Parathyroid hormone nce siab: ua rau, cov tsos mob thiab kev kho mob

Cov txheej txheem:

Parathyroid hormone nce siab: ua rau, cov tsos mob thiab kev kho mob
Parathyroid hormone nce siab: ua rau, cov tsos mob thiab kev kho mob

Video: Parathyroid hormone nce siab: ua rau, cov tsos mob thiab kev kho mob

Video: Parathyroid hormone nce siab: ua rau, cov tsos mob thiab kev kho mob
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Hormons muaj txiaj ntsig zoo rau kev ua haujlwm ntawm tib neeg lub cev thiab lub cev. Lawv lub luag haujlwm hauv lub cev tseem tsis tau nkag siab tag nrho. Ntau tus neeg hnov txog qhov muaj qee yam tshuaj hormones thawj zaug ntawm tus kws kho mob lub sijhawm. Txawm hais tias nws yog qhov ua tsis tiav hauv cov kab ke endocrine uas tuaj yeem ua rau muaj kev loj hlob ntawm cov kab mob loj. Parathyroid hormone muaj txiaj ntsig zoo rau lub cev. Dab tsi yog nws, cov qauv ntawm cov tshuaj hormones no nrog kev ua haujlwm zoo ntawm txhua lub cev thiab lub cev ntawm lub cev, peb yuav xav txog hauv kab lus.

YDab tsi yog parathyroid hormone

Parathyroid hormone (PTH) yog ib yam tshuaj uas tsim los ntawm cov qog parathyroid, nyob rau hauv cov thyroid caj pas nws tus kheej los yog ntawm nws phab ntsa. Feem ntau muaj plaub lub qog parathyroid hauv tib neeg lub cev, tab sis qee zaum pom ntau dua.

Kev piav qhia ntawm parathyroid hormone
Kev piav qhia ntawm parathyroid hormone

Lub luag haujlwm tseem ceeb ntawm cov tshuaj parathyroid yog tswj kom tsis pub dhau ib txwm txwv cov calcium thiab phosphorus hauv lub cev. Yog tias tsis muaj calcium, qhov tso zis ntau ntxiv ntawm PTH pib, thiab rov ua dua. Qhov no tso cai rau koj los tswj cov qib ntawm cov kab hauv qab ntawm qib kom raug. NtawmRaws li kev cuam tshuam ntawm cov tshuaj hormones parathyroid, yog tias tsim nyog, calcium raug muab los ntawm lub cev pob txha, vim nws nyob ntawd qhov tseem ceeb ntawm nws nyob. Ntau dhau leaching ntawm cov kab mob tshwm sim los ntawm kev nce hauv PTH hauv cov ntshav.

Lub luag haujlwm ntawm cov tshuaj no hauv lub cev yog qhov nyuaj rau overestimate. Tom qab tag nrho, calcium, uas tswj cov tshuaj hormones parathyroid, koom nrog ntau cov txheej txheem - hauv cov leeg nqaij, hauv kev ua haujlwm ntawm lub paj hlwb, hauv cov ntshav txhaws thiab ntau lwm tus.

Kev ua haujlwm thiab lub luag haujlwm ntawm parathyroid hormone (PTH)

Cov tshuaj hormone zoo sib xws, ntxiv rau kev tswj cov qib calcium, ua lwm yam haujlwm tseem ceeb hauv lub cev:

  • txhawb nqa kev tshem tawm phosphorus;
  • tiv thaiv kev tawm ntawm calcium los ntawm lub cev nrog cov zis;
  • controls vitamin D cov ntsiab lus;
  • tiv thaiv rickets, ntshav qab zib thiab thyrotoxicosis;
  • zoo cuam tshuam rau kev ua haujlwm ntawm lub raum thiab cov qog adrenal;
  • tiv thaiv kev cuam tshuam ntawm endocrine system;
  • nrog cov calcium ntau ntxiv hauv cov ntshav coj nws mus rau cov pob txha;
  • txhawb kev tsim cov hydrochloric acid hauv plab.
  • Lub luag haujlwm ntawm calcium hauv lub cev
    Lub luag haujlwm ntawm calcium hauv lub cev

