Mob myelogenous leukemia yog ib yam kab mob loj uas qee lub hlwb hauv tib neeg cov pob txha pob txha degenerate thiab ua malignant. Nyob rau tib lub sijhawm, ntau tus lej ntawm pathologically hloov pauv granulocytes yog tsim nyob rau hauv cov ntshav. Cov kab mob txaus ntshai no tuaj yeem cuam tshuam rau tib neeg ntawm txhua lub hnub nyoog. Tab sis raws li cov ntaub ntawv txheeb cais, tus kab mob no tsis tshua muaj nyob hauv cov menyuam yaus hnub nyoog qis dua 10 xyoo.
mob myeloid leukemia yog qhov nyuaj heev los kuaj pom thaum ntxov, vim tias tus kab mob no tsis muaj cov tsos mob tshwj xeeb. Qee zaum, cov neeg mob yws yws ntawm kev qaug zog, tsis qab los noj mov thiab qhov hnyav. Thaum tsaus ntuj, tawm hws tshwm, qhov kub nce. Kev hnyav thiab tsis xis nyob hauv plab tau sau tseg, raws li txoj cai, qhov no tshwm sim los ntawm kev hloov pauv pathological hauv tus po. Kuj tseem muaj qhov nce hauv cov qog ntshav qog ntshav. Yog tias koj tsis quav ntsej thawj qhov tsis meejCov tsos mob, ces, hmoov tsis, nws tsis tuaj yeem txheeb xyuas tus kab mob ntawm thawj theem.
Nov yog tus mob ntshav qab zib mob myeloid insidious. Cov laj thawj rau ncua kev kho mob kuj yog nyob rau hauv latency ntawm chav kawm ntawm tus kab mob. Tom qab cov tsos mob ntawm tus kab mob twb qhia meej meej txog cov txheej txheem pathological. Tus neeg mob tus mob deteriorates sharply. Tus naj npawb ntawm platelets thiab cov qe ntshav liab hauv cov ntshav poob. Cov tawv nqaij ua daj ntseg, cov hlab ntsha me me tau yooj yim raug mob. Muaj cov hemorrhages subcutaneous thiab dav hematomas. Kev loj hlob ntawm cov qog nqaij hlav qog nqaij hlav yog qhia ntau dua. Nodules tsim rau ntawm tus neeg mob daim tawv nqaij, lawv muaj cov leukemic granulocytes. Daim paib no tshwj xeeb tshaj yog kev txhawj xeeb thiab yuav tsum yog daim ntawv pov thawj kom pom tus kws tshaj lij.
mob myeloid leukemia feem ntau cuam tshuam rau cov pob txha, daim siab thiab tus po. Feem ntau granulocytes yog tsim nyob rau hauv cov kabmob no. Hauv ib tus neeg ib txwm muaj, cov hlwb ntawm txhua theem ntawm kev loj hlob raug kuaj pom thaum lub sijhawm tshuaj xyuas. Nyob rau hauv mob myeloid leukemia, tsuas yog cov ntaub ntawv tsis paub tab pom. Pathological (malignant) granulocytes tshem tawm cov hlwb ib txwm los ntawm cov pob txha pob txha. Qhov no feem ntau ua rau kev tsim cov ntaub so ntswg uas puas lawm uas hloov cov pob txha pob txha. Nyob rau theem ntawm kev ua kom nrawm, raws li tus kab mob loj tuaj, cov hlwb tsawg dua thiab tsis paub tab nkag mus rau hauv lub cev. Thrombocytopenia thiab anemia tshwm sim. Qee zaum mob myeloid leukemia tshwm sim vim qhov tseeb tias granulocytestau txais kev hloov pauv ntxiv, thiab tom qab ntawd qhov kev pheej hmoo ntawm kev tsim muaj kev kub ntxhov hauv tus neeg mob nce ntxiv. Nyob rau tib lub sijhawm, tsuas yog cov granulocytes tseem tsis tau paub tab yog tsim los ntawm cov qia hlwb reborn. Txoj kev ntawm tus kab mob uas muaj kev kub ntxhov tau hnyav zuj zus.
Cov kab mob myeloid mob qog noj ntshav tau kuaj pom los ntawm kev kuaj ntshav. Nws tuaj yeem kuaj pom qhov nce ntau ntawm cov leukocytes. Rau kev kuaj pom tseeb dua, kev tshawb fawb ntawm chromosomes yog siv. Txoj kev no yuav luag txhua zaus kuaj pom qhov muaj chromosomal translocations nrog qhov feem pua ntawm qhov tseeb.
