Nyob hauv kab lus, xav txog cov lus qhia rau "Glukobay".
Drug yog ib yam tshuaj ntawm qhov ncauj uas tau siv dav hauv kev kho mob ntshav qab zib. Tus kab mob no yog dab tsi?
Hom 2 mob ntshav qab zib yog ib qho mob insulin-ywj siab.
Hom 2 mob ntshav qab zib yog ib yam kab mob endocrine uas muaj kev ua txhaum ntawm rhiab heev rau kev txiav txim ntawm insulin hauv cov ntaub so ntswg ntawm lub cev. Kev tsim khoom siab ntawm pancreatic β-hlwb provoked los ntawm tus kab mob depletes cov khoom siv ntawm tes, kev tsim cov tshuaj insulin pib poob qis, uas ua rau kev xav tau ntawm nws cov kev txhaj tshuaj. Tus kab mob feem ntau pib tom qab 40 xyoo. Qhov tshwm sim ntawm tus kab mob no tsuas yog tshwm sim los ntawm kev noj qab haus huv ntawm lub neej thiab tsis nyob ntawm cov kab mob caj ces. Cov neeg mob feem ntau muaj qhov ntsuas lub cev hnyav.
Kev faib cov kab mob
Tus kab mob muaj, raws li kev faib thoob ntiaj teb, nws tus kheej cov cai thiab cov lus piav qhia. Tus lej ICD-10 rau hom 2 mob ntshav qab zib yuav yogqhia hauv qab no.
Qhov laj thawj tseem ceeb ntawm cov kab mob no yog rog dhau, yog li cov neeg uas muaj kev pheej hmoo rau qhov teeb meem no yuav tsum saib xyuas lawv cov ntshav qab zib tas li. Cov tsos mob pib:
- tso zis ntau zaus;
- nqhis dej ntau dhau;
- kev tshaib kev nqhis.
Raws li cov cim ntxiv, lawv muaj ntau yam kev hloov pauv hauv lub cev uas tshwm sim vim cov txheej txheem pathological no.
Kev kuaj mob tom qab kuaj mob ntshav qab zib hom 2 (uas, tsis zoo li hom ntshav qab zib hom 1, tsis yog insulin nyob ntawm) muab ntau txoj hauv kev, suav nrog ob qho tib si zaub mov txawv thiab tshuaj noj. Lub hom phiaj tseem ceeb yog nyob rau hauv kev ua neej hloov nyob rau hauv cov nqe lus ntawm kev noj haus. Kev xyaum kho mob qhia tau hais tias txoj kev kho mob no feem ntau muab cov txiaj ntsig zoo, yog tias tus neeg mob ua tiav txhua qhov kev pom zoo hauv kev ntseeg siab.
Cov lej muab yuav tsum tau sau tseg:
- ICD-10 code rau ntshav qab zib hom 2 - E10.
- Non-insulin-dependent diabetes code E11.
- Code E12 piav qhia txog ntshav qab zib vim kev noj zaub mov tsis txaus (hom gestational).
- Code E14 qhia txog txhua yam xwm txheej ntsig txog cov ntaub ntawv tsis tau teev tseg ntawm cov txheej txheem pathological.
tshuaj muaj txiaj ntsig ntawm tshuaj
Raws li cov lus qhia rau Glucobay qhia, cov tshuaj nquag ntawm cov tshuaj no yog acarbose. Cov tshuaj no pab txhawb rau inhibition ntawm cov txheej txheemenzymatic hloov dua siab tshiab ntawm sucrose rau hauv qabzib, uas txo nws cov nqus mus rau hauv cov ntshav los ntawm digestive system.
Glucobay cov tshuaj yog muab los ntawm tus kws kho mob tshwj xeeb thaum noj zaub mov tshwj xeeb tsis tau muab qhov kev xav tau los tiv thaiv ntshav qab zib. Cov khoom siv tshuaj no yog siv los ua tshuaj monotherapy lossis ua ke nrog insulin thiab lwm yam tshuaj.