Diagnostic method

Ntau zaus, kev tshuaj xyuas ntawm qib ntawm cov tshuaj parathyroid yog muab rau cov neeg mob uas muaj kab mob ntawm cov hlab ntsha musculoskeletal. Cov ntshav venous yog siv rau kev kuaj mob. Tus nqi ntawm cov tshuaj hormones hauv cov ntshav sib txawv txhua hnub. Nws ncav cuag nws qhov siab tshaj plaws thaum hmo ntuj, thiab nws qhov tsawg kawg nkaus qhov tseem ceeb nyob ib ncig ntawm 7 teev sawv ntxov.

Kom tau txais txiaj ntsig zoo tshaj plaws, kev tshuaj xyuas yog ua tiavntawm lub plab khoob Hnub ua ntej nws, tsis txhob haus luam yeeb, noj tshuaj thiab haus cawv. Koj tseem yuav tsum tso tseg kev ua ub ua no thiab sim tsis txhob ntshai.

kuaj ntshav hormonal
kuaj ntshav hormonal

ntsuas ntsuas ntsuas

Cov lus qhia rau kev kawm txog qib ntawm parathyroid hormone hauv lub cev yog cov hauv qab no:

  • osteoporosis;
  • urolithiasis;
  • nce lossis txo cov calcium hauv cov ntshav;
  • pob txha ntau zaus;
  • cov txheej txheem osteosclerotic ntawm lub cev vertebral;
  • hloov pauv hauv cov pob txha ntawm qhov xwm txheej;
  • Kev xav txog qhov muaj cov qog nyob hauv cov qog parathyroid.

Norms

Cov qauv ntawm cov tshuaj hormones tsis hloov pauv ntawm poj niam txiv neej - ob qho tib si hauv cov txiv neej thiab cov poj niam, cov ntsuas ib txwm yuav zoo ib yam. Thaum txiav txim siab txog qib ntawm cov tshuaj hormones, lub hnub nyoog ntawm tus neeg mob yuav tsum raug coj mus rau hauv tus account.

Qeb Vim, pg/ml
Yug rau 22 12, 0 - 95, 0
23 - 70 xyoo 9, 5 - 75, 0
Tom qab 71 4, 7 - 115, 0
9, 5 - 75, 0

siab parathyroid hormone

Nyob hauv ntau tus neeg mob, tom qab tau txais cov txiaj ntsig ntawm kev tshuaj ntsuam, cov lus nug tshwm sim: "Yog tias cov tshuaj parathyroid nce siab - qhov no txhais li cas?" Thaum lub cev ua haujlwm zoo, muaj kev nce ntxivPTH nyob rau hauv teb rau calcium depletion. Raws li txoj cai, tom qab kho qhov sib npaug, qib ntawm cov tshuaj hormones rov qab mus rau qhov qub. Tab sis muaj kev nce ntxiv hauv cov ntsiab lus ntawm PTH. Qhov tshwm sim ntawm qhov no yog nce ntshav thiab calcium ntau ntxiv, uas qee zaum tuaj yeem ua rau hypercalcemia.

kws kho mob txhawb nqa
kws kho mob txhawb nqa

Hyperparathyroidism feem ntau muab faib ua hom hauv qab no:

  • Pib. Kev ua txhaum cai tshwm sim vim kev ua haujlwm tsis zoo ntawm cov qog parathyroid.
  • Secondary. Tus mob no yog provoked los ntawm hypocalcemia, thaum tsis muaj calcium nyob rau hauv cov ntshav.
  • Tertiary. Hom hyperparathyroidism no tsis tshua muaj tshwm sim. Nws tshwm sim tawm tsam keeb kwm yav dhau los ntawm theem nrab, thaum cov laj thawj tau raug tshem tawm lawm, tab sis kev tsim tawm ntawm PTH txuas ntxiv hauv qhov ntim ntau ntxiv.
  • YPseudohyperparathyroidism. Nrog rau hom no, qhov nce hauv cov tshuaj hormones tsis tshwm sim vim kev ua haujlwm ntawm cov qog parathyroid, tab sis yog tsim los ntawm cov qog ntawm cov ntaub so ntswg thib peb.

