Ntau yam pathologies ntawm daim siab thiab biliary system txhim kho tsis yog vim tus cwj pwm tsis zoo xwb, tab sis kuj yog vim kev coj tus cwj pwm tsis zoo, noj tsis txaus thiab nquag siv tshuaj. Tag nrho cov teeb meem tsis zoo no ua rau tsim cov pob zeb. Lub cev tsim ntau yam txheej txheem inflammatory. Cov kab mob no kho tau, uas yog nyob ntawm kev siv ntau yam tshuaj. Cov tshuaj nrov tshaj plaws yog "Grinterol". Analogues, cov lus qhia rau kev siv thiab contraindications yuav tau piav nyob rau hauv tsab xov xwm no.
Pharmacological hauv paus ntsiab lus ntawm kev ua
Cov tshuaj "Grinterol" belongs rau qeb ntawm hepatoprotectors haib. Cov tshuaj nquag nkag mus rau hauv daim nyias nyias ntawm daim siab hlwb thiab tiv thaiv lawv los ntawm kev cuam tshuam tsis zoo ntawm cov kua tsib. Cov tshuaj yuav txo tau tag nrho cov concentration ntawm lom lom acids, uas muaj zog toxicity. Cov neeg tsim khoom ntawm cov tshuaj "Grinterol" nco ntsoov tias cov cuab yeej no muaj ob pebBuffs:
- Cholagogue. Stimulates ntau lawm thiab excretion ntawm bile.
- Cholelitholytic. Pab yaj cov roj cholesterol me me uas tsim hauv lub gallbladder.
- Lipipidemic. Txo cov qib ntawm txoj hnyuv nqus ntawm lipophilic acids, ua rau lawv tshem tawm sai sai ntawm lub cev.
- Hypocholesterolemic. Qhov tseem ceeb txo qhov concentration ntawm cov roj (cholesterol) phem hauv cov ntshav.
Cov neeg mob tsis tshua pom cov analogues ntawm "Grinterol", vim tias cov tshuaj no muaj cov nyhuv immunomodulatory me ntsis. Cov cuab yeej muaj feem cuam tshuam rau txhua qhov kev cuam tshuam tseem ceeb uas tshwm sim hauv daim siab.
Kev sib sau thiab tso tawm daim ntawv
Cov tshuaj "Grinterol" muaj nyob rau hauv daim ntawv ntawm cov tshuaj ntsiav me. Cov khoom yog muag hauv blister packs ntawm 10 pieces. Ib pob ntawv yuav muaj li ntawm 5 mus rau 10 hlwv.
Ib lub tshuaj ntsiav muaj cov khoom xyaw hauv qab no:
- Cov tshuaj nquag yog ursodeoxycholic acid 250 mg.
- Cov khoom siv pabcuam: magnesium stearate, pob kws hmoov txhuv nplej siab, silicon dioxide.
Lub Hom Phiaj ntawm ursodeoxycholic acid
bile yog qhov tseem ceeb rau kev zom zaub mov kom raug. Ntau tus ntseeg tias yog tias cov tshuaj no tsim tawm hauv lub cev ntawm txhua tus neeg los ntawm lub siab tshwj xeeb, ces vim li cas thiaj noj tshuaj raws li nws? Thiab qhov tseem ceeb yog qhov muaj pes tsawg leeg ntawm cov kua tsib suav nrog ntau yam. Pebtsim universal acids uas emulsify tag nrho cov rog. Lub pathogenesis classical ntawm cholestatic daim siab kab mob yog raws li ib tug ntau ntawm cov hydrophobic tshuaj uas muaj ib tug tej yam toxicity rau noj qab haus huv cov ntaub so ntswg ntawm lub cev.
Cov kws tshaj lij tau txiav txim siab tias cov kua tsib yuav tsum tau hloov pauv kom nws muaj cov tshuaj muaj txiaj ntsig ntau dua. Qhov no tsuas yog ua tiav yog tias koj noj cov tshuaj uas muaj ursodeoxycholic acid.
