Nyob rau hauv tsab xov xwm peb yuav xav txog cov tshuaj folic acid txhua hnub. Cov tshuaj no belongs rau qeb ntawm cov vitamins B.
Lub cev ntawm tus neeg noj qab haus huv muaj kwv yees li 5-20 mg ntawm cov khoom no. Ib nrab ntawm cov ntim no yog concentrated nyob rau hauv daim siab. Folic acid tsis khaws cia rau hauv lub cev thiab yuav tsum tau ntxiv txhua hnub. Hauv Russia thiab thoob ntiaj teb, kwv yees li 63-75% ntawm cov poj niam ntsib qhov tsis muaj qhov tseem ceeb no. Tsawg tus neeg paub txog qhov koob tshuaj folic acid txhua hnub.
Vim li cas thiaj tsis txaus
Feem ntau tus mob no yog vim muaj peb lub ntsiab:
- Tsis txaus hauv zaub mov. Nws yuav tsum raug coj mus rau hauv tus account tias thaum lub sij hawm kho cua sov ntawm cov khoom, txog li 90% ntawm cov khoom no muaj nyob rau hauv cov khoom noj nyoos raug puas tsuaj, txawm li cas los xij, xyuas kom muaj qhov ntim txaus.folic acid, uas yog los ntawm cov khoom noj, yog ib qho yooj yim. Ntxiv nrog rau cov nplooj ntawm ntau yam zaub ntsuab, nws kuj muaj nyob rau hauv nqaij, siab, cheese, qe qe, caviar, legumes, txiv lws suav, noob paj noob hlis.
- Xav tau ntau. Qhov kev xav tau ntawm folic acid nce ntxiv thaum, thaum lub sijhawm loj hlob sai thiab cov ntaub so ntswg rov ua dua tshiab: hauv cov tub ntxhais hluas thiab cov menyuam yaus, nrog cov kab mob loj heev, mob ntshav qab zib, kab mob ntawm daim tawv nqaij, thiab lwm yam. mus rau kev loj hlob ntawm fetus. Thaum lub sij hawm lactation, qhov xav tau ntawm cov vitamin no kuj siab heev, nrog rau kev xav tau ntawm lwm cov as-ham.
- Impaired absorption ntawm folic acid nyob rau hauv txoj hnyuv. Cov kab mob ntawm lub plab thiab cov hnyuv tuaj yeem ua rau muaj qhov tsis txaus vim qhov nqus tsis txaus, tab sis nrog kev muaj pes tsawg leeg ntawm microflora ntawm cov plab hnyuv siab raum, lub cev tuaj yeem ua rau nws tus kheej tsim cov folic acid..
Vitamin B9 pom nyob rau hauv cov kws tshuaj yog nqus tau zoo dua li nws cov natural counterparts.
Txoj Cai Ua Haujlwm
Txhua tus paub tias txhawm rau kom cov txheej txheem ntawm kev faib pib hauv lub xovtooj ntawm tes, nws cov khoom siv caj ces, uas yog nyob rau hauv ib lub DNA helix, yuav tsum muab ob npaug rau loj. Nws yog lub sijhawm ua haujlwm no uas folic acid ua lub luag haujlwm tseem ceeb. Nws kuj tseem koom nrog hauv kev sib txuas ntawm RNA, ntau cov amino acids, txhim kho kev nqus hlau. Kev noj tshuaj folic acid txhua hnub thaum cev xeeb tub yuav tsum tau soj ntsuam nruj me ntsis.
Kev tsis txaus ntawm qhov xwm txheej no yog qhov txaus ntshai heev rau cov hlwb uas nquag plias. Folic acid yog tsim nyog rau kev loj hlob thiab kev loj hlob ntawm tag nrho cov ntaub so ntswg.thiab cov kab mob hauv nruab nrog cev, kev tsim ib txwm ntawm embryo, txheej txheem ntawm hematopoiesis. Nyob rau hauv cov theem thaum ntxov ntawm cev xeeb tub, qhov no yog ib qho tseem ceeb heev, txij li thaum twb nyob rau hauv lub thib ob lub lim tiam ntawm lub sij hawm ntawm conception, ib feem ntawm lub paj hlwb tom qab tsim yog twb txiav txim nyob rau hauv lub embryo. Nws yog lub sijhawm zoo li no, txawm hais tias tus poj niam tseem yuav tsis paub txog nws qhov xwm txheej, txawm tias tsis muaj folic acid nyob rau lub sijhawm luv luv tuaj yeem ua rau muaj kev cuam tshuam ntawm cov hlab ntsha hauv cov menyuam hauv plab.