Yog tias cov tshuaj parathyroid nce siab, kev kho thiab ua rau yuav cuam tshuam. Thaum muab tshuaj kho, koj yuav tsum xub nrhiav qhov chaw ntawm qhov teeb meem.

Yog vim li cas nce

Muaj ntau yam ua rau nce cov tshuaj hormones parathyroid. Thiab txhua tus ntawm lawv ua rau ib hom mob hyperparathyroidism. Piv txwv li, cov kab mob txaus ntshai hauv qab no tuaj yeem ua rau thawj hom:

  • benign thyroid qog - qhov no yog qhov ua rau kev loj hlob ntawm thawj hom kab mob;
  • raum tsis ua haujlwm;
  • blastoma;
  • adenoma;
  • carcinoma.

Yog vim li cas rau hom thib ob yog:

  • raum pathology;
  • tsis muaj calcium;
  • Ythyrotoxicosis;
  • vitamin D deficiency;
  • kab mob pob txha;
  • ntau tus mob myeloma.

Qhov ua rau muaj zog parathyroid hormone hauv cov ntshav ntawm tertiary hyperparathyroidism yog neoplasms ntawm cov thyroid caj pas uas tshwm sim los ntawm kev loj hlob ntawm cov kab mob uas tau hais los saum no. Hauv cov ntsiab lus yooj yim, nyob rau hauv muaj cov kab mob uas ua rau hom thib ob ntawm hyperparathyroidism, qib ntawm PTH yog nce. Ib qho kev nce ntxiv ua rau hom tertiary thiab tuaj yeem ua rau kev loj hlob ntawm cov qog.

Qhov ua rau pseudohyperparathyroidism yog cov qog ntawm lub cev tsis cuam tshuam nrog cov thyroid caj pas. Yog li ntawd, yog tias tsis muaj cov kab mob pathological tau pom thaum lub sijhawm kuaj mob, ces nws tsim nyog nrhiav qhov ua rau hauv lwm lub cev.

Yog tias cov tshuaj hormones parathyroid nce siab hauv tus txiv neej, qhov laj thawj ntawm qhov no yuav tsis txawv ntawm qhov tshwm sim ntawm pathological deviations los ntawm tus qauv hauv tus poj niam. Nws tsuas yog tsim nyog sau cia tias nrog lub hnub nyoog, qhov kev pheej hmoo ntawm kev nce cov tshuaj hormones hauv cov poj niam yog siab dua me ntsis.

Ntawm tus kws kho mob
Ntawm tus kws kho mob

Cov tsos mob ntawm nce cov tshuaj hormone

Yog tias cov tshuaj parathyroid nce siab, qhov ua rau thiab cov tsos mob yuav cuam tshuam thiab tuaj yeem cuam tshuam tag nrho cov kabmob thiab lub cev ntawm lub cev.

Cov tsos mob ntxov tshaj plaws yog nqhis dej heev thiab tso zis ntau zaus. Lwm cov cim qhia ntawm siab PTH yog:

  • mob pob qij txha;
  • tawg;
  • txhim kho osteoporosis;
  • skeletal deformation;
  • menyuam yaus tuaj yeemstunted;
  • hniav ruv;
  • plab hnyuv;
  • raum pob zeb tsim;
  • mob nraub qaum;
  • kab mob raum;
  • cem quav;
  • poob qab los;
  • Qee zaum poob phaus sai;
  • xav qhuav qhov ncauj;
  • ntuav thiab xeev siab;
  • lub plawv dhia tsis zoo thiab ntshav siab;
  • Kuv muaj zog, viav vias, kev tsis txaus siab;
  • muscle cramps.

