Tsis sib xws rau nws lub npe, nicotinic acid yuav luag tsis muaj dab tsi cuam tshuam nrog kev haus luam yeeb nicotine. Thawj yog pab tau rau tib neeg, thiab qhov thib ob yog cov tshuaj lom txaus ntshai, alkaloid. Txhawm rau kom tsis txhob muaj kev ntxhov siab hauv cov ntsiab lus, cia li hais tias nicotinic acid tseem hu ua "niacin", lossis vitamin PP. Cov tshuaj no ua lub luag haujlwm li cas hauv lub cev, tshuaj xyuas ntawm nicotinic acid, nws siv hauv tshuaj, cosmetology thiab kev ua kis las - koj tuaj yeem nyeem hauv qab no.
Yuav ua li cas, los ntawm leej twg thiab yog vim li cas thiaj nrhiav tau niacin
Rau ntau pua xyoo, hauv cov tebchaws uas lub hauv paus ntawm kev noj haus yog pob kws nplej (Ltalis, Spain, Argentina), cov neeg raug kev txom nyem los ntawm pellagra. Txog niaj hnub no, cov kws tshawb fawb tau tswj xyuas yuav luag tag nrho cov kab mob no. Funk thiab Goldberger tau txais txiaj ntsig zoo rau kev kawm txog qhov ua rau pellagra. Lawv tau lees paub tias muaj qee yam khoom, uasua rau neeg mob. Tsis tas li ntawd, xyoo 1914, R. N. Funk tau pom tias pellagra raug kev txom nyem los ntawm cov neeg pluag, uas nws cov khoom noj muaj ntau cov pob kws, tab sis yuav luag tsis muaj mis nyuj, nqaij, thiab qe. Nws tau pom tseeb tias feem ntau cov neeg tau mob, nyob rau hauv cov khoom noj uas tsis txaus ntawm ib qho kev tivthaiv.
Xyoo 1937, nicotinic acid yog thawj zaug ua ke hauv chav kuaj. Txij thaum ntawd los, ntau lub sijhawm tau dhau mus thiab niaj hnub no cov niacin ib txwm tuaj yeem yuav ntawm txhua lub tsev muag tshuaj.
Nicotinic acid yog tshuaj rau dab tsi?
Cov kws kho mob tau sau ib chav kawm ntawm vitamin PP rau cov kab mob hauv qab no:
- kab mob ntev ntawm daim siab thiab lub zais zis (cirrhosis, kab mob siab ntawm ntau yam etiologies, cholecystitis, cholestasis, rog thiab lwm yam hepatoses);
- osteoarthritis;
- kev tiv thaiv thiab kev kho mob ntawm pellagra;
- osteochondrosis ntawm lub ncauj tsev menyuam, thoracic lossis lumbar qaum;
- kab mob neurodegenerative (xws li Alzheimer's disease);
- psoriasis, atopic dermatitis, pob txuv thiab lwm yam kab mob ntawm daim tawv nqaij;
- kev tswj ntshav qab zib (tseem ceeb rau cov neeg mob ntshav qab zib hom 1 thiab hom 2);
- ua txhaum ntawm lipid metabolism thiab rog - kom nrawm metabolism;
- tuav cov txheej txheem metabolic hauv cov hlwb ntawm tag nrho cov kabmob;
- alopecia (hair poob) ntawm ib qho etiology.
Niacin muaj nyob rau hauv 3 daim ntawv:
- nicotinic acid,
- nositol hexaniacinate.
Ncotinamide Ncotinamide
Nicotine muajacid nyob rau hauv cov ntsiav tshuaj thiab ampoules rau intramuscular txhaj. Koj tuaj yeem yuav ntawm txhua lub tsev muag tshuaj, tus nqi qis - txog 100 rubles ib pob nrog tag nrho cov chav kawm ntawm cov tshuaj. Cov txheej txheem ntawm kev tswj hwm ntawm nicotinic acid (qhov ncauj lossis hauv daim ntawv txhaj tshuaj) nyob ntawm tus kheej nyiam ntawm tus neeg mob. Ntau tus neeg laus tseem ntshai kev txhaj tshuaj, yog li lawv feem ntau nyiam cov ntsiav tshuaj daim ntawv (uas, los ntawm txoj kev, muaj tshuaj lom ntau rau lub siab).
Nicotinic acid belongs rau cov npe tshuaj rau kev yuav khoom uas tsis tas yuav tsum muaj daim ntawv xaj. Txawm li cas los xij, tseem zoo dua tsis txhob kho tus kheej.
