Cov tshuaj "Diclofenac" muaj cov nyhuv nyuaj, muaj cov tshuaj tiv thaiv kab mob, tshuaj tua kab mob thiab tshuaj tua kab mob. Vim li no, nws yog ib qho ntawm cov tshuaj nrov tshaj plaws, vim nws yog siv los ua cov tsos mob. Nws qhov kev txiav txim yog tsom rau kev txo qis sai thiab zoo ntawm cov txheej txheem inflammatory, nrog rau kev tshem tawm qhov mob. Tab sis qhov kev txiav txim ntawm "Diclofenac" muaj ib tug downside. Yog tias koj tsis quav ntsej cov cai rau kev siv thiab ntau npaum li cas ntawm cov tshuaj, cov tshuaj muaj kev cuam tshuam loj heev rau cov mucous daim nyias nyias ntawm lub plab zom mov, provoking kev loj hlob ntawm cov teeb meem loj. Yog li ntawd, nws tsim nyog xav txog kev siv tshuaj kom raug, nyob ntawm nws daim ntawv tso tawm.
Kev sib sau thiab tso tawm daim ntawv
"Diclofenac" yog cov tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj (NSAID),uas yog derivative ntawm phenylacetic acid. Cov khoom xyaw nquag ntawm cov tshuaj yog diclofenac sodium, uas tau muab lub npe rau cov tshuaj. Tsis tas li ntawd, cov tshuaj muaj pes tsawg leeg muaj cov khoom siv ntxiv uas txhim kho nws cov txiaj ntsig, thiab tseem ua rau muaj kev faib tawm kom raug hauv cov tshuaj muaj pes tsawg leeg.
Cov tshuaj ntxiv tuaj yeem sib txawv nyob ntawm kev tsim cov tshuaj.
Cov no suav nrog:
- starch;
- methylparaben;
- ethanol;
- dimethyl sulfoxide;
- carbomer;
- Ypropylene glycol;
- sodium hydroxide;
- Ycalcium phosphate;
- magnesium stearate;
- glycerin;
- Ydisodium edetat.
Cov tshuaj muaj nyob rau hauv ntau hom, uas tso cai rau koj xaiv cov kev xaiv uas haum tshaj plaws, nyob ntawm tus kab mob.
Cov ntaub ntawv tseem ceeb ntawm "Diclofenac" nrog cov ntsiab lus ntawm cov khoom xyaw nquag hauv cov tshuaj:
- tablets (25, 50 mg);
- tshuaj txhaj (25 mg / 1 ml);
- qhov quav tso quav (50, 100mg);
- tshuaj pleev rau sab nrauv (10.50mg / 1g);
- qhov muag poob (1 mg / 1 ml).
Pharmacodynamics thiab pharmacokinetics
"Diclofenac", zoo li txhua NSAIDs, yog tus cwj pwm los ntawm kev hais tawm los tiv thaiv kev mob thiab ua kom muaj zog. Thiab tseem cov tshuaj muaj ib tug nruab nrab antipyretic khoom. Lub mechanism ntawm kev txiav txim ntawm "Diclofenac" yog raws li nyob rau hauv lub tsub zuj zuj ntawm cov synthesis ntawm prostaglandins. Tsis tas li, cov tshuaj tiv thaiv platelet aggregation.
Thaum noj tshuaj, qhov mob tshwm sim,thaum sawv ntxov nruj thiab o ntawm cov pob qij txha, nrog rau lawv cov kev ua haujlwm zoo dua qub. Kev siv tshuaj thaum lub sijhawm rov ua haujlwm tom qab phais thiab raug mob txo cov tsos mob tsis zoo thaum txav mus los thiab so.
Cov tshuaj nquag ntawm cov tshuaj sai sai nkag mus rau hauv cov ntshav plasma. Nws qhov siab tshaj plaws yog tsau 1-2 teev tom qab thov. Kev sib txuas lus nrog cov ntshav protein yog 99%.
