tswm ciab "Flexen" yog nyob rau hauv pab pawg kws tshuaj ntawm NSAIDs (tsis-steroidal anti-inflammatory tshuaj). Lawv muaj anti-inflammatory, antipyretic, analgesic thiab antiaggregatory teebmeem. Cov tshuaj uas nthuav tawm no thaiv kev ua haujlwm ntawm cov enzymes (cyclooxygenases 1 thiab 2) thiab cov synthesis ntawm prostaglandins. Cov txheej txheem no tiv thaiv kev tsim cov inflammatory mediators thiab inhibits zus tau tej cov leukotrienes.
Suppositories "Flexen" nthuav tawm kev ua haujlwm los tiv thaiv bradykinin, stabilize lysosomal biomembranes, ua rau inhibition ntawm neutrophil kev ua haujlwm hauv cov neeg mob kuaj mob rheumatoid mob caj dab. Tshem tawm platelet aggregation. Cov nyhuv analgesic yog vim ob qho tib si hauv nruab nrab thiab peripheral mechanisms. Ntau tus kws kho mob tau sau ntawv Flexen (tswj tswm ciab) los txo qhov mob thiab kho mob caj dab. Tus nqi ntawm cov tshuaj tso cai rau nws mus yuav los ntawm ntau pawg ntawm cov neeg mob. Kev tshuaj xyuas ntawm cov tshuaj qhia nws cov kev ua haujlwm siab thiabkev nyab xeeb kev noj qab haus huv thaum ua raws li cov lus pom zoo.
Cov lus qhia rau kev siv cov tshuaj yog qhov yooj yim heev, thiab cov kev tshuaj xyuas tau lees paub qhov pom kev kho mob. Dab tsi yog suav nrog hauv cov tshuaj? Nws muaj dab tsi? Puas muaj kev phom sij txaus ntshai? Ntau tus neeg mob tab tom nrhiav cov lus teb rau cov lus nug no.
tshuaj muaj pes tsawg leeg ntawm cov tshuaj
Cov tshuaj muaj pes tsawg leeg suav nrog cov txheej txheem bioactive thiab excipients:
- ketoprofen (lub ntsiab bioactive compound);
- beeswax;
- hydrogenated zaub roj;
- colloidal silicon dioxide;
- sodium ethyl parahydroxybenzoate;
- sorbitol;
- gelatin;
- zaub roj;
- Yglycerol;
- soy lecithin;
- titanium dioxide;
- Ysodium propyl parahydroxybenzoate.
Flexen, tswm ciab: analogues
Hauv kev xyaum kho mob, cov kws kho mob nquag siv cov tshuaj analogues saum toj no:
- YArtrosilene.
- Ketonal Duo.
- Artrum.
- Quick Gel.
- Valusal.
- Quickcaps.
- Ketonal.
- Oruvel.
- Febrofit.
- Flamax.
- Profenid.
- Ketonal uno.
Drug Benefits
Qhov zoo ntawm cov tshuaj muaj xws li cov ntsuas hauv qab no:
- siab tshaj kho cov nyhuv;
- siab bioavailabilitytshuaj piv rau nws cov phooj ywg.
Flaws of Medicine
Qhov tsis zoo ntawm Flexsen suav nrog cov hauv qab no:
- tus nqi siab ntawm cov tshuaj piv rau cov analogues;
- tawm ntawm txhua hnub (ntev) tso tawm daim ntawv.
YPharmacokinetics
Kev khi ntawm cov tshuaj bioactive ntawm cov tshuaj rau cov ntshav plasma yog 99 feem pua. Cov tswm ciab "Flexen" yog tus cwj pwm los ntawm bioavailability siab (ntau dua 90%). Kev kho mob concentration ntawm "Flexen" hauv cov ntshav yog khaws cia rau 6 teev. Lub ntsiab metabolic tawg ntawm cov tshuaj tshwm sim hauv hepatocytes los ntawm glucorination. Ib nrab-lub neej yog li ob teev. Cov tshuaj tsis sib sau ua ke, nws tsuas yog tawm los ntawm ob lub raum thiab hauv cov hnyuv.
"Flexen" (tswm ciab): cov lus qhia rau kev siv, nqe
Cov tshuaj saum toj no nthuav tawm kev kho mob dav dav ntawm kev ua haujlwm. Hauv kev kho mob, kev kho mob thiab kev mob tshwm sim ntawm ntau lub hauv paus chiv keeb, suppositories "Flexen" feem ntau tau sau tseg. Kev siv tshuaj yog pom zoo rau cov kab mob hauv qab no:
- migraine;
- psoriatic mob caj dab;
- tenosynovitis;
- gouty mob caj dab;
- bursitis;
- dorsalgia;
- myalgia;
- mob caj dab rheumatoid;
- otitis media;
- osteoarthritis ntawm ntau qhov chaw;
- polymyalgia rheumatica;
- pob txha;
- sciatica;
- phlebitis;
- ankylosing spondylitis;
- neuralgia;
- thrombophlebitis;
- sciatica;
- adnexitis;
- pathology hauv lumbosacral plexus;
- sciatica;
- algodysmenoria;
- postoperative thiab post-traumatic syndrome;
- lymphangitis;
- mob syndrome hauv oncological pathologies.