"Glukobay", kev siv uas suav nrog kev noj zaub mov tshwj xeeb thiab kev ua si lub cev tshwj xeeb, nrog kev siv tsis tu ncua txo qhov tshwm sim ntawm kev tawm tsam ntawm hypo- thiab hyperglycemia, kev pheej hmoo ntawm kev tsim myocardial infarction thiab lwm yam kab mob plawv hauv daim ntawv mob ntev. Cov nyhuv ntawm cov tshuaj nquag ntawm cov tshuaj no yog raws li kev txo qis hauv kev ua haujlwm ntawm alpha-glucosidase thiab kev nqus ntawm cov piam thaj hauv cov hnyuv mus ntev. Yog li, cov tshuaj txo nws cov concentration hauv cov ntshav tom qab noj mov thiab txo cov qib ntawm cov piam thaj hauv ntshav hloov txhua hnub.
Raws li cov lus qhia rau Glucobay, tom qab noj cov tshuaj no, tom qab 1-2 teev, kev txhim kho thawj zaug ntawm acarbose kev ua haujlwm tau sau tseg. Qhov thib ob ncov tshwm sim nyob rau hauv lub sij hawm ntawm 14 mus rau 24 teev. Nws bioavailability sib txawv li ntawm 1-2%. Cov khoom lag luam metabolic ntawm cov kws tshuaj raug tso tawm los ntawm txoj hnyuv - 51% thiab ob lub raum - 35%.
Form and composition
Glucobay ntsiav tshuaj muaj cov tshuaj nquag acarbose ntawm qhov ntau npaum li 100 thiab50 mg ntxiv rau qee cov khoom xyaw ntxiv: colloidal silicon dioxide, magnesium stearate, pob kws starch thiab cellulose.
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm biconvex dawb ntsiav tshuaj nrog ib tug daj tint ntawm ob hom, uas txawv nyob rau hauv cov ntsiab lus ntawm auxiliary thiab active Cheebtsam. Ntawm ib sab ntawm tus dragee, qhov ntau npaum li cas ntawm acarbose yog siv thiab muaj npe nyob rau hauv daim ntawv ntawm "Bayer" ntoo khaub lig nyob rau tom qab.
Glucobay ntsiav tshuaj tau ntim rau hauv cov hlwv ntawm 15 daim thiab hauv cov thawv ntawv. Lub txee lub neej ntawm cov tshuaj yog 5 xyoos.
Indications for prescription
Dab tsi yog qhov qhia tau rau cov tshuaj "Glukobay"? Cov tshuaj no tau sau tseg rau cov neeg mob ntshav qab zib hom 2 ua ke nrog kev noj haus.
Kev noj tshuaj
Raws li cov lus qhia rau Glucobay qhia, cov tshuaj tau noj hauv qhov ncauj, tag nrho, tsis zom, ntxuav nrog dej me me, ua ntej noj mov. Qhov kev pom zoo ntawm cov tshuaj yog xaiv rau txhua tus neeg mob ib leeg.
Feem ntau, koob tshuaj pib yog 1 50mg ntsiav tshuaj lossis ib nrab ntawm 100mg ntsiav tshuaj 3 zaug hauv ib hnub. Qhov nruab nrab koob tshuaj txhua hnub yog 300 mg.
Yog tias qhov kev ua haujlwm tsis txaus ntawm cov kev kho mob zoo li no, tom qab 4-8 lub lis piam ntawm kev kho mob, cov koob tshuaj raug pom zoo kom nce mus rau 200 mg 3 zaug hauv ib hnub. Qhov ntau npaum li cas hauv qhov no yog 600 mg. Hauv cov neeg mob laus (muaj hnub nyoog tshaj 65 xyoos), tsis tas yuav tsum tau hloov cov tshuaj noj lossis tshuaj. Hauv cov neeg uas muaj lub siab ua haujlwm tsis zoo, kho cov txheej txheemkoob tshuaj kuj tsis tsim nyog.