Diclofenac sodium muaj qib siab nkag mus rau hauv cov ntaub so ntswg thiab mus rau hauv cov kua roj ntsha uas ua rau cov pob qij txha. Qhov siab tshaj plaws concentration yog mus txog tom qab 4 teev tom qab noj. Kev siv cov tshuaj tom qab noj mov qeeb qeeb ntawm cov tshuaj, tab sis tsis cuam tshuam rau nws cov txiaj ntsig. Bioavailability yog 5%.
Lub neej ib nrab yog 1-6 teev nyob ntawm daim ntawv ntawm cov tshuaj. Kwv yees li 30% yog tawm hauv cov quav, hos tus so yog metabolized nyob rau hauv daim siab thiab tawm los ntawm ob lub raum.
Qhov zoo ntawm "Diclofenac" yog tias nws tsis yog tshuaj thiab tsis cuam tshuam rau kev ua pa, tab sis nws muaj qhov ua tau sai thiab muaj zog.
Kev qhia
Kev ua ntawm "Diclofenac" tsis cuam tshuam rau kev loj hlob ntawm tus kab mob, cov tshuaj tsuas yog txo cov tsos mob tsis zoo. Yog li ntawd, nws raug tso cai siv nws tsuas yog ua ib feem ntawm txoj kev kho mob nyuaj raws li kev pom zoo ntawm tus kws kho mob tuaj koom. Tom qab tso tseg cov txheej txheem inflammatory, koj yuav tsum tsis txhob haus cov tshuaj.
Cov lus qhia tseem ceeb rau kev siv:
- kab mob rheumatic;
- mob caj dab ntau yametiology;
- Ankylosing spondylitis;
- osteochondrosis;
- mob nraub qaum;
- kab mob gynecological nrog mob thiab mob (adnexitis, thawj dysmenorrhea);
- ua rau mob gout;
- rehabilitation tom qab raug mob, phais.
Nws tuaj yeem siv los ntxiv rau kev kho mob tseem ceeb rau kev mob hnyav ntawm cov kab mob ua pa sab saud (otitis media, pharyngotonsillitis) kom txo qhov mob.
Kev siv "Diclofenac" purely raws li tshuaj tua kab mob tsis pom zoo.
YContraindications
Ua ntej siv cov tshuaj, koj yuav tsum ua tib zoo kawm cov lus piav qhia uas txuas nrog rau nws. Nws yog ib qho tseem ceeb tshwj xeeb uas yuav tsum tau coj mus rau hauv tus account lub contraindications thiab kev phiv ntawm Diclofenac, uas yuav pab kom tsis txhob muaj teeb meem loj.
Nws txwv tsis pub siv tshuaj:
- nrog tus neeg intolerance rau yam tsawg kawg yog ib qho ntawm cov khoom uas tsim cov tshuaj;
- plab hnyuv lossis plab rwj;
- siab, raum tsis ua haujlwm;
- Crohn's disease;
- kab mob plawv;
- hematopoietic ntshawv siab;
- ulcerative colitis;
- mob hnyav, mob plawv tsis ua hauj lwm.
Nws yog txwv tsis pub siv "Diclofenac" tom qab coronary artery bypass grafting.
Txhua hom kev tso tawm ntawm "Diclofenac" kuj muaj kev txwv hnub nyoog rau kev nkag, tab sis cov ntaub ntawv raug ntau dua yog muab hauv qab no, thaum piav qhia txhua qhov sib cais.
"Diclofenac": kev qhia,kev phiv
Tsis quav ntsej cov contraindications uas twb muaj lawm, nrog rau ntau tshaj qhov tso cai noj txhua hnub, provokes kev loj hlob ntawm cov kev mob tshwm sim. Yog li ntawd, nws yog txwv tsis pub siv tshuaj rau nws tus kheej, vim tsuas yog tus kws kho mob tuaj yeem txiav txim siab txog qib txaus ntshai los ntawm kev noj tshuaj, nyob ntawm tus neeg mob tus yam ntxwv.