Cov lus qhia rau kev siv
Ntau qhov kev tshuaj xyuas zoo txog "Grinterol" qhia tias cov tshuaj no muaj txiaj ntsig zoo hauv kev tawm tsam ntau yam kab mob. Cov kws kho mob tsim nyog feem ntau sau cov tshuaj no rau cov neeg mob uas tau kuaj pom muaj cov kab mob hauv qab no:
- Tshuaj kab mob ntawm cov ducts.
- YCystic fibrosis.
- Cholelithiasis (tab sis muab tias lub cev ua haujlwm ib txwm muaj).
- Cirrhosis ntawm daim siab los yog biliary reflux gastritis (yog tias tus neeg mob tsis muaj cov tsos mob ntawm decompensation).
- Kev hloov daim siab ib zaug noj qab nyob zoo rau hauv cov ntaub so ntswg rog.
Cov lus qhia rau kev siv "Grinterol" qhia tias cov tshuaj tsuas tuaj yeem yaj cov roj cholesterol, qhov loj ntawm qhov tsis pub tshaj 2-3 centimeters inch.
YContraindications
Analogues ntawm "Grinterol" yog qhov txaus siab rau cov neeg mob tsuas yog tias lawv tau contraindicated hauv kev siv cov tshuaj no. Tus kws kho mob yuav tsis kamsau tshuaj rau cov neeg mob uas muaj cov nram qab no contraindications:
- Qhov muaj cov txheej txheem mob hnyav hauv cov hnyuv, cov ducts, gallbladder.
- Nyob rhiab heev rau cov khoom uas tsim cov tshuaj.
- Kev muaj cov kab mob hauv lub gallstones (muaj calcium ntau).
- mob siab lossis raum tsis ua haujlwm.
- mob pancreatitis.
- Cov me nyuam hnub nyoog (txog 3 xyoos tsis sau tshuaj ntsiav).
- Cirrhosis ntawm daim siab (theem decompensation).
- Non-functioning gallbladder.
Tus neeg mob yuav tsum coj mus rau hauv tus account tag nrho cov contraindications. Txwv tsis pub, koj tsuas tuaj yeem ua rau lub xeev muaj kev noj qab haus huv xwb.
Cov lus qhia rau kev siv "Grinterol"
Analogues ntawm cov tshuaj no yuav tsum tau xaiv tshwj xeeb los ntawm tus kws kho mob tsim nyog. Yog hais tias tus neeg mob tsis muaj contraindications, ces nws yuav tsum tau muab ib tug tag nrho-fledged txoj kev kho raws li kev kawm tshuaj. Cov neeg mob uas lub cev hnyav dua 45 kg los yog muaj teeb meem nqos cov tshuaj ntsiav yuav tsum noj tshuaj nrog ursodeoxycholic acid nyob rau hauv ntau npaum li cas. Yog tias nws yog qhov tsim nyog kom ua tiav cov txiaj ntsig zoo ntawm cov roj cholesterol, ces koj yuav tsum ua raws li qee yam tshuaj. Rau 1 kg ntawm lub cev hnyav noj 10 mg ntawm cov tshuaj:
- Ntau tshaj 100 kg - 5 capsules.
- Txog 80 rau 99 kg - 4tshuaj.
- 60 txog 79 - siab kawg 3 capsules.
- Txog 59 kg - 2 ntsiav tshuaj ib hnub.
Cov ntsiav tshuaj yuav tsum tau nqos tag nrho nrog cov dej tsis muaj carbonated ntau. Cov tshuaj yog noj 1 zaug hauv ib hnub. Nws yuav siv sij hawm 6 mus rau 24 lub hlis rau cov pob zeb kom yaj. Yog tias tom qab ib xyoos lub pob zeb tsis tau txo qis, ces kev kho mob yuav tsum tau nres. Kev kho mob yuav tsum tau kuaj xyuas txhua rau lub hlis. Rau cov hom phiaj no, cov kws kho mob tshwj xeeb siv X-ray lossis ultrasound. Cov kws kho mob kuj kuaj xyuas seb cov pob zeb puas muaj calcified. Yog tias qhov no tshwm sim, ces kev kho mob yuav tsum raug tso tseg.
