"Prednisolone" intramuscularly: cov lus qhia rau kev siv, ntau npaum li cas

Cov txheej txheem:

"Prednisolone" intramuscularly: cov lus qhia rau kev siv, ntau npaum li cas
"Prednisolone" intramuscularly: cov lus qhia rau kev siv, ntau npaum li cas

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Video: Prednisolone - Mechanism, side effects, precautions & uses 2024, Kaum ib hlis
Anonim

Intramuscularly "Prednisolone" yog siv los kho ntau yam kab mob. Cov tshuaj no belongs rau qeb ntawm glucocorticosteroid cov tshuaj hormones. Koj tuaj yeem siv nws tsuas yog tom qab sab laj nrog koj tus kws kho mob, vim tias kev txhaj tshuaj muaj ntau contraindications thiab kev phiv txaus ntshai. Feem ntau, cov tshuaj tau muab rau cov neeg mob uas siv cov tshuaj uas tsis yog-steroidal anti-inflammatory siv tsis tau.

Kev sib xyaw thiab ntau npaum li cas ntawm cov tshuaj

Hauv cov tshuaj ib txwm siv, txhawm rau tshem tawm qhov mob, cov kws kho mob txhaj tshuaj "Prednisolone" intramuscularly. Cov tshuaj yog muag nyob rau hauv me me ampoules. Cov tshuaj yog meej, nrog me ntsis tint ntawm ntsuab los yog daj. Cov khoom muaj xws li cov hauv qab no:

  • Cov khoom xyaw tseem ceeb yog Prednisolone, 30 mg.
  • Nyob zoo ib tsoom niam txiv kwv tij neej tsa sawv daws.
  • Ncotinamide Ncotinamide

  • Metabisulphite thiab sodium hydroxide.
  • Edetat disodium.

Ib pob muaj ib daim duab los qhia nrog peb cov tshuaj ampoules. Cov tshuaj nquag yog cov khoom sib txuas ntawm cov tshuaj hormones, uas yog tsim los ntawm cov qog adrenal. Kev taw qhia ntawm "Prednisolone" intramuscularly muaj lub zog tiv thaiv kab mob, tiv thaiv kab mob thiab tshuaj tua kab mob rau tus neeg mob lub cev.

Nrog kev siv tas li, cov tshuaj txo cov concentration ntawm cov tshuaj hauv lub cev uas ua rau kom cov phab ntsa ntawm cov hlab ntsha thiab cov nqaij mos. Ua tsaug rau qhov no, nws muaj peev xwm zam kom tsis txhob muaj kev loj hlob ntawm puffiness, tshem tawm qhov mob, txo qhov rhiab heev ntawm cov paj hlwb, ua rau kom cov piam thaj hauv cov ntshav nce ntxiv, thiab tseem ua kom tshem tawm cov ntsev ntsev ntawm lub cev. "Prednisolone" zoo kawg nkaus restores dej thiab electrolyte tshuav.

Duab "Prednisolone" nyob rau hauv ib lub pob txheem
Duab "Prednisolone" nyob rau hauv ib lub pob txheem

Lub hauv paus ntsiab lus cuam tshuam rau lub cev

Kev taw qhia ntawm "Prednisolone" intramuscularly tso cai rau koj kom ua tiav qhov kev pom zoo los tiv thaiv kev poob siab, tiv thaiv kab mob, tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob. Ib zaug hauv tus neeg mob lub cev, cov tshuaj tsim ib qho tshwj xeeb glucocorticoid receptor. Cov tshuaj nquag nkag mus rau hauv lub cell nucleus, qhov chaw uas nws cuam tshuam nrog cov noob. Vim li no, kev hloov pauv loj yog tsim los ntawm RNA thiab cov proteins. Hauv cov tshuaj, Prednisolone muaj nuj nqis heev rau nws cov tshuaj tiv thaiv kab mob zoo heev, uas tau ua tiav vim muaj cov hauv qab no:

  • Cov khoom tseem ceeb tiv thaiv kev sib pauv ntawm cov noob los ntawm pawg COX-2. Vim li no, kev tsim cov prostaglandins txo qis.
  • Cov khoom xyaw nquag ua rau ntau zaus ua rau lub ntuj tsim ntawm lipocortin, uas tiv thaiv kev tsim ntawm phospholipase. Qhov no tiv thaiv cov ntaub so ntswg puas los ntawm kev tsim arachidonic acid.
  • Cov tshuaj nres cov txheej txheem metabolic ntawm cov molecules hauv cov hlab ntsha, kom cov monocytes thiab neutrophils tsis nkag mus rau hauv qhov mob ua kom pom tseeb.
Ntim "Prednisolone"
Ntim "Prednisolone"

