Duhring's dermatitis yog dab tsi? Koj yuav tau txais cov lus teb rau lo lus nug no los ntawm cov ntaub ntawv ntawm cov lus nug. Koj tseem yuav kawm paub kho tus kab mob li cas, nws cov tsos mob thiab ua rau dab tsi.
Cov ntaub ntawv tseem ceeb
Dühring's dermatitis yog ib yam kab mob uas muaj nyob rau hauv pawg dermatoses thiab cais raws li herpetiform. Cov pab pawg no suav nrog cov kab mob ntawm daim tawv nqaij uas tsim los ntawm ntau yam, tab sis muaj tib daim duab kho mob.
Zoo li lwm yam kab mob dermatoses, Duhring's dermatitis yog tus cwj pwm los ntawm qhov tshwm sim ntawm cov pob liab liab. Qhov no pathology yog tsis tshua muaj. Txhua tus neeg ntawm txhua lub hnub nyoog tuaj yeem ntsib nws. Tus kab mob no muaj npe tom qab tus kws kho mob Philadelphia - Duhring. Raws li koj paub, nws tau kawm thaum kawg ntawm lub xyoo pua 19th.
Vim txoj kev loj hlob
Vim li cas Dühring's dermatitis tshwm sim? Qhov tseeb ua rau kev loj hlob ntawm tus kab mob no tseem tsis tau tsim. Txawm li cas los xij, cov kws tshaj lij tau tshaj tawm ntau qhov kev xav uas ua pov thawj qhov tshwm sim ntawm tus kab mob ntawm daim tawv nqaij uas tsis tuaj yeem kwv yees.
Tus kws tshawb fawbmuaj 3 yam ua rau yus chim siab:
- txo qis hauv tib neeg kev tiv thaiv, uas thaum kawg ua rau lub cev tsis muaj zog thiab tsis muaj zog tiv thaiv kab mob;
- genetic predisposition;
- teeb meem ntawm lub plab zom mov, lossis qhov ua txhaum ntawm kev nqus cov as-ham hauv cov hnyuv.
Dühring's dermatitis herpetiformis, kev kho mob uas yuav piav qhia hauv qab no, hais txog cov kab mob autoimmune ntawm daim tawv nqaij. Yog li ntawd, nyob rau hauv tus txheej txheem ntawm kev kho mob, feem ntau cov kws kho mob tsim cov kev cai uas sib haum mus rau lub algorithm rau kev kho mob ntawm autoimmune ntshawv siab.
Nws tseem yuav tsum tau muab sau tseg tias hauv qee tus neeg mob, thaum lub sijhawm kuaj, kev tsis haum rau gluten, uas muaj ntau tshaj hauv cov nplej, tau tshwm sim. Lub hauv paus chiv keeb autoimmune ntawm tus kab mob no kuj tau qhia los ntawm qhov tseeb tias IgA cov tshuaj tiv thaiv feem ntau pom nyob nruab nrab ntawm daim tawv nqaij thiab dermis.
Nws tseem yuav tsum tau hais tias kev txhim kho ntawm cov kab mob dermatosis tuaj yeem ua rau cov txheej txheem inflammatory hauv plab hnyuv, kab mob kab mob, nce iodine rhiab heev thiab ascariasis.
Dühring's dermatitis: Cov tsos mob
Zoo li txhua yam kab mob ntawm daim tawv nqaij, tus kab mob hauv nqe lus nug tau yooj yim pom los ntawm cov cim sab nraud. Nws feem ntau cuam tshuam rau kev sib deev muaj zog thaum muaj hnub nyoog 22-38 xyoo. Raws li cov poj niam, xws li dermatosis tsis cuam tshuam rau lawv ntau zaus.
Cov tsos mob tseem ceeb ntawm tus kab mob no yog qhov sib txawv hauv qab no:
- Eruptions ntawm daim tawv nqaij uas coj daim ntawv hlwv nrog kua hauv. Thaumkev loj hlob ntawm tus kab mob, xws li hlwv qhib, thiab crusts tsim nyob rau hauv lawv qhov chaw. Thaum combing, cov npuas tawg sai heev. Nyob rau tib lub sijhawm, lawv cov ntsiab lus tuaj yeem nkag mus rau ntawm daim tawv nqaij noj qab haus huv thiab kis mus rau nws, uas yuav ua rau muaj cov pob liab liab tshiab.
- khaus, mob thiab kub hnyiab ntawm qhov chaw ntawm pob khaus. Tus mob no yuam ib tug neeg mus khawb qhov teeb meem cheeb tsam, uas entails ib tug tseem ceeb nce nyob rau hauv cov pob liab liab.
- Thaum Dühring's dermatitis thawj zaug tshwm khaus, thiab tom qab ntawd pom thawj cov hlwv.
- Teeb meem nrog cov hnyuv hauv tus neeg mob tau qhia los ntawm cov rog ntawm cov quav, uas tom qab kis tau cov xim grey.