Rau kev tawm tsam zoo tiv thaiv kab mob plab reflux gastritis, siv 250 mg ntawm cov tshuaj ib hnub. Cov tshuaj tsuas yog noj thaum mus pw. Txoj kev kho yuav kav li ob lub lis piam. Kev ncua ntawm chav kawm nyob ntawm tus neeg mob tus mob. Tias yog vim li cas txhua daim duab kho mob raug txiav txim siab ntawm tus kheej.
Rau qhov kev kho mob zoo ntawm cov kab mob biliary cirrhosis thawj zaug, qhov kev pom zoo yog xaiv raws li tus neeg mob lub cev qhov hnyav. Qhov siab tshaj plaws ntawm 7 capsules ib hnub tuaj yeem noj. Thawj peb lub hlis, cov tshuaj tau noj thaum nruab hnub, faib cov koob tshuaj txhua hnub los ntawm 3 zaug. Nws yog ib qho tsim nyog yuav tsum tau ua raws li kev cai txais tos. Thawj hnub tus neeg mob yuav pom cov tsos mob tshwm sim ntau ntxiv. Hauv qhov xwm txheej zoo li no, kev kho mob tsis raug tso tseg, lawv tsuas yog noj 250 mg ntawm cov tshuaj ib hnub. Cov koob tshuaj tau nce zuj zus mus txog thaum cov tshuaj tau hais tseg.
Kev siv "Grinterol" tuaj yeem txo qis kev loj hlob ntawm cov kua tsib, nresKev nce qib ntawm cov kev hloov pauv hauv histological thiab txawm tias tshem tawm cov kev hloov pauv tsis xav tau hepatobiliary, yog tias kev kho mob pib thaum ntxov ntawm cystic fibrosis.
kev tawm tsam tsis zoo
Cov lus qhia rau "Grinterol" qhia tias ntau tshaj qhov kev tso cai noj yog fraught nrog kev tsis zoo ntawm tus neeg mob. Nyob rau hauv tas li ntawd, lub digestive system, daim siab, biliary ib ntsuj av, cov ntaub so ntswg mos yuav raug kev txom nyem. Qee cov neeg mob yws ntawm raws plab thiab ntuav. Nyob rau hauv cov xwm txheej zoo li no, nws yog ib qho tsim nyog los txo cov koob tshuaj txhua hnub. Yog hais tias qhov tsis zoo tshwm sim tsis nres, ces qhov kev kho mob raug muab tso tseg.
Cov kab mob ua xua thoob plaws lub cev tsis suav nrog. Yog tias tus neeg mob tau txais kev kho mob rau tus kab mob biliary cirrhosis thawj zaug, cov kev tshwm sim hauv qab no yuav tshwm sim:
- mob plab sab xis sab xis.
- Kev hloov pauv ntawm daim siab mob siab.
Yog tus neeg mob pom tias muaj kev noj qab haus huv tsis zoo, ces nws yuav tsum tau ceev nrooj nrhiav tus kws kho mob. Hauv qhov xwm txheej zoo li no, yuav tsum tau hloov pauv "Grinterol".
Cov lus qhia tshwj xeeb
Kev sim tshuaj ntawm "Grinterol" tau pom tias cov tshuaj no muaj qee qhov nuances. Lawv yuav tsum tau txiav txim siab ua ntej yuav cov tshuaj. Txoj kev no koj tuaj yeem zam qhov yuam kev ntau tshaj plaws thiab txo qhov kev pheej hmoo ntawm kev mob tshwm sim.
Cov Lus Qhia Tshwj Xeeb:
- Cov tshuaj "Grinterol" tsis ua rau qaug zog thiab tsis txo cov tshuaj tiv thaiv. Vim li no, cov neeg mobtuaj yeem tsav thiab ua cov haujlwm uas yuav tsum tau ua kom muaj zog ntxiv.