Koj tuaj yeem yuav cov tshuaj "Flexen", tus nqi ntawm qhov sib txawv ntawm 200-300 rubles, yog tias koj muaj daim ntawv xaj, koj tuaj yeem ntawm txhua lub tsev muag tshuaj. Nws kuj tseem tsim nyog sau cia tias Flexen suppositories feem ntau siv hauv gynecology, lawv tau muab tshuaj rau zes qe menyuam. Raws li cov lus tim khawv ntawm ntau tus neeg mob, cov tshuaj ua haujlwm zoo heev. Ntau tus kws kho mob hais tias tom qab kev kho mob nrog Flexen rau 10 hnub thiab tom qab noj tshuaj ntxiv, lub cyst ploj.
YContraindications
Yog tias koj txiav txim siab siv "Flexen" (tswj tswm ciab), cov lus qhia rau kev siv qhia tias cov tshuaj no yuav tsum tsis txhob siv rau hauv cov xwm txheej hauv qab no:
- los ntshav hauv plab;
- hais lus tsis ua haujlwm ntawm lub siab thiab lub raum;
- lub sijhawm lactation thiab cev xeeb tub;
- hypersensitivity rau non-steroidal tshuaj tiv thaiv kab mob;
- hemorrhoids;
- "Aspirin" hawb pob;
- ntshav txhaws ntshav;
- proctitis;
- under 15;
- ua haujlwm ntawm cov kab mob hematopoietic (leukopenia, hemocoagulation disorders, thrombocytopenia, hemophilia);
- kab mob ntawm plab zom movtxoj kev nyob rau theem mob.
Cov lus qhia tshwj xeeb
"Flexen" (tshaj tswm ciab) qhia qhia tau hais tias yuav tsum tau ceev faj heev rau cov neeg mob uas muaj lub raum tsis ua haujlwm, siab, plab zom mov, mob ntsws asthma, haus dej cawv, rhinitis, nrog polyps ntawm lub qhov ntswg mucosa, lub cev qhuav dej, urticaria, haus luam yeeb., daim siab cirrhosis, hyperbilirubinemia, kab mob ntshav, sepsis, ntshav qab zib mellitus, cerebrospinal pathologies, cov neeg laus. Hauv cov txheej txheem ntawm kev kho mob nrog cov tshuaj no, kev saib xyuas lub raum thiab lub siab ua haujlwm yog tsim nyog. Yog tias suppositories "Flexen" raug sau ua ke nrog cov tshuaj tiv thaiv coagulants (heparin), qhov kev pheej hmoo ntawm los ntshav nce. Kev kho mob ntev yog ua tau hauv tsev kho mob nkaus xwb. Tsis txhob haus cawv thaum kho.
Side effect
Koj puas tau muab "Flexen" (tswm ciab)? Cov lus qhia rau kev siv tsis suav nrog kev txhim kho cov kev mob tshwm sim. Nov yog:
- mob taub hau;
- nausea;
- siab kub;
- kiv taub hau;
- ntua;
- poob qab los;
- insomnia;
- plab hnyuv hemorrhages;
- asthenia;
- drowsy;
- conjunctivitis;
- xerophthalmia;
- ntshai;
- cem quav;
- tinnitus;
- tsis nco qab;
- qhov muag tsis pom kev;
- kab mob siab;
- hnov tsis hnov;
- vertigo;
- peripheral neuropathy;
- gastralgia;
- tachycardia;
- transient dysuria;
- hyperemia;
- eczema;
- cystitis;
- nephrotic syndrome;
- Yurethritis;
- photodermatitis;
- laryngeal edema;
- hematuria;
- exudative erythema;
- raum tsis ua haujlwm;
- edematous syndrome;
- daim tawv nqaij khaus;
- tawv nqaij ua xua;
- nce kev ua haujlwm ntawm aminotransferases (alanine thiab aspartate aminotransferases) hauv cov ntshav ntshav;
- ua tsis taus pa;
- rhinitis;
- nosebleed;
- bronchospasm;
- anaphylactic shock.
Kev siv cov tshuaj suppositories tuaj yeem ua rau raws plab, kub hnyiab thiab tenesmus.
Symptoms of drug overdose
tswm ciab "Flexen" yog npaj rau kev siv qhov quav - 1 suppository (100 mg) 1-2 zaug hauv ib hnub. Qhov siab tshaj plaws txhua hnub koob tshuaj ntawm ketoprofen yog 300 mg. Nyob rau hauv cov ntaub ntawv ntawm overdose ntawm cov tshuaj, cov tsos mob hauv qab no tau pom:
- daim siab thiab lub raum tsis ua haujlwm;
- drowsy;
- nausea;
- xiav;
- mob hnyav hauv cheeb tsam epigastric;
- ntuav.
