Atopic dermatitis yog ib yam kab mob uas muaj ntau. Nws tshwm sim vim muaj qhov tshwj xeeb ntawm lub cev tiv thaiv kab mob thiab tsis muaj peev xwm ntawm qee yam proteins hauv daim tawv nqaij. Tus kab mob no yog tus cwj pwm los ntawm qhov siab rhiab heev ntawm daim tawv nqaij mus rau ntau yam ib puag ncig thiab muaj kev nyiam rau kev ua xua. Atopic dermatitis yog tshwm sim los ntawm daim tawv nqaij qhuav, khaus, liab. Txhawm rau tiv thaiv cov tsos mob no, muaj ntau yam tshuaj, ib qho ntawm cov tshuaj pleev Tacropic. Kev tshuaj xyuas txog nws thiab cov lus qhia rau kev siv yog lub ntsiab lus tseem ceeb thiab tseem ceeb rau cov neeg uas muaj kab mob atopic dermatitis thiab tab tom yuav siv lub npe tshuaj.
Tus neeg mob hais dab tsi
Txhua tus neeg uas tau txais daim ntawv xaj los ntawm kws kho mob rau kev yuav khoom ntawm Tacropic, ua ntej ntawm txhua tus pib paub seb lwm tus neeg tau siv cov tshuaj no li cas thiab seb lawv puas tau ntsib kev tsis zoo ntawm lawv tus mob. Tsis muaj kev tshuaj xyuas txaus ntshai txog Tacropic tshuaj pleev. Feem ntau, tib neeg teb zoo rau cov tshuaj. Nws ua haujlwm zoo ntawm daim tawv nqaij. Feem ntau hnub tom qab tom qab thawj zaugsiv, qee cov tsos mob ploj los yog ua tsis tau zoo. Hauv qee tus neeg mob, khaus khaus, o ploj mus. Qhov liab liab tau ploj mus tas li hauv ib lub lis piam.
Muaj qee qhov kev tshuaj xyuas tsis zoo txog Tacropic ointment. Hauv lawv, cov neeg yws yws tias cov tshuaj pleev tsis pab. Txawm li cas los xij, cov kws tshaj lij tau sau tseg tias cov tshuaj pleev tsuas yog siv rau atopic dermatitis. Yog tias muaj lwm yam kab mob, ces txoj kev kho, ntawm chav kawm, yuav tsis pab. Hauv kev tshuaj xyuas tsis zoo, lawv feem ntau sau txog tus nqi siab. Tus nqi kwv yees ntawm cov tshuaj yog los ntawm 550 txog 700 rubles rau ib lub raj txhuas 15 g.
Tsim ntau hom tshuaj pleev thiab muaj pes tsawg leeg
Tam sim no cia peb pib saib cov tshuaj. Ua ntej ntawm tag nrho cov, koj yuav tsum xyuam xim rau qhov tseeb hais tias ntau hom ntawm Tacropic tshuaj pleev yog hais nyob rau hauv kev tshuaj xyuas - nrog 0.03% thiab 0.1% concentration. Cov tshuaj ntawm qhov ntau npaum li cas ntawm 0.03% tsuas yog muab rau cov menyuam yaus hnub nyoog 2 txog 16 xyoo. Rau cov tub ntxhais hluas los ntawm 16 xyoo thiab cov neeg laus, cov kws kho mob tau sau ob qho tib si 0.1% thiab 0.03% tshuaj pleev. Kev kho mob feem ntau pib nrog cov tshuaj muaj zog dua. Nws pab kom ua tiav cov tawv nqaij ib txwm muaj nyob rau hauv qhov txhab. Nrog pom kev txhim kho, lawv hloov mus rau cov tshuaj 0.03%.