Vim li cas cov kua qaub no hu ua nicotinic acid?
Niacin tuaj yeem hu sib txawv thiab ib qho ntawm cov npe no yuav txhais tau tib yam tshuaj:
- nicotinic acid;
- Yvitamin PP;
- Vitamin B3.
Cov kua qaub no yog ib yam tshuaj (tsis zoo li lwm cov vitamins B) thiab koom nrog hauv cov txheej txheem metabolic.
Nicotinic acid thiab nicotine yog cov khoom sib txawv kiag li nrog cov qauv molecular sib txawv. Nicotine yog tshuaj lom, alkaloid, thaum nicotinic acid yog vitamin.
Lub npe PP txhais tau tias "tiv thaiv pellagric". Cov tshuaj no tuaj yeem kho tus kab mob hu ua pellagra sai sai (ib yam ntawm beriberi, nicotinic acid deficiency).
Side effects
Tsis txhob hnov qab tias leej twgCov tshuaj muaj contraindications. Yog tias koj tsis ua raws li cov lus qhia pom zoo rau nicotinic acid, ces cov kev mob tshwm sim hauv qab no yuav tshwm sim:
- daim tawv nqaij khaus, liab, tingling ntawm tes, dab teg, forearms, ntsej muag, caj dab, pob ntseg, sab nraub qaum (qhov no yog vim cov ntshav ntws mus rau lub cev sab sauv);
- xeev siab (tshwm sim thaum qhov pom zoo noj ntau dhau lawm);
- mob taub hau thiab kiv taub hau (tsuas yog tshwm sim hauv cov neeg uas ua rau mob migraines);
- ua kom lub zais zis tsis zoo, txhawb kev tsim cov roj (cholesterol) phem;
- nce ntshav AST, LDH, tag nrho bilirubin;
- Nyob rau hauv cov neeg mob ntshav qab zib, niacin tuaj yeem ua rau cov ntshav qab zib nce ntxiv.
Txhawm rau tiv thaiv cov kev mob tshwm sim, koj yuav tsum ua raws li cov lus qhia rau nicotinic acid. Cov kev xav tau niaj hnub rau vitamin B3 rau cov poj niam cev xeeb tub thiab lactating cov poj niam: 19-21 mg, rau cov neeg laus: 25 mg, rau lub cev hnyav: 30 mg, rau cov menyuam hnub nyoog 1.5 txog 7 xyoo - 5 mg; los ntawm 7 mus rau 13 xyoo - 10 mg; rau cov tub hluas hnub nyoog 14-19 - 21 mg; rau cov ntxhais hnub nyoog 14-19 - 20 mg.
Ceev faj yuav tsum tau siv rau hauv cov neeg mob hemorrhages, mob ntshav siab heev, glaucoma, siab thiab raum tsis ua haujlwm, peptic ulcer ntawm lub plab thiab duodenum.
Nyob rau lub siab
Nyob rau hauv cov koob tshuaj me me, vitamin B3 tsuas tuaj yeem nqa cov txiaj ntsig. Txawm li cas los xij, yog tias tus neeg mob muaj keeb kwm muaj kab mob siab ntev, nws tsim nyog noj nicotinic acid nrog ceev faj heev. Nws tseem ua rau kev txiav txim siab txo nws qhov noj rau 10 mg ib hnub.
Qhov tseeb yog tias nicotinic acid tau siv ntev los kho cov roj cholesterol thiab triglycerides hauv cov ntshav. Ib yam li statins, Vitamin B3 tuaj yeem ua rau lub siab tsis zoo. Nicotinic acid nyob rau qee kis ua rau muaj kev nce qib ntawm asparagine transferase thiab alanine transferase, uas nyob rau qee kis nrog cov tsos mob ntawm tus kab mob jaundice, nce siab ntawm daim siab, thiab qee zaus txawm tias mob siab tsis ua haujlwm.
Cov tshuaj lom rau lub siab ntawm nicotinic acid nyob ntawm txoj kev tswj hwm (intramuscularly lossis qhov ncauj) thiab ntawm koob tshuaj. Cov tshuaj lom neeg pib ntawm 1-1.5 grams tauj ib hnub. Cov neeg uas muaj kab mob siab ntev yuav muaj kev pheej hmoo ntawm kev tsim cov tshuaj lom uas tsis tuaj yeem hloov pauv hauv kev siv tshuaj ntau dhau.
Nws puas tuaj yeem ua kom cov plaub hau loj hlob siv niacin?
