Tib neeg lub cev tiv thaiv kab mob yog ib txoj hauv kev nyuaj. Nws muaj cov hlwb uas tiv thaiv nws los ntawm kev nkag mus ntawm cov kab mob pathogenic microorganisms. Nws kuj tshwm sim tias kev tiv thaiv tsis ua haujlwm thiab nws yuam kev pib tawm tsam cov hlwb ntawm nws lub cev.
kab mob autoimmune
Lymphocytes yog lub luag haujlwm tsim cov tshuaj tiv thaiv kab mob uas thaiv kev ua haujlwm ntawm microbes, kab mob thiab lwm yam kab mob. Ib txhia ntawm lawv yog cov neeg saib mob hlwb. Lawv txoj haujlwm yog txhawm rau rhuav tshem cov ntaub so ntswg ntawm lawv lub cev hauv lawv cov kev hloov pauv pathological. Raws li kev cuam tshuam ntawm qee yam, lub kaw lus yuav ua tsis tiav. Hauv qhov no, lymphocytes pib tua cov hlwb noj qab haus huv, pib cov txheej txheem ntawm kev puas tsuaj rau lub cev.
Qhov laj thawj rau lawv tus cwj pwm nruj tuaj yeem yog sab hauv thiab sab nraud. Rau thawjhais txog kev yug me nyuam. Gene mutations tuaj yeem dhau los ntawm ib tiam dhau ib tiam. Yog li, yog tias cov poj koob yawm txwv raug kev txom nyem los ntawm cov kab mob autoimmune, qhov tshwm sim ntawm qhov tshwm sim yog siab heev.
Cov laj thawj sab nraud yog:
- negative ib puag ncig cuam tshuam;
- mob hnyav thiab ncua sij hawm ntawm cov kab mob sib kis.
Ntxiv rau, qee kis, lymphocytes tsis tuaj yeem paub qhov txawv ntawm lawv tus kheej hloov pauv ntawm cov kab mob thiab tawm tsam ob qho tib si.
Muaj ntau yam kab mob autoimmune nrog cov tsos mob sib txawv. Lawv qhov tshwj xeeb nkaus xwb yog qhov kev loj hlob zuj zus thoob plaws ib tus neeg lub neej.
Cov kab mob autoimmune feem ntau yog:
- mob caj dab rheumatoid;
- ntau yam sclerosis;
- mob ntshav qab zib hom 1;
- vasculitis;
- Ylupus erythematosus;
- pemphigus;
- Gaves' thyroiditis;
- myasthenia gravis;
- scleroderma;
- antiphospholipid syndrome;
- Crohn's disease;
- Yglomerol nephritis;
- vitiligo;
- psoriasis;
- myocarditis, thiab lwm yam.
Cov npe ntawm cov kab mob autoimmune ntev heev. Yog tsis muaj kev kho mob, feem ntau ntawm lawv ua rau muaj kev phom sij loj rau ob qho tib si kev noj qab haus huv thiab lub neej ntawm tus neeg mob. Kev kuaj mob raws sij hawm yog qhov tseem ceeb heev. Lub luag haujlwm tseem ceeb yog ua los ntawm kev muaj peev xwm ntawm tus kws kho mob tuaj koom, uas tau ntau xyoo tuaj yeem tsis xav tias muaj cov kab mob autoimmune. Yog tias nws tsis ntseeg qhov kev kuaj mob, thiab cov tsos mob ceeb toomkev txhawj xeeb ntxiv mus, nws raug pom zoo kom hu rau lwm tus kws tshaj lij thiab pub ntshav rau kev tshuaj ntsuam.
Nyob hauv chav kuaj thaum lub sijhawm tshawb fawb kawm cov cim ntawm cov kab mob autoimmune. Yog tias qhov nce hauv qib ntawm ib qho ntawm lawv lossis ob peb zaug tau kuaj pom, qhov no qhia txog kev txhim kho ntawm pathology.
Muaj ntau yam cim ntawm tus kab mob autoimmune. Cov hauv qab no yog cov uas muaj qhov txawv txav feem ntau piv rau lwm tus.
Ntau tus cim rau cov thyroid peroxidase
Tsis yog qhov kev tshuaj ntsuam xyuas ib txwm yog qhov qhia txog kab mob txaus ntshai. Cov thyroid peroxidase yog cov thyroid enzyme. Kev nce me ntsis hauv nws cov concentration yuav yog qhov tshwm sim ntawm kev puas siab puas ntsws-kev xav, kev phais thiab kev kho lub cev hauv lub caj dab. Tsis tas li ntawd, nws qib nce nrog cov thyroid pathologies.
Yog tias tus cim kab mob autoimmune AT TPO tau nce siab thiab ntev ntev, qhov no ua rau nws muaj peev xwm xav tias muaj cov thyroid hypothyroidism. Qhov no pathology yog tus cwj pwm los ntawm kev puas tsuaj rau cov thyroid caj pas los ntawm nws tus kheej lub cev tiv thaiv kab mob. Raws li qhov tshwm sim, nws txoj haujlwm raug cuam tshuam, uas tuaj yeem ua rau muaj kev ua haujlwm tsis zoo ntawm ntau lub cev thiab lub cev.
nce qib ntawm tus kab mob autoimmune tus cim AT TPO kuj tseem qhia tau tias:
- lwm hom thyroiditis;
- mob raum tsis ua haujlwm;
- mob ntshav qab zib;
- rheumatism;
- raug mob rau cov kabmob ntawm cov kabmob endocrine;
- Basedowkab mob;
- postpartum thyroid disorders.