Cov lus qhia rau kev siv

Koj tuaj yeem siv cov tshuaj tsuas yog tom qab tus neeg mob tau ua tib zoo kawm cov lus qhia rau "Prednisolone". Kev txhaj tshuaj intramuscular tsuas yog siv yog tias cov kab mob hauv qab no tau kuaj pom:

  1. Cov kab mob ntawm daim tawv nqaij tsis muaj zog (psoriasis, pemphigus, eczema, Duhring's disease, exfoliative dermatitis, Lyell's syndrome).
  2. Hepatitis.
  3. Aspiration thiab eosinophilic pneumonia, pulmonary tuberculosis.
  4. YGranulomatous thyroiditis.
  5. Multiple sclerosis.
  6. Cov kab mob ntev thiab mob hnyav uas tau nrog cov txheej txheem inflammatory hauv cov pob qij txha thiab cov ntaub so ntswg ze.
  7. mob ntsws cancer.
  8. Edema ntawm lub hlwb.
  9. kab mob ua xua.
  10. rheumatic ua npaws, chorea, rheumatic lub plawv.
  11. mob plab plab.
  12. Hypercalcemia tsim tawm tsam keeb kwm yav dhau los ntawm kev muaj oncological neoplasms.
  13. Nephrotic Syndrome.
  14. Diffuse lesions ntawm cov ntaub so ntswg sib txuas.
  15. Pathology uas cuam tshuam nrog hematopoiesis (anemia, leukemia).
  16. Cov kab mob hypoglycemic.
  17. Congenital adrenal hyperplasia lossis ua haujlwm tsis zoo ntawm lawv lub cortex.
  18. Pib thiab theem nrab hypocorticism.
  19. kab mob autoimmune.
  20. Pathologies ntawm lub cev tsis pom kev (uveitis, allergic conjunctivitis, allergic ulcerative keratitis, choroiditis, sympathetic ophthalmia, iridocyclitis).
  21. Cov kab mob sib kis ntawm lub ntsws (mob alveolitis, fibrosis, sarcoidosis).

Ntau tus neeg mob nyiam siv "Prednisolone" hauv ampoules. Kev txhaj tshuaj intramuscular tsuas yog tom qab kev sab laj nrog tus kws kho mob ua ntej. Cov tshuaj yuav tsum tau muab tshuaj rau anaphylactic poob siab los yog kev tawm tsam ntawm cov zaub mov tsis haum. Ob peb hnub tom qab, tus neeg mob raug xa mus rau kev kho mob ntsiav tshuaj.

Kev daws rau kev txhaj tshuaj intramuscular
Kev daws rau kev txhaj tshuaj intramuscular

YContraindications

Ua ntej koj paub yuav ua li cas txhaj "Prednisolone" intramuscularly, koj yuav tsum paub koj tus kheej nrog cov npe ntawm cov xwm txheej thiab cov kab mob uas nws txwv tsis pub siv cov tshuaj no. Txawm tias muaj xwm txheej ceev tshaj plaws, nws raug txwv nruj heev los tswj cov tshuaj yog tias muaj qhov tsis haum rau cov tshuaj nquag ntawm cov tshuaj. Lub ntsiab contraindications suav nrog:

  1. Kab mob ntawm plab hnyuv, uas yog fraught nrog los ntshav sab hauv.
  2. AIDS, HIV.
  3. Cov kab mob sib kis hnyav: tuberculosis, herpes zoster lossis herpes yooj yim, qhua pias, kab mob qhua pias.
  4. Pab, kab mob, kab mob lossis kab mob fungal ntawm lub cev.
  5. mob siab lossis lub raumua tsis tiav.
  6. Kev txawv txav hnyav hauv lub cev endocrine.
  7. nce ntshav albumin ntau ntau.
  8. Pathology hauv kev ua haujlwm ntawm cov hlab plawv.
  9. mob puas siab puas ntsws: schizophrenia, qaug dab peg, psychosis.

Txhua pab pawg muaj kev pheej hmoo tau piav qhia ntxaws los ntawm cov chaw tsim khoom hauv cov lus qhia rau kev siv Prednisolone. Kev txhaj tshuaj intramuscular yog muab rau cov neeg laus tsuas yog tom qab kuaj tag nrho.

Kev taw qhia txog kev txhaj tshuaj ntawm "Prednisolone"
Kev taw qhia txog kev txhaj tshuaj ntawm "Prednisolone"

Cov lus qhia rau kev siv

Intramuscularly "Prednisolone" yog siv nrog ceev faj heev. Cov koob tshuaj ib txwm xaiv ib tus zuj zus, vim tias txhua yam nyob ntawm qhov hnyav ntawm tus neeg mob tus mob, qhov chaw ntawm lub cev cuam tshuam. Hauv cov kab mob hnyav, cov kws kho mob tau sau ib hom kev kho mob plawv siv cov koob tshuaj siab rau lub sijhawm luv luv. Cov kws paub txog qhov tseeb tias cov tshuaj tau hloov kho nyob ntawm tus neeg mob cov lus teb rau kev kho mob.

