Amoxicillin trihydrate yog cov tshuaj tua kab mob ntawm cov pab pawg ntawm semi-synthetic penicillins. Nws muaj qhov dav spectrum ntawm kev ua. Feem ntau, cov kws kho mob sau cov tshuaj no rau lawv cov neeg mob rau ntau yam kab mob sib kis. Hauv kab lus no, koj yuav kawm cov ntaub ntawv los ntawm cov lus qhia rau kev siv amoxicillin trihydrate.
Cov khoom xyaw thiab cov khoom xyaw nquag
Cov tshuaj yog muag hauv daim ntawv gelatin capsules nrog lub hau liab. Hauv cov tshuaj ntsiav yog lub teeb grey granular hmoov.
Cov tshuaj ntawm ib ntsiav tshuaj: amoxicillin trihydrate - 573.9 mg, gelatin - txog 96 mg; capsule cap: titanium dioxide (E171) - 0.5 mg, dye "hnub poob" daj (E110) - 0.13774 mg, azorubine (E122) - 0.1 mg; Lub cev lub cev: titanium dioxide (E171) - 0.6 mg. Qee lub tuam txhab tshuaj kuj tseem ntxiv lactose rau cov mis.
Tus nqi ntawm amoxicillin trihydrate nyob ntawm seb muaj pes tsawg leegtshuaj thiab cim-ups ntawm lub khw muag tshuaj saw. Qhov nruab nrab, ib pob ntawm cov ntsiav tshuaj yuav raug nqi tus neeg yuav khoom ntawm 100 thiab 300 rubles.
Cov lus qhia luv luv txog cov khoom xyaw nquag
Cov tshuaj ua ntej ntawm amoxicillin trihydrate yog ampicillin. Amoxicillin muaj cov kua qaub ntau dua, nws yuav luag tag nrho los ntawm kev tswj qhov ncauj. Alas, zoo li cov neeg ua ntej ampicillin, amoxicillin yog hepatotoxic heev. Lub bioavailability Performance index tsis cuam tshuam txog kev noj zaub mov, uas txhais tau hais tias tus neeg mob tuaj yeem noj cov tshuaj amoxicillin trihydrate txhua lub sijhawm yooj yim rau nws, thiab qhov no yuav tsis cuam tshuam rau kev nqus ntawm ib qho twg.
Nyob li ntawm 2 teev, cov tshuaj tau nqus tag nrho hauv cov hnyuv. Tom qab 3 teev tom qab noj cov tshuaj, cov tshuaj nquag nquag tuaj yeem pom hauv cov ntshav. Nyob rau hauv lub plab hnyuv siab raum, qhov concentration yog tsawg, vim hais tias ntawm no, cov tshuaj tsis raug muab rau kev kho mob ntawm plab hnyuv kab mob.
Cov tshuaj nquag yuav luag tag nrho los ntawm kev ua ntawm cov kab mob beta-lactamase enzymes. Yog li ntawd, nws tsis tsim nyog los sau nws rau kev kho mob ntawm cov kab mob provoked los ntawm beta-lactamase-producing hom.
Pharmacological action
Amoxicillin trihydrate yog ib qho tshuaj tua kab mob ntawm ib pawg kws tshuaj ntau ntawm cov tshuaj penicillins semi-synthetic. Nws muaj qhov dav spectrum ntawm kev ua. Raws li nws cov mis molecular, nws yog ib feem analogue ntawm ampicillin. Txoj kev kho no yog tus yam ntxwv me me, tab sis tsis tsawgCov kab mob bactericidal zoo.
Qhia tawm kev ua haujlwm tawm tsam aerobic Gram-positive thiab aerobic Gram-negative bacteria.
Cov kab mob thiab cov tshuaj uas tsim cov tshuaj penicillinase tau pom tias muaj kev tiv thaiv rau cov tshuaj hauv kev tshawb fawb hauv chav kuaj.
Thaum cov tshuaj tua kab mob amoxicillin thiab ampicillin cuam tshuam, nws yog tus yam ntxwv uas cov kab mob yuav muaj kev tiv thaiv tiv thaiv lawv.
Cov lus qhia rau kev siv
Cov tshuaj nquag ua tiav dhau los ntawm histohematic barrier. Muab cov tshuaj kho mob kom sai thiab zoo.
Cov tshuaj no zoo tshaj plaws rau cov kab mob ntawm cov kab mob sib kis ntawm lub cev hauv qab no:
- urinary system;
- plab hnyuv (tsis suav nrog cov hnyuv hauv qab);
- teeb meem ntawm daim tawv nqaij, kab mob dermatitis, furunculosis;
- kab mob ntsws sab sauv.
Feem ntau tau sau rau hauv kev kho mob ntawm ntau hom kab mob gonorrhea, salmonella, kab mob Lyme. Nrog cov kab mob no, nws tsis tuaj yeem lees txais kev kho tus kheej. Tus nqi npaum li cas ntawm cov tshuaj tsuas yog muab los ntawm tus kws kho mob tom qab tau txais cov txiaj ntsig kev xeem.