Dhau li ntawm kev koom tes hauv kev tsim cov hlwb, cov vitamin no yog siv los hloov cov hlwb ntawm tus poj niam lub cev thaum cev xeeb tub, vim cov hlwb tau hloov kho tas li. Folic acid koom nrog hauv kev tsim txhua yam ntawm cov ntshav. Nws muab lub siab zoo, koom nrog cov metabolism hauv cov tshuaj lom neeg ntawm adrenaline thiab serotonin, uas cuam tshuam rau kev ua haujlwm ntawm lub paj hlwb, txhawb kev qab los noj mov, thiab koom nrog hauv kev tsim cov hydrochloric acid hauv plab kab noj hniav.
Y Thaum cev xeeb tub, folic acid tsis txaus ua rau muaj kev tsis txaus ntseeg ntawm neural tube anomalies: tsis muaj lub hlwb, hydrocephalus (hydrocephalus), tsim ntawm lub hlwb herniations, spina bifida. Tsis tas li ntawd, malformations ntawm lub plawv thiab cov hlab ntsha thiab kev sib cais ntawm lub palate thiab daim di ncauj (cleft palate, cleft di ncauj) yuav tshwm sim. Nrog rau qhov tsis muaj vitamin B9, kev tsim cov placenta cuam tshuam, qhov tshwm sim ntawm kev rho menyuam tawm, placental abruption, fetal loj hlob retardation, thiab stillbirth nce ntau. Ntau heevKev tshawb fawb tshawb fawb tau pom tias kwv yees li 75% ntawm cov teeb meem no tuaj yeem tiv thaiv yog tias tus poj niam noj folic acid npaj ua ntej xeeb tub.
Thaum pub niam mis, nws yog ib qho tseem ceeb uas yuav tsum tau noj cov tshuaj no ntxiv, txij li thaum lub sijhawm no lub cev xav tau nws ntau tshaj qhov pom thaum cev xeeb tub. Folic acid tsis muaj peev xwm cuam tshuam rau qhov tshwm sim ntawm qhov tsis muaj zog, tsis txaus ntseeg, kev nyuaj siab tom qab yug me nyuam, ua rau txo qis ntawm cov niam cov kua mis, qhov tsis txaus ntawm cov vitamin no hauv tus menyuam. Ntxiv nrog rau ntshav ntshav, cov menyuam yaus uas tsis muaj folic acid tuaj yeem ua rau muaj kev poob qis, kev tiv thaiv tsis zoo, ncua kev puas siab puas ntsws, thiab mob plab hnyuv.
Yog li, koob tshuaj folic acid txhua hnub rau cov poj niam thaum npaj cev xeeb tub yog 4 mg, tom qab xeeb tub, nws maj mam nce mus rau 5 mg, thiab qee zaum 6 mg.
Ib daim foos
Folic acid yog tsim nyob rau hauv cov hmoov thiab ntsiav tshuaj rau kev tswj qhov ncauj ntawm 1 mg (50 thiab 25 daim hauv ib pob). Tsis tas li ntawd, niaj hnub no hauv cov khw muag tshuaj koj tuaj yeem nrhiav cov tshuaj tshwj xeeb rau cov poj niam cev xeeb tub - "Folic Acid 9 Lub Hlis", ib ntsiav tshuaj muaj 4 mg ntawm cov tshuaj no ib zaug - 90, 60 thiab 30 daim ib pob.
koob tshuaj folic acid txhua hnub
Raws li WHO cov lus pom zoo, koob tshuaj txhua hnub ntawm cov tshuaj vitamin no rau cov poj niam txij li lub sijhawm sim xeeb tub mus txog kaum ob lub lis piam ntawm cev xeeb tub yog 4 mg.