Cov tshuaj pleev, tsim los ntawm lub npe "Tacropic", muaj xim dawb lossis yuav luag dawb. Tej zaum nws yuav muaj qhov tsw tshwj xeeb me ntsis. Cov tshuaj pleev muaj xws li ib tug active tshuaj - tacrolimus. Muaj ntau ntau yam ntxiv hauv kev npaj:
- macrogol-400;
- kua paraffin;
- Vaseline dawb mos;
- emulsion ciab;
- disodiumedetat;
- dej huv;
- Euxyl PE 9010 preservative raws li phenoxyethanol.
tshuaj kho mob
Hauv cov lus qhia rau kev siv cov tshuaj pleev Tacropic, pawg kws kho mob tau qhia. Cov tshuaj belongs rau cov tshuaj tiv thaiv kab mob uas npaj rau kev siv tshuaj pleev ib ce.
Cov tshuaj nquag, hu ua tacrolimus, yog calcineurin inhibitor. Nws yog ib qho tshuaj tiv thaiv kab mob siab heev uas inhibits lub cev tiv thaiv kab mob ntawm qib cellular. Tacrolimus, thaum nkag mus rau hauv daim tawv nqaij, inhibits calcineurin, uas ua rau kev ua ntawm T-cell teeb liab. Thaum raug rau cov nquag tivthaiv, qee cov txheej txheem raug thaiv - kev faib cov lymphocytes, tsim cov cytokines, proliferation ntawm beta hlwb. Tsis tas li ntawd, kev tso tawm ntawm cov kab mob inflammatory mediators yog inhibited. Tacrolimus tsis cuam tshuam rau collagen synthesis. Qhov no txhais tau hais tias cov tshuaj tsis ua rau daim tawv nqaij atrophy.
Tacrolimus muaj ntau yam tshuaj noj tshuaj:
- Cov tshuaj tsuas cuam tshuam rau ntawm daim tawv nqaij. Lub active tivthaiv nkag mus rau hauv lub systemic ncig nyob rau hauv tsawg npaum li cas.
- Tacrolimus metabolism hauv daim tawv nqaij tsis ua tiav. Thaum tso tawm rau hauv lub cev, cov txheej txheem no tshwm sim hauv daim siab.
- Lub neej ib nrab ntawm kev rov siv dua yog 65 teev hauv cov menyuam yaus thiab 75 teev rau cov neeg laus.
Nws tsim nyog sau cia tias tacrolimus tau raug cais tawm thawj zaug hauv xyoo 1984 los ntawm cov kws tshawb fawb Nyij Pooj. Ntau qhov kev tshawb fawb tau ua tiav. Lawv cov txiaj ntsig tau ua pov thawj ntawm tus nqi kho mobtshuaj nyob rau hauv kev kho mob ntawm atopic dermatitis. Txawm li cas los xij, kev nyab xeeb ntawm tacrolimus hauv kev siv mus ntev (ntau tshaj ib xyoos) tsis tau kawm. Qee cov kws tshaj lij tau sau tseg tias nrog kev siv ntev ntev muaj peev xwm ntawm kev tiv thaiv kab mob thiab kev loj hlob ntawm oncological formations. Tsis muaj kev tshuaj xyuas txaus ntshai txog cov tshuaj pleev Tacropic ntawm lub ncauj lus no. Txawm li cas los xij, cov teeb meem nrog malignancy, piv txwv li, nrog kev nrhiav tau ntawm cov khoom ntawm cov qog malignant los ntawm cov hlwb, tseem tau sau tseg hauv kev xyaum. Muaj tseeb tiag, cov xwm txheej no raug cais tawm.
Indications thiab contraindications
Atopic dermatitis yog tib qho kev qhia rau kev siv tshuaj pleev Tacropic. Muaj lus piav qhia ntxiv hauv cov lus qhia rau kev siv. Nws cov ntsiab lus - cov cuab yeej no hais txog cov tshuaj thib ob. Cov tshuaj pleev yog muab rau kev kho mob ntawm cov mob nruab nrab thiab hnyav ntawm atopic dermatitis nyob rau hauv rooj plaub uas:
- kab mob tiv taus lwm yam tshuaj;
- tus neeg muaj contraindications rau kev siv lwm yam tshuaj npaj rau kev kho mob ntawm atopic dermatitis.
