm macrophages, nrog rau cov hlab ntsha hlwb. Lawv cov naj npawb ntawm cov metabolism hauv ib txwm yog nruj me ntsis normalized, qhov sib txawv ua rau kub siab lossis hypotension. Nyob rau hauv lub xub ntiag ntawm hydroxyl, lawv ua reactive thiab pib ua kom puas hlwb. Yog tias dawb oxygen radicals nkag mus rau hauv lipid hlwb, ces feem ntauactive kev puas tsuaj. Ib txoj saw hlau tau pib. Hydroxyl cuam tshuam nrog fatty acids uas yog ib feem ntawm cov cell membranes, uas ua rau tsim cov lipid radicals. Lawv nkag mus rau hauv cov tshuaj tiv thaiv ntxiv, tom qab ntawd lipid peroxidation tshwm sim. Qhov tshwm sim dawb radicals rhuav tshem cov cell membranes thiab cov protein sib txuas.
Kev puas tsuaj li no yog ib txwm muaj rau tib neeg lub cev, vim lawv lub hlwb tau hloov kho tas li. Tab sis cov dawb radicals rhuav tshem cov molecules, suav nrog cov uas muaj DNA codes. Lawv kuj paub yuav ua li cas rov qab, tab sis nrog xws li "thaum ntxov" tshwm sim, "tshuaj lom neeg yuam kev" tshwm sim. Vim li no, cov hlwb tshiab raug tsim tsis raug, thiab thaum kawg nres tsim.
Raws li tau hais los saum toj no, muaj cov kev npaj muaj cov tshuaj antioxidants los tua cov radicals. Cov no yog cov khoom uas pub dawb electron thiab tsis ua mob rau lub cev. Lawv, raws li nws tau, khi dawb radicals, tiv thaiv kev puas tsuaj saum cov qauv. Qhov tseeb, tib neeg lub cev muaj peev xwm tsim cov tshuaj antioxidants ntawm nws tus kheej. Tab sis ntau yam cuam tshuam rau qhov tshwm sim ntawm cov dawb radicals, thiab lawv cov tsos hauv lub cev dhau qhov kev cai. Txawm li cas los xij, tsis yog txhua cov tshuaj antioxidants, tshwj xeeb tshaj yog cov khoom tsim tawm, muaj txiaj ntsig zoo. Ib qho dhau ntawm lawv pib khi thiab thawj cov dawb radicals. Yog tias tsis muaj qhov qhia txog kev noj zaub mov kom zoo, ces qhov tseem ceeb yuav tsum yog kev noj zaub mov kom zoo, cov ntawv qhia zaub mov uas zoo tshaj plaws nrog tus kws qhia noj haus.