Nrog rau kev kho mus ntev, cov kev mob tshwm sim hauv qab no ntawm Diclofenac tau pom:
- kiv taub hau;
- migraine;
- limb tremor;
- rash;
- urticaria.
Thaum cov cim ceeb toom tshwm sim, koj yuav tsum sab laj nrog kws kho mob txhawm rau nrhiav cov tshuaj no hloov. Tsis tas li ntawd, kev siv "Diclofenac" exacerbates hemorrhoids, thiab tseem ua rau muaj kev pheej hmoo ntawm myocardial infarction.
cov lus qhia tshwj xeeb rau kev siv:
- Cov neeg laus yuav tsum noj cov tshuaj no nrog ceev faj, pib nrog qhov tsawg kawg nkaus txhua hnub;
- kho tus qauv yog tsim nyog rau cov neeg mob uas muaj lub siab thiab lub raum tsis ua haujlwm, vim tias nws muaj peev xwm ua kom cov concentration ntawm cov khoom nquag hauv lub cev;
- thaum noj tshuaj ntev, yuav tsum tau saib xyuas cov ntshav;
- cov poj niam uas tab tom npaj cev xeeb tub thiab kho kom muaj menyuam tau raug qhia kom tsis txhob noj cov tshuaj no;
- Lub sijhawm tag nrho ntawm kev kho mob, kev tsav tsheb thiab kev ua haujlwm uas yuav tsum muaj kev saib xyuas siab yuav tsum zam;
- rau ntshav qab zib, kab mob coronary thiab kab mob hlwbTxoj kev kho yuav tsum tau ua raws li kev saib xyuas ntawm tus kws kho mob.
Pills
Daim ntawv ntsiav tshuaj ntawm cov tshuaj yog npaj rau cov neeg laus thiab menyuam yaus hnub nyoog qis dua 14 xyoos. Kev txais tos yog pom zoo thaum noj mov thiab tom qab noj mov, haus dej kom ntau.
Tus kws kho mob tau sau cov koob tshuaj txhua hnub thiab kev tswj hwm, nyob ntawm qhov hnyav ntawm tus kab mob, cov txheej txheem ntawm cov txheej txheem inflammatory thiab lub cev teb rau cov tshuaj. Txhua yam tshuaj rau tus kheej hem muaj teeb meem loj.
Biconvex ntsiav tshuaj yog zaj duab xis-coated nrog lub teeb lossis tsaus txiv kab ntxwv tint. Irregularities ntawm zaj duab xis txheej yog permissible, uas tsis yog ib tug defect. Cov tshuaj yuav tsum tau noj tag nrho, tsis ua txhaum kev ncaj ncees ntawm daim nyias nyias.
Yuav kom txo qis qhov tshwm sim ntawm cov kev mob tshwm sim ntawm cov ntsiav tshuaj Diclofenac, nws raug nquahu kom noj cov tshuaj ntawm qhov tsawg kawg nkaus koob tshuaj thaum pib kho.
Cov kev cai niaj hnub rau cov neeg laus yog 100-150 mg, uas yuav tsum tau haus 3 koob tshuaj txhua 3-4 teev. Txhawm rau kom ua tiav cov txiaj ntsig kho mob ntawm cov ntsiav tshuaj Diclofenac nrog cov tsos mob me thiab kev kho mob ntev, nws txaus. haus 75-100 mg ib hnub twg.
Txoj kev tshuaj ntsuam
daim ntawv ntawm cov tshuaj no yog muaj raws li cov kua ntshiab ntshiab ntim rau hauv 2 ml iav ampoules. Txhua ntawm lawv muaj 50 mg ntawm cov khoom xyaw nquag.
Kev daws rau kev txhaj tshuaj intramuscular tuaj yeem yuav yam tsis muaj kws kho mob tshuaj. haum rau cov neeg laus thiabcov tub ntxhais hluas tshaj 16.