Tacropic tshuaj pleev yuav tsum tsis txhob siv nyob rau hauv cov ntaub ntawv ntawm hypersensitivity rau lub active thiab auxiliary Cheebtsam. Kuj tseem muaj kev txwv hnub nyoog. Cov neeg uas twb paub txog kev kho mob tsom ntsoov rau ib yam hauv kev tshuaj xyuas: rau cov menyuam yaus, 0.03% tacropic ointment yog contraindicated txog li 2 xyoos, thiab 0.1% tshuaj pleev tsis tuaj yeem siv txog thaum muaj hnub nyoog 16.
Tsis yog npaj rau cev xeeb tub thiab lactation, vim tsis muaj kev tshawb fawb tau ua pov thawjkev nyab xeeb ntawm cov tshuaj rau niam thiab menyuam. Koj tsis tuaj yeem siv cov tshuaj pleev rau lub cev thiab tau txais cov tshuaj tiv thaiv kab mob, thaum noj tshuaj tiv thaiv kab mob. Lwm contraindications yog lub xub ntiag ntawm kev ua txhaum loj ntawm lub epidermal barrier. Cov neeg mob uas muaj qhov teeb meem no yuav muaj kev pheej hmoo ntawm kev nqus ntawm cov khoom xyaw nquag los ntawm kev tsim.
Qee zaum, cov kws tshaj lij pom zoo kom ceev faj thaum siv. Qhov no siv tau rau cov neeg uas tau kuaj pom tias muaj lub siab tsis ua haujlwm, muaj cov kab mob ntawm daim tawv nqaij.
Siv tshuaj pleev rau lub hom phiaj kho
Cov neeg mob paub txog hauv kev tshuaj xyuas ntawm Tacropic ointment tau qhia kom ua raws li cov lus qhia rau kev siv, vim tias qhov no txiav txim siab tsis yog tsuas yog cov txiaj ntsig ntawm cov tshuaj, tab sis kuj muaj kev nyab xeeb. Muaj ob peb txoj kev qhia dav dav:
- Cov chaw cuam tshuam ntawm daim tawv nqaij yuav tsum tau kho nrog tshuaj, siv rau hauv ib txheej nyias. Cov txheej txheem no tuaj yeem ua rau txhua qhov ntawm lub cev rau kev kho mob. Tsuas yog kev zam yog mucous daim nyias nyias. Koj tsis tuaj yeem muab tshuaj pleev rau lawv.
- Tsis txhob siv cov tshuaj nyob rau hauv ib qho kev hnav khaub ncaws, raws li kev tshawb fawb txog kev nyab xeeb tsis tau ua. Cov kws tshaj lij hais tias occlusion tuaj yeem ua rau muaj kev cuam tshuam ntawm cov tshuaj pleev.
Yuav siv cov tshuaj no kom raug thiab ntev npaum li cas? Cov lus teb tshwj xeeb rau lo lus nug no tsis tuaj yeem pom nyob rau hauv kev tshuaj xyuas ntawm Tacropic tshuaj pleev. Cov cai ntawm daim ntawv thov raug txiav txim los ntawm hnub nyoog.
| pab pawg neeg mob | Cov me nyuam hnub nyoog 2 txog 16 |
Cov neeg mob uas koom nrog pawg no tau muab tshuaj pleev 0.03%. Kev kho yog ua nyob rau hauv 2 theem:
|
| Cov menyuam yaus hnub nyoog qis dua 16 xyoo thiab cov neeg laus | Kev kho mob atopic dermatitis pib nrog kev siv 0.1% tshuaj pleev 2 zaug hauv ib hnub. Nrog rau kev txhim kho pom zoo, txo qhov zaus ntawm kev siv cov khoom, lossis hloov mus rau 0.03% tshuaj pleev. | |
| Cov neeg laus (tshaj 65) | Cov neeg laus tsis tau txais kev kho tshwj xeeb. Cov tshuaj pleev yog siv raws li lub tswv yim uas tau muab rau cov menyuam yaus hnub nyoog 16 xyoo thiab cov laus. |
siv tshuaj tiv thaiv kab mob
T. atopic dermatitis yog ib yam kab mob ntev, kev tiv thaiv yog qhov tseem ceeb. Nws tso cai rau koj los txo qhov zaus ntawm exacerbations thiab nce lub sij hawm ntawm remissions. "Tacropic" rau lub hom phiaj ntawm kev tiv thaiv tsis tau sau tseg rau txhua tus neeg. Cov kws kho mob tau sau cov tshuaj no rau cov neeg mob uas muaj tus kab mob hnyav dua 4 zaug hauv ib xyoos (cov neeg laus thiab menyuam yaus hnub nyoog 16 xyoo - 0.1% tshuaj pleev, cov menyuam yaus hnub nyoog 2 txog 16 xyoos - 0.03% tshuaj pleev).
