Epinephrine - yog dab tsi? Peb yuav tham txog qhov no hauv tsab xov xwm nthuav tawm. Koj tseem yuav kawm txog lub hom phiaj uas cov tshuaj tau hais los siv, seb nws puas muaj contraindications thiab phiv.
tshuaj muaj zog
Epinephrine - yog dab tsi? Cov khoom no yog dab tsi? Raws li cov kws tshaj lij, qhov no yog ib qho tseem ceeb tshaj plaws neurotransmitters uas yog tsim los ntawm cov qog adrenal. Lwm lub npe rau lub caij no yog adrenaline.
Raws li cov qauv tshuaj, cov khoom hauv nqe lus nug belongs rau catecholamines. Yog li, epinephrine yog ib qho hluavtaws adrenaline.
Nyob rau hauv lub cev ib txwm muaj, qhov sib xyaw no muaj nyob rau hauv ntau yam kabmob thiab cov ntaub so ntswg. Nws yog tsim los ntawm chromaffin ntaub.
Epinephrine, cov lus qhia rau kev siv uas tau nthuav tawm hauv qab no, muaj kev cuam tshuam rau beta- thiab alpha-adrenergic receptors, thiab tseem ua kom muaj kev zoo siab ntawm cov paj hlwb paj hlwb.
Nrog kev ntxhov siab, kev paub txog kev phom sij, kev ntxhov siab, ntshai, kub hnyiab thiab ntau yam kev raug mob, qhov concentration ntawm adrenaline hauv lub cev nce ntau. Nws koom nrog hauv txhua hom metabolism, thiabcuam tshuam rau qib qabzib thiab cov ntaub so ntswg metabolism, txhim kho gluconeogenesis, glycogenolysis, protein catabolism thiab rog rog, inhibits glycogen synthesis hauv cov leeg nqaij thiab daim siab.
Ib daim foos
Epinephrine: nws yog dab tsi thiab nws tsim nyob rau hauv daim ntawv dab tsi? Muaj ntau hom kev tso tawm ntawm epinephrine. Nws yog muag raws li tee lossis homeopathic granules rau kev tswj qhov ncauj, nrog rau cov kev daws teeb meem rau kev txhaj tshuaj thiab tshuaj pleev. Tsis tas li ntawd, cov tshuaj no yog tsim nyob rau hauv daim ntawv ntawm ib tug tincture los yog ib tug hmoov.
tshuaj muaj txiaj ntsig
Dab tsi yog cov tshuaj epinephrine muaj? Nws yog dab tsi, peb hais saum toj no. Raws li cov kws tshaj lij, cov tshuaj no muaj hyperglycemic, hypertensive, vasoconstrictive, bronchodilator thiab antiallergic teebmeem.
Synthetic adrenaline ntawm qib cellular activates lub enzyme adenylate cyclase, tsub kom cov concentration ntawm cAMP thiab calcium ions. Cov tshuaj no ua rau kom ntshav siab, constricts cov hlab ntsha ntawm lub hauv nruab nrog cev, daim tawv nqaij, mucous daim nyias nyias, skeletal nqaij, thiab kuj dilates cov hlab ntsha ntawm lub hlwb.
khoom nta
Epinephrine hydrochloride relaxes cov leeg ntawm cov hnyuv thiab bronchi. Tsis tas li ntawd, nws ua rau cov menyuam kawm ntawv dilation.
Kev siv tshuaj nrog cov tshuaj no ua rau lub plawv xav tau oxygen thiab tiv thaiv kev txhim kho ntawm o ntawm bronchioles. Tsis tas li ntawd, cov tshuaj no txo qis tus nqi ntawm kev nqus ntawm cov tshuaj loog hauv zos, txo cov tshuaj toxicity thiab nce lub sijhawm ntawm kev ua ntawm cov tshuaj npaj rautshuaj loog hauv zos.
Kev qhia
Dab tsi yog epinephrine siv rau? Kev siv cov khoom no yog qhia rau kev kho mob ntawm cov tshuaj tiv thaiv tam sim ntawd uas tau tsim los ntawm kev siv ntshav, tshuaj raug, kev siv ntau yam khoom, tom qab kab tom los yog qhia txog kev ua xua.