Side effects
Thaum siv cov tshuaj pharmacological "Glucobay", qee qhov kev cuam tshuam tsis zoo yuav tshwm sim. Cov no suav nrog:
- Gastrointestinal: raws plab, flatulence, mob epigastric, xeev siab, nce siab ntawm daim siab enzymes (ntau zaus), uas ploj tom qab tsis siv tshuaj, plab hnyuv, jaundice lossis kab mob siab, nrog rau cov uas cuam tshuam nrog cov kab mob no daim siab cov ntaub so ntswg puas. Muaj cov kab mob sib cais ntawm tus kab mob siab ua rau tuag taus, tab sis kev sib raug zoo ntawm cov xwm txheej zoo li no nrog kev noj cov tshuaj acarbose tsis tau qhia meej.
- Kev ua xua tshwm sim: daim tawv nqaij ua pob khaus, urticaria, hyperemia, exanthema.
- Cov kab mob hauv lub cev: o.
Contraindications rau kev siv
Glucobay tshuaj (analogues yuav tsum tau qhia nyob rau hauv qhov kawg ntawm tsab xov xwm) yog contraindicated nyob rau hauv cov xwm txheej hauv qab no:
- pathologies ntawm lub plab zom mov ntawm lub cev ntawm qhov xwm txheej, tshwm sim nrog qhov tseem ceeb malabsorption ntawm cov as-ham thiab cuam tshuam cov txheej txheem digestive feem ntau;
- kev ua txhaum cai uas tuaj yeem nrog los ntawm qhov tshwm sim ntawm flatulence (loj hernia ntawm ib cheeb tsam, Roemheld's syndrome, peptic ulcer, plab hnyuv obstruction);
- raum tsis ua haujlwm hnyav (nrog QC < 25 ml / min);
- lub sijhawm cev xeeb tub;
- pub mis niam;
- qis dua 18;
- siab rhiab heev rau acarbose lossis lwm yam tshuaj yeeb tshuaj.
Nrog ceev faj, cov tshuaj yog siv rau kub taub hau, kis kab mob, raug mob, kev phais. Txij li thaum asymptomatic nce hauv kev ua haujlwm ntawm hepatic transaminases yog ua tau thaum noj cov tshuaj no, nws raug nquahu kom saib xyuas qhov concentration ntawm cov enzymes hauv cov ntshav thaum thawj 6-12 lub hlis ntawm kev kho mob (raws li txoj cai, cov ntsuas no normalizes thaum cov tshuaj. raug txiav lawm).
Lub hom phiaj thaum cev xeeb tub thiab lactation
Tus kws tshuaj "Glucobay" yuav tsum tsis txhob muab rau cov neeg mob uas tab tom xeeb tub, vim tsis muaj cov ntaub ntawv ntseeg siab ntawm kev siv cov tshuaj no rau cov poj niam cev xeeb tub.
Glucobay tsis pom zoo siv thaum lactation. Yog xav tau tshuaj noj nyob rau lub sijhawm no, yuav tsum tsis txhob pub niam mis ntxiv.
Hauv cov neeg mob uas muaj lub siab tsis zoo thiab lub raum ua haujlwm, tsis tas yuav kho qhov kev siv tshuaj, tshwj tsis yog thaum lub raum tsis ua haujlwm hnyav (nrog rau CC < 25 ml / min).
Special Recommendations
Thaum sau ntawv kho mob Glucobay, qhov yuav tsum tau ua ua ntej yog ua raws li cov cai ntawm kev noj zaub mov noj.
