Flupirtine maleate yog ib yam tshuaj uas muaj tshuaj tua kab mob thiab yog ib feem ntawm ntau cov tshuaj los ntawm qeb ntawm cov tshuaj uas tsis yog tshuaj opioid. Nws muaj cov nyhuv analgesic, uas tshwm sim vim kev xaiv ua kom tsis muaj zog ntawm cov poov tshuaj keeb kwm. Tsis tas li ntawd, flupirtine muaj ib qho kev tsis txaus siab ntawm cov leeg nqaij so thiab cov nyhuv neurotropic. Cov tshuaj feem ntau yog Katadolon, eponymous Flupirtine thiab Nolodatak. Cov lus qhia rau kev siv tom kawg yuav qhia hauv qab no.
Qhov no yog ib qho uas tsis yog-opioid hauv nruab nrab ua tshuaj tua kab mob. Flupirtine (cov tshuaj nquag ntawm cov tshuaj) yog ib tus neeg sawv cev ntawm cov chav kawm ntawm kev xaiv cov activators ntawm neuronal potassium raws. Tsis ua rau muaj kev quav yeeb quav tshuaj thiab kev quav yeeb quav tshuaj, muaj cov leeg nqaij so.
Cov nyhuv antispastic ntawm cov leeg yog cuam tshuam nrog kev thaiv kev sib kis ntawm excitation mus rau lub cev muaj zog neurons thiab intercalaryneurons ua rau tso tawm cov leeg nro. Cov nyhuv no ntawm Nolodataku yog tshwm sim nyob rau hauv ntau cov kab mob ntev nrog rau cov leeg mob spasms (musculoskeletal mob nyob rau hauv lub caj dab thiab nraub qaum, arthropathy, nro taub hau, fibromyalgia).
Cov lus qhia siv rau "Nolodatak" lees paub qhov no.
Composition
Daim ntawv nrov tshaj plaws ntawm flupirtine maleate yog cov ntsiav tshuaj ntawm qhov ncauj. Ib ntsiav tshuaj muaj 100 mg. active tivthaiv. Cov khoom pabcuam hauv kev npaj raws li flupirtine, raws li txoj cai, yog magnesium stearate, gelatin, purified dej, copovidone, calcium hydrogen phosphate dihydrate, colloidal silicon dioxide, thiab lwm yam.
Properties
Flupirtine maleate muaj cov nyhuv analgesic thiab suav nrog hauv pab pawg ntawm cov tshuaj tsis yog opioid. Cov khoom ua haujlwm hauv nruab nrab. Flupirtine yog ib qho kev xaiv nruab nrab potassium channel activator. Thaum noj tshuaj raws li cov tshuaj pharmacological no, lawv tsis cuam tshuam nrog cholinergic receptors thiab adrenoreceptors.
Raws li cov lus qhia rau kev siv rau flupirtine maleate, cov khoom no tso cai rau nws kom muaj cov nyhuv analgesic. Tawm tsam keeb kwm yav dhau los ntawm kev xaiv qhib ntawm nruab nrab cov kab hluav taws xob nrog kev tso tawm ib txhij ntawm cov poov tshuaj ions, tus so ntawm cov neuron yog normalized. Cov tom kawg tsis tas yuav mob heev thiab excitable. Yog li, nws muaj peev xwm ua kom tau txais kev kho mob sai saisyndrome, qhia nyob rau hauv me me los yog mob hnyav. Flupirtine kuj muaj cov leeg nqaij so, uas yog, nws muaj cov nyhuv sedative.
Kev qhia
Flupirtine maleate thiab tshuaj raws li nws tau sau tseg kom tshem tawm qhov mob mob tshwm sim los ntawm ntau yam, suav nrog:
- mob khaub thuas tsis tu ncua nrog mob hauv plab plab.
- Mob ntawm hom neuropathic tom qab raug mob.
- Cov leeg nqaij spasms thiab kuj fibromyalgia.
- mob taub hau vim kev tawm dag zog ntau dhau.
- kab mob Oncological, tshwm sim los ntawm qhov mob syndrome.
- Rehabilitation lub sij hawm tom qab phais.
YContraindications
Lub hauv paus ua yeeb yam analgesic flupirtine yog contraindicated nyob rau hauv cov neeg mob uas muaj cov nram qab no comorbid mob thiab pathologies:
- Pathological txheej txheem hauv siab.
- Cov menyuam yaus hnub nyoog qis dua 18.
- Kev quav dej quav cawv hauv daim ntawv ntev.
- Cov neeg mob uas muaj keeb kwm ntawm kev ua rau lub raum encephalopathy.