Lwm yam cim ntawm kab mob ntawm daim tawv nqaij
Tus kab mob sab nraud yog tshwm sim los ntawm kev tsis zoo ntawm tus neeg mob kev noj qab haus huv, nws lub siab xav lossis qaug zog, nrog rau kev hloov pauv hauv lub cev kub.
Npaj cov ntsiab lus uas tau tshwm sim thaum lub sij hawm kev loj hlob ntawm tus kab mob no me me. Hauv qhov no, lawv hu ua vesicles. Yog hais tias lawv loj (nrog ib txoj kab uas hla ntawm 2 cm los yog ntau tshaj), ces cov kws kho mob hu lawv bullous pob.
Raws li cov kws tshaj lij, yog tias cov kua dej uas muaj nyob hauv cov hlwv ua rau huab dhau sijhawm, nws txhais tau tias tus kab mob tau koom nrog cov txheej txheem pathological.
Nws kuj yuav tsum tau muab sau tseg tias khawb twb tsim crusts sai sai no ua rau tsim ib tug erosive cheeb tsam uas yuav siv sij hawm qhov chaw ntawm lub qub npuas.
Diagnosis
Yuav ua li cas txheeb xyuas tus kab mob hauv nqe lus nug? Dab tsi yog qhov kev kuaj mobkev cai? Duhring's dermatitis yog txiav txim tau yooj yim heev. Rau qhov no, kev sim thiab cov cuab yeej siv tau siv. Cov no suav nrog cov hauv qab no:
- Kev txiav txim siab ntawm cov eosinophils hauv cov ntshav, nrog rau cov kua dej cystic (lawv tau nce ntau thaum muaj mob).
- Kev tshawb fawb ntawm cov thyroid caj pas (nyob rau hauv yuav luag 30% ntawm tag nrho cov mob, kuaj pom muaj ntau yam kab mob).
- Direct immunofluorescence kuaj pom kev sib sau ntawm cov immunoglobulins ruaj khov A.
- Test nrog iodine. Cov txheej txheem kuaj mob no yog ua raws li hauv qab no: ib qho tshuaj pleev uas muaj 50% poov tshuaj iodide yog siv rau lub hauv pliaj, uas tau tso tseg rau ib hnub. Nrog rau qhov kev kuaj pom zoo, pob khaus thiab liab tshwm nyob rau hauv qhov chaw no.
Kev kho mob ntawm Dühring's dermatitis
Ua ntej pib kho, cov neeg mob uas muaj Dühring's dermatitis tau ua tib zoo tshuaj xyuas cov kab mob plab hnyuv thiab cov qog nqaij hlav malignant. Lawv kuj tau muab tshuaj "Dapson". Nws cov koob tshuaj yog 100 mg ob zaug ib hnub rau 5 hnub nrog 2-hnub so (3-5 cycles txhua).
Tom qab kev ploj ntawm cov tsos mob ntawm tus kab mob, cov tshuaj no tau muab tshuaj rau hauv ib koob tshuaj, uas yog, 5 mg txhua hnub lossis 2 zaug hauv ib lub lis piam. Cov kev mob tshwm sim ntawm cov tshuaj nyob rau hauv nqe lus nug muaj xws li xeev siab, ntuav, anemia, psychosis, daim siab puas thiab tsis haum tshuaj. Nws tseem yuav tsum tau muab sau tseg tias Dapsone yog incompatible nrog barbiturates thiab Amidopyrine.
Dhau li ntawm cov tshuaj hais, rau kev kho mob dermatosisKuj tseem siv tau cov tshuaj xws li lipoic acid, sodium dimeracoptopropanesulfonate, antihistamines, etebenecid, methionine, vitamins (rutoside, ascorbic acid, B vitamins).
Khoom noj khoom haus rau tus neeg mob
Dühring's dermatitis kho tau li cas? Yuav tsum noj zaub mov rau tus kab mob no. Cov neeg mob tau pom kev noj zaub mov tshwj tsis yog oats, hom qoob mog, millet thiab barley, nrog rau lwm yam cereals. Tsis tas li ntawd, cov neeg mob Dühring's dermatitis raug txwv tsis pub noj zaub mov uas muaj iodine (piv txwv li, ntses hiav txwv).
Kev Ntsuas thiab Kab Mob
Cov kab mob hauv nqe lus nug yog voj voog thiab ntev. Raws li txoj cai, nws yog nrog los ntawm kev ua tsis tiav thiab luv luv remissions. Txawm hais tias qee tus neeg mob tseem pom qhov ua tiav thiab kev tso cai ywj pheej.
Thaum kho Dühring's dermatitis, tus neeg mob tuaj yeem tsim pob pob tshiab. Txawm li cas los xij, tus mob no tsis yog qhov qhia txog kev hloov pauv (nrog rau kev nce ntxiv) hauv cov tshuaj noj txhua hnub.
Nyob rau hauv cov neeg mob feem ntau raug mob los ntawm cov kab mob ntawm daim tawv nqaij, nruj ua raws li kev noj haus ua rau muaj kev txhim kho tseem ceeb ntawm tus mob. Txawm li cas los xij, qhov no tsis txo qhov xav tau ntawm Dapsone.