- Thaum kho, koj yuav tsum tau sim ua ntu zus los tswj kev ua haujlwm ntawm lub cev.
- Tag nrho cov kev kho mob yuav tsum nyob rau hauv kev saib xyuas nruj ntawm cov kws kho mob.
- Ib qho piv txwv ntawm "Grinterol" yog qhov tsim nyog yog tias tom qab 12 lub hlis ntawm kev siv tshuaj, tus neeg mob tsis muaj qhov zoo ntawm kev tawm tsam tus kabmob.
- Thaum cev xeeb tub, siv cov tshuaj tsuas yog qhov kev pheej hmoo ntawm kev phom sij rau tus menyuam tsawg kawg nkaus.
- Qhov tshwj xeeb muaj pes tsawg leeg ntawm "Grinterol" pab daws tsuas yog cov lej me thiab nruab nrab.
- Tom qab tshem cov pob zeb roj cholesterol, kev kho yuav tsum txuas ntxiv mus ntxiv 3 lub hlis. Ua tsaug rau qhov no, nws muaj peev xwm yaj cov seem ntawm calculi thiab tiv thaiv kom tsis txhob muaj qhov tshwm sim ntawm pathology.
Tshuaj tsis sib tov zoo nrog cawv. Yog vim li cas thaum lub sij hawm kho koj yuav tsum tsis txhob haus cawv.
Kev tshawb fawb soj ntsuam ntawm cov tshuaj ntawm tus menyuam hauv plab tau ua tiav tshwj xeeb rau tsiaj. Cov kws tshaj lij tsis tau qhia txog cov teebmeem carcinogenic lossis mutagenic. Nws tuaj yeem siv "Grinterol" thaum cev xeeb tub nkaus xwb yog tias qhov txiaj ntsig rau leej niam siab dua qhov kev pheej hmoo rau tus menyuam hauv plab. Tsis muaj ntaub ntawv hais txog kev tso tawm cov khoom ntawm cov tshuaj nrog rau cov kua mis, yog li ntawd, thaum siv cov tshuaj, nws yog qhov zoo dua los hloov tus menyuam mus rau cov khoom sib xyaw ua ke.
Cov kws kho mob feem ntau sau tshuaj rau cov menyuam yaus hnub nyoog peb xyoos. Cov menyuam yaus tuaj yeem muaj teeb meem nqos cov tshuaj ntsiav, yog li cov tshuaj yuav raug muab ncua.
Kev sib tham nrog lwm yam tshuaj
Txhua tus neeg mob feem ntau txaus siab rau cov lus qhia rau kev siv "Grinterol" thiab cov tshuaj analogues ntawm cov tshuaj no. Tab sis nws tseem ceeb heev uas yuav tau xav txog qhov tseeb ntawm cov tshuaj. Rau kev kho mob kom tau txais txiaj ntsig tiag tiag, kev sib cuam tshuam tshuaj yeeb tshuaj yuav tsum raug txiav txim siab:
- "Grinterol" ob peb zaug txhim kho cov nyhuv ntawm cyclosporine, uas yog vim li cas cov tshuaj noj nrog cov tshuaj no yuav tsum raug txo.
- Cov tshuaj tua kab mob zoo raws li cov ntsev txhuas thiab cholestyramine yuav tsum tau noj ntau tshaj 2 teev ua ntej "Grinterol". Txwv tsis pub, qhov kev txiav txim ntawm hepatoprotector yuav raug txo.
- Classic tshuaj tiv thaiv qhov ncauj txo qis lub peev xwm ntawm ursodeoxycholic acid kom yaj cov roj cholesterol uas twb muaj lawm. Tias yog vim li cas nws yog qhov zoo dua tsis kam txais cov nyiaj no thaum kho nrog "Grinterol".
- Cov tshuaj txo cov txiaj ntsig ntawm ciprofloxacin. Rau kev kho kom zoo, tus kws kho mob yuav tsum xaiv cov tshuaj noj kom raug.