Cov poj niam kuaj mobib tug neural tube defect nyob rau hauv lub fetus, raws li zoo raws li cov neeg mob uas twb tau yug los rau cov me nyuam uas muaj xws li ib tug pathological mob nyob rau hauv lub periconceptional lub sij hawm, yuav tsum noj 5 mg ib hnub twg.
Rau lwm haiv neeg, qhov xav tau yog:
- 1-3 xyoos - 1.5mg;
- 4-8 xyoo - 2mg;
- 9-13 xyoo - 3mg;
- 14-18 xyoo - 4 mg.
Dab tsi yog qhov koob tshuaj folic acid txhua hnub rau txiv neej? Cov lus teb yog yooj yim - 4 mg.
Cov ntim tsis txaus tuaj yeem cuam tshuam nrog kev noj zaub mov tsis txaus thiab plab hnyuv thiab kab mob ntev, haus luam yeeb, haus dej cawv thiab plab zom mov.
Qhov siab tshaj plaws ntawm cov tshuaj folic acid yuav tsum tsis pub tshaj 8 mg ib hnub twg.
Cov lus qhia rau kev siv
Ua raws li cov lus qhia rau kev siv, koob tshuaj folic acid txhua hnub hauv mg tau muab rau hauv cov xwm txheej hauv qab no:
- tiv thaiv kev txhim kho ntawm neural tube anomalies hauv fetus thaum thawj peb lub hlis twg ntawm cev xeeb tub;
- folic acid deficiency vim tsis noj zaub mov;
- kho cov tsis muaj chaw sov thiab chaw kub hnyiab (tshwj xeeb hauv plab hnyuv nqus ntawm cov as-ham);
- megaloblastic anemia vim folic acid deficiency;
- leukopenia, tshuaj thiab hluav taws xob anemia;
- plab hnyuv tuberculosis;
- mob plab hnyuv.
Kev siv cov vitamin no thaum cev xeeb tub pab tshem tawm ntau yam teeb meem thaum yug menyuam thiab tom qab yug menyuamkev nyuaj siab.
npe ntawm contraindications
koob tshuaj folic acid txhua hnub thaum npaj cev xeeb tub thiab nqa tus menyuam tsis raug tshuaj rau hauv cov xwm txheej hauv qab no:
- kev nyuaj siab;
- malignant neoplasms;
- pernicious anemia (kev tsis haum ntawm vitamin B12);
- Ecobalamin deficiency;
- hemochromatosis (ua tsis taus hlau metabolism);
- hemosiderosis;
-
noj folic acid txhua hnub thaum npaj
Cov lus qhia rau kev siv
Cia peb saib cov lus qhia rau folic acid rau poj niam, txiv neej thiab menyuam.
Hauv kev kho mob, cov tshuaj hauv qab no ntawm cov vitamin B9 tau siv: nrog nws qhov tsis muaj nyob hauv lub cev - 400 mcg ib hnub; nyob rau hauv kev kho mob ntawm anemia - 3 mg ib hnub twg. Rau kev tiv thaiv, koob tshuaj folic acid txhua hnub rau cov poj niam cev xeeb tub yog raws li hauv qab no: nyob rau hauv thawj peb lub hlis twg ntawm cev xeeb tub los tiv thaiv kev loj hlob ntawm neural tube anomalies - mus txog 800 mcg ib hnub twg; rau kev tiv thaiv ntawm anemia - 1 mg. Folic acid yog noj nrog los yog tom qab noj mov. Lub sijhawm ntawm kev nkag mus kawm feem ntau yog 60 hnub, lub sijhawm ntawm kev kho mob txij li 60 txog 90 hnub.
Rau cov poj niam pub niam mis, qhov xav tau yog 600 micrograms ib hnub. Xav tias folic acid tsis txaus yog qhov txaus ntshai heev hauv thawj lub lis piam tom qab xeeb tub, nws raug nquahu kom noj cov tshuaj vitamin thaum npaj rau nws (tsawg kawg 3 lub hlis), nrog rau tag nrho lub sijhawm yug menyuam.