Tus neeg mob ntshav qab zib yuav tsum ceeb toom txog qhov ua tsis tauKev tshem tawm tus kheej ntawm cov tshuaj no, vim qhov no tuaj yeem ua rau muaj kev nce qib ntawm cov piam thaj hauv cov ntshav. Yog tias tus neeg mob tsis ua raws li cov lus pom zoo, tej zaum yuav muaj qhov tshwm sim tsis zoo los ntawm txoj hnyuv. Nyob rau hauv rooj plaub uas kev noj zaub mov nruj me ntsis, tab sis cov tsos mob ntawm cov txheej txheem pathological nce, nws raug nquahu kom txo cov tshuaj noj (rau lub sijhawm ntev lossis luv luv).
Tshuaj "Glukobay" tsis provoke hypoglycemia thaum muab rau cov neeg mob tshwj xeeb nrog kev noj haus. Thaum sib ntxiv ntawm cov khoom siv tshuaj rau kev kho mob nrog insulin lossis tshuaj hypoglycemic qhov ncauj, kev txhim kho ntawm hypoglycemia tuaj yeem raug pom los ntawm kev txo qis hauv kev xav tau rau kev kho mob ntshav qab zib mellitus (qee zaum txawm tias qhov pib ntawm coma, uas yuav xav tau kev kho mob ntshav qab zib mellitus) hloov nyob rau hauv cov tshuaj noj).
Nws yuav tsum raug coj mus rau hauv tus account tias Glucobay nrog acarbose pab ua kom qeeb ntawm kev hloov pauv ntawm sucrose rau hauv qabzib thiab fructose, yog li ntawd, yog tias mob ntshav qab zib mellitus tshwm sim thaum kho nrog cov tshuaj, cov piam thaj yuav tsum tau muab tshuaj kom tshem tawm nws qhov tshwm sim.
Daim npav tus neeg mob sab nraud ntawm tus neeg mob ntshav qab zib yuav tsum nco ntsoov siv cov cuab yeej kho mob.
Cov tshuaj Glucobay, tus nqi uas yuav qhia hauv qab no, tsis cuam tshuam rau lub peev xwm ntawm cov neeg mob los koom nrog kev ua haujlwm txaus ntshai uas xav tau kev saib xyuas ntxiv.
Cov tsos mob ntau dhau
Yog tau txais qhov nonoj tshuaj ntau npaum li cas los yog ib txhij nrog cov khoom noj los yog dej qab zib uas muaj cov carbohydrates ntau (oligo-, di- thiab polysaccharides), cov tsos mob overdose yuav tshwm sim nyob rau hauv daim ntawv ntawm raws plab thiab flatulence. Thaum kho nrog Glucobay, tsis hais txog kev noj zaub mov ntau npaum li cas, qhov tshwm sim ntawm qhov tsis xav tau tshwm sim los ntawm kev zom zaub mov tsis xav tau. Kev kho mob ntau dhau suav nrog tshem tawm cov khoom noj uas muaj carbohydrates los ntawm kev noj zaub mov rau ob peb teev.
Drug interaction
plab hnyuv adsorbents, cholestyramine thiab kev npaj uas muaj cov plab hnyuv enzymes hauv lawv cov muaj pes tsawg leeg tuaj yeem cuam tshuam rau kev ua haujlwm ntawm cov tshuaj Glucobay, yog li lawv siv ua ke tau pom zoo kom zam. Muaj tsawg zaus, cov tshuaj no tuaj yeem cuam tshuam rau bioavailability ntawm digoxin, uas yuav tsum tau hloov kho ntawm cov tshuaj no.
Nws yog ib qho tseem ceeb kom nkag siab tias kev kho mob ntshav qab zib hom 2 ua ke nrog kev noj zaub mov yuav tsum tshwm sim.
Txoj Kev Noj Qab Haus Huv
Nyob rau hauv cov neeg mob ntshav qab zib uas txhob txwm tshaj tawm lossis tsis paub txog tsis ua raws li kev noj zaub mov thaum noj Glucobay, vim tias muaj cov carbohydrates ntau, cov hlwb poob rhiab heev rau insulin. Yog li ntawd, cov piam thaj nce ntxiv. Lub hom phiaj ntawm kev noj zaub mov noj yog txhawm rau kho qhov kev xav tau thiab muaj peev xwm ntawm cov hlwb kom nqus cov piam thaj. Kev noj zaub mov muaj xws li:
- Kev txwv calorie thaum tswj hwm tus nqi zog.
