Ntau tus neeg paub tias ntshav ntshav yog ib yam kab mob txaus ntshai heev. Muaj ntau ntau hom kab mob no, thiab txhua tus ntawm lawv muaj kev phom sij rau tib neeg kev noj qab haus huv. Sideroblastic anemia yog ib qho txaus ntshai pathology cuam tshuam nrog kev ua txhaum ntawm kev sib txuas ntawm cov kab mob. Hauv cov kab mob no, cov pob txha pob txha siv hlau los ua ke hemoglobin, yog li nws tau tso rau hauv cov kabmob sab hauv. Qhov tseem ceeb tshaj plaws yog kom tsis txhob muaj teeb meem, thiab rau qhov no nws yog ib qho tsim nyog los nrhiav kev pab los ntawm tus kws kho mob kom raws sijhawm.
Txoj kev xav
Sideroblastic anemia txawv ntawm lwm hom kab mob los ntawm kev txo qis ntawm cov hlau hauv cov qe ntshav liab. Qhov tseeb yog tias cov pob txha pob txha tsis siv cov khoom no hauv kev sib txuas ntawm hemoglobin. Feem ntau, tus kab mob no tshwm sim raws li congenital los yog kis tau. Nyob rau theem genetic, anemia feem ntau tshwm sim hauv cov tub.
Tus kab mob no kuj kis tau los ntawm autosomal dominant yam. Qhov no anemia hu ua Pearson's syndrome. Thaum hlau yog absorbed tsis zoo nyob rau hauv lub cev, nws yog deposits nyob rau hauv lub sab hauv nruab nrog cev, uas ua rau ib tug sideroblastic anemia. Yog tias muaj hlau ntau dhauKev ua haujlwm ntawm lub siab, ob lub raum thiab lub plawv cov leeg raug cuam tshuam.
Nyob ntawm kab mob
Anemia ntawm hom no yog faib raws li qib ntawm qhov hnyav, nrog rau vim li cas rau qhov tsos thiab daim duab kho mob. Muaj ntau ntau hom kab mob sideroblastic anemia:
- Hereditary. Tus kab mob no tau txais txiaj ntsig los ntawm kev hloov pauv ntawm cov noob. Qhov no pathology yog tshwm sim los ntawm ib qho anomaly ntawm cov txheej txheem metabolic nrog kev koom tes ntawm vitamin B6 thiab aminolevulinic acid. Tus kab mob no ua rau nws tus kheej hnov tom qab yug los lossis thaum hluas.
- Nyob. Daim ntawv no yog cais cais, txawm tias qee qhov nws belongs rau hom kab mob. Nws yog tus cwj pwm los ntawm cov ntsiab lus siab ntawm erythrocyte coproporphyrin.
- muas. Pom tshwm sim los ntawm qhov tsis zoo ntawm cov tshuaj. Ntawm lawv, ethanol, lead, cyclosirin raug cais tawm.
Teeb meem nrog cov hlau synthesis kuj tshwm sim vim cov txheej txheem qog hauv lub cev. Kwv yees li ntawm 1/10 ntawm cov neeg mob uas muaj kab mob sideroblastic anemia raug mob leukemia.
Tus kab mob
Qhov laj thawj tseem ceeb rau kev loj hlob ntawm tus kab mob no yog qhov tsis muaj protoporphyirin, uas yog ib qho ntawm cov khoom sib txuas ntawm cov ntsiab lus tseem ceeb ntawm hemoglobin. Ntxiv nrog rau cov khoom no, cov protein thiab hlau kuj koom nrog hauv kev tsim.
Tau txais daim ntawv ntawm sideroblastic anemia tshwm sim vim qhov tseeb tias lub cev tsis tau txais cov khoom tsim nyog hauv qhov ntau txaus. Muaj qee lub sij hawm thaum cov tshuaj raug txwv los ntawm cov tshuaj uas tus neeg noj.
Lub cev yog depleted los ntawm cov cawv. Anemia tuaj yeem tshwm sim vim muaj cov tshuaj lom neeg txhuas lossis siv cov tshuaj tua kab mob muaj zog. Daim ntawv keeb kwm yog kis los ntawm poj niam chromosome nrog cov noob puas. Tsis tas li ntawd, qhov ua rau ntawm tus kab mob tuaj yeem ua rau lub cev tsis zoo thiab kev loj hlob ntawm cov txheej txheem qog.
Kev kuaj mob ntawm sideroblastic anemia
Tus txheej txheem ntawm kev kuaj tus kab mob no nyuaj heev, vim nws yuav luag asymptomatic. Ntxiv mus, tsis muaj cov duab kho mob uas yuav tsum tau tso siab. Yog tias koj saib tsuas yog cov cim qhia sab nraud, ces nws tsis muaj tseeb los kuaj tus kab mob no. Txawm li cas los xij, muaj ib txoj hauv kev los txheeb xyuas cov kab mob sideroblastic anemia - kuaj ntshav.