- Tawm tsam keeb kwm ntawm kev siv tib lub sijhawm nrog cov tshuaj uas muaj cov nyhuv hepatotoxic.
- Performed tinnitus therapy.
- Ib tus neeg cov tshuaj tiv thaiv rau flupirtine lossis ib feem ntawm kev npaj raws li cov tshuaj nquag no.
Nyob rau hauv lub sijhawm teem tshuaj nrog flupirtine rau cov neeg mob laus, yuav tsum tau ceev faj ntxiv, thiabnrog rau kev kho ntau npaum li cas. Raws li qhov pom ntawm nws cov khoom sedative, tawm tsam keeb kwm yav dhau los ntawm kev kho mob flupirtine, nws tsis pom zoo kom tsav tsheb, nrog rau kev ua haujlwm uas yuav tsum tau ua kom muaj zog ntxiv thiab qhov tseeb ntawm kev ua haujlwm.
Teratogenic nyhuv ntawm flupirtine tsis tau txheeb xyuas, txawm li cas los xij, nws tsis raug pom zoo siv los ntawm cov poj niam thaum cev xeeb tub. Qhov no kuj yog vim tsis muaj cov ntaub ntawv kho mob ntawm kev nyab xeeb ntawm flupirtine hauv ntau yam kev npaj rau tus menyuam hauv plab.
Yog tias tus poj niam tau txais tshuaj flupirtine thaum lub sijhawm lactation, nws raug nquahu kom tsis txhob pub niam mis rau lub sijhawm kho. Qhov no yog vim lub fact tias nyob rau hauv lub chav kawm ntawm kev tshawb fawb ntawm cov tshuaj, nws cov cuab yeej tau tsim los nkag mus rau hauv me me rau hauv cov mis nyuj.
Kev qhia
Flupirtine hauv ntsiav tshuaj daim ntawv npaj rau kev tswj qhov ncauj. Capsules tsis tau zom thiab ntxuav nrog dej me me. Txij li cov tshuaj tua kab mob flupirtine feem ntau tau muab rau cov neeg mob uas mob hnyav, qhib lub tshuaj ntsiav thiab qhia cov tshuaj los ntawm lub raj tso cai. Nyob rau hauv cov ntaub ntawv no, lub iab saj ntawm cov tshuaj yuav tsum tau coj mus rau hauv tus account, yog li nws yuav tsum tau neutralized los ntawm kev noj cov txiv hmab txiv ntoo qab zib, xws li txiv tsawb. Yuav luag tag nrho cov tshuaj raws li flupirtine tau noj raws li tib lub tswv yim, uas yog vim tib lub ntsiab lus ntawm cov tshuaj hauv cov ntsiav tshuaj, sib npaug li 100 mg. Cov lus pom zoo hauv qab no tau ua raws:
- qauv noj ntawm flupirtine maleateKev noj tshuaj 300-400 mg ib hnub, muab faib ua 3-4 zaug. Yog hais tias qhov mob syndrome tau hais, qhov ntau npaum ntawm cov tshuaj tuaj yeem ua ob npaug. Qhov siab tshaj plaws noj txhua hnub ntawm flupirtine yuav tsum tsis pub tshaj 600 mg.
- Cov tshuaj noj yog xaiv tus kheej, suav nrog tus kheej tus yam ntxwv ntawm tus neeg mob thiab qhov mob hnyav ntawm qhov mob. Lub sijhawm ntawm kev kho mob nrog flupirtine yuav tsum tsis txhob ntev tshaj li ob lub lis piam. Qhov no xaiv qhov tsawg kawg nkaus cov tshuaj kho mob uas muaj cov txiaj ntsig zoo.
- Nyob rau hauv cov neeg laus, nyob rau theem pib ntawm kev kho mob, qhov tsawg kawg nkaus koob tshuaj ntawm 100 mg ntawm flupirtine yog teem rau sawv ntxov thiab yav tsaus ntuj.
Tawm tsam keeb kwm ntawm lub raum tsis ua haujlwm, nws yog ib qho tsim nyog yuav tsum tau saib xyuas qib ntawm creatinine hauv cov ntshav plasma. Qhov siab tshaj plaws noj txhua hnub rau cov neeg mob nrog qhov kev kuaj mob no yuav yog 300 mg ntawm flupirtine. Yog tias lub raum tsis txaus yog qhov mob me me lossis nruab nrab, tsis tas yuav hloov kho cov tshuaj noj. Nrog hypoalbuminemia, kev teem caij ua raws li tus qauv zoo ib yam li tawm tsam keeb kwm ntawm lub raum tsis ua haujlwm.