Hauv kev kis mob hnyav, nws zoo dua yog siv amoxicillin trihydrate thiab clavulanic acid tib lub sijhawm. Nws tuaj yeem siv ob qho tib si hauv ntsiav tshuaj thiab daim ntawv txhaj tshuaj.
Amoxicillin trihydrate rau tsiaj
Cov tshuaj yog siv los khotsiaj txhu thiab miv, dev. Tau 40 xyoo nws tau nquag siv tshuaj kho tsiaj rau kev kho mob ntawm:
- kab mob ntawm plab hnyuv kab mob ntawm cov kab mob - gastroenteritis, gastroenterocolitis;
- kab mob ua pa - bronchitis, mob ntsws hauv tsiaj;
- tom qab phais rau abscesses, ntau yam o;
- kis kab mob ntawm cov zis hauv cov tsiaj (endometritis, urethritis, pyelonephritis);
- hauv kev kho mob mastitis, leptospirosis, actinomycosis, parainfluenza thiab paratyphoid hauv npua thiab nyuj.
Cov lus qhia rau kev siv amoxicillin trihydrate rau cov tsiaj pom zoo kom siv cov tshuaj txhaj tshuaj, vim tias daim ntawv ntsiav tshuaj tsis zoo los ntawm ntau tus neeg sawv cev ntawm tsiaj ntiaj teb.
Recommended dosages
Cov koob tshuaj pib rau cov neeg laus yuav tsum tsis pub tshaj 1500 mg (uas yog peb 500 mg ntsiav tshuaj) ib hnub. Nruab nrab ntawm cov koob tshuaj ntawm txhua lub ntsiav tshuaj lossis ntsiav tshuaj yuav tsum tsis pub tsawg dua 3 teev.
Raws li kev txiav txim siab ntawm tus kws kho mob uas tuaj koom yog tias muaj kab mob hnyav, koob tshuaj txhua hnub yuav nce mus rau 2 g ntawm cov tshuaj.
Nyob rau hauv cov mob gonorrhea, ob koob tshuaj, 2 lossis 3 g ib zaug, raug pom zoo. Ib hnub tom qab, nws yog ib qho tsim nyog yuav tsum rov xeem dua kom paub tseeb tias qhov kev kho mob zoo.
Yog tias muaj kab mob sib kis thiab kab mob ntawm txoj hnyuv, nws raug nquahu kom noj 1 mus rau 2 g ib hnub. Lub sijhawm ntawm kev kho yog nyob ntawm qhov hnyav ntawm cov tsos mob thiab tus mobtus neeg mob noj qab haus huv.
Salmonella carriage - los ntawm 1.5 mus rau 2 g. Kev sim yog tas li yuav tsum tau saib xyuas cov txiaj ntsig ntawm kev kho.
Kev Sib Tham Tshuaj
Amoxicillin tuaj yeem txhawb kev ua haujlwm ntawm indirect anticoagulants. Ua ke nrog qhov no, nws inhibits plab hnyuv microflora thiab txo cov prothrombin index.
Kev tswj hwm ib txhij ntawm amoxicillin nrog cov tshuaj tua kab mob bactericidal ua rau muaj kev sib koom ua ke; incompatible nrog bacteriostatic tshuaj tua kab mob.
Cov poj niam noj cov tshuaj tiv thaiv qhov ncauj ntawm qhov ncauj yuav tsum nco ntsoov tias thaum noj nrog amoxicillin, txoj kev xeeb tub nce 8%.
Thaum noj tshuaj nrog cawv tinctures, feem ntau muaj kev nce hauv cov nyhuv sedative. Cov xwm txheej ntawm kev loj hlob ntawm coma tau raug kaw nrog kev noj tshuaj ntau dhau ntawm amoxicillin thaum noj cawv tshuaj tinctures.
YContraindications
Koj yuav tsum tsis txhob noj tshuaj thaum muaj cov kab mob hauv qab no:
- lymphocytic leukemia;
- kis kab mob mononucleosis;
- ua xua diathesis;
- kab mob ua pa;
- hypersensitivity rau penicillins;
- bronchial hawb pob.
Nyob rau hauv rooj plaub ntawm daim siab tsis ua hauj lwm, cirrhosis thiab lwm yam kab mob siab, nws yog txwv tsis pub noj nws nrog clavulanic acid. Noj amoxicillin trihydrate ib leeg rau cov teeb meem siabua tau tsuas yog tom qab kws kho mob cov tshuaj.
Siv los ntawm cov poj niam cev xeeb tub
Cov tshuaj tua kab mob no hla cov placental barrier. Tom qab ob peb hnub ntawm kev nkag, nws twb accumulates nyob rau hauv cov ntaub so ntswg ntawm lub embryo. Vim qhov tshwm sim ntawm qhov tshwm sim ntawm tus me nyuam hauv plab, amoxicillin trihydrate tau muab rau cov poj niam cev xeeb tub nkaus xwb hauv cov xwm txheej hnyav. Qhov kev xav tau ntawm kev kho mob rau leej niam yuav tsum tshaj qhov pom tias muaj kev pheej hmoo rau tus menyuam hauv plab.