Nws kuj tau xyaum los tshuaj xyuas tus neeg mob lub cev sab hauv kom pom cov hlau tso nyiaj. Tab sis los ntawm lub sij hawm no, lub caij yog twb ua rau cov tsos mob hematological. Txhawm rau kom tsis txhob yuam kev, nws yog ib qho tsim nyog kom paub meej qhov kev kuaj mob. Qhov no yog ua tiav los ntawm kev soj ntsuam macroscopic ntawm cov pob txha.
Yuav kom txo qhov kev pheej hmoo tsawg, yuav tsum muaj kev kuaj ntshav. Nws yog cov txheej txheem no uas yog txoj hauv kev zoo tshaj plaws los txiav txim siab sideroblastic anemia. Nws yog ua raws li hauv qab no: lub biopsy yog preliminarily stained nrog ib tug tshwj xeeb tshuaj, thiab yog hais tias unsynthesized hlau yog kuaj, cov yam ntxwv tebchaw yuav pom.
Kuv yuav tsum hu rau tus kws tshwj xeeb twg?
Raws li twb tau sau tseg lawm, cov tsos mob ntawm sideroblastic anemia tsis tau txiav txim siab. Daim duab kho mobtseem ploj lawm, thiab vim li no, qee qhov teeb meem tshwm sim. Yog tias ib tug neeg xav tias qaug zog, tsis muaj zog hauv lub cev, ces, raws li txoj cai, nws tig mus rau tus kws kho mob. Qhov no yog tus kws kho mob uas, yog tias xav tias muaj ntshav qab zib, rov coj tus neeg mob mus rau tus kws kho mob hematologist uas ua qhov kev kuaj mob.
Ua ntej, tus kws kho mob pom zoo kom paub txog cov xwm txheej ntawm tus neeg mob, xav txog kev ua neej nyob, muaj tus cwj pwm tsis zoo, daim ntawv teev cov kab mob yav dhau los, thiab lwm yam. Yog tias tus kws kho mob pom tias tsim nyog, nws yuav ua ntau yam kev tshawb fawb. Cov no suav nrog:
- kuaj ntshav (general thiab biochemical);
- siab biopsy;
- tsom xam ntawm cov cellular muaj pes tsawg leeg ntawm cov pob txha pob txha.
Hematologist, yog tias tsim nyog, tuaj yeem xa tus neeg mob mus rau lwm tus kws kho mob tshwj xeeb rau kev kuaj kom tiav. Piv txwv li, txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm, koj yuav tsum tau saib xyuas cov kab mob ntshav qab zib). Tus kws kho mob no yuav txiav txim siab seb puas muaj hom kab mob tshwm sim ntawm sideroblastic anemia. Koj kuj yuav tau mus ntsib kws kho mob gynecologist, urologist lossis proctologist.
Kev kho mob
Ua ntej pib kho, nws yog ib qho tsim nyog los txiav txim seb puas muaj hlau tso tawm tiag tiag. Rau qhov no, ib qho kev xeem desferal yog siv. Nws tau muab tshuaj intramuscularly, thiab vim li ntawd, txog 0.5-1.1 mg ntawm cov hlau yuav tsum tau tawm hauv cov zis, thiab nrog hypochromic, hypersideremic, sideroachrestic, sideroblastic anemia - 5-10 mg.
Nws tsim nyog sau cia tias daim ntawv keeb kwm ntawm tus kab mob tuaj yeem kho tauua tsis tau. Txhawm rau txhawm rau cov noob uas tau pib hloov pauv, kev kho mob nrog cov tshuaj vitamin B6 siab feem ntau yog siv. Nws yog siv nyob rau hauv ib tug npaum li ntawm 100 mg ib hnub twg. Txawm li cas los xij, cov tshuaj tiv thaiv ntawm lub cev ntawm no yog yuav luag tsis paub txog. Hauv cov txheej txheem ntawm kev kho mob sideroblastic anemia, qib hemoglobin yuav tsum nce mus rau qib ib txwm nyob hauv peb lub hlis. Yog tias tsis muaj kev txhim kho nyob rau lub sijhawm no, kev kho ntxiv yog qhov tsis muaj txiaj ntsig.
Ntau zaus tus kab mob no tshwm sim los ntawm kev lom tshuaj txhuas. Txhawm rau tiv thaiv qhov no, yuav tsum tau saib xyuas thaum tuav cov tshuaj no. Thaum rov tsim cov tsev qub, yuav tsum tau ceev faj, yog tias ua tau, tshem cov menyuam yaus ib ntus. Tsis txhob hlawv lossis faus cov xim muaj hlau lead. Nws yog qhov zoo tshaj rau khawb los yog tshem tawm cov tshuaj. Tsis tas li ntawd, koj yuav tsum tau ua tib zoo saib xyuas qhov huv ntawm thaj chaw nyob, ua raws li kev tsim kho thiab kev huv huv.
Nws tsis tuaj yeem kho tus kab mob caj ces. Txhawm rau kom muaj txiaj ntsig zoo, nws yog ib qho tsim nyog yuav tsum saib xyuas cov ntshav tas li, tshwj xeeb tshaj yog qib hemoglobin. Qhov no tau ua tiav los ntawm kev ua haujlwm tsis tu ncua ntawm kev kho mob uas tsis tso cai rau tus kab mob no tuaj yeem txhim kho thiab tswj tus neeg mob ib txwm muaj.