Ntau npaum li cas folic acidcev xeeb tub yuav tsum tau noj, tam sim no nws yog tseeb. Rau cov hom phiaj kho mob, koob tshuaj rau cov poj niam uas tsis nyob rau theem ntawm kev xeeb tub lossis kev npaj, tuaj yeem nce mus rau 5 mg ib hnub. Kev kho mob feem ntau yog 20-30 hnub. Kev noj tshuaj ntau ntawm cov tshuaj no kuj tau muab rau cov poj niam uas twb muaj xwm txheej nrog kev yug me nyuam nrog folate-dependent kev loj hlob anomalies.
Cov txiv neej laus raug pom zoo kom noj cov tshuaj vitamin B9 - 4 mg ib hnub twg.
Side effects
Vim li cas nws tseem ceeb kom tswj tau cov tshuaj folic acid txhua hnub? Kev noj tshuaj hauv qee kis tuaj yeem ua rau muaj kab mob hauv qab no:
- nausea;
- iab hauv qhov ncauj;
- flatulence;
- tshuaj tsis haum - khaus, tawv nqaij pob, erythema, bronchospasm, hyperthermia.
Yog tias noj tshuaj ntau dhau ntawm cov vitamin no, hypovitaminosis B9 tuaj yeem txhim kho.
User kev nyab xeeb
haus folic acid ntau npaum li cas, nws tseem ceeb kom paub ua ntej.
Cov tshuaj no tsis muaj tshuaj lom rau tib neeg. Cov kev tshawb fawb tau tshawb fawb txog kev siv ntev ntev ntawm 15 mg ntawm folic acid nyob rau ib hnub (ntau tshaj qhov ntau npaum li 40 zaug), uas tsis tau qhia txog cov tshuaj lom los ntawm kev noj cov tshuaj no. Txawm li cas los xij, kev siv sijhawm ntev (ntau tshaj 3 lub hlis) ntawm cov koob tshuaj ntau tuaj yeem txo qhov concentration ntawm vitamin B12 hauv cov ntshav, uas tuaj yeem ua rau muaj kev loj hlob ntawm cov ntshav liab. Kev siv tshuaj ntau dhau qee zaum ua rau muaj kev cuam tshuam ntawm lub plab zom mov, kev ua haujlwm tsis zoo hauv kev ua haujlwmob lub raum, nce kev puas siab puas ntsws excitability.
Nws yog ib qho tseem ceeb kom noj cov vitamin B9 tsis tu ncua. Tab sis muab qhov tseeb tias txhua yam tshuaj yuav them rau koj qhov kev xav tau folic acid txhua hnub, tsis txhob txhawj yog tias koj tsis nco lwm koob.
Kev Sib Tham Tshuaj
Ntau yam tshuaj tuaj yeem cuam tshuam rau kev nqus, siv thiab khaws cia ntawm folic acid hauv lub cev. Cov tshuaj raws li cov tshuaj no yog qhov zoo tshaj plaws noj ib txhij nrog cov vitamins C thiab B12. Kev siv ntxiv ntawm bifidobacteria tuaj yeem txhim kho cov txheej txheem ntawm folic acid synthesis hauv lumen ntawm txoj hnyuv loj. Thaum noj cov dej haus cawv, cov tshuaj antacids (cov tshuaj uas ua kom tsis muaj zog hydrochloric acid - Maalox, Almagel, thiab lwm yam), nrog rau cov tshuaj tiv thaiv kab mob thiab sulfonamides, kev nqus ntawm cov vitamin B9 hauv txoj hnyuv tau txo qis. Ib txhij siv tshuaj "Aspirin" hauv koob tshuaj ntau, cov tshuaj nitrofuran uas tau sau tseg rau cov kab mob sib kis ntawm cov kab mob urinary, cov tshuaj hormones corticosteroid thiab cov tshuaj tiv thaiv qhov ncauj pab txo qis cov folic acid hauv cov ntshav.