Txoj kev tshwm sim ntawm kev nce siab PTH

Ntau tus xav paub dab tsi yog qhov txaus ntshai ntawm kev nce cov tshuaj hormones parathyroid? Txij li thaum PTH cuam tshuam rau kev ua haujlwm ntawm ntau lub cev thiab lub cev ntawm tib neeg, kev sib txawv ntawm cov qauv hauv nws cov txiaj ntsig tuaj yeem ua rau muaj ntau yam kab mob. Cov no suav nrog:

  • pob txha thiab pob txha mos;
  • raum pob zeb tsim;
  • calcification thiab ua rau mob plab rwj thiab circulatory disorders - qhov no yog vim qhov tseeb tias calcium ntsev kuj tuaj yeem kov cov hlab ntsha;
  • tumor formation.

Tab sis qhov teeb meem txaus ntshai tshaj plaws ntawm kev nce siab parathyroid hormone yog hyperparathyroid ntsoog. Qhov no yog lub npe ntawm tus mob uas theem ntawm calcium nyob rau hauv cov ntshav nce sharply mus rau 3.5-5 mmol / l. Ib tug neeg dheev pib hnov mob hauv plab, tsis nco qab, qhov kub thiab txias nce mus txog 40 degrees. Tej zaum yuav ntuav. Cov kab mob no tuaj yeem ua rau muaj kab mob, cev xeeb tub, siv cov khoom noj uas muaj calcium thiab siv cov tshuaj antacids.("Rennie", "Almagel").

Kev ntsuas rau qhov kev kub ntxhov no yuav nyob ntawm seb nws tau kuaj thiab kho li cas thaum ntxov. Tab sis tseem, qhov kev pheej hmoo ntawm kev tuag los ntawm nws yog kwv yees li 50%.

nce parathyroid hormone
nce parathyroid hormone

qis parathyroid hormone

Kev txo qis hauv qib ntawm parathyroid hormone tsawg dua li qhov nce. Cov laj thawj rau tus mob no yuav yog:

  • kev txhim kho ntawm cov qog parathyroid;
  • thyroid raug mob;
  • kev txo qis cov tshuaj hormones tom qab;
  • mob autoimmune;
  • kho mob ntawm hyperparathyroidism;
  • tumors;
  • Yhypothyroidism.

Cov tsos mob ntawm qis parathyroid hormone yog:

  • pom qhov tsis pom kev;
  • mob cramps;
  • kev puas hlwb;
  • kev ua txhaum ntawm kev ua haujlwm ntawm tus kheej;
  • tawm hws ntau dhau;
  • kiv taub hau;
  • lub plawv dhia tsis zoo;
  • deterioration ntawm cov hniav enamel, zoo ntawm cov plaub hau thiab rau tes.

Cov tsos mob no tuaj yeem ua rau tib neeg lub neej zoo, tab sis nrog kev kho raws sij hawm, cov tshuaj hormones rov qab los. Yog tias kev kho mob tsis tau sau tseg ntev, yuav muaj teeb meem loj.

Kev kho mob

Paub txog cov laj thawj ntawm qhov nce hauv parathyroid hormone, kev kho mob yuav raug sau ua ntej kom tshem tawm lawv. Raws li txoj cai, kev phais yog qhia rau kev kho mob ntawm thawj hyperparathyroidism hauv feem ntau. Qhov no tshem tawm cov qog los yog ib feem ntawm cov thyroid caj pas. Tom qab kev ua haujlwm tuaj yeemyuav tsum noj tshuaj hormonal.

Thaum muaj qhov nce me ntsis, tus kws kho mob tuaj yeem txiav txim siab sau cov khoom noj uas tsim nyog, txwv tsis pub noj ntsev, nqaij tais, thiab cov khoom noj pickled thiab haus luam yeeb.