Yog tias tus kws kho mob tau sau ntawv "Grinterol" rau kev kho cov pob zeb hauv lub gallstone, ces koj yuav tsum tau mus kuaj hauv tsev kho mob tsis tu ncua. Rau lub sijhawm ntawm kev kho tshuaj, tus neeg mob yuav tsum tau pub ntshav ib ntus rau kev tshuaj xyuas,Nyob rau hauv ultrasound ntawm lub gallbladder, nrog rau multifunctional cholecystography. Tsuas yog nyob rau hauv rooj plaub no nws muaj peev xwm tswj tau cov txiaj ntsig ntawm kev kho mob.
Analogues ntawm "Grinterol"
Kev hloov pheej yig rau cov tshuaj hepatoprotector no feem ntau txaus siab rau cov neeg mob uas muaj contraindications rau kev siv tshuaj. Cov cuab yeej hauv qab no tau zoo tshaj plaws:
- Ursosan.
- Ursofalk.
- Ursodez.
- Urdoksa.
- Exhole.
- Livodex.
- Ursoliv.
- Choludexan.
- Odeston.
- Flamin.
- "Hofitol".
- Artichoke Extract.
Kev tshuaj xyuas ntau ntawm cov tshuaj analogues ntawm "Grinterol" qhia tias cov khw muag tshuaj niaj hnub muaj ntau yam tshuaj uas ua haujlwm zoo nrog cholelithiasis. Tab sis tus kws kho mob yuav tsum xaiv qhov yog!
Kev kho mob ua tau zoo ntawm cov tshuaj analogues "Grinterol"
Kev tshawb fawb txog cov txiaj ntsig zoo ntawm ursodeoxycholic acid tau ua thoob ntiaj teb txij li xyoo 90s ntawm lub xyoo pua xeem. Cov kws tshaj lij muaj peev xwm ua pov thawj tias cov tshuaj nrog cov tshuaj no muaj txiaj ntsig zoo rau kev kho tus kab mob biliary cirrhosis. Kev siv ursodeoxycholic acid ntawm 14 mg ib hnub twg txo qis cov cim qhia ntawm cholestasis hauv cov neeg mob thiab tshem tawm.kev loj hlob ntawm ib tug txaus ntshai pathology.
Hauv tebchaws Russia, pheej yig analogues ntawm "Grinterol" yog qhia rau cov kab mob cholestatic hauv qab no:
- YCystic fibrosis.
- Intrarenal cholestasis ntawm cev xeeb tub.
- Primary sclerosing cholangitis.
- Cholestasis los ntawm parenteral khoom noj khoom haus.
pheej yig analogues ntawm "Grinterol" muaj qhov tsim nyog ua haujlwm txawm tias mob siab rau daim siab. Piv txwv li, hauv xyoo 2000, cov kws tshaj lij tau ua ntau yam kev tshawb fawb ntawm cov placebo-tswj cov neeg mob uas muaj kab mob siab cawv. Raws li qhov tshwm sim, kev kuaj lub siab ua haujlwm tau zoo dua tom qab noj 16mg / kg rau ib hlis.
Cov lus pov thawj tus neeg mob
Cov tshuaj "Grinterol" yog qhov xav tau, vim tias nrog kev pab ntawm cov tshuaj no koj tuaj yeem kov yeej kab mob gallstone. Kev tshuaj xyuas tus neeg mob yog qhov zoo. Cov neeg sau tseg tias cov tshuaj muaj txiaj ntsig zoo, vim tias nws tuaj yeem siv los kho cov menyuam yaus hnub nyoog peb xyoos. "Grinterol" tsis cuam tshuam rau lub peev xwm tsav tsheb, nrog rau cov txheej txheem txaus ntshai. Kev noj cov tshuaj txhais tau hais tias yuav tsum tau sab laj nrog kws kho mob. Qhov ntau npaum li cas yog xam los ntawm tus kheej, raws li txhua yam nyob ntawm tus neeg mob tus mob.