Txhawm rau ua tiav cov txiaj ntsig kho tau zoo, nws yog qhov yuav tsum tau xaiv qhov kev noj tshuaj Prednisolone. Intramuscularly, cov tshuaj yog siv raws li cov hauv qab no:

  • Nrog rau kev txhim kho ntawm qhov tsis txaus ntawm adrenal tsis txaus, ib koob tshuaj tuaj yeem sib txawv ntawm 110 txog 200 mg. Qhov siab tshaj plaws ntawm 400 mg tuaj yeem muab tau rau ib hnub.
  • Rau qhov ua xua hnyav, cov tshuaj tau muab tshuaj ntawm 200 mg ib hnub rau 18 hnub.
  • Rau mob hawb pob, 500 txog 1200 mg tuaj yeem siv. Maj mam, cov koob tshuaj txhua hnub yuav tsum raug txo kom 300 mg.
  • Nyob rau hauv lub siab mob mobCov tshuaj yog muab rau hauv ib koob ntawm 75 mus rau 100 mg. Kev kho mob kav 10 hnub.

Tom qab teem sijhawm ntawm tus kws kho mob, koj tuaj yeem muab "Prednisolone" intramuscularly rau menyuam yaus. Cov koob tshuaj yog nyob ntawm lub hnub nyoog ntawm tus neeg mob me: los ntawm 2 mus rau 12 lub hlis, 1-2 mg / kg ntawm lub cev hnyav yog siv. Cov tshuaj yog txhaj rau hauv cov leeg gluteal. Los ntawm 1 mus rau 14 xyoo, siv 2 mg / kg. Cov tshuaj yog txhaj tob rau hauv cov leeg rau peb feeb. Yog tias tsim nyog, cov tshuaj tuaj yeem siv dua tom qab 35 feeb.

Kev siv "Prednisolone" rau kev kho cov menyuam yaus
Kev siv "Prednisolone" rau kev kho cov menyuam yaus

kev tawm tsam tsis zoo

Txhawm rau zam kev txhim kho qhov tsis zoo ntawm lub cev rau cov tshuaj, nws yuav tsum tau kawm cov lus qhia rau kev siv "Prednisolone". Intramuscularly, cov tshuaj yog siv nrog ceev faj heev, nws yog txwv tsis pub tshaj li qhov tso cai. Cov kev mob tshwm sim tseem ceeb suav nrog:

  1. Circulatory system: nce ntshav siab, arrhythmia, bradycardia, thrombosis. Kev tuag ntawm myocardial tuaj yeem tshwm sim hauv cov neeg mob uas muaj kab mob plawv.
  2. Kab mob plab: pancreatitis, ntuav, los ntshav sab hauv, xeev siab, tsis qab los noj mov, daim siab lossis lub plab puas tsuaj.
  3. Sensitive organs: thinning ntawm lub cornea, kev puas tsuaj rau lub lens, nce siab nyob rau hauv lub qhov muag.
  4. Daim tawv nqaij: pob txuv tsim, thinning thiab dryness ntawm epithelium, nce pigmentation.
  5. Kev tsis haum: anaphylactic shock, khaus, kub hnyiab, o.
  6. Metabolism: ncua lub ntuj tso dej thiab sodium ntsev los ntawm lub cev, maj mamqhov hnyav nce, poob ntawm cov ntsev muaj txiaj ntsig poov tshuaj.

Cov kws kho mob muaj kev paub dhau los nco ntsoov tias hauv kev kho mob Prednisolone feem ntau siv tshuaj intramuscularly rau kev ua xua. Qhov ntau npaum li cas nyob ntawm tus neeg mob. Tab sis yog tias cov txheej txheem tau ua tsis raug, qhov no yog fraught nrog hlawv, khaus, tingling thiab liab ntawm qhov chaw txhaj tshuaj.