- Noj tib lub sijhawm, uas pab ua kom cov metabolism hauv ib txwm muaj thiab ua haujlwm ntawm lub plab zom mov.
- Yuav tsum tau noj 5-6 pluas noj ib hnub, nrog khoom noj txom ncauj.
- Lub zog tivthaiv ntawm cov zaub mov yuav tsum tau ua raws li kev siv lub zog tiag tiag.
- Kwv yees li tib lub calorie kom tsawg ntawm pluas noj. Feem ntau ntawm cov carbohydrates yuav tsum tau noj hauv thawj ib nrab ntawm hnub.
- Ntxiv cov zaub tshiab uas muaj fiber ntau rau koj noj.
- Hloov cov piam thaj nrog cov khoom qab zib uas tso cai thiab tsis muaj piam thaj hauv qee qhov ntim.
- Noj cov khoom qab zib tshwj xeeb ntawm cov zaub mov tseem ceeb.
- Nyob zoo rau cov khoom qab zib uas muaj roj zaub, vim tias cov rog tawg ua rau qeeb kev nqus ntawm qabzib.
- Yam tsawg kawg ntawm cov carbohydrates yooj yim.
- txwv tsis pub cov carbohydrates yooj yim digestible lossis lawv tsis suav nrog tag nrho.
- Tsiaj tsiaj noj tsawg.
- Kev txo qis lossis tshem tawm ntsev.
- Tsis txhob noj tom qab qoj ib ce lossis kis las.
- No overeating.
- Kev cais lossis txwv tsis pub haus dej ntau.
- Yam tsawg kawg 1.5 litres dej txhua hnub.
- Kev noj zaub mov noj.
- Yuav tsum noj tshais.
- Noj mov kawg yog ob teev ua ntej yuav mus pw.
- Noj zaub mov sov (tsis txias lossis kub dhau).
- Thaum noj movNws raug pom zoo kom noj zaub ua ntej, thiab tom qab ntawd cov zaub mov muaj protein.
Glukobay: price
Tus nqi kwv yees ntawm cov tshuaj yog 370 rubles. Nws nyob ntawm cheeb tsam.
Analogues
Cov npe ntawm Glucobay analogues suav nrog cov tshuaj hauv qab no:
- Glinose;
- Acarbose;
- Siofor.
Tus kws kho mob yuav tsum xaiv qhov hloov pauv.
Reviews about "Glukobay"
Raws li cov ntaub ntawv tau txais los ntawm cov neeg mob cov lus tawm tswv yim ntawm cov tshuaj "Glucobay", cov tshuaj no muaj txiaj ntsig zoo hauv ntshav qab zib mellitus hauv daim ntawv tsis muaj tshuaj insulin. Nws tau txais txiaj ntsig zoo thiab cov kev mob tshwm sim los ntawm kev siv nws tsawg heev.
Raws li kev tshuaj xyuas ntawm cov neeg mob ntshav qab zib mellitus ntawm Glucobay, yog tias koj ua raws li tag nrho cov lus pom zoo ntawm cov kws tshaj lij hais txog kev noj zaub mov noj, koj tuaj yeem txo qis qhov tshwm sim ntawm cov kev mob tshwm sim mus txog qhov ploj mus. Nrog kev noj zaub mov kom zoo, cov tshuaj no txo qis cov tsos mob ntawm tus kab mob hauv qab, txo qhov kev pheej hmoo ntawm qhov tshwm sim tsis zoo uas nws ua rau. Cov neeg mob tau txais kev txaus siab thaum lub sijhawm kho, thiab lawv feem ntau pom cov txiaj ntsig zoo.
Kev tshuaj xyuas txog "Glukobay" lees paub qhov no.