Yog tias pom cov cim saum toj no, cov tsos mob kho tau raug sau tseg. Tsis muaj cov tshuaj tiv thaiv tshwj xeeb. Cov pa roj carbon activated, Sorbex, Medetopek lossis Neointestopan yog cov tshuaj adsorbents. Hemodialysis, yuam diuresis yog txoj kev kho tsis zoo. Cov tshuaj alkalizing tau raug sau tseg los txo cov tsos mob ntawm cov kwj dej hauv lub cev. Yog tias tsim nyog, glucocorticoids tuaj yeem siv. NtawmLub raum tsis ua haujlwm, hemodialysis tau ua. Rau convulsions, Diazepam los yog lwm yam benzodiazepan anticonvulsants raug tshuaj; Nrog hnyav hypotension, plasma hloov pauv tau tswj hwm ("Reopoliglyukin", "Polyglukin", "Enterodez", "Polidez", "Hemodez"). Tus neeg mob yuav tsum tau soj ntsuam tas li rau ob peb hnub, vim tias muaj kev pheej hmoo ntawm kev tshwm sim tom qab ntawm qee qhov kev mob plab hnyuv (los ntshav, ulceration).
Kev sib tham nrog lwm cov tshuaj
Txhim kho cov nyhuv anticoagulants, fibrinolytics, ethanol, antiplatelet agents, txo cov nyhuv ntawm peripheral vasodilators, spironolactone, kev ua tau zoo ntawm uricosuric tshuaj, antihypertensive tshuaj thiab diuretics. Cov tshuaj saum toj no tsis sib haum nrog Tramadol. Kev sib xyaw ua ke ntawm Flexen nrog rau lwm cov tshuaj uas tsis yog-steroidal anti-inflammatory, ethyl cawv, glucocorticosteroids, corticotropin provokes tsim rwj thiab kev loj hlob ntawm gastrointestinal los ntshav. Antacids txo qhov nqus ntawm cov tshuaj. Ob hnub ua ntej qhov kev sim rau cov ntsiab lus ntawm 17-ketosteroids, cov tshuaj raug tso tseg.
"Flexen" nce cov nyhuv hypoglycemic ntawm insulin, nrog rau cov tshuaj hypoglycemic ntawm qhov ncauj. Cov tshuaj myelotoxic nce qhov tshwm sim ntawm hematotoxicity ntawm cov tshuaj. Inducers ntawm microsomal biooxidation nyob rau hauv daim siab (Phenylbutazone, ethanol, tricyclic antidepressants, Phenytoin, Rifampicin, barbiturates) qhib lub biosynthesis ntawm hydroxylated.active metabolites. Kev siv ib txhij ntawm "Flexen" nrog "Sodium Valproate" ua rau ua txhaum ntawm platelet aggregation.
Reviews about tshuaj
Ntau tus neeg mob txaus siab rau lo lus nug ntawm qhov tswm ciab Flexen tiag tiag. Cov lus qhia rau kev siv, tus nqi ntawm cov tshuaj, indications thiab contraindications - cov no yog, ntawm chav kawm, cov ntsiab lus tseem ceeb. Txawm li cas los xij, nws tsim nyog tau txais kev paub txog kev xav ntawm cov kws kho mob tshwj xeeb thiab cov neeg mob txog qhov teeb meem no. Feem ntau cov kws kho mob ntseeg hais tias qhov zoo tshaj plaws analgesic thiab anti-inflammatory tus neeg sawv cev yog Flexen (tswj tswm ciab). Kev tshuaj xyuas cov neeg mob feem ntau (80 mus rau 90%) yog qhov zoo, vim tias qhov ua tau zoo ntawm cov tshuaj, txhim khu kev qha kev kho mob ntawm ntau yam etiology thiab localization, cov nyhuv ntev, thiab kev siv yooj yim. Cov txiaj ntsig zoo tuaj yeem raug sau tseg txij li thawj hnub ntawm kev nkag. Kev tshuaj xyuas tsis zoo txog cov tshuaj feem ntau cuam tshuam nrog cov tsos mob tshwm sim thiab nws cov nqi, txawm li cas los xij, qhov tsis zoo ntawm cov tshuaj no tsis tuaj yeem cuam tshuam nws cov txiaj ntsig siab.
Cov ntsiab lus ntawm kev xa tawm los ntawm chaw muag tshuaj
Cov tshuaj nyob rau hauv daim ntawv ntawm suppositories thiab tsiav tshuaj yog tso tawm nruj me ntsis raws li cov tshuaj. Cov tshuaj gel no muaj yam tsis muaj tshuaj kho.
Storage condition
Khaws kom deb ntawm cov menyuam yaus ntawm qhov kub tsis tshaj 25-30 ° C. Cov txheej txheem ntsuas kub tshwj xeeb siv rau txhua hom kev tso tawm. Hnub tas sij hawm yog qhia rau ntawm lub ntim. Cov tshuaj yuav tsum tsis txhob noj tom qab hnub tas sij hawm!