Kev sau cov tshuaj hauv ntau npaum li cas cov txheej txheem kho mob yuav tsum tau ua tib zoo saib xyuas kev kho mob, thiab qee zaus mus pw hauv tsev kho mob ntawm tus neeg mob.
Puas muaj kev phiv ntawm flupirtine txiv neej?
Side effects
Tawm tsam keeb kwm yav dhau los ntawm kev noj cov tshuaj flupirtine, cov teebmeem hauv qab no tuaj yeem tshwm sim:
- tawv nqaij - hyperhidrosis.
- Nervous system - pw tsaug zog cuam tshuam, kev nyuaj siab,kiv taub hau, mob taub hau, nyob tsis tswm thiab nervousness, tsis meej pem.
- Daim siab thiab kab mob biliary - daim siab tsis ua hauj lwm, siab siab transaminases, kab mob siab.
- Kev pom kev pom kev tsis pom kev.
- plab thiab hnyuv - flatulence, mob hauv plab, dyspeptic mob, cem quav, xeev siab thiab ntuav, raws plab, dryness ntawm qhov ncauj mucosa.
- Immune system - hypersensitivity rau flupirtine, qhia nyob rau hauv ib qho kev tsis haum tshuaj nyob rau hauv daim ntawv ntawm pob khaus, khaus, urticaria thiab kub taub hau.
- Lwm tus - cuam tshuam tsis qab los txog rau nws qhov kev poob tag, qaug zog thiab tsis muaj zog, tshwj xeeb tshaj yog hais thaum pib ntawm kev kho mob flupirtine.
Cov tshuaj tiv thaiv tsis zoo rau flupirtine qhia, raws li txoj cai, ib qho kev xaiv tsis raug thiab yuav tsum tau hloov kho. Ib qho kev zam yog kev ua xua rau cov tshuaj nquag, uas cuam tshuam nrog kev tshem tawm cov tshuaj thiab xaiv cov tshuaj analogue. Tag nrho lwm cov tsos mob ploj mus ntawm lawv tus kheej tom qab kho.
Cov tsos mob ntau dhau
Tawm tsam keeb kwm yav dhau los ntawm kev noj tshuaj ntau dhau ntawm flupirtine, cov tsos mob hauv qab no tuaj yeem tshwm sim:
- Tachycardia.
- Kev tsis sib haum xeeb.
- Nausea.
Kev noj ntau dhau yog kho los ntawm plab hnyuv thiab tom qab noj cov enterosorbents. Kev kho mob ntxiv yog ua tiav.
Analogues
Muaj ntau yam tshuaj uas muaj qhov sib xwskho cov nyhuv ntawm cov tshuaj. Feem ntau yog cov nram qab no analogs ntawm flupirtine maleate:
- "Dexalgin".
- "Dimexide".
- Ketanov.
- Bupranal.
- Promedol.
- Lidocaine.
- Metindol.
Ua ntej hloov ib qho tshuaj nrog lwm tus, koj yuav tsum sab laj nrog koj tus kws kho mob, txij li thaum muab tshuaj flupirtine, nws tso siab rau tus neeg mob tus mob thiab nws tus yam ntxwv. Ib qho analogue tej zaum yuav muaj qhov sib txawv ntawm qhov sib txawv thiab, raws li, xav tias qhov kev txais tos sib txawv.
Reviews
Kev tshuaj xyuas ntawm kev noj cov tshuaj flupirtine maleate hauv ntau qhov kev npaj yog qhov zoo heev. Rau ntau tus, nws yuav pab daws tau txawm tias qhov mob syndrome ntawm kev siv zog ntau ntxiv. Flupirtine-based tshuaj feem ntau raug muab rau cov neeg mob qog noj ntshav thaum lwm cov tshuaj ua tsis tau tiav.
Flupirtine maleate tuaj yeem siv los ua ib yam tshuaj, nrog rau kev sib xyaw nrog opioid thiab tsis-steroidal tshuaj tiv thaiv kab mob. Nws tseem raug tso cai noj flupirtine ib txhij nrog cov tshuaj tiv thaiv kev nyuaj siab.
Hauv kev tshuaj xyuas, muaj kev tsis txaus siab los ntawm cov neeg mob noj flupirtine txog qhov tsos ntawm xeev siab thiab tsis muaj zog thaum pib ntawm kev kho mob. Txawm li cas los xij, tib cov neeg mob hais tias tom qab ob peb hnub, cov tsos mob tsis zoo no ploj mus ntawm lawv tus kheej. Cov kws kho mob feem ntau siv flupirtine rau cov neeg mob uas mob hnyav.