Kuj hais txog cov tshuaj no yog siv rau hauv qab no:
- rau kev pab ntawm bronchial hawb pob tawm tsam;
- nrog asystole;
- kom ncua qhov kev ua ntawm tshuaj loog hauv zos;
- nrog bronchospasm uas tshwm sim thaum lub sij hawm tshuaj loog;
- rau hypotension refractory rau hloov kua;
- rau kev kho mob hypoglycemia tshwm sim los ntawm kev noj ntau dhau ntawm insulin;
- kom txhob los ntshav;
- nrog qhib-lub kaum ntse ntse txhawm rau nthuav cov menyuam kawm ntawv;
- nyob rau hauv kev kho mob ntawm priapism.
YContraindications
Epinephrine hydrochloride tsis pom zoo los ntawm cov kws tshaj lij rau:
- hypersensitivity, ntshav siab;
- xeeb tub;
- hypertrophic cardiomyopathy;
- IHD thiab tachyarrhythmias;
- cov neeg muaj ventricular fibrillation;
- pheochromocytoma;
- pub mis niam.
Kev saib xyuas yuav tsum tau ua thaum cov neeg mob muaj cov kab mob hauv qab no thiab cov mob:
- hypercapnia;
- ventricular arrhythmia, atrial fibrillation thiab hypoxia;
- pulmonary hypertension;
- mob ntshav siab,traumatic los yog cardiogenic poob siab;
- Ythyrotoxicosis;
- kab mob occlusive vascular;
- Raynaud's disease;
- atherosclerosis lossis Buerger's disease;
- mob ntshav qab zib endarteritis;
- cerebral atherosclerosis;
- Parkinson's disease;
- mob ntshav qab zib mellitus thiab lub kaum ntse kaw glaucoma;
- nce qaug dab peg;
- prostate hypertrophy;
- cov neeg muaj metabolic acidosis;
- tom qab mob khaub thuas;
- tom qab myocardial infarction;
- Cov menyuam yaus thiab cov neeg laus.
Epinephrine: cov lus qhia rau kev siv
tshuaj raws li Epinephrine feem ntau yog siv tshuaj intramuscularly lossis subcutaneously. Tsis tas li ntawd, cov tshuaj tau muab tso rau hauv cov hlab ntsha.
Rau qhov kev pab ntawm kev mob hawb pob, tshuaj bronchial yog muab tshuaj subcutaneously ntawm 0.3-0.5 mg.
Txhawm rau ncua lub sijhawm ntawm cov tshuaj loog hauv zos, cov tshuaj tau muab tshuaj ntawm 5 mcg / ml.
Epinephrine yog siv tshuaj pleev kom tsis txhob los ntshav. Ib tug swab soaked nyob rau hauv ib tug tov yog siv rau qhov chaw puas.
Kev txhaj tshuaj Intracardiac yog qhia rau asystole, thiab txhaj tshuaj hauv cov hlab ntsha thaum lub sijhawm resuscitation.
Kev kho rau qhov qhib-lub qhov muag glaucoma yog ua los ntawm instilling ib 1-2% tshuaj rau hauv lub qhov muag cuam tshuam, 1 tee ob zaug ib hnub twg.
Side effects
Raws li kws kho mob, epinephrine tuaj yeem ua rau:
- angina, tachycardia, palpitations, bradycardia, qis lossis ntshav siab;
- ventricular arrhythmia,mob hauv siab, mob plawv arrhythmia;
- ntxhov siab, tshee, kiv taub hau thiab mob taub hau;
- xav nkees, txias lossis kub, ntxhov siab;
- insomnia, NS arousal, spontaneous leeg contractions, disorientation, thiab lwm yam.
Analogues
Dab tsi tuaj yeem hloov kho qhov peb tab tom xav txog? Epinephrine muaj nyob rau hauv kev npaj xws li epinephrine hydrotartrate, epinephrine, epinephrine hydrotartrate, epinephrine tartrate, epinephrine hydrochloride - Vial.
Nws yuav tsum tau sau tseg tias articaine, epinephrine yog ib feem ntawm "Septanest" nrog adrenaline, "Alfakaina SP", "Artikaina INIBSA", "Artifrin", "Primakaina" nrog adrenaline, "Ultracaina D-S", "Ubistezin, Brilocaine-adrenaline, Articaine DF, Cytopicture, Articaine Perrel nrog adrenaline.
Reviews
Muaj ob peb qhov kev tshuaj xyuas ntawm cov khoom hauv nqe lus nug. Qhov no yog vim qhov tseeb tias cov tshuaj no tsuas yog siv thaum muaj xwm txheej ceev thiab hauv tsev kho mob.
Raws li cov kws tshaj lij, epinephrine yog ib yam khoom tseem ceeb uas feem ntau pab cawm tus neeg mob txoj sia.