Signs of deficiency
Cov tsos mob tseem ceeb ntawm kev tsis txaus yog:
- poob kev txaus siab hauv lub neej, tsis txaus siab;
- txo qis hauv kev ua haujlwm thiab kev ua haujlwm;
- kev ua phem thiab chim siab;
- qhov tshwm sim ntawm ntau yam phobias thiab manias;
- overwork;
- pw tsis tsaug zog;
- tsis nco qab thiab mloog;
- ntau zauskev loj hlob ntawm mob taub hau;
- poob ceeb thawj;
- plab hnyuv;
- psoriasis;
- ntshav qab zib;
- pob txuv.
Ntxiv rau cov tsos mob saum toj no ntawm vitamin B9 tsis txaus, cov poj niam yuav muaj kev cuam tshuam ntawm cov plaub hau, rau tes thiab tawv nqaij, kev loj hlob ntawm cov plaub hau grey ua ntej. Tsis tas li ntawd, lawv muaj teeb meem ntau yam kev hloov hormonal thaum lub sij hawm cev xeeb tub.
Txij li thaum folic acid yog lub luag haujlwm rau kev tsim ntau lub cev, carbohydrate thiab rog metabolism, nws qhov tsis txaus ntawm cov menyuam yaus tuaj yeem ua rau kev loj hlob tsis zoo. Yog li ntawd, nyob rau theem ntawm kev loj hlob nquag, cov niam txiv yuav tsum ua tib zoo saib xyuas tus menyuam txoj kev noj zaub mov thiab, yog tias tsim nyog, hu rau tus kws kho mob tshwj xeeb rau kev teem sijhawm cov tshuaj uas muaj cov vitamin no. Yog tias tus menyuam muaj qhov tsis muaj zog, tsis txaus siab, tsis qab los noj mov - cov no yog thawj cov cim qhia tias tsis muaj folic acid.
Qhov xav tau ceev tshaj plaws rau cov vitamin B9 yog cov menyuam yaus hnub nyoog kawm ntawv thiab cov tub ntxhais hluas, uas cov tshuaj hormones hloov pauv hauv lub cev txij li hnub nyoog 14 xyoos. Cov cim tseem ceeb ntawm cov vitamin tsis txaus nyob rau hauv cov tub ntxhais hluas yog suav tias yog: poob ntawm qhov tseem ceeb, tsis tsim nyog lub paj hlwb, pw tsaug zog, nquag plab zom mov, teeb meem kev ua haujlwm hauv tsev kawm ntawv, ntau yam pob khaus thiab liab ntawm daim tawv nqaij, thaum tsis muaj caj ces predisposition - cov plaub hau grey thaum ntxov. Folic acid tseem ceeb heev rau cov tub ntxhais hluas thaum lub hnub nyoog laus, vim tias qhov tsis txaus ntawm cov vitamin no yav tom ntej.tuaj yeem ua rau cov kab mob pathological ntawm cov menyuam yaus. Folic acid deficiency feem ntau tshwm sim vim kev noj zaub mov tsis zoo, yog tias tus hluas noj zaub mov muaj me me ntawm cov txiv hmab txiv ntoo tshiab thiab zaub. Nrog qee qhov pathologies ntawm lub plab zom mov, cov teeb meem zoo sib xws kuj tuaj yeem tshwm sim. Qhov ntau npaum li cas ntawm cov tshuaj yog xam nyob rau hauv tus kheej lub hauv paus, uas yog nyob ntawm lub hnub nyoog ntawm tus me nyuam thiab indications. Cov tub ntxhais hluas raug pom zoo kom noj cov tshuaj vitamin ntawm 150-200 mcg.
Cov neeg uas koom nrog kev ua kis las tuaj yeem ntsib tag nrho cov cim saum toj no ntawm kev tsis txaus ntawm cov khoom no, uas muaj nyob rau hauv cov neeg laus ib txwm muaj, tab sis tej zaum yuav hais tau ntau dua thiab tshwm sim ntau zaus. Qhov no yog vim lub fact tias thaum lub sij hawm lub cev muaj zog exertion muaj ib tug loj noj ntawm cov tshuaj, yog li ntawd cov neeg ncaws pob tsuas yuav tsum tau ntxiv nws.
Peb saib seb qhov koob tshuaj folic acid yog dab tsi txhua hnub.