Cov tshuaj tiv thaiv yog siv ntau zaus, raws li pov thawj los ntawm kev tshuaj xyuas ntawm Tacropic ointment. Qhov no tau lees paub hauv cov lus qhia. Cov tshuaj tsuas yog siv xwb2 zaug hauv ib lub lis piam. Hauv qhov no, koj tsis tuaj yeem smear daim tawv nqaij rau 2 hnub ua ke. Yuav tsum muaj qhov sib txawv tsawg kawg 2-3 hnub ntawm daim ntawv thov.
Kuv yuav siv tshuaj qhov twg? Hauv kev tshuaj xyuas ntawm Tacropic tshuaj pleev, tib neeg feem ntau qhia cov ntaub ntawv no. Thaum prophylaxis, cov chaw uas feem ntau cuam tshuam thaum exacerbation ntawm atopic dermatitis yuav tsum tau kho.
Note rau cov neeg mob. Yog tias tus kws kho mob tau muab tshuaj pleev Tacropic rau kev tiv thaiv, qhov no tsis tau txhais hais tias nws yuav tsum tau siv rau yav tom ntej rau tag nrho koj lub neej. Tom qab 12 lub hlis ntawm kev kho mob, nws cov txiaj ntsig tau raug soj ntsuam, kev txiav txim siab tau txiav txim siab los ntawm kev qhia txog kev siv tshuaj tiv thaiv ntxiv.
Side effects
Lub cev ntawm txhua tus neeg yog tus kheej, yog li txhua tus neeg mob zam cov tshuaj pleev tacropic ntau txoj hauv kev rau dermatitis. Hauv kev tshuaj xyuas, tib neeg tham txog cov tsos mob uas lawv tau ntsib vim yog siv tshuaj. Yog tias peb txheeb xyuas tag nrho cov dab neeg tiag tiag, peb tuaj yeem xaus lus tias feem ntau cov neeg mob thaum lub sijhawm siv Tacropic cov tsos mob ntawm daim tawv nqaij khaus. Cov teebmeem tsis zoo raug pom ntawm qhov chaw ntawm kev siv tshuaj. Cov neeg mob yws ntawm khaus, kub hnyiab, mob. Thaum pom ntawm daim tawv nqaij, pob khaus thiab liab yog pom tau. Cov tsos mob ntawm daim tawv nqaij khaus yog feem ntau me me. Tag nrho cov xwm txheej tsis zoo no ploj mus ntawm lawv tus kheej hauv thawj lub lim tiam ntawm kev siv tshuaj.
Cov kev mob tshwm sim muaj xws li kab mob ntawm daim tawv nqaij hauv zos. Thaum khotag nrho cov neeg mob muaj kev pheej hmoo ntawm kev tsim Kaposi tus kab mob herpetic eczema, folliculitis, kab mob provoked los ntawm pathogen Herpes simplex (herpes simplex virus), thiab lwm yam. Hauv kev kho mob, nws paub tias rosacea tshwm sim vim 0.03%, 0.1% Tacropic tshuaj pleev. Hauv kev tshuaj xyuas, cov kws tshaj lij tau sau tseg tias cov no yog cov xwm txheej cais.
Thaum siv tshuaj tsis pom zoo kom haus cawv. Feem ntau, tom qab noj cov dej haus uas muaj cawv, cov neeg mob tig liab, muaj qhov khaus ntawm daim tawv nqaij. Cov teebmeem tsis xav tau no yog cov tsos mob ntawm kev haus dej cawv tsis haum.