Yuav ua li cas cov ntxhais tsis tuaj yeem xav txog hauv kev sib ntaus rau cov plaub hau zoo nkauj. Ob peb xyoos dhau los, Lub Network tau muaj tag nrho ntawm "kev tshuaj xyuas txuj ci tseem ceeb" txog nicotinic acid, uas tau thov tias tom qab kawm ntawm cov vitamin no, lawv cov plaub hau pib loj hlob zoo li tsis tau ua dhau los.
Hauv tshuaj, cov xwm txheej zoo li no tau sau npe tiag tiag. Nicotinic acid dilates cov hlab ntsha txawm tias thaum siv rau ntawm tawv taub hau - vim qhov no, cov nyhuv ntawm stimulating cov plaub hau follicles yog tiav. Tab sis qhov ceev ntawm cov plaub hau kev loj hlob yog txwv los ntawm physiology: txawm yuav nyuaj npaum li cas los xij, txawm koj rub rau hauv cov hauv paus hniav, nws tsuas yog tsis yooj yim sua kom ceev cov plaub hau loj hlob ntau tshaj peb centimeters ib hlis.
Ntau tus ntxhais zoo siab ntxiv cov vitamin ampoule rau lub ntsej muag tsis tu ncua. Qhov no txhawb cov plaub hau kev loj hlob, pab ntxiv dag zog rau lawv. Kev tshuaj xyuas txog nicotinic acid rau cov plaub hau feem ntau zoo siab, cov nyhuv ntawm nws yog qhov zoo rau alopecia.
Cov neeg ncaws pob siv nicotinic acid li cas?
Kev siv niacin hauv kev tsim lub cev yog qhov ncaj ncees. Vitamin PP ua kom cov metabolism sai (uas ua rau muaj roj hlawv thiab cov leeg txhais), txhim kho cov ntshav ncig, thiab, nrog rau kev noj zaub mov kom zoo, nce anabolism.
Nws yog qhov tsim nyog los noj tshuaj ntau ntawm niacin thaum lub sijhawm "qhuav" hauv cov kis las. Cov lipid-txo cov nyhuv ntawm nicotinic acid pab txhawb thiab ua kom cov txheej txheem ntawm cov rog hlawv, thauj cov khoom lwj ntawm cov rog rog kom tshem tawm ntawm lub cev.
Nicotinic acid hauv cosmetology
Ntau tus poj niam nyiam ntxiv niacin rau lub qhov ncauj qhov ntswg thiab tshuaj pleev hauv tsev. Vim cov ntshav ntws, lub complexion txhim kho, me ntsis blush tshwm, lub pores zoo dua cleansed. Cov nplaum nplaum nplaum nplaum nplaum nrog qhov sib ntxiv ntawm ib qho kev poob ntawm nicotinic acid yog nrov. Cov lus teb rau cov txheej txheem no tsuas yog qhov zoo. Tom qab sib tov xws li daim npog qhov ncauj rau ib homogeneous sib xws, nws yog tsim nyog los thov nws nyob rau hauv ib tug nyias txheej ntawm daim tawv nqaij ntawm lub ntsej muag thiab tawm rau 10-15 feeb. Yog li ntawd, lub complexion yog evened, lub pores yog cleared.
Tab sis kev siv zoo tshaj plaws ntawm nicotinic acid yog nyob rau hauv mesotherapy. Salon mesococktails los ntawm cellulite, yuav luag tag nrho cov muaj niacin nyob rau hauv lawv muaj pes tsawg leeg. Tau kawg, asauxiliary tivthaiv. Hauv tsev, nws tsis tuaj yeem ua kom zoo mesotherapy rau koj tus kheej, yog li ntawd, kev siv tshuaj pleev ib ce ntawm nicotinic acid tsuas yog ntxiv rau lub ntsej muag thiab plaub hau qhov ncauj qhov ntswg.
YIntramuscular Administration
Cov tshuaj yog tsim tsis tsuas yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, tab sis kuj nyob rau hauv daim ntawv ntawm ib tug 1% txhaj tshuaj nyob rau hauv 1 ml ampoules. Nrog rau kev tswj hwm intramuscular ntawm nicotinic acid nyob rau hauv ampoules, qhov kev pheej hmoo ntawm cov teeb meem ntawm cov zis thiab lub siab yog txo, txawm nyob rau hauv cov koob tshuaj ntau. Txoj kev tswj hwm no zoo dua thiab muaj kev nyab xeeb dua li kev noj tshuaj.