Ntxiv rau cov lus qhia dav dav, cov txiaj ntsig kho mob ntawm Diclofenac txhaj yog siv rau kev raug mob thiab pob txha ntawm cov leeg, cov leeg, pob qij txha, ligaments. Tsis tas li ntawd, cov kev daws teeb meem yog muab los ua ib feem ntawm txoj kev kho mob rau cov kab mob uas tsis muaj kab mob sib kis, nrog kev mob tom qab mob ntawm lub qhov muag los ntawm kev ua haujlwm kom tshem tawm thiab cog lub lens.
Cov txiaj ntsig kho mob ntawm kev txhaj tshuaj Diclofenac yog ua tiav los ntawm kev txhaj tshuaj rau hauv cheeb tsam sab saud ntawm cov leeg gluteal. Nws yog txwv tsis pub siv cov tshuaj intravenously thiab subcutaneously. Ua ntej siv, cov tshuaj yuav tsum tau sov rau lub cev kub los ntawm kev tuav lub ampoule nyob rau hauv xib-teg ntawm koj txhais tes rau ob peb feeb. Qhov no tso cai rau koj los txhim kho cov nyhuv ntawm cov tshuaj thiab ua kom nrawm nkag mus ntawm cov khoom xyaw nquag mus rau qhov chaw mob.
Thoob plaws hauv chav kawm, kev txhaj tshuaj yuav tsum hloov pauv hauv ib lossis lwm lub pob tw. Cov tshuaj yuav tsum tau siv 1 zaug hauv ib hnub, tab sis raws li kws kho mob tau sau tseg, tus nqi ib zaug tuaj yeem ua ob npaug. Cov chav kawm ntawm kev kho mob feem ntau tsis pub tshaj 3 hnub, txawm li cas los xij, hauv cov kab mob hnyav, chav kawm tau txuas ntxiv.
Txhawm rau tiv thaiv cov kev mob tshwm sim los ntawm kev txhaj tshuaj Diclofenac, nws raug nquahu kom txhaj tshuaj txhua hnub, uas yuav txo qis qhov cuam tshuam tsis zoo ntawm cov tshuaj ntawm cov plab hnyuv siab raum thiab cov kua tsib.
Lub qhov quav suppositories
Cov tshuaj suppositories yog npaj rau cov neeg laus thiab menyuam yaus hnub nyoog qis dua 15 xyoos. Lawv yog cov dawb los yog cream cylindric tswm ciab, nyob rau hauv uas tej zaum yuav muaj ib tug ntxeem tauib tug pas nrig thiab ib tug funnel zoo li recess. Cov tshuaj tau muab faib los ntawm kev sau ntawv.
Qhov hnyav ntawm ib suppository yog 2 g, qhov concentration ntawm cov khoom xyaw nquag tuaj yeem yog 5 thiab 10%. Txhua pob ntawm cov tshuaj muaj 6-10 suppositories, uas nyob rau ntawm ib ntsiav tshuaj contour.
Ntxiv rau qhov tseem ceeb ntawm lub tswm ciab "Diclofenac", qhov kev txiav txim uas cuam tshuam nrog kev thaiv cov kab mob inflammatory, yog siv rau hauv kev kho mob ntawm:
- prostatitis;
- mob menses;
- mob ntawm cov appendages, zes qe menyuam;
- adnexitis;
- dysmenorrhea;
- hemorrhoids;
- mob nraub qaum, nraub qaum.
Cov nyhuv suppositories tuaj sai dua piv rau cov tshuaj thiab txhaj tshuaj, lawv muaj cov nyhuv analgesic muaj zog thiab nkag mus ncaj qha rau hauv qhov tseem ceeb ntawm qhov mob. Qhov siab tshaj plaws ntawm cov khoom xyaw nquag yog tsau 1 teev tom qab kev tswj hwm.
Cov tshuaj suppositories yuav tsum tau txhaj tob rau hauv qhov quav tam sim tom qab defecation thiab microclysters. Txoj kev kho mob raug pom zoo kom ua thaum hmo ntuj.
Lub sijhawm ua haujlwm ntawm "Diclofenac" yog 24 teev nrog kev qhia txog cov tshuaj suppositories uas muaj cov khoom xyaw nquag 100 mg. Thaum siv cov tshuaj 50 mg, cov tshuaj yuav tsum tau muab ob zaug ib hnub twg txhua 12 teev. Nyob rau hauv cov ntaub ntawv ntawm tus kab mob hnyav, kev nce hauv ib hnub rau 150 mg tau tso cai.
Lub sijhawm nruab nrab ntawm kev kho mob yog 5 hnub. Tab sis ntawm kev txiav txim siab ntawm tus kws kho mob tuaj koom, kev kho mob tuaj yeem txuas ntxiv mus. Kev mob tshwm sim ntawm suppositories"Diclofenac" yog qhov ua rau qeeb qeeb ntawm kev xav ntawm psychomotor thiab txo qis hauv cov concentration.
Cov tshuaj yuav tsum khaws cia ntawm qhov kub tsis tshaj 25 degrees rau 3 xyoos txij li hnub teeb tsa. Yog tias cov tshuaj tiv thaiv tau tawg thaum lub sijhawm khaws cia, cov tshuaj tsis tuaj yeem siv rau kev kho mob.
Tshuaj pleev rau sab nraud
Nyob rau hauv cov ntaub ntawv no, cov tshuaj yog ib tug dawb ointment nrog ib tug me ntsis creamy tint nrog ib tug me ntsis tsw. Cov tshuaj tau ntim rau hauv cov hlab ntawm 30 g. Qhov concentration ntawm cov khoom xyaw nquag yog 1 lossis 5%. Pom zoo rau cov neeg laus thiab menyuam yaus hnub nyoog qis dua 14 xyoos.
Kev ua hauv zos ntawm Diclofenac ointment yog siv rau ntau yam kev raug mob ntawm ligaments, pob qij txha, tendons, vim bruises, stretch marks thiab lub cev ntau dhau. Nws kuj tseem siv tau cov tshuaj no rau kev mob rheumatoid hauv zos.
Thaum siv cov tshuaj pleev, daim tawv nqaij ua ib hom "reservoir" rau tsub zuj zuj ntawm cov tshuaj, uas tom qab ntawd maj mam tso tawm thiab nkag mus rau hauv qhov tob tob. Qhov concentration ntawm cov khoom xyaw nquag hauv cov ntshav thaum siv cov tshuaj pleev yog 100 npaug tsawg dua thaum noj qhov ncauj.
Nws raug nquahu kom siv cov khoom 3-4 zaug hauv ib hnub. Hauv qhov no, nws yuav tsum maj mam rubbed rau ntawm daim tawv nqaij. Tus nqi ntawm cov tshuaj pleev yog nyob ntawm thaj tsam ntawm thaj tsam o (2-4 g), qhov ntim sib npaug ntawm qhov loj ntawm cov txiv ntoo, qhov no txaus los faib cov khoom ntau dua 400-800 cm2 ntawm thaj chaw. Tus nqi txhua hnub yuav tsum tsis pub tshaj 8 g. Durationsiv cov kws kho mob sau tseg, tab sis tsis pub ntau tshaj 2 lub lis piam nrog kev siv txhua hnub.
Lub txee lub neej ntawm cov tshuaj yog 2 xyoos txij li hnub teeb tsa, thaum tuav lub raj kom ruaj khov.
Nyob zoo ib tsoom niam txiv kwv tij neej tsas sawv daws.
Daim ntawv no ntawm "Diclofenac" yog ib qho kev daws teeb meem uas muaj cov ntsiab lus tseem ceeb ntawm 0.1%. Cov cuab yeej raug muag hauv lub raj mis tshwj xeeb uas muaj lub tshuab xa dej, uas tso cai rau koj siv cov tshuaj yam tsis muaj teeb meem ntau.
Qhov muag dauv yog rau cov neeg laus thiab menyuam yaus hnub nyoog 2 xyoos thiab laus dua. Qhov siab tshaj plaws ntawm diclofenac sodium yog tsau nyob rau hauv conjunctiva thiab cornea 30 feeb tom qab thov. Ib qho tseem ceeb ntawm cov tshuaj tsis nkag mus rau hauv lub cev.
Kev qhia rau kev siv cov tshuaj pleev qhov muag yog:
- tiv thaiv kab mob thaum phais kab mob cataract (1 poob 3-5 zaug hauv ib hnub);
- txo qhov mob thiab photophobia tom qab keratectomy rau 24 teev (1 poob 1 teev ua ntej thiab tom qab phais txhua ib nrab teev, thiab tom qab ntawd 1 poob 4 zaug hauv ib hnub);
- inhibition ntawm miosis thaum phais (1 tee txhua 30 feeb 2 teev ua ntej kev phais thiab tom qab 1 tee 3 zaug nrog tib lub sijhawm).
Lub sijhawm ntawm kev kho mob yog tus kws kho mob tau sau tseg raws li tus kheej tus yam ntxwv ntawm tus neeg mob.
Algorithm rau cov txheej txheem kho:
- ntxuav tes kom huv.
- Tshem lub hau ntawm lub raj thiab txiav tawm qhov kawg ntawm lub tee nrog txiab yam tsis muaj kev puas tsuajxov.
- Tig koj lub taub hau rov qab.
- rub daim tawv muag hauv qab nrog koj tus ntiv tes taw, saib.
- Nqa lub raj tshuaj rau ntawm qhov muag, tig rooj plaub thiab maj mam nias nws, ntws 1 poob.
- Kaw lub qhov muag, hle lub kaum sab hauv ntawm lub qhov muag rau 1-2 feeb, uas yuav tiv thaiv cov tshuaj to.
- Tsis qhib qhov muag, blot nrog paj rwb swab.
- Tom qab ntawd, qhib qhov muag thiab ntxuav koj txhais tes.
Cov txheej txheem yuav tsum tau ua yam tsis txhob kov daim tawv muag thiab cov plaub muag. Tom qab ntawd, nws tsis pom zoo kom tawm mus sab nraud rau 1-1.5 teev.
qhib lub raj mis tuaj yeem khaws cia ntawm qhov kub ntawm 15-25 degrees tsis tshaj 4 lub lis piam.
"Diclofenac" thaum cev xeeb tub thiab lactation
Lub sijhawm cev xeeb tub thiab thaum pub niam mis, txwv tsis pub siv tshuaj. Qhov kev txiav txim ntawm "Diclofenac" yog tshwj xeeb tshaj yog txaus ntshai nyob rau hauv lub 3rd peb lub hlis twg ntawm cev xeeb tub. Qhov no tuaj yeem ua rau qeeb qeeb ntawm kev ua haujlwm vim qhov ua rau lub tsev menyuam tsis muaj zog, nrog rau ua rau cov ntshav tawm ntau thaum yug.
Yog tias tsim nyog, kev siv "Diclofenac" thaum lub sij hawm lactation yuav tsum tsis txhob pub niam mis ib ntus rau tag nrho lub sijhawm kho.
Diclofenac yog cov tshuaj muaj zog thiab siv tau zoo uas tuaj yeem siv los ua thawj pab txhawm rau txo qhov mob sai. Tab sis nws tsis muaj peev xwm tshem tawm qhov tseem ceeb ntawm qhov mob, yog li ntawd, nws raug tso cai siv nws tsuas yog ua ke nrog lwm txoj kev ua ib feem ntawm txoj kev kho mob. Tsis tsim nyogTsis nco qab tias qhov kev txiav txim ntawm "Diclofenac" tuaj yeem ua rau muaj kev phiv, yog li nws yuav tsum tau siv nruj me ntsis raws li kws kho mob cov lus qhia.