Kev Sib Tham Tshuaj
Qhov ib feem ntawm cov tshuaj nquag ntawm cov tshuaj uas nkag mus rau hauv cov kab mob hauv lub cev yog metabolized hauv daim siab raws li kev cuam tshuam ntawm CYP3A4 isoenzyme. Nyob rau hauv txoj kev xav, cov txheej txheem no yuav phem dua yog tias ib tus neeg siv cov tshuaj inhibitors ntawm isoenzyme (xws li erythromycin, ketoconazole). Txawm li cas los xij, hauv kev tshuaj xyuas ntawm Tacropic tshuaj pleev 0.1% thiab 0.03%, cov kws tshaj lij tau sau tseg tias kev cuam tshuam ntawm tacrolimus thiab inhibitors ntawm CYP3A4 isoenzyme tsis zoo li. Nyob rau tib lub sijhawm, nws tsis tsim nyog suav nrog qhov muaj peev xwm ntawm qhov no (tshwj xeeb tshaj yog nyob rau hauv cov neeg uas muaj qhov chaw dav ntawm daim tawv nqaij).
Hmoov tsis zoo, kev tshawb fawb loj tsis tau ua los ntsuas cov txiaj ntsig ntawm Tacropic tshuaj pleev rau qhov ua tau zoo ntawm kev txhaj tshuaj. Vim li no, nws tsis tuaj yeem hais nrog 100% tseeb tias tacrolimus tsis cuam tshuam rau kev ua haujlwm ntawm cov tshuaj tiv thaiv sib txawv. Yuav kom tsis txhob muaj kev phom sij rau tib neeg txoj kev noj qab haus huv, cov kws kho mob tau sau tshuaj tiv thaiv:
- 2 lub lis piam ua ntej pib kho nrog Tacropic ointment lossis tom qab 2lub lis piam tom qab siv lub npe tshuaj kawg;
- 28 hnub ua ntej, lossis 28 hnub tom qab tau txhaj tshuaj tiv thaiv kab mob.
Tsuas muaj cov ntaub ntawv qhia txog kev txhaj tshuaj tiv thaiv kab mob Neisseria meningitidis serotype C. Thaum muab concomitantly nrog tacrolimus hauv cov menyuam yaus hnub nyoog 2 txog 11 xyoo, tsis muaj qhov tsis zoo rau thawj cov lus teb rau kev txhaj tshuaj, cellular thiab humoral tiv thaiv kab mob, tsim kev tiv thaiv kab mob nco.
Tsis muaj dab tsi tuaj yeem hais txog kev siv tib lub sijhawm ntawm Tacropic ointment thiab lwm yam kev npaj sab nraud, cov kab mob glucocorticosteroids, tshuaj tiv thaiv kab mob. Kev sib cuam tshuam ntawm cov tshuaj no tsis tau kawm los ntawm cov kws tshaj lij.
Cov ntaub ntawv ntxiv rau cov neeg mob
Hnub no tsis paub tias cov tshuaj pleev tuaj yeem cuam tshuam qhov rhiab ntawm daim tawv nqaij rau lub teeb ultraviolet. Vim li no, cov kws tshaj lij pom zoo rau cov neeg mob - thaum lub sijhawm kho, tsis txhob raug tshav ntuj, tsis txhob mus ntsib solariums. Tag nrho cov kev ntsuas no raug suav tias yog kev tiv thaiv ntawm photocarcinogenesis (mob qog nqaij hlav ntawm daim tawv nqaij). Tsis tas li ntawd, tsis muaj ib qho twg yuav tsum tau siv tshuaj pleev Tacropic rau cov cheeb tsam uas suav tias yog ua ntej malignant thiab malignant. Yog tias koj tsis quav ntsej cov lus pom zoo no, koj yuav muaj feem yuav mob qog noj ntshav.
Nws tseem ceeb heev kom paub tias:
- Tshuaj pleev yuav tsum tsis txhob nkag rau hauv qhov muag. Txwv tsis pub, lawv yuav tsum tau yaug nrog dej tam sim ntawd.
- Tsis muaj cov ntaub ntawv siv tshuaj ntau dhau nrog kev siv sab nraud.