Kev kuaj mob kom raug yog nyob ntawm qhov concentration ntawm cov tshuaj tiv thaiv hauv cov ntshav. Yog tias kuaj pom tus kab mob autoimmune, nws txoj kev kho yuav yog siv tshuaj hormonal.
Gliadin marker nce
Kev nce ntxiv ntawm cov tshuaj immunoglobulins G thiab A tuaj yeem yog ib qho kev qhia ntawm cov kab mob sib txuas, kab mob hauv lub ntsws, kab mob maladaption. Tab sis feem ntau, qhov ntsuas siab ntawm tus kab mob autoimmune yog qhov qhia txog kab mob celiac. Nrog rau qhov pathology no, cov mucous daim nyias nyias ntawm txoj hnyuv me raug cuam tshuam, uas yog qhov pib ua rau cov txheej txheem nplaum thiab ntau yam kev hloov dystrophic. Txhawm rau txhim kho tus mob, yuav tsum ua raws li kev noj zaub mov tsis muaj gluten nruj.
cov tshuaj insulin nce ntxiv
Cov tshuaj tiv thaiv kab mob (AT) rau cov tshuaj hormone no qhia txog kev puas tsuaj ntawm pancreatic cells. Qhov nce ntawm tus cim ntawm tus kab mob autoimmune hauv qhov no qhia tias muaj ntshav qab zib hom 1. Qhov tshwm sim ntawm kev txhim kho ntawm cov kab mob no yog qhov tsis muaj insulin.
Rau qhov kev kuaj mob kom raug, yuav tsum pub ntshav rau kev tshuaj ntsuam. Yog tias cov piam thaj hauv nws nce ntxiv, ces qhov pom ntawm tus kab mob tau lees paub. Raws li txoj cai, cov neeg mob ntshav qab zib hom 1 raug kev txom nyem los ntawm ntau yam kab mob autoimmune ib zaug.
Ntau tus cim rau thyroglobulin
Raws li kev soj ntsuam, nws tseem tuaj yeem kuaj xyuas cov kab mob oncological. Thyroglobulin yog cov protein ua ntej rau cov thyroid hormones. Kev soj ntsuam nws qib tso cai rau kuaj pom ntau yam kab mob ntawm lub cev thaum ntxov.
Yog tias tus cim kab mob autoimmune AT TG nce siab, qhov no yuav qhia tau tias:
- Graves' kab mob;
- Hashimoto's thyroiditis;
- mob qog noj ntshav;
- diffuse non-toxic goiter.
Kev tshuaj ntsuam tsis yog qhia rau kev ntsuas qhov ua tau zoo ntawm kev kho mob.
Ntau dua ob-stranded DNA marker
Cov txiaj ntsig zoo li no yuav qhia tau tias muaj kab mob lupus erythematosus. Qhov no yog ib hom kab mob autoimmune, uas yog nrog los ntawm kev puas tsuaj rau cov hlab ntsha thiab cov ntaub so ntswg.
Ntxiv rau qhov nce qib ntawm tus cim rau ob-stranded DNA, qib ntawm cov tshuaj tiv thaiv rau:
- lupus anticoagulant;
- antinuclear yam;
- cardiolipin (chav kawm G thiab M);
- Nucleosomes.
Yog tias cov cim kab mob autoimmune no nce siab, qhov no kuj yuav yog ib qho cim:
- rheumatism;
- myelitis;
- hemolytic anemia;
- mob leukemia;
- mob siab rau daim siab pathologies;
- autoimmune kab mob siab;
- plasmocytomas;
- scleroderma, thiab lwm yam.
Prothrombin marker nce
Cov tshuaj no ua haujlwm ua cov ntshav txhaws. Cov tshuaj tiv thaiv rau nws cuam tshuam cov txheej txheem, ua rau cov ntshav txhaws.
YogQhov no cim ntawm tus kab mob autoimmune yog siab, qhov no yog ib qho cim ntawm antiphospholipid syndrome. Lub sij hawm yog siv rau tag nrho pab pawg ntawm cov teeb meem:
- Ysystemic scleroderma;
- Ylupus erythematosus;
- mob caj dab rheumatoid;
- kab mob phem.
Qhov no yog vim cov tshuaj tiv thaiv uas tsim los ntawm lub cev tiv thaiv kab mob thiab rhuav tshem phospholipids uas yog ib feem ntawm cov cell membranes.
Tsis tas li, nrog kev nce ntxiv hauv cov cim rau prothrombin, qhov tshwm sim ntawm myocardial infarction nce ntau.
In xaus
Lub luag haujlwm tseem ceeb ntawm tib neeg lub cev tiv thaiv kab mob yog los tiv thaiv nws los ntawm kev ua ntawm cov kab mob pathogenic. Lymphocytes yog lub luag haujlwm rau cov txheej txheem no. Raws li kev cuam tshuam ntawm lwm yam los yog vim muaj kev hloov pauv ntawm cov noob los ntawm ib tiam dhau ib tiam, kev ua tsis tiav loj tuaj yeem tshwm sim hauv kev ua haujlwm ntawm lub cev. Yog li ntawd, cov tub rog tiv thaiv pib tawm tsam lawv cov hlwb. Txog niaj hnub no, ntau yam kab mob autoimmune paub, uas, yog tias tsis kho raws sijhawm, tuaj yeem ua rau muaj teeb meem loj.