Cov tshuaj tiv thaiv tsis zoo los ntawm "Prednisolone"
Cov tshuaj tiv thaiv tsis zoo los ntawm "Prednisolone"

Qhov tshwm sim ntawm kev noj tshuaj ntau dhau

Yog tias tus neeg mob xav paub yuav ua li cas muab "Prednisolone" intramuscularly, ces tsis muaj teeb meem tshwm sim. Tshaj qhov kev tso cai ntau npaum yog fraught nrog ntau yam deteriorations nyob rau hauv tus mob. Hauv qhov xwm txheej zoo li no, tus neeg mob xav tau kev kho mob sai. Kev noj tshuaj ntau dhau tuaj yeem lees paub los ntawm kev nce hauv peripheral edema, nce ntshav siab. Nws yog ib qho tsim nyog yuav tau hu rau pab neeg mob tsheb thauj neeg mob kom cov kws kho mob tshwj xeeb ntxuav lub plab thiab muab tshuaj kho kom zoo. Hauv tsev, koj tuaj yeem pab tus neeg mob tsuas yog haus dej kom ntau.

Kev siv tshuaj thaum cev xeeb tub thiab pub niam mis

"Prednisolone" tuaj yeem muab rau cov neeg mob zoo li no nkaus xwb vim mob hnyav. Thaum lub sij hawm lactation, nws yuav tsum raug coj mus rau hauv tus account tias cov tshuaj nquag nkag mus rau hauv niam cov kua mis, vim li ntawd nws yog qhov zoo dua kom tsis txhob pub niam mis thiab hloov tus menyuam mus rau cov khoom sib xyaw thaum kho.

Kev siv "Prednisolone" los ntawm cov poj niam cev xeeb tub
Kev siv "Prednisolone" los ntawm cov poj niam cev xeeb tub

Kev rho tawm

Yog tus neeg mob yuav txhaj tshuaj ntev"Prednisolone", ces qhov no yog fraught nrog rau kev quav tshuaj rau lub cev. Cov tshuaj tuaj yeem cuam tshuam rau kev ua haujlwm ntawm tus neeg mob lub qog adrenal. Nrog rau kev txiav txim siab ntawm kev kho mob, tus neeg mob yuav muaj mob hnyav, lub cev kub, thiab qaug zog ntxiv. Tag nrho cov tsos mob no ploj mus ntawm lawv tus kheej yam tsis muaj tshuaj ntxiv. Tab sis yog tias tus neeg mob tau siv ntau npaum li cas ntawm Prednisolone rau lub sijhawm ntev, tom qab ntawd qhov kev tsis pom zoo ntawm cov tshuaj yog fraught nrog qhov teeb meem ntawm hypoadrenal. Nyob rau hauv cov xwm txheej no, cramps ntawm caj npab, vau thiab ntuav tshwm sim. Yog hais tias ib tug neeg tsis tau txais kev pab raws sij hawm, ces lub plawv nres, provoked los ntawm cov hlab plawv insufficiency, yog heev ua tau.

Cov lus qhia tshwj xeeb

Nrog rau kev siv sijhawm ntev ntawm cov tshuaj "Prednisolone", nws yog ib qho tsim nyog yuav tsum tau kuaj xyuas los ntawm tus kws kho qhov muag, kuaj ntshav, saib xyuas lub raum thiab lub siab, thiab tseem xyuas cov ntshav siab. Cov tshuaj yuav tsum tau ua ke nrog cov tshuaj uas txo cov concentration ntawm cov kua txiv hmab txiv ntoo, thiab ua raws li kev noj zaub mov muaj protein ntau.

"Prednisolone" yuav tsum tau siv nrog ceev faj los ntawm cov neeg uas muaj myocardial infarction lossis microstroke. Yog tias kuaj tau kab mob sib kis, ces lawv kuj tau noj cov tshuaj uas txwv tsis pub cov kab mob txaus ntshai.

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Muaj analogues

Yog tus neeg mob muaj contraindications rau kev siv cov tshuaj Prednisolone, ces nws yuav siv tau. Cov tshuaj zoo sib xws nrog lub hauv paus ntsiab lus zoo xws li:

  1. "Triamcinolone".
  2. YBetamethasone.
  3. Flosteron.
  4. Kenalog.
  5. Y"Hydrocortisone".
  6. "Dexamed".
  7. Lemod.
  8. Metipred.
Duab "Hydrocortisone" - analogue ntawm "Prednisolone"
Duab "Hydrocortisone" - analogue ntawm "Prednisolone"

Kev muag khoom thiab cia

Cov tshuaj tsuas tuaj yeem yuav nrog daim ntawv xaj los ntawm koj tus kws kho mob. Koj tuaj yeem khaws cov tshuaj rau ntau tshaj peb xyoos hauv chav tsaus ntawm qhov kub tsis tshaj +27 ° C. Tus nqi nruab nrab ntawm "Prednisolone" hauv kev txhaj tshuaj txawv ntawm 15 txog 20 rubles rau 1 ampoule. Ua ntej siv, koj yuav tsum tau soj ntsuam tag nrho thiab sab laj nrog tus kws kho mob tsim nyog.

Pom zoo: