Dicynone ntsiav tshuaj yog cov tshuaj hemostatic siv los nres los ntshav ntawm ntau yam, nrog rau hemorrhages thiab kab mob ntawm lub retina, muaj zog poj niam cev xeeb tub. Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tshuaj rau drip infusions thiab intramuscular txhaj, ua nyob rau hauv Slovenia.
Cia peb saib ze dua ntawm cov ntsiav tshuaj Dicinon. Los ntawm qhov lawv nthuav rau ntau.
Form and composition
Cov tshuaj yog tsim nyob rau hauv ob hom: txhaj tshuaj thiab ntsiav tshuaj. Cov tom kawg yog pleev xim rau yuav luag dawb lossis dawb, lawv qhov ntau npaum li cas yog 0.05 lossis 0.25 grams, lawv nyob hauv ib pob ntawm tes. Lub thawv ntim muaj ib puas Dicinone ntsiav tshuaj ntawm 250 mg lossis 50 mg (cov menyuam yaus noj) ntawm cov khoom tseem ceeb ntawm etamsylate, nrog rau cov khoom ntxiv, suav nrog magnesium stearate, lactose, anhydrous citric acid, povidone K25, pob kws starch.
Pharmacological action
Dicynone ntsiav tshuajyog hemostatic. Cov nyhuv hemostatic yog raws li qhov nrawm ntawm thawj theem ntawm hemostasis - muaj kev txhawb nqa ntawm kev sib cuam tshuam ntawm platelets thiab endothelium. Dicinon tsub kom platelet adhesion rau cuam tshuam vascular phab ntsa, tshwj xeeb tshaj yog rau capillaries, tiv thaiv endothelium, txo permeability ntawm capillary phab ntsa, inhibits prostaglandin biosynthesis, uas ua rau vasodilation thiab disaggregation, thiab yog li ntawd nce capillary permeability. Vim muaj kev cuam tshuam ntawm cov tshuaj, los ntshav tau txo qis, ntshav poob qis.
Cov tshuaj tsis muaj vasoconstrictive. Nws tsis cuam tshuam rau cov txheej txheem ntshav coagulation lossis fibrinolysis, yog li nws tsis muaj cov nyhuv thrombogenic. Cov tshuaj inhibits cov teebmeem ntawm ob qho tib si histamine thiab hyaluronidase, yog li txo qis capillary permeability ntawm ntau yam kab mob, piv txwv li, hauv cov txheej txheem inflammatory. "Dicynone" txo qhov zaus ntawm los ntshav nyob rau hauv lub ventricles ntawm lub paj hlwb nyob rau hauv cov me nyuam mos uas tsis muaj qhov ceeb thawj. Cov me nyuam mos uas leej niam tau txais cov tshuaj no muaj lub paj hlwb qis dua cov niam uas tsis tau txais cov tshuaj.
Cov ntsiav tshuaj Dicynon ua haujlwm sai npaum li cas los ntshav?
YPharmacokinetics
Thaum tswj qhov ncauj, cov tshuaj nquag tau nqus ntawm tus nqi siab los ntawm txoj hnyuv. Thaum 50 milligrams ntawm etamsylate tau noj qhov ncauj, nws qhov siab tshaj plaws plasma tau mus txog.hauv plaub teev. Nws ib nrab-lub neej los ntawm plasma yog 3.7 teev. Kwv yees li 72% ntawm cov koob tshuaj noj thaum nruab hnub yog tawm hauv cov zis.
Cov tshuaj nquag tuaj yeem nkag mus rau cov kua mis thiab cov placenta barrier.
Yog li, cov ntsiav tshuaj Dicinon - lawv yog dab tsi?
Cov lus qhia rau kev siv
"Dicynone" hauv cov ntsiav tshuaj yog sau rau hauv cov xwm txheej hauv qab no:
- Tiv thaiv kom tsis txhob los ntshav.
- Nrog parenchymal capillary los ntshav (kev raug mob, tom qab phais, plab hnyuv, pulmonary, raum, tom qab kev kho hniav).
- Yog tias los ntshav ntawm qhov xwm txheej thib ob tawm tsam keeb kwm ntawm hypocoagulation, hematuria, thrombocytopenia, thrombocytopathy nrog hemorrhages hauv pob txha taub hau, kev siv tshuaj los ntshav, hemorrhagic vasculitis, hemorrhagic diathesis.
- Recurrent retinal hemorrhage, Werlhof's disease, ntshav qab zib retinopathy.
- Dicynone ntsiav tshuaj feem ntau yog tshuaj rau kev coj khaub ncaws.
YContraindications
Ntawm cov contraindications yog:
- rhiab heev rau cov khoom xyaw nquag ntawm cov tshuaj - etamsylate, lossis ib qho excipient;
- siab rhiab heev rau sodium sulfite keeb kwm;
- menyuam yaus hemoblastosis (osteosarcoma, myeloid thiab lymphatic leukemia);
- mob porphyria;
- thromboembolism thiab thrombosis;
- pub mis niam.
Kev cev xeeb tub thiab pub niam mispub
Kev nthuav tawm ntawm etamsylate rau cov poj niam thaum cev xeeb tub. Etamsylat hla lub placental barrier, yog li nws siv yog contraindicated nyob rau hauv cov neeg mob nyob rau hauv thawj peb lub hlis twg. Kev siv tshuaj kho mob thaum cev xeeb tub tsis cuam tshuam rau qhov kev qhia no.
Cov tshuaj nquag nkag mus rau hauv cov kua mis. Thaum noj tshuaj, koj yuav tsum tsis txhob pub mis rau koj tus menyuam.
Xav txog cov lus qhia siv rau Dicynon ntsiav tshuaj los ntshav.
Txoj kev ntawm daim ntawv thov thiab ntau npaum li cas
Siv rau cov menyuam yaus tshaj 14 xyoos thiab cov neeg laus:
- Pre-surgery: 1-2 ntsiav tshuaj ntawm 250 mus rau 500 milligrams hauv ib teev ua ntej kev phais.
- Tom qab kev phais: txhua 4-6 teev kom txog thaum muaj qhov tshwm sim los ntshav - 1-2 ntsiav tshuaj ntawm cov tshuaj ntawm koob tshuaj 250. Cov lus qhia rau kev siv rau cov ntsiav tshuaj Dicinon qhia tau tias ntau npaum li cas ntawm 500 mg tuaj yeem ua tau. siv.
- Kab Mob Hauv Tsev: Cov lus qhia dav dav yog noj ob ntsiav tshuaj peb zaug hauv ib hnub nrog zaub mov nrog dej me ntsis.
- Nrog metro- thiab menorrhagia, hauv gynecology: haus 2 ntsiav tshuaj ntawm cov tshuaj peb zaug ib hnub twg nrog zaub mov nrog dej me ntsis; Kev kho mob txuas ntxiv mus rau kaum hnub, tsib hnub ua ntej qhov xav tau los ntshav.
Kev kho cov menyuam yaus hnub nyoog tshaj rau xyoo:
- koob tshuaj thaum nruab hnub yog 10-15 milligrams ib kilogram ntawm lub cev hnyav, muab faib ua peb mus rau plaub koob. Lub sijhawm ntawm kev siv tshuaj yog txiav txim siab los ntawm qhov ntim ntawm cov ntshav poob thiab nyob ntawm peb hnubtxog li ob lub lis piam txij thaum lub sij hawm los ntshav nres nyob rau hauv ib tug neeg mob.
- Noj cov tshuaj thaum noj lossis tom qab noj mov. Cov neeg mob tshwj xeeb.
Tsis muaj kev tshawb fawb txog kev kho mob ntawm cov neeg mob lub raum tsis zoo lossis lub siab ua haujlwm siab. Yog li, Dicinon yuav tsum tau siv nrog ceev faj hauv kev kho mob ntawm pawg neeg mob no.
Yog tsis tau koob tshuaj, tsis txhob noj ob koob tshuaj kom tsis txhob noj tshuaj.
Side effects
Cov teebmeem hauv qab no tsis xav tau los ntawm cov ntsiav tshuaj Dicinon tuaj yeem tshwm sim: kiv taub hau, mob taub hau, mob ntawm daim tawv nqaij tsis zoo, hyperemia, mob epigastric, xeev siab, paresthesia ntawm qis extremities. Cov tshuaj tiv thaiv no yog ib ntus thiab tsis txaus ntshai. Muaj pov thawj hais tias nyob rau hauv cov me nyuam uas mob myelo- thiab lymphocytic leukemia, osteosarcoma, ib tug active tshuaj uas ua rau kom tsis txhob ntshav poob ua rau mob loj leukopenia. Raws li ntau qhov chaw, kev siv tshuaj rau kev kho menyuam yaus tsis pom zoo.
Muaj pov thawj tias cov poj niam uas noj Dicinon ua ntej kev cuam tshuam ntawm tus kws phais mob tau sau tseg thrombosis ntawm lub ncauj tsev menyuam tom qab phais. Tab sis kev sim tsis ntev los no tsis tau lees paub cov ntaub ntawv no.
Daim ntawv thov tshwj xeeb
Dicynone ntsiav tshuaj rau lub tsev menyuam los ntshav yuav tsum tau sau nrog ceev faj yog tias cov neeg mob muaj keeb kwm ntawm thromboembolism lossis thrombosis, ntau dhau rau cov tshuaj. Dicinone muaj sulfites, thiab yog li koj yuav tsum tau ceev faj thaumnws cov kev tswj hwm rau cov neeg mob ua xua lossis bronchial hawb pob. Ua ntej pib kho, nws yuav tsum nco ntsoov tias cov tshuaj tsis zoo hauv kev kho cov neeg mob thrombocytopenia.
Vim qhov tseeb tias cov neeg mob me uas tau muab tshuaj Dicinon los tiv thaiv kev poob ntshav hauv myeloid thiab lymphoblastic leukemia, osteosarcoma, zuj zus, ntau tus kws tshaj lij ntseeg hais tias cov tshuaj yog contraindicated nyob rau hauv cov xwm txheej zoo li no.
Cov tshuaj no yuav tsum tsis txhob muab rau cov neeg mob uas muaj kab mob tsawg xws li galactose-glucose malabsorption lossis lactase deficiency.
Cov tshuaj nquag tsis cuam tshuam rau tus neeg lub peev xwm tsav lossis siv cov tshuab ua haujlwm nyuaj.
Yog tias koj muaj kev tsis haum rau cov carbohydrates, koj yuav tsum sab laj nrog kws kho mob ua ntej noj tshuaj.
Analogues
Dicinon muaj ob peb analogues.
- "Tranexam" - cov tshuaj no yog tus neeg sawv cev hemostatic. Nws yog siv rau ntau yam los ntshav, nrog rau kev ua haujlwm tom qab, thaum cev xeeb tub, nrog cov kab mob oncological thiab daim siab pathologies. Qhov no analogue yog yus muaj los ntawm anti-inflammatory thiab anti-allergic teebmeem. Nws muaj contraindications thiab ib co kev phiv. Nws cov khoom xyaw nquag yog tranexamic acid.
- "Etamzilat" - tshuaj siv rau kev kho mob thiab tiv thaiv cov ntshav capillary, hauv gynecological thiab kho hniavkheej kheej, tom qab phais kev cuam tshuam ntawm ib qho nyuaj, nrog rau lub ntsws thiab txoj hnyuv los ntshav. Qhov no analogue muaj nws tus kheej contraindications, tom qab nws siv, kev phiv tej zaum yuav tshwm sim.
- "Vikasol" yog dej-soluble synthetic analogue ntawm vitamin K. Cov tshuaj yog siv nyob rau hauv kev phais thiab gynecological xyaum los kho thiab tiv thaiv ntau yam los ntshav. Cov analogue no tau pom zoo siv rau hauv kev kho menyuam yaus thiab thaum cev xeeb tub. Nws siv tuaj yeem ua rau muaj kev phiv, uas tshwj xeeb tshaj yog tawm tsam keeb kwm ntawm kev noj ntau dhau. Muaj contraindications. Cov tshuaj no tsis zoo hauv Werlhof tus kab mob thiab hemophilia.
Tus nqi ntawm cov ntsiav tshuaj Dicinon yuav qhia hauv qab no.
Cov lus qhia tshwj xeeb
Yog tias cov tshuaj tau muab rau cov neeg mob uas muaj keeb kwm ntawm thrombosis thiab thromboembolism, ces koj yuav tsum ceev faj. Nyob rau hauv cov ntaub ntawv ntawm overdose, hemorrhagic teeb meem tshwm sim, thaum lub sij hawm kev kho mob ntawm cov tshuaj antidotes tshwj xeeb yuav tsum tau. Thaum cev xeeb tub, Dicinon kuj tau sau nrog ceev faj.
Cov tshuaj kuj tseem siv tau rau hauv cov tshuaj kho tsiaj, piv txwv li, kho cov miv.
Kev tshuaj xyuas ntawm cov ntsiav tshuaj Dicinon
Cov tshuaj "Dicinon" yog dav siv rau kev kho mob thiab tiv thaiv los ntshav thaum muaj ntau yam kev phais mob thiab kev cuam tshuam tsawg kawg nkaus. Muaj ntau qhov kev tshuaj xyuas zoo los ntawm urologists, ophthalmologists, kws kho hniav thiab lawv cov neeg mob.
"Dicinon" yog siv nyob rau hauv gynecological teb nrog ib yam nkaus thiabhnyav kev coj khaub ncaws uas ua rau cov ntshav tsis txaus, thiab muaj teeb meem tom qab kev taw qhia ntawm cov khoom siv hauv lub cev. Yuav siv tau los kho cov poj niam cev xeeb tub.
Cov tshuaj los ntawm ntau hom, yog li nws tuaj yeem siv rau thaum muaj xwm txheej ceev txwv tsis pub cov ntshav ntws thaum muaj xwm txheej kub ntxhov lossis kub ntxhov, thiab kho cov tshuaj.
"Dicinon" tau txais txiaj ntsig zoo los ntawm cov neeg mob, tsis ua rau qhov tsis zoo ntawm kev siv. Muaj ib tug me me ntawm contraindications. Muab lub sijhawm kawm, tus nqi ntawm cov tshuaj txaus txaus.
Price of Dicynon ntsiav tshuaj
Tus nqi ntawm cov tshuaj hauv cov ntsiav tshuaj yog kwv yees li 400 rubles. Nws nyob ntawm thaj av thiab chaw muag tshuaj.
Cov Lus Qhia
Dicynone yog tshuaj hemostatic. Nws qhia cov cim qhia ntawm angioprotector.
Siv los txo cov ntshav hauv qhov tsis xws luag hauv cov hlab ntshav thiab platelet muaj nuj nqi.
Siv los txo cov ntshav poob thaum muaj kev phais. Nws txhawb kev tsim cov platelets, nce lawv cov aggregation thiab adhesion. Nws yog ib feem ntawm kev kho mob ntawm ntau yam hemorrhagic syndromes. Nws yuav tsum tau siv nrog ceev faj rau cov neeg mob uas muaj keeb kwm ntawm thromboembolism thiab thrombosis. Tus kws kho mob tau sau nruj me ntsis, nws raug sau rau cov poj niam cev xeeb tub.