Txhawm rau kho tus mob hyperparathyroidism theem nrab, ua ntej ntawm tag nrho cov, nws yog ib qho tsim nyog los tshem tawm cov kab mob hauv qab uas ua rau ua txhaum ntawm PTH qib. Ua, piv txwv li, kho cov kab mob plab lossis raum. Yog hais tias nyob rau tib lub sij hawm ib tug txo cov calcium nyob rau hauv cov ntshav tau kuaj, ces cov kev npaj uas muaj cov kab mob no yog muab. Vitamin D kuj tseem qhia tau.

Nyob rau hauv lub xeev ntawm hyperparathyroid ntsoog, kev kho mob yuav tshwm sim nyob rau hauv lub intensive kev saib xyuas, qhov twg theem ntawm calcium nyob rau hauv cov ntshav yog tswj los ntawm nws cov binding. Dialysis therapy thiab parathyroid hormone antagonists kuj tseem siv. Kev kho mob tseem ceeb rau kev kub ntxhov yog kev siv calcitonite, ib yam tshuaj uas pab calcium txav ntawm cov ntshav mus rau cov pob txha.

Yog tias koj paub qhov ua rau thiab cov tsos mob ntawm kev nce hauv cov tshuaj hormones parathyroid, kev kho yuav zoo tshaj plaws.

Kho kho cov tshuaj hormones parathyroid qis, teriparatide (kho tshuaj PTH), cov tshuaj calcium thiab vitamin D. Cov tshuaj sedative thiab anticonvulsant kuj raug sau. Los ntawm pej xeem cov tshuaj, nyob rau hauv tsis muaj contraindications, koj muaj peev xwm siv ib tug decoction ntawm birch buds thiab blackcurrant nplooj.

kuaj ntshav
kuaj ntshav

Kev Tiv Thaiv

Raws li kev tiv thaiv kab mob thyroid, nws yog ib qho tsim nyog yuav tsum ua tib zoo saib xyuas nws txoj kev noj qab haus huv, ua ntu zus mus kuaj rauqib ntawm cov tshuaj hormones nws synthesizes. Kev kho mob ntawm tus kab mob thiab kis kab mob yog tsim nyog. Yog tias muaj kev ua haujlwm ntawm cov qog, kev saib xyuas zoo yog tsim nyog rau lawv. Nws raug pom zoo kom noj cov zaub mov uas muaj calcium thiab tsis suav nrog cov phosphorus - tsev cheese, cws, ntses hiav txwv thiab lwm yam.

Nws yog ib qho tseem ceeb heev uas yuav tau saib xyuas koj tus mob thiab, thaum thawj cov tsos mob, mus ntsib kws kho mob sai li sai tau kom dhau qhov kev ntsuam xyuas tsim nyog.

Zoo kawg

Kev cuam tshuam ntawm qib ntawm parathyroid hormone hauv cov ntshav, tshwj xeeb tshaj yog nws nce, tuaj yeem ua rau muaj ntau yam kab mob txaus ntshai. Thaum thawj cov tsos mob, nws yog ib qho tseem ceeb mus ntsib tus kws kho mob raws sij hawm, leej twg yuav txiav txim siab txog qhov tsim nyog kho. Kev kho tus kheej yog nruj me ntsis txwv tsis pub: tus kws kho mob endocrinologist yuav tsum saib xyuas lub xeev ntawm kev noj qab haus huv thiab cov txheej txheem ntawm tus kab mob, tswj hwm cov qib ntawm cov tshuaj hormones thiab microelements hauv cov ntshav. Kev sim kho tus kheej tuaj yeem ua rau muaj kev phom sij rau koj txoj kev noj qab haus huv.

Nws yog ib qho tseem ceeb heev uas yuav tsum nco ntsoov tias kev kuaj mob raws sij hawm tsis tuaj yeem tiv thaiv kev loj hlob ntawm cov teeb meem loj, tab sis qee zaum, cawm txoj sia.

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