Neurologists pom zoo kom muab cov tshuaj nicotinic acid nrog kev txhaj tshuaj ntawm lwm cov vitamins B (thiamine, pyridoxine, cyanocobalamin, riboflavin). Cov chav kawm zoo li no muaj txiaj ntsig zoo rau lub xeev ntawm lub paj hlwb, txo qhov mob hauv osteochondrosis thiab mob caj dab.
Nicotinic acid hauv ampoules yog pheej yig - txog 100 rubles ib pob, uas 10 vials. Koj tuaj yeem xaiv cov chaw tsim khoom rau koj saj ("Nikospan", "Enduracin", "Vial", "Moskhimfarmpreparaty") - lawv xyaum tsis txawv qhov zoo thiab tus nqi.
Puas yog rau kuv tus kheej, hauv tsev, txhawm rau txhawm rau txhaj tshuaj nicotinic acid? Yog, nws muaj kev nyab xeeb heev. Nws yog qhov zoo dua los cob qhia koj tus kheej kom muab tshuaj nyob rau hauv kev saib xyuas ntawm tus kws saib xyuas neeg mob - nws yuav qhia yuav ua li cas tsis txhob kov cov hlab ntsha thaum lub koob txhaj tshuaj thiab kom tsis txhob muaj qhov nqaij tawv tom qab txhaj tshuaj.
Nicotinic acid ntsiav tshuaj
ReceptionQhov ncauj tuaj yeem ua rau muaj kev cuam tshuam ntau ntxiv - khaus thiab liab ntawm lub cev. Qhov no yog qhov hu ua hyperemia: tingling thiab kub hnyiab, liab ntawm daim tawv nqaij. Tus mob no feem ntau daws tau li ntawm ib nrab teev tom qab noj tshuaj.
Kom txo qhov khaus khaus, cov kws kho mob pom zoo kom noj cov tshuaj tam sim tom qab noj mov, assimilation nrog zaub mov yooj yim dua thiab sai dua.
Nicotinic acid tshuaj xyuas feem ntau ua rau cov kev mob tshwm sim no. Qhov tseeb, tsis muaj dab tsi tsis ncaj ncees lawm, thiab nws tsis ua rau muaj kev phom sij rau lub cev, ntawm qhov tsis sib xws, nws qhia tau hais tias cov hlab ntsha zoo.
Vim li cas nicotinic acid tau sau hauv cov ntsiav tshuaj? Cov lus qhia zoo ib yam li kev txhaj tshuaj intramuscular, tab sis ntau tus neeg ntshai ntawm kev txhaj tshuaj thiab nyiam cov tshuaj ntsiav.
Natural sources of nicotinic acid
Nws tsis tas yuav nqos cov tshuaj lossis txhaj tshuaj, koj tuaj yeem kho koj cov zaub mov thiab qhia txog cov khoom noj txhua hnub xws li:
- unroasted nuts: txiv laum huab xeeb, pistachios;
- txuj lom: turmeric, nutmeg, coriander;
- zaub cob pob;
- rice and rye bran;
- nyuaj ntuj cheese;
- Nyob qaib qus.
Tsis tas li, nicotinic acid tuaj yeem ua rau tib neeg lub cev ntawm nws tus kheej los ntawm cov amino acid tryptophan. Uas nyob rau hauv lem muaj nyob rau hauv nyuaj cheese thiab khoom noj siv mis. Yog li tsis muaj teeb meemTxawm tias koj noj tshuaj, koj yuav tsum noj tag nrho thiab ntau yam.
Nicotinic acid thiab lwm cov vitamins - Kuv puas tuaj yeem ua ke?
Niacin yuav tsum raug ua ke nrog thiamine, pyridoxine thiab magnesium npaj. Ua antagonists, cov khoom no tsis ua rau ib leeg ua. Kev sib raug zoo ntawm nicotinic acid nrog ntau cov vitamins yog questionable.
Piv txwv li, cov tshuaj nrov "Magne B6" vim muaj cov ntsiab lus siab ntawm pyridoxine muffles cov nyhuv ntawm niacin. Kev tshuaj xyuas, txawm li cas los xij, tseem muaj txiaj ntsig zoo, vim tias cov neeg mob feem ntau tsis muaj magnesium. Vim li ntawd, qee qhov ntawm cov khoom tseem nqus tau, txawm tias tsis tag.
Thaum siv tshuaj intramuscularly, cov vitamins B thiab niacin yuav tsum sib cais. Piv txwv li, thaum sawv ntxov los txhaj tshuaj nicotinic acid thiab cyanocobalamin. Thiab thaum yav tsaus ntuj - thiamine, pyridoxine thiab riboflavin.