- Thaum tshuaj ntaussab hauv koj yuav tsum hu rau lub tsheb thauj neeg mob. Ua ntej tuaj txog ntawm cov kws tshaj lij, nws tsis tuaj yeem ua rau ntuav, ntxuav lub plab. Tus neeg mob xav tau kev ntsuas xws li saib xyuas qhov xwm txheej, saib xyuas lub luag haujlwm tseem ceeb ntawm lub cev.
- Cov nyhuv ntawm Tacropic ointment ntawm lub peev xwm tsav ntau yam mechanisms thiab tsheb tsis tau kawm. Txawm li cas los xij, nws tuaj yeem xav tias cov tshuaj tsis muaj qhov tsis zoo, vim tias nws siv sab nraud.
- Tom qab siv cov tshuaj pleev Tacropic (raws li tom qab siv lwm yam tshuaj hauv zos), koj yuav tsum ntxuav koj txhais tes kom huv. Qhov tshwj xeeb yog thaum cov tshuaj siv rau ob txhais tes rau kev siv tshuaj.
Analogues ntawm Tacropic tshuaj pleev
Cov tshuaj no tsis muaj ntau yam analogues. "Protopic" yog suav hais tias yog ib tug ua tiav analogue. Cov tshuaj no muaj nyob rau hauv daim ntawv ntawm cov tshuaj pleev rau sab nraud siv nrog ib tug concentration ntawm 0.1% thiab 0.03%. Cov khoom xyaw nquag yog tacrolimus. Qhov no txhais tau hais tias Protopic ua haujlwm zoo ib yam li Tacropic. Cov tshuaj no muaj tib yam qhia, tib txoj kev ntawm daim ntawv thov, zoo sib xws contraindications thiab phiv. Qhov sib txawv tsuas yog nyob rau hauv cov yam ntxwv ntawm kev tso tawm thiab cov nqi. Cov tshuaj "Protopic", uas yog ib tug analogue ntawm cov tshuaj pleev "Tacropic", nyob rau hauv cov lus qhia rau kev siv hais tias nws muaj nyob rau hauv cov yas raj ntawm 10, 30 thiab 60 g. Tus nqi, ntawm chav kawm, nyob ntawm seb lub ntim thiab npaum li cas.. Piv txwv li, 10 g ntawm tshuaj pleev 0.1% thiab 0.03% nqi ntawm 650 rubles, thiab 30 g ntawm cov tshuaj pleev ib ce 0.1% thiab 0.03% nqi ntawm 1550-1650 rubles.
Tseem muaj qhov nosological analogue ntawm cov tshuaj "Tacropic" - qhov no yog "Elidel". Covcov tshuaj muaj nyob rau hauv daim ntawv ntawm ib tug cream. Cov khoom xyaw nquag yog pimecrolimus. Cov tshuaj no yog ib qho macrolactam derivative ntawm ascomycin. Nws muaj kev ua haujlwm siab anti-inflammatory. Cov tshuaj yog muab rau atopic dermatitis (eczema). Nws tuaj yeem siv tsis yog los ntawm cov neeg laus xwb. Kev kho cov menyuam yaus nrog Elidel cream raug tso cai txij li hnub nyoog 3 hlis. Tus nqi kwv yees li ntawm 850 rubles rau ib lub raj txhuas nrog 15 g ntawm 1% tshuaj.
Atopic dermatitis yog ib yam kab mob loj thiab nyuaj, yog li koj tsis tuaj yeem kho koj tus kheej nrog cov tshuaj sib txawv. Txhua yam tshuaj, suav nrog tus neeg saib xyuas, tuaj yeem ua mob rau tib neeg lub cev yog tias siv tsis raug. Nws kuj tsis pom zoo kom tsom mus rau kev kho mob ntawm cov neeg laus thiab cov menyuam yaus ntawm kev tshuaj xyuas ntawm cov tshuaj pleev Tacropic, txawm tias lawv tau sau los ntawm cov kws tshaj lij. Tsis muaj ib yam dab tsi tuaj yeem hloov qhov kev sib tham tim ntsej tim muag nrog kws kho mob.