Hnub no, muaj ntau yam tshuaj tua kab mob niaj hnub thiab nyab xeeb dua rau cov poj niam hauv qhov xwm txheej dua li cov tshuaj no. Tsis muaj cov ntaub ntawv hais txog kev hloov pauv thiab embiotoxic cuam tshuam rau tus menyuam hauv plab - tsis muaj leej twg tau ua cov kev tshawb fawb no.
Hais txog qhov no, amoxicillin trihydrate thaum cev xeeb tub hauv qhov tsis tshua muaj neeg tseem tuaj yeem muab tshuaj rau tus neeg mob, tab sis cov tshuaj raug cais raws li kev cuam tshuam rau tus menyuam hauv plab raws li FDA - B. Qhov no txhais tau tias tsis muaj kev tshawb fawb ntseeg tau. ntawm qhov tsis muaj qhov cuam tshuam rau tib neeg cov khoom ua tiav.
Kev kho cov menyuam yaus thiab cov hluas nrog amoxicillin
Kev kho mob tau txais rau cov menyuam yaus hnub nyoog 3 xyoos. Kev ncua kev hloov pauv nrog lub suab qab zib (Amoxisar) yuav tsum nyiam.
Ceev faj yuav tsum siv thaum kho cov menyuam yaus ua xua. Nws yog ib qho tsim nyog yuav tsum ua tib zoo kawm cov npe ntawm contraindications txhawm rau tiv thaiv kev tsis zoo ntawm tus mob. Cia peb muab nws ua ke nrog cov tshuaj uas muajclavulanic acid.
Cov koob tshuaj amoxicillin trihydrate rau tus menyuam yuav tsum tau kuaj nrog tus kws kho menyuam yaus.
Cov lus qhia tshwj xeeb
Pib koob tshuaj tsawg yog tias cov neeg mob muaj lub siab xav ua xua. Tej zaum txoj kev loj hlob ntawm Quincke's edema, urticaria, khaus, xeev siab. Yog tias muaj kev tsis haum tshuaj tau sau tseg yav dhau los (tsis yog siv tshuaj), koj yuav tsum pib noj kom zoo li sai tau.
Amoxicillin ua ke nrog metronidazole yuav tsum tsis txhob siv rau cov neeg mob hnub nyoog qis dua 18 xyoo.
Thaum muaj kab mob siab ntev, kab mob siab thiab kab mob siab cirrhotic, nws tsis pom zoo kom noj amoxicillin trihydrate. Qhov no tsuas yog ua tau thaum muaj xwm txheej hnyav thaum tus neeg mob lub neej raug hem thiab tsis muaj cov tshuaj tua kab mob uas muaj cov tshuaj lom hauv lub siab thiab lub gallbladder.
Ntawm keeb kwm ntawm kev sib xyaw ua ke, nws tsis pom zoo kom siv ethanol. Qhov no ua rau kom muaj kuab lom hauv lub siab thiab ua rau muaj kev pheej hmoo ntawm kev tsis haum tshuaj.
Analogues ntawm cov tshuaj
Ntawm no yog cov tshuaj nrov tshaj plaws uas amoxicillin trihydrate yog cov khoom xyaw tseem ceeb:
- "Amoxisar";
- "Grunamox";
- "Gonoform";
- "Amosin";
- "Ecoball".
Qee ntawm lawv muaj nyob rau hauv cov ntsiav tshuaj thiab tshuaj ntsiav rau kev tswj qhov ncauj, ib txhia - nyob rau hauv daim ntawv ntawm suspensions los yog ampoules rau txhaj. Lub hauv paus ntsiab lus ntawm kev siv thiab koob tshuaj nyob rau hauv txhua rooj plaub yuav txawv.
Analogues ntawm amoxicillin trihydrate tsis phem dua li thawj cov tshuaj. Tus nqi sib txawv me me. Yog li tsis muaj kev nkag siab qhov kev nyiam rau ib tus ntawm lawv.
Tus kws kho mob lub tswv yim txog cov tshuaj no
Ntau tus kws kho mob hais tsis zoo txog cov tshuaj raws li amoxicillin trihydrate, xav tias lawv tsis siv lawm. Lawv ua pov thawj qhov kev pom no los ntawm qhov tseeb tias ntau cov kab mob tau ntev los tiv thaiv nws cov teebmeem. Yog li, noj tshuaj ntau ntau ntawm cov tshuaj lom rau lub siab tsuas yog ua rau lub cev tsis zoo.
Tab sis feem ntau cov kws kho mob thiab cov kws kho mob txuas ntxiv mus tshuaj amoxicillin trihydrate raws li cov khoom lag luam rau lawv cov neeg mob. Feem ntau, clavulanic acid tau muab tshuaj ua ke txhawm rau txhawm rau "tiav" cov haujlwm ntawm cov kab mob uas tau tawm tsam ib qho amoxicillin.